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  • caapi vine
  • contradictory] The caapi vine itself was the subject of a dispute between U.S. entrepreneur Loren Miller and the Coordinating Body of Indigenous Organizations of the Amazon Basin (COICA). (wikipedia.org)
  • It has been reported that some effects can be felt from consuming the caapi vine alone, but that DMT-containing plants (such as Psychotria ) remain inactive when drunk as a brew without a source of monoamine oxidase inhibitor (MAOI) such as B. caapi . (infogalactic.com)
  • MAOI
  • When these 2 plants are combined, however, the MAOI activity of the vine allows the DMT to cross into the brain, which in turn leads to the visionary effect that many users report experiencing. (ndnr.com)
  • brew
  • Ayahuasca which means 'the vine of the soul' is a powerfully psychoactive brew which is thought to have been used for several hundred years by indigenous people in the Amazon. (medindia.net)
  • The vine and the ayahuasca brew are legal ambiguities, since nowhere in the Controlled Drugs and Substances Act is it stated that natural material containing a scheduled substance is illegal, a position supported by the United Nations International Narcotics Control Board. (wikipedia.org)
  • tryptamine
  • The difficulty distinguishing between L-tryptophan and free tryptamine as the precursor of harmine biosynthesis originates from the presence of the serotonin biosynthetic pathway, which closely resembles that of harmine, yet necessitates the availability of free tryptamine as its precursor. (wikipedia.org)
  • As such, it is unclear if the decarboxylation of L-tryptophan, or the incorporation of pyruvate into the basic tryptamine structure is the first step of harmine biosynthesis. (wikipedia.org)
  • Passiflora
  • Passiflora, known also as the passion flowers or passion vines, is a genus of about 550 species of flowering plants, the type genus of the family Passifloraceae. (wikipedia.org)
  • woody
  • the latter is the Portuguese word for liana (or woody climbing vine). (wikipedia.org)
  • For example, the Chilean passion flower (P. pinnatistipula) is a rare vine growing in the Andes from Venezuela to Chile between 2,500 and 3,800 meters altitude, and in Coastal Central Chile, where it occurs in woody Chilean Mediterranean forests. (wikipedia.org)
  • Malpighiaceae
  • Callaeum antifebrile is a South American jungle vine of the family Malpighiaceae which occurs predominantly throughout the Upper Amazon basin, and less frequently along the Lower Amazon. (wikipedia.org)
  • synthetic
  • Unlike many synthetic pharmaceutical MAOIs such as phenelzine, harmine is reversible and selective meaning it does not have nearly as high a risk for the "cheese syndrome" caused by consuming tyramine-containing foods, which is a risk associated with monoamine oxidase A inhibitors, but not monoamine oxidase B inhibitors. (wikipedia.org)
  • Harmine has not been the subject of much clinical research in the treatment of depression, which could be due in part to its restricted legal status in many countries, as well as the existence of synthetic MAOIs with fewer side effects. (wikipedia.org)
  • found
  • With the radioisotope carbon-11 harmine is used in positron emission tomography neuroimaging to examine its binding to MAO-A. Harmine found in root secretions of Oxalis tuberosa has been found to have insecticidal properties. (wikipedia.org)
  • Harmine has been found to increase EAAT2 glutamate pump expression in central nervous system, therefore reducing glutamate toxicity. (wikipedia.org)
  • made
  • The E. Merck Company made a film illustrating the chemistry and pharmacology of harmine, along with its effects in three Parkinsonian patients at the Heidelberg Clinic. (ucla.edu)
  • effects
  • He brought back samples of this drug and published the first scientific description of the effects of its active alkaloids. (wikipedia.org)
  • medicine
  • agahuasca ayahuasca negro bejuco de las calenturas ("fever vine") caabi pajezinho shillinto shillinto blanco shillinto negro Callaeum antifebrile is used in folk medicine, particularly in the northern Brazilian state of Pará. (wikipedia.org)