Clusters by season and locality reveal a striking epidemiological overlap between sporadic schizophrenia and multiple sclerosis (MS). As the birth excesses of those individuals who later in life develop schizophrenia mirror the seasonal distribution of Ixodid ticks, a meta analysis has been performed between all neuropsychiatric birth excesses including MS and the epidemiology of spirochaetal infectious diseases. (biomedcentral.com)
Alzheimer disease (AD) is an acquired disorder of cognitive and behavioral impairment that markedly interferes with social and occupational functioning. (medscape.com)
Coronal T1-weighted magnetic resonance imaging (MRI) scan in a patient with moderate Alzheimer disease. (medscape.com)
Alternative medicine practitioners claim that Lyme infection can become chronic and attribute a vague constellation of symptoms not unlike the vague constellation of symptoms attributed to adrenal fatigue to chronic Lyme infection, a condition they commonly refer to as chronic Lyme disease . (scienceblogs.com)
However, there is no evidence that this syndrome is caused by chronic B. burgdorferi infection, nor is there any good evidence that prolonged treatment with antibiotics benefits patients with persistent symptoms after treatment for Lyme disease-quite the contrary, actually. (scienceblogs.com)
At least five five randomized, placebo-controlled studies have shown that prolonged courses of IV antibiotics do not improve long-term outcome for patients with a diagnosis of chronic Lyme disease (e.g., this one ). (scienceblogs.com)
These potential complications have been illustrated in a recent article in the CDC's Morbidity and Mortality Weekly Report (MMWR), Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease . (scienceblogs.com)
The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2). (scienceblogs.com)
Patients with a diagnosis of chronic Lyme disease have been provided a wide range of medications as treatment, including long courses of intravenous (IV) antibiotics (3,4). (scienceblogs.com)
Infection3
A group of physicians who like to refer to themselves as "Lyme literate" physicians describe patients whom they believe have persistent B. burgdorferi infection, claiming that the condition requires long-term antibiotic treatment. (scienceblogs.com)
Now, there is a condition known as posttreatment Lyme disease syndrome, which is the proper term for patients with a verified previous B. burgdorferi infection who experience fatigue, arthralgias, or other symptoms six months or more after antibiotic treatment when all other conditions have been ruled out. (scienceblogs.com)
This review focuses specifically on infection with Chlamydophila (Chlamydia) pneumoniae in LOAD and how this infection may function as a 'trigger or initiator' in the pathogenesis of this disease. (semcs.net)
Symptoms3
Lyme disease symptoms include fever, headache, and fatigue, and it's characterized by a skin rash known as erythema migrans. (scienceblogs.com)
The diagnosis of Lyme disease is based o nits symptoms, physical findings (e.g., the characteristic skin rash, which looks like a bull's eye), and a history of being in an area where exposure to ticks is possible. (scienceblogs.com)
Yet these "Lyme literate" physicians and a coterie of naturopaths treat patients with symptoms after Lyme disease for weeks, months, or even years of antibiotics, and there are many known complications to long term antibiotic treatment. (scienceblogs.com)
Epidemiology1
The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. (semcs.net)
Severe1
Sporadic, late-onset Alzheimer's disease (LOAD) is a non-familial, progressive neurodegenerative disease that is now the most common and severe form of dementia in the elderly. (semcs.net)
Presence1
Alzheimer and a number of other neurodegenerative diseases are characterized by the presence of reactive microglia and reactive astrocytes in association with the lesions. (semcs.net)
Treatment1
The usual treatment for Lyme disease is 2-4 weeks of antibiotics , which is highly effective. (scienceblogs.com)
Progressive1
It is an incurable disease with a long and progressive course. (medscape.com)