• NSAIDs
  • Research suggested most of the adverse effects of NSAIDs to be mediated by blocking the COX1 (constitutive) enzyme, with the analgesic effects being mediated by the COX2 (inducible) enzyme. (wikipedia.org)
  • These drugs (such as rofecoxib, celecoxib, and etoricoxib) are equally effective analgesics when compared with NSAIDs, but cause less gastrointestinal hemorrhage in particular. (wikipedia.org)
  • pain
  • Analgesics was one of the best performing OTC areas in 2010 as it offers products that provide a quick and effective solution to pain. (marketpublishers.com)
  • An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain. (wikipedia.org)
  • the World Health Organization (WHO) pain ladder specifies mild analgesics as its first step. (wikipedia.org)
  • Pain sometimes resolves promptly once the underlying trauma or pathology has healed, and is treated by one practitioner, with drugs such as analgesics and (occasionally) anxiolytics. (wikipedia.org)
  • growth
  • In addition, economic growth goes hand-in-hand with working long hours and high stress levels, resulting in an increase in demand for analgesics. (sbwire.com)
  • effects
  • In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. (wikipedia.org)
  • Boston
  • Boston, MA -- ( SBWIRE ) -- 06/15/2012 -- As a result of climate change in Colombia the winter and summer months have become extended, leading to more diseases and an increase in demand for analgesics. (sbwire.com)