• immunity
  • enhancing Toll-like receptor ligand adjuvants, such as monophosphoryl lipd A (MPL or CpG to alum might reduce the Th2-skewing activity of alum and balance host immunity to reduce the development of allergic disease. (deadlyallergy.com)
  • Aluminium-derived adjuvants are often used in clinical trials and have the reputation of safety and the facilitation of long-lasting antibody responses [ 1 ], but the effect on cell-mediated immunity remains questionable when used along with small immunogenic antigens. (biomedcentral.com)
  • depot
  • However, four subsequent lines of evidence indicate that a depot effect is likely not important for the adjuvant effect of alum. (frontiersin.org)
  • immune response
  • Adjuvants may be added to a vaccine to modify the immune response by boosting it such as to give a higher amount of antibodies and a longer-lasting protection, thus minimizing the amount of injected foreign material. (wikipedia.org)
  • Adjuvants may also be used to enhance the efficacy of a vaccine by helping to modify the immune response to particular types of immune system cells: for example, by activating T cells instead of antibody-secreting B cells depending on the purpose of the vaccine. (wikipedia.org)
  • An adjuvant can also act as an irritant, which engages and amplifies the body's immune response. (wikipedia.org)
  • addition
  • In addition, concerns have been raised regarding whether adjuvants may be able to trigger responses to self-proteins causing autoimmunity. (wikipedia.org)
  • different
  • A magazine article about vaccine adjuvants in 2007 was headlined "Deciphering Immunology's Dirty Secret" to refer to the early days of vaccine manufacture, when significant variations in the effectiveness of different batches of the same vaccine were observed, correctly assumed to be due to contamination of the reaction vessels. (wikipedia.org)
  • Alum formulations are particulate in nature, to which the vaccine antigens are adsorbed, albeit with distinct characteristics among the different forms of alum salts ( 2 ). (frontiersin.org)
  • These immune responses may be modulated by presenting the antigens together with different types of adjuvants as well as through the route of administration. (ahajournals.org)
  • research
  • I am unaware of any research showing how quickly cysts can develop after immunization with an oil adjuvant. (whale.to)