• epidural
  • Minimal analgesic concentration of a local anesthetic (MAC-LA) is the median effective concentration of a local anesthetic during the first stage of labor and corresponds to the concentration infused in the epidural space that will induce analgesia in 50% of patients (EC 50 ) 1 . (scielo.br)
  • Patients
  • Dexmedetomidine in combination with fentanyl-based IV-PCA significantly improved postoperative analgesia in patients undergoing open gastrectomy without hemodynamic instability, which was comparable to thoracic E-PCA. (medsci.org)
  • It is also used in surgery and post operative pain control in patients that are taking high dose buprenorphine for chronic pain because it is the only opioid that has a potency and binding affinity strong enough to displace buprenorphine from the opioid receptors in the central nervous system and provide analgesia. (wikipedia.org)