PolymerCollagen fiber networkProteinMechanicalConnectiveSynthesisSilkFlexibilityStructureTissueReturn to its originalPresentSmoothBodyMadeCellsFunctionNarrowSupplyImportantHighCollagenExtracellular matrixGrapheneBiodegradableNanoProteinsElasticSolubleFeasibilityIntermediateStrainHelpsDomainsPropertiesFormResearch
Polymer2
- In order to exploit the pharmacological potential of natural bioactive molecules with low water solubility, such as curcumin, it is necessary to develop formulations, such as amorphous polymer dispersions, which allow a constant release rate and at the same time avoid possible toxicity effects of the crystalline form of the molecule under scrutiny. (ibecbarcelona.eu)
- Curcumin has significantly higher glass transition temperature Tg (≈ 347 K) than the polymer matrix (≈274-277 K depending on the molecular weight), and dispersions displayed Tg's intermediate between those of the pure amorphous components, implying that curcumin acts as an effective antiplasticizer for PADAS. (ibecbarcelona.eu)
Collagen fiber network2
- It is an extract rich in alkylamides that stimulate fibroblast activity, support the collagen fiber network and restore firmness and smoothness to the skin. (freshlycosmetics.com)
- Furthermore, the dressing modulated the inflammatory responses, stimulated the activation and proliferation of fibroblasts, and enhanced rapid production of collagen fiber network with a consequently shorter healing time. (afpm.org.my)
Protein6
- Elastin is a protein that in humans is encoded by the ELN gene. (wikipedia.org)
- The ELN gene encodes a protein that is one of the two components of elastic fibers. (wikipedia.org)
- Elastin is a very long-lived protein, with a half-life of over 78 years in humans. (wikipedia.org)
- Elastin is made by linking together many small soluble precursor tropoelastin protein molecules (50-70 kDa), to make the final massive, insoluble, durable complex. (wikipedia.org)
- It is richly vascularized, it also contains blood and lymph vessels, nerves, skin appendages, inflammatory mediators and immune cells, fibroblasts and Collagen and Elastin, protein fibers providing respectively mechanical strength and elasticity to return to its original size after a traction. (kleraderm.com)
- The reports on base sequences of spider silk protein genes have gained importance as the mechanical properties of silk fibers have been revealed. (bioone.org)
Mechanical3
- Elastin is also an important load-bearing tissue in the bodies of vertebrates and used in places where mechanical energy is required to be stored. (wikipedia.org)
- It is converted into silk fibers at the silkworm's spinnerets under mechanical forces including shear stress and pressure. (bvsalud.org)
- Further expansion of these uses builds on the excellent mechanical strength of SF fiber, which derives from its structure. (bvsalud.org)
Connective3
- In the body, elastin is usually associated with other proteins in connective tissues. (wikipedia.org)
- Electron micrograph of a bundle of skeletal muscle fibers wrapped in connective tissue. (earthwormexpress.com)
- The types and characteristics of muscle fiber and connective tissue proteins are described in the next sections. (earthwormexpress.com)
Synthesis2
- The unlinked tropoelastin molecules are not normally available in the cell, since they become crosslinked into elastin fibres immediately after their synthesis by the cell and export into the extracellular matrix. (wikipedia.org)
- It works deeply on the tight junctions between cells, protecting the synthesis of collagen and elastin and stimulating the vascularisation process to increase the supply of nutrients and oxygen to the cells. (freshlycosmetics.com)
Silk4
- However, the detailed mechanism of the structural transition of liquid silk to silk fibers under pressure is not well understood. (bvsalud.org)
- Silk fibroin (SF) fiber from the silkworm Bombyx mori in the Silk II form has been used as an excellent textile fiber for over 5000 years. (bvsalud.org)
- In order to produce spider silk with a highly hydrophobic character, based on the sequence of ADF-3 silk, we produced recombinant silk (RSSP(VLI)) where all QQ sequences were replaced by VL, while single Q was replaced by I. The artificial RSSP(VLI) fiber was prepared using formic acid as the spinning solvent and methanol as the coagulant solvent. (bvsalud.org)
- The dimensional stability and water absorption experiments of the fiber were performed for eight kinds of silk fiber. (bvsalud.org)
Flexibility1
- The feasibility of using recombinant human tropoelastin to enable elastin fiber production to improve skin flexibility in wounds and scarring has been studied. (wikipedia.org)
Structure2
- It is concluded that conformational disorder is a constitutive feature of elastin structure and function. (wikipedia.org)
- Nematodes and many other non-chordate animals seem to have only type VI intermediate filaments , fibers that structure the nucleus . (wikipedia.org)
Tissue1
- Comparison between fresh and digested tissues shows that, at 35% strain, a minimum of 48% of the arterial load is carried by elastin, and a minimum of 43% of the change in stiffness of arterial tissue is due to the change in elastin stiffness. (wikipedia.org)
Return to its original1
- Elastin helps skin to return to its original position when it is poked or pinched. (wikipedia.org)
Present1
- Electron microscopy of the skin shows that the diameter of dermal collagen fibrils is decreased and that sparse, amorphous elastin fibers are present. (medscape.com)
Smooth1
- Skeletal and smooth muscle cells are elongated, called muscle fibers and cardiac muscle cells are not. (earthwormexpress.com)
Body1
- Elastic fiber in the body is a mixture of amorphous elastin and fibrous fibrillin. (wikipedia.org)
Made2
- These fibers are immersed in the fundamental or amorphous substance mainly made by glycosaminoglycans, including Hyaluronic Acid able to bind water molecules giving hydration and firmness to the tissues. (kleraderm.com)
- A remarkable decrease in the motion of the fiber in water was made evident by 13C solid-state NMR. (bvsalud.org)
Cells2
- Muscle cells, called muscle fibers, are long, narrow, very specialized cells covered by the cell membrane (sarcolemma), whose cytoplasm (sarcoplasm) contains the organelles and the structures responsible of muscle contraction, the myofibrils. (earthwormexpress.com)
- Skeletal muscle fibers are the longest muscle cells and have striations or stripes. (earthwormexpress.com)
Function1
- Elastin serves an important function in arteries as a medium for pressure wave propagation to help blood flow and is particularly abundant in large elastic blood vessels such as the aorta. (wikipedia.org)
Narrow1
- The twisting of the hair fiber creates the illusion of wide and narrow areas along the hair shaft similar to the nodes of monilethrix. (medscape.com)
Supply1
- As muscle is converted to meat, the muscle fibers modify their metabolism in order to adapt to the new conditions (absence of oxygen and nutrient supply, lack of residues removing), and as a consequence, many changes occur. (earthwormexpress.com)
Important1
- When we use it as a biomaterial or material for textiles, it is important to suppress the effect of water on the fiber by as much as possible in order to maintain dimensional stability. (bvsalud.org)
High1
- RSSP(VLI) fiber showed high dimensional stability, which is suitable for textiles. (bvsalud.org)
Collagen13
- Electron microscopy of the skin shows that the diameter of dermal collagen fibrils is decreased and that sparse, amorphous elastin fibers are present. (medscape.com)
- The right panel is a schematic representation of the extracellular matrix of the alveolar septal wall with various components including amorphous elastin (El), wavy collagen (C), complex proteoglycans (PG), basement membrane (BM) and fibroblast cells (F). (Drawing by E. Bartolák‐Suki). (comprehensivephysiology.com)
- It can be seen that some fibers are comprised of almost exclusively type I or type III collagen (black arrows), whereas at several locations, the two collagen types also appear to co‐localize suggesting that they mix and form composite fibers (red arrow) where the color is intermediate between blue and brown. (comprehensivephysiology.com)
- Electron microscope images of ECM sheets containing both collagen and elastin at 0% (A) and 30% (B) uniaxial strain. (comprehensivephysiology.com)
- Arrows denote collagen fibers and the white regions are elastin. (comprehensivephysiology.com)
- Silica plays a pivotal role in collagen synthesis and the production of elastin and keratin. (nutritioninsight.com)
- The natural weave of elastin (green) and collagen (yellow) are evident when viewed under a microscope. (materialstoday.com)
- Elastin gives periosteum its stretchy properties and collagen imparts toughness. (materialstoday.com)
- A complex arrangement of collagen, elastin and other structural proteins gives periosteum amazing resilience and provides bones with added strength under high impact loads. (materialstoday.com)
- The challenge with using collagen and elastin is their fibers, that are too small to fit into the loom. (materialstoday.com)
- So we used elastic material that mimics elastin and silk that mimics collagen,' said Knothe Tate. (materialstoday.com)
- In a first test of the scaled-up tissue weaving concept, a series of textile swatch prototypes were woven, using specific combinations of collagen and elastin in a twill pattern designed to mirror periosteum's weave. (materialstoday.com)
- Mechanical testing of the swatches showed they exhibited similar properties to those found in periosteum's natural collagen and elastin weave. (materialstoday.com)
Extracellular matrix3
- Elastin is a key component of the extracellular matrix in gnathostomes (jawed vertebrates). (wikipedia.org)
- The unlinked tropoelastin molecules are not normally available in the cell, since they become crosslinked into elastin fibres immediately after their synthesis by the cell and export into the extracellular matrix. (wikipedia.org)
- A) Longitudinal sections of elastin‐rich extracellular matrix sheets stained with acid Orcein at 0% strain (top) and 30% uniaxial strain in the horizontal direction (bottom). (comprehensivephysiology.com)
Graphene1
- Our research focused on developing novel printable formulations using a gelatin/pectin polymeric matrix that integrate synergistic reinforcement components i.e. graphene oxide (GO) and oxidized nanocellulose fibers (CNF). (regenhu.com)
Biodegradable2
Nano5
- His primary research interests are in biophysical chemistry, nano-materials, biopolymers and the general field of disordered or amorphous materials. (asu.edu)
- Systems currently under investigation include spider silk fibers and biopolymers, protein clusters, polyamorphic materials, nano-particles and quantum dots, battery and fuel cell materials, and most recently diabetes related research. (asu.edu)
- EquiSil then provides the complex of these polysaccharides and silica in biogenic amorphous nano-form. (nutritioninsight.com)
- The amorphous and nano characteristics contribute to better absorption of silica from EquiSil. (nutritioninsight.com)
- It consists of highly ordered domains (nano crystals) and amorphous regions. (lu.se)
Proteins1
- In the body, elastin is usually associated with other proteins in connective tissues. (wikipedia.org)
Elastic3
- The ELN gene encodes a protein that is one of the two components of elastic fibers. (wikipedia.org)
- Elastic fiber in the body is a mixture of amorphous elastin and fibrous fibrillin. (wikipedia.org)
- Elastin serves an important function in arteries as a medium for pressure wave propagation to help blood flow and is particularly abundant in large elastic blood vessels such as the aorta. (wikipedia.org)
Soluble3
- Elastin is made by linking together many small soluble precursor tropoelastin protein molecules (50-70 kDa), to make the final massive, insoluble, durable complex. (wikipedia.org)
- FiberGG combines a scientifically proven soluble fiber with a highly researched probiotic strain to help move food through the digestive tract, mainta. (lifestreamgroup.com)
- Bioactive Organic Fiber is a scientifically proven soluble fiber which helps move food through the digestive tract to maintain digestive health and mi. (lifestreamgroup.com)
Feasibility2
- The feasibility of using recombinant human tropoelastin to enable elastin fiber production to improve skin flexibility in wounds and scarring has been studied. (wikipedia.org)
- We have also demonstrated the feasibility of using this technique to test other fibers to produce a whole range of new textiles. (materialstoday.com)
Intermediate1
- Nematodes and many other non-chordate animals seem to have only type VI intermediate filaments , fibers that structure the nucleus . (cloudfront.net)
Strain2
- Comparison between fresh and digested tissues shows that, at 35% strain, a minimum of 48% of the arterial load is carried by elastin, and a minimum of 43% of the change in stiffness of arterial tissue is due to the change in elastin stiffness. (wikipedia.org)
- Note the straightening and thinning of the elastin fibers with increased strain. (comprehensivephysiology.com)
Helps1
- Elastin helps skin to return to its original position when it is poked or pinched. (wikipedia.org)
Domains1
- The hydrophilic domains contain Lys-Ala (KA) and Lys-Pro (KP) motifs that are involved in crosslinking during the formation of mature elastin. (wikipedia.org)
Properties1
- With a unique combination of high elasticity, mechanical strength and toughness, its superior material properties surpass those of any currently known man-made fiber. (asu.edu)
Form1
- Elastosis is the buildup of elastin in tissues, and is a form of degenerative disease. (wikipedia.org)
Research1
- Nordforsk Nordic Neutron Science Programme ( https://www.nordforsk.org/en/programmes-and-projects/programmes/joint-nordic-programme-for-neutron-research ) via the Nordic Network for Soft and Biological Matter. (lu.se)