• ligand
  • 21. A method of promoting anabolic bone growth in a subject, the method comprising administering to the subject a biased ligand for the parathyroid hormone (PTH)/PTH-related protein receptor (PTH1R) in an amount sufficient to effect promotion of anabolic bone growth. (patentsencyclopedia.com)
  • 28. A method of treating a bone disorder, the method comprising administering to a subject in need thereof a biased ligand for the PTH1 receptor, in an amount sufficient to treat the bone disorder. (patentsencyclopedia.com)
  • CXCR4 ligand analogs containing a non-natural amino acid photocrosslinker, benzophenylalanine and a biotin tag for complex isolation were chemically synthesized and crosslinked to CXCR4 expressed on intact cells. (ubc.ca)
  • Individual components of the receptor-ligand complex were identified by western blotting and tandem mass spectrometry. (ubc.ca)
  • Regions on the bound receptor that were protected from protease treatment and consequently tandem MS/MS sequencing were identified as potential sites of ligand-receptor contact. (ubc.ca)
  • These regions were identified as the receptor N-terminus and/or the first extracellular loop for ligand binding/docking. (ubc.ca)
  • method
  • 8. A method of treating breast cancer, comprising administering to a patient in need of treatment an effective dose of HGFIN with an amino acid sequence of SEQ ID NO:2 in a pharmaceutically acceptable carrier. (patentsencyclopedia.com)
  • internal
  • Pain can be experienced when the free nerve endings which constitute the pain receptors in the skin as well as in certain internal tissues are subjected to mechanical, thermal or chemical stimuli. (google.com)