This group also includes some related compounds with neutral and even weakly acidic properties. (wikipedia.org)
A rather heterogeneous group, these compounds have different chemical structures, different mechanisms of action, and different adverse effects. (medscape.com)
Plants3
Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals. (wikipedia.org)
Alkaloid-containing plants have been used by humans since ancient times for therapeutic and recreational purposes. (wikipedia.org)
Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. (wikipedia.org)
Similar2
Less similar and more toxic is A. pantherina, the Panther Cap. (sacredearth.com)
Some synthetic compounds of similar structure may also be termed alkaloids. (wikipedia.org)
Substances5
Independent researchers from England, Japan and Switzerland determined that it is these substances that cause the toxic and hallucinogenic effects, not muscarine. (agfonds.lv)
The present study aims to develop a forensic toxicological library to identify 56 natural toxic substances by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry (LC-QTOF-MS/MS). (springermedizin.de)
This library will be more effective for the screening of natural toxic substances in routine forensic toxicological analysis. (springermedizin.de)
To our knowledge, there are no reports dealing with development of library for natural toxic substances by LC-QTOF-MS/MS. (springermedizin.de)
In other words, when it comes to mixing psychoactive substances, the sum is more often than not different from the sum of its parts. (qualiacomputing.com)
Hydrogen1
In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen or sulfur. (wikipedia.org)
Humans2
Although alkaloids act on a diversity of metabolic systems in humans and other animals, they almost uniformly evoke a bitter taste. (wikipedia.org)
Alkaloid-containing plants have been used by humans since ancient times for therapeutic and recreational purposes. (wikipedia.org)
Serotonin2
Natural compounds containing nitrogen in the exocyclic position (mescaline, serotonin, dopamine, etc.) are usually classified as amines rather than as alkaloids. (wikipedia.org)
For example, while 5-MeO-DMT is relatively safe when vaporized (save for egregiously negligent uses of the drug and the occasional drowning in one's own vomit), taking 5-MeO-DMT orally in combination with an MAOI leads to extremely toxic reactions, such as severe hypertensive symptoms, overheating, and serotonin syndrome . (qualiacomputing.com)
Organisms1
Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals. (wikipedia.org)
Drug2
LSD is the most potent psychoactive drug, with doses as low as 1-1.5 mcg/kg capable of producing psychedelic effects. (medscape.com)
Consequently, fly-agaric (whether it is thought-about in any respect) is regarded solely as a harmful and probably toxic 'drug', fairly than a path to the divine. (rmt-racing.com)
Natural1
The boundary between alkaloids and other nitrogen-containing natural compounds is not clear-cut. (wikipedia.org)
Time2
Muscarine was discovered way back in 1869, for a long time it was considered the hallucinogenic component of red fly myrrh. (agfonds.lv)
When drying the caps of the red fly myrtle, muscarine remains in them, but they are then used 2-3 caps at a time, the amount of muscarine that enters the body is so small that it is completely hidden by the effect of hallucinogenic ingredients. (agfonds.lv)
Chemical1
Ibotenic acid is a chemical compound found in the fruiting bodies of various fly myrrhs. (agfonds.lv)
Development2
A significant contribution to the chemistry of alkaloids in the early years of its development was made by the French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou, who discovered quinine (1820) and strychnine (1818). (wikipedia.org)
The development of the chemistry of alkaloids was accelerated by the emergence of spectroscopic and chromatographic methods in the 20th century, so that by 2008 more than 12,000 alkaloids had been identified. (wikipedia.org)