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Mice, Inbred StrainsAlbinismSpecies SpecificityCrosses, GeneticPlant ExtractsRats, WistarMice, Inbred DBARats, Inbred StrainsRadiation Injuries, ExperimentalMice, Inbred C57BLChromosome MappingAegleMice, Inbred C3HPhenotypeQuantitative Trait LociHibiscusMice, Inbred AKRSemecarpusDark AdaptationDisease Models, AnimalAphrodisiacsRubiaceaeMice, Inbred ALightPhytotherapyLipoxygenasesInbreedingBixaceaeSequence Analysis, DNAMelia azedarachGenetic LinkageChromosomes, MammalianMice, Inbred BALB CRetinal DegenerationMuridaeRetinaElectroretinographyGenetics, BehavioralPhotoreceptor CellsGenotypeGenetic VariationMalondialdehydeAnimals, Outbred StrainsMice, CongenicPhenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) EsterHeterophyidaeMutationTrematodaLiverAsparagus PlantLipid PeroxidationMydriasisOcimumRecombination, GeneticAllelesCatalaseOrgan SizeSperm CountAlbinism, OculocutaneousContraceptive Agents, MaleDisease SusceptibilityBody WeightMice, Inbred CBAAntioxidantsRats, Sprague-DawleyMolecular Sequence DataRNA, Ribosomal, 16SGenesTestisAlbinism, OcularTrematode InfectionsMedicine, African TraditionalRadiation-Protective AgentsHybridization, GeneticRhodopsinDNA, RibosomalMonophenol MonooxygenaseTime FactorsCell CountMethanolBacterial Typing TechniquesFlurothylRats, Mutant StrainsNigella sativaGenes, BacterialEscherichia coliQuantitative Trait, HeritableVirulenceAmino Acid SequencePhotoreceptor Cells, VertebrateMice, Mutant StrainsPolymerase Chain ReactionOxidative StressAnimals, LaboratoryBase SequenceGlutathioneTissue AdhesionsRats, Inbred BNNucleic Acid HybridizationPigmentation
RecombinantBALBC57BLEmbryonic stemWistarCharacteristicsMice and ratsCoatMale RatsMutationRabbitsLociLaboratory animalsBehavioralSsNHsdEstrusExperimentsToxicityProteinsMutantCongenitalCells derivedAlbinismColonySpontaneousExamplesBreedingGeneticHumansIncidenceMouseIl2rgMetabolicReductionCenterGroupsAverageDietBasisMethodCondition
Recombinant1
  • The F344/Stm rat is a parental strain of the LEXF/FXLE recombinant inbred (RI) strains. (nig.ac.jp)
BALB2
  • Halsey Bagg develops the BALB /c ( Bagg albino) mouse for behavioral experiments. (jax.org)
  • These mice have both BALB/c inbred and NIH(S) outbred stock in their genetic background. (vivobio.com)
C57BL11
  • Furthermore, 129-strain ES cells often contribute to the germline of the chimeras, and when breeding chimeras with C57BL/6 test mice, the dominant agouti color in offspring signifying germline transmission is also easily detected in the G1 generation litters. (umassmed.edu)
  • Depending upon the study, these mice often have to be backcrossed 9 more generations with C57BL/6 mice to place the mutant allele on an inbred C57BL/6 background. (umassmed.edu)
  • When these C57BL/6N-based JM8 cells were injected into blastocysts from albino mice, a high proportion of chimeras displayed ES cell contribution to both germline and somatic tissues. (umassmed.edu)
  • Experience has shown that injection of black C57BL/6N embryonic stem cells into albino C57BL/6J Tyrc-Brd blastocysts is a particularly favorable combination for germline transmission. (umassmed.edu)
  • However, a disadvantage of this combination is that a slightly mixed C57BL/6 genetic background (C57BL/6N x C57BL/6J) is produced when breeding the resulting chimeras with C57BL/6J Tyrc-Brd albino mice to test for germline transmission in the G1 generation. (umassmed.edu)
  • Of course, one could breed the chimeras with inbred C57BL/6N mice to maintain a pure C57BL/6N substrain background- but then one could not use coat color in the G1 generation to identify germline-transmitting chimeras, as all the offspring would be of a black coat color regardless of germline transmission. (umassmed.edu)
  • The non-agouti mutation in C57BL/6 strains is due to an 11.8 Kbp retrotransposon located in the first intron of the agouti gene that abolishes the expression of the Agouti gene. (umassmed.edu)
  • The Sanger group performed gene targeting in the JM8 ES cells to delete the retrotransposon from the agouti locus and restore agouti gene function, permitting the visualization of ES cell-derived mice on an inbred C57BL/6 background by agouti coat color. (umassmed.edu)
  • This approach allows you to maintain the inbred C57BL/6N status of the offspring. (umassmed.edu)
  • The UMass Chan Transgenic Animal Modeling Core (TAMC) also has JM8-strain ES cells for targeting, and routinely injects either JM8.F6-strain ES cells or JM8.A3-strain ES cells into albino C57BL/6J Tyrc-Brd blastocysts. (umassmed.edu)
  • Using a pair of black mice from the Granby farm, Little develops the C57BL and C57BR strains. (jax.org)
Embryonic stem1
  • The strain is now valued as a source of embryonic stem cells for making knockout mice. (jax.org)
Wistar5
  • In 1980, a spontaneous tremor mutant rat was found in the colony of Kyo:Wistar (Yamada, 1985). (kyoto-u.ac.jp)
  • Inbreeding of the Lewis rat is begun by Dr. Margaret Lewis from a Wistar stock. (inotivco.com)
  • The origin of Wistar-Imamichi rat is Wistar Institute Standard Strain Lot No. 1359. (or.jp)
  • Then, this strain was named Wistar-Imamichi and was introduced to the Institute for Animal Reproduction in 1964. (or.jp)
  • Forced swim test (FST) in adult male Wistar rats and tail suspension test (TST) in adult male Swiss albino mice were used to investigate antidepressant activity of vitamin D administered in single dose and multiple doses. (ijbcp.com)
Characteristics1
  • We conclude that although rats and opossums share many similar characteristics, including ecological niche, their divergent evolutionary heritage results in vastly different behavioral capabilities. (researchgate.net)
Mice and rats2
  • In mice and rats, females require mating stimulation for the maintenance of pregnancy. (nature.com)
  • one estimate of mice and rats used in the US alone in 2001 was 80 million. (wmflabs.org)
Coat1
  • The strain was developed by Shisa et al at the Saitama Cancer Center Research Institute from the F344/DuCrj strain (Charles River Japan, Inc.). The coat color is albino (c). (nig.ac.jp)
Male Rats1
  • Each of 60 weanling male rats was assigned to one of 6 experimental diet groups: Fermented and unfermented camel milk with AOM, fermented and unfermented bovine milk with AOM and positive (PC, AOM only) and negative (NC, saline vehicle only) control groups. (scialert.net)
Mutation5
  • The strain having a Endonuclease-induced mutation in Il2rg gene was established by TAL effector nuclease obtained from Dr. Yamamoto at Hiroshima University. (kyoto-u.ac.jp)
  • In F18 progeny, a rat which did not have tm mutation was separated and established as a control strain of WTC (NBRP No.0020). (kyoto-u.ac.jp)
  • Basic, for each and every the brand new mutation had to be bred towards the a strain having almost every other phenotypic markers. (kenyan.bible)
  • This mutation was backcrossed onto the NOD/ShiJic strain at CIEA for at least eight generations. (taconic.com)
  • The Il2rg targeted mutation was developed by Dr. Kazuo Sugamura of Tohoku University by targeting the gene in ES cells derived from a 129 strain. (taconic.com)
Rabbits2
  • Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally occurring albino animals exist in the wild, e.g. (wikipedia.org)
  • To avoid charges, cancellations for timed mated rats, mice, guinea pigs, and hamsters must be received one week prior to mating date, however, cancelled orders for timed mated rabbits will be charged at full price regardless of the amount of notice supplied. (inotivco.com)
Loci3
  • What Haldane receive was research to own coupling ranging from mutations during the albino (c) and you may green-eyed dilution (p) loci, and therefore we have now discover to lie 15 cM aside into Chr eight. (kenyan.bible)
  • Earliest, studies was only you'll which have loci present because the option alleles during the the 2 inbred parental stresses accustomed form for every RI set. (kenyan.bible)
  • Just a few particularly loci - mostly those who apply at layer colour - have been polymorphic among additional inbred strains. (kenyan.bible)
Laboratory animals1
  • However, compared to traditional laboratory animals like rats, very little is known about its behavior, either in the wild or in a laboratory setting. (researchgate.net)
Behavioral3
  • 5-7 spike-and-wave complex associated with behavioral absence-like seizure starts at about 14 weeks of age in tm / tm rats and at about 26 weeks of age in tm /+ rats (Serikawa,1987 and Higashiguchi, 1991). (kyoto-u.ac.jp)
  • Castagné V, Moser P, Roux S, Porsolt RD. Rodent models of depression: forced swim and tail suspension behavioral despair tests in rats and mice. (ijbcp.com)
  • With collaborators, we are exploring the behavioral and anatomic consequences of induced malformations by testing rats in various auditory discrimination paradigms and subsequent examination of their brains. (dyslexialab.net)
SsNHsd1
  • The polymorphic rate of our 357 SSLP makers is 83% against BN/SsNHsd strain and 73% against LE/Stm strain. (nig.ac.jp)
Estrus2
  • Envigo uses an impedance meter for determining the stage of estrus in rats. (inotivco.com)
  • Females 8 or more weeks of age show 4-day-estrous-cycle under certain conditions (see "other information" of "a basic manual as for breeding rats) Since the signs of estrus are clear and the ovulation time is concentrated in the midnight, it is quite useful for experiments on reproduction. (or.jp)
Experiments2
  • This strain is used for experiments on the etiology of metabolic syndrome, non-alcoholic steatohepatitis, and evaluate foods and medicines. (or.jp)
  • Breeding Experiments with Rats The American Naturalist 43: 182-185. (esp.org)
Toxicity1
  • In 1934, DeEds presented first evidence that much higher doses of fluoride are required to produce similar signs of toxicity in rats when compared to humans. (poisonfluoride.com)
Proteins1
  • These potential health benefits are attributed to the presence of a plethora of bioactive zoochemicals, including lactoferrin, immunoglobulins and peptidoglycan recognition protein 11 , however, other functional components could be derived from camel milk proteins via fermentation using probiotic strains 12 . (scialert.net)
Mutant2
  • CNS Pathology in the neurological mutant rats zitter, tremor and zitter-tremor double mutant (spontaneously epileptic rat, SER). (kyoto-u.ac.jp)
  • Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system. (kyoto-u.ac.jp)
Congenital1
  • Examples of albino laboratory mammals Albinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and reddish pink or blue eyes. (wikipedia.org)
Cells derived1
  • Genetic manipulation of the mouse genome has been customarily performed using ES cells derived from the agouti 129-inbred strain of mouse. (umassmed.edu)
Albinism2
  • It is a common misconception that all albino animals have characteristic pink or red eyes (resulting from the lack of pigment in the iris allowing the blood vessels of the retina to be visible), however this is not the case for some forms of albinism. (wikipedia.org)
  • Type I oculocutaneous albinism (OCA1a) is the form most commonly recognised as 'albino' as this results in a complete absence of melanin in the skin, hair/fur/feathers, and pink pupils, however this has led many to assume that all albinos are pure white with pink pupils, which is not the case. (wikipedia.org)
Colony3
  • Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay. (kyoto-u.ac.jp)
  • The strain was developed by Shisa et al at the Saitama Cancer Center Research Institute from a closed colony of Long-Evans (University of Chicago). (nig.ac.jp)
  • It is maintained in a closed colony of the circulation mating method, which is designed to delay inbreeding as much as possible. (or.jp)
Spontaneous2
  • A new model of petit mal epilepsy: spontaneous spike and wave discharges in tremor rats. (kyoto-u.ac.jp)
  • This strain is a spontaneous type 2 diabetes model animal. (or.jp)
Examples1
  • Once the talked about in more detail when you look at the Section nine.2, a set of RI stresses will bring a collection of examples inside the and this recombination incidents ranging from homologs of one or two various other inbred stresses try managed into the perspective of the latest inbred stresses. (kenyan.bible)
Breeding1
  • Pure Strains as Artifacts of Breeding The American Naturalist 43: 241-242. (esp.org)
Genetic4
  • Advances on Genetic Rat Models of Epilepsy. (kyoto-u.ac.jp)
  • Hcn1 is a tremorgenic genetic component in a rat model of essential tremor. (kyoto-u.ac.jp)
  • Embryo transfer (ET) is an essential reproductive technology for the production of new animal strains and maintenance of genetic resources. (nature.com)
  • Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice. (ijbcp.com)
Humans2
  • Long-Evans rats are used in fields such as ethology, psychology, and neuroscience that are supposed to be extrapolated to humans. (or.jp)
  • When the use of laboratory animal is obligatory, the most appropriate specie, breed, and strain with the closest homology to humans must be chosen. (ommegaonline.org)
Incidence1
  • L. C. Dunn breeds Strain 129, which later proves to have a high incidence of testicular cancer. (jax.org)
Mouse1
  • Antidepressant-like effects of nicotine and mecamylamine in the mouse forced swim and tail suspension tests: role of strain, test and sex. (ijbcp.com)
Il2rg1
  • This strain shows severe combined immunodeficiency caused by a 7-bp deletion in the exon 2 of Il2rg gene. (kyoto-u.ac.jp)
Metabolic1
Reduction1
  • This study was conducted to investigate the chemopreventive potential of camel ( Camelus dromedarius ) and bovine milk as well as the impact of fermenting these milks with Lactobacillus acidophilus and Streptococcus thermophilus against early colon carcinogenesis as measured by the reduction of aberrant crypt foci (ACF) in azoxymethane (AOM)-treated Fischer 344 rats. (scialert.net)
Center1
  • BAC clones are available from RIKEN BioResource Center by NBRP Rat Genome Information Upgrading Program ( Kyoto University , RIKEN Genomic Sciences Center, and Comparative Genomics Laboratory, National Institute of Genetics ) in Japan. (nig.ac.jp)
Groups2
  • At termination, all rats were euthanized, colons were harvested and the ACF counts were determined for all tested groups. (scialert.net)
  • Inbred strains of albino mice were divided into four groups and were fed with CD, HFD, GM+HFD and GM+CD. (bvsalud.org)
Average1
  • for example, it has been suggested that albino alligators have an average survival span of only 24 hours due to the lack of protection from UV radiation and their lack of camouflage to avoid predators. (wikipedia.org)
Diet1
  • Bacterial strains including Bacteroides gallinarum (MT152630), Ruminococcus bromii (MT152631), Lactobacillus acidophilus (MT152632), Parabacteroides gordonii (MT152633), Prevotella copri (MT152634) and Lactobacillus gasseri (MT152635) were isolated from mice treated with GM+modified diet (HFD/CD) compared to strains Akkermansia muciniphila (MT152625), Bacteriodes sp. (bvsalud.org)
Basis1
  • Isolated bacterial strains were identified on the basis of morphological and biochemical tests. (bvsalud.org)
Method1
  • We developed a method, named Easy-ET, to induce pseudopregnancy in female rats by artificial stimulation using sonic vibration instead of mating with vasectomized males. (nature.com)
Condition1
  • Individuals with the condition are referred to as albinos. (wikipedia.org)