• Ampicillin and Sulbactam for Injection, USP is an injectable antibacterial combination consisting of the semisynthetic antibacterial ampicillin sodium and the beta-lactamase inhibitor sulbactam sodium for intravenous and intramuscular administration. (nih.gov)
  • Ampicillin sodium is derived from the penicillin nucleus, 6-aminopenicillanic acid. (nih.gov)
  • Sulbactam sodium is a derivative of the basic penicillin nucleus. (nih.gov)
  • Ampicillin and Sulbactam for Injection, USP, ampicillin sodium/sulbactam sodium parenteral combination is available as a white to off-white dry powder for reconstitution. (nih.gov)
  • Ampicillin and Sulbactam for Injection, USP dry powder is freely soluble in aqueous diluents to yield pale yellow to yellow solutions containing ampicillin sodium and sulbactam sodium equivalent to 250 mg ampicillin per mL and 125 mg sulbactam per mL. (nih.gov)
  • 1.5 g of Ampicillin and Sulbactam for Injection, USP (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt) parenteral contains approximately 115 mg (5 mEq) of sodium. (nih.gov)
  • J0295 is a valid 2023 HCPCS code for Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm or just " Ampicillin sulbactam 1.5 gm " for short, used in Medical care . (hcpcs.codes)
  • The recommended adult dosage of UNASYN is 1.5 g (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt) to 3 g (2 g ampicillin as the sodium salt plus 1 g sulbactam as the sodium salt) every six hours. (pfizermedicalinformation.com)
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  • Perioperative use of ampicillin/sulbactam, cefoxitin and piperacillin/ metronidazole in elective colon and rectal surgery. (bvsalud.org)
  • Perioperative Anwendung von Ampicillin/Sulbactam, Cefoxitin und Piperacillin/Metronidazol in der elektiven Colon- und Rectumchirurgie. (bvsalud.org)
  • Ampicillin is in a class of medications called penicillin-like antibiotics. (medlineplus.gov)
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  • ampicillin for amoxicillin and amoxicillin-clavulanic acid for ampicillin-sulbactam. (vin.com)
  • The impact on clavulanic acid and sulbactam is not clear, although their use in place of cephalosporins appears to reduce the emergence of ESBL and may reduce the emergence of other resistant pathogens such as Clostridium difficile and vancomycin-resistant enterococci. (vin.com)
  • It is not yet known whether relevant antibiotic concentrations can be reached in the jawbone of patients with osteonecrosis of the jaw after intravenous application of ampicillin/sulbactam. (uni-wuerzburg.de)
  • Suspecting a possible secondary bacterial infection at the beginning, intravenous antibiotic treatment with ampicillin/sulbactam was initiated. (nih.gov)
  • If ampicillin/sulbactam was not marketed, amoxicillin/clavulanate 500mg to 2g every 6 hours was used. (renalandurologynews.com)
  • Manually determine the antibiotic susceptibility of microorganisms using Antimicrobial Susceptibility Testing (AST) methods in conjunction with reliable, easy-to-use Thermo Scientific™ Oxoid™ Ampicillin/Sulbactam Antimicrobial Susceptibility Disks. (labmal.com)
  • Ampicillin/sulbactam versus cefuroxime as antimicrobial prophylaxis for cesarean delivery: a randomized study. (druglib.com)
  • Comparison of ampicillin-sulbactam/macrolide dual therapy versus fluoroquinolone monotherapy in hospitalized patients with community-acquired pneumonia]. (nih.gov)
  • Eighty-five (48.3%) received cefuroxime prophylaxis and 91 (51.7%) ampicillin/sulbactam. (druglib.com)
  • Postoperative infection developed in 5 of 86 (5.9%) patients that received cefuroxime compared to 8 of 91 (8.8%) patients that received ampicillin/sulbactam (p=0.6). (druglib.com)
  • CONCLUSIONS: Ampicillin/sulbactam was as safe and effective as cefuroxime when administered for the prevention of infections following cesarean delivery. (druglib.com)
  • Ampicillin serum levels are similar to those produced by the administration of equivalent amounts of ampicillin alone. (nih.gov)
  • Peak ampicillin serum levels ranging from 109 to 150 mcg/mL are attained after administration of 2000 mg of ampicillin plus 1000 mg sulbactam and 40 to 71 mcg/mL after administration of 1000 mg ampicillin plus 500 mg sulbactam. (nih.gov)
  • The corresponding mean peak serum levels for sulbactam range from 48 to 88 mcg/mL and 21 to 40 mcg/mL, respectively. (nih.gov)
  • Somewhat higher and more prolonged serum levels of ampicillin and sulbactam can be achieved with the concurrent administration of probenecid. (nih.gov)
  • An excellent example is the recent demonstration of substantially higher ampicillin/sulbactam resistance in a center where abdominal trauma patients repeatedly received ampicillin/sulbactam. (medscape.com)
  • In patients with impaired renal function the elimination kinetics of ampicillin and sulbactam are similarly affected, hence the ratio of one to the other will remain constant whatever the renal function. (nih.gov)
  • Schematic illustrations of the experimental setups used to create admixtures to assess the physical compatibility of enrofloxacin at various dilutions with saline (0.9% NaCl) solution, PLA, LRS, HES, metoclopramide, and ampicillin-sulbactam. (avma.org)
  • B-In the second experiment, the apparatus setup was the same as that for the first experiment except a second syringe pump was used to infuse metoclopramide (2 mg/kg/d) or ampicillin-sulbactam (30 mg/kg) through an IV extension set, which was connected to the IV set through which saline solution (40 mL/kg/d) was infused. (avma.org)