• 7. Drugs that exert their influence during any phase of the cell cycle are called Cell cycle nonspecific (CCNS) drugs and include Alkylating agents, hormones and anti-tumor antibiotics. (studylib.net)
  • 1. According to the structure and function can be divided into the alkylating agent, anti metabolites, Antibiotics , animal and plant effective components, hormones etc. (g-housemedicines.com)
  • It is a purine nucleoside antimetabolite . (bionity.com)
  • Until recently, the treatment of cancer has been largely focused on the development of therapeutic agents or techniques that kill cancer cells. (justia.com)
  • Future pre-clinical and clinical studies are urgently needed to evaluate the safety and efficacy of Boswellia sacra essential oil as a therapeutic agent for treating breast cancer. (biomedcentral.com)
  • Smoking Smoking Willful or deliberate act of inhaling and exhaling smoke from burning substances or agents held by hand. (lecturio.com)
  • Drugs used to manage connective tissue disease (CTD) associated with interstitial lung disease (ILD) (CTD-ILD) include nintedanib, corticosteroids, and antineoplastic agents. (medscape.com)
  • In popular usage, it usually refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a standardized treatment regimen . (wikidoc.org)
  • In 2019, Sun Pharma launched ready-to-infuse INFUGEM (gemcitabine in sodium chloride injection) in the U.S. INFUGEM, the first chemotherapy product that comes in a premixed, ready-to-infuse formulation, was approved by the U.S. Food and Drug Administration (FDA) in July 2018, in combination with other drugs, for the treatment of breast, ovarian, non-small cell lung cancers, and as a single agent to treat pancreatic cancer. (transparencymarketresearch.com)
  • Drugs that exert their influence during a specific phase(s) of the cell cycle are called Cell cycle -specific (CCS) drugs and include antimetabolites, some alkylating agents and vinca alkaloids. (studylib.net)
  • Product categories of Antineoplastic , we are specialized manufacturers from China, Natural Antineoplastic , Antineoplastic Drugs suppliers/factory, wholesale high-quality products of Antineoplastic Agentsu R & D and manufacturing, we have the perfect after-sales service and technical support. (g-housemedicines.com)
  • Because embryonic tissues grow rapidly and have a high DNA turnover rate, they resemble cancer tissues and are thus very vulnerable to antineoplastic drugs. (msdmanuals.com)
  • Prior therapy with alkylating agents and fludarabine. (pocketdrugguide.com)
  • Patients relapsed after or were refractory to alkylating agents and failed to achieve a PR with their last fludarabine-based therapy. (pocketdrugguide.com)
  • 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key 1 Define the following terms: 1. (studylib.net)
  • 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key excretion of cellular breakdown products and to reduce the risk of hemorrhagic cystitis. (studylib.net)
  • 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key 3 greater, brimmed hats, and lightweight, long-sleeved shirts). (studylib.net)
  • Cell cycle-specific with activity in the S-phase as single agent and has for many years been combined with biochemical modulator leucovorin.Has activity as single agent that inhibits DNA replication and transcription. (medscape.com)
  • Hydroxyurea, an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. (targetmol.com)
  • Classic antimetabolite anticancer drug with chemical structure similar to endogenous intermediates or building blocks of DNA or RNA synthesis. (medscape.com)
  • 4. Pharmaceuticals used to destroy cancer cells are called anticancer, chemotherapeutic, antineoplastic, or cytotoxic 5. (studylib.net)
  • Another method of the invention comprises administering a cell growth inhibitor to the subject and administering to the subject a chemotherapy agent. (justia.com)
  • Antineoplastic PEG-rhG-CSF Injection for the patients of non-myeloablative malignancy with the treatment of antineoplastic, when may have clinic significance of febrile neutrophilic reduce myelosuppression, using this product to reduce the incidence rate of infection caused by febrile neutropenia. (g-housemedicines.com)
  • Some chemotherapeutic agents with an antibiotic effect can alter the composition of the microbiota (bacterial set or bacterial flora) of the milk and the concentration of some of its components (Urbaniak 2014). (e-lactancia.org)
  • With succeeding generations of tumor cells, differentiation is typically lost, growth becomes less regulated, and tumors become less responsive to most chemotherapeutic agents. (wikidoc.org)
  • The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. (justia.com)
  • Because chemotherapy affects cell division, both normal and cancerous cells are susceptible to the cytotoxic effects of chemotherapeutic agents. (justia.com)
  • It also has severe limitations on the dosage of chemotherapeutic agents that can be administered to a patient, thus, limiting the effective range of chemotherapy. (justia.com)
  • The present invention provides a novel approach to cancer therapy by providing a method to differentially enhance the resistance of normal cells to chemotherapeutic agents, thereby, improving the effectiveness of chemotherapeutic agents in killing cancerous cells. (justia.com)
  • By making normal cells more resistant to chemotherapeutic agents, a patient's tolerance for cytotoxicity is improved, which, in turn, also improves the effectiveness of chemotherapy. (justia.com)
  • Cisplatin is a platinum-containing compound that exerts an antineoplastic effect by covalently binding to DNA, with preferential binding to N-7 position of guanine and adenosine. (medscape.com)
  • These agents alkylate DNA bases, thereby producing "cross-links" that covalently link the two DNA strands and prevent cell replication. (pocketdrugguide.com)
  • An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. (targetmol.com)
  • This is a phase 2/3, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or in combination in participants with unresectable, advanced or metastatic NSCLC determined to harbor oncogenic somatic mutations or positive by tumor mutational burden (TMB) assay as identified by two blood-based next-generation sequencing (NGS) circulating tumor DNA (ctDNA) assays. (clinicaltrials.gov)
  • Ataxia telangiectasia and Rad3-related protein (ATR), the apical kinase of the intra-S-phase DNA damage response, plays a central role in safeguarding cells from replication stress and can therefore limit the efficacy of antimetabolite drug therapies. (nih.gov)
  • Multidisciplinary team, standards of care, optimal therapies, and novel agents in the care of cancer patients in Sub-Saharan Africa. (intercancer.com)
  • Taxanes alone or in combination with other agents have demonstrated efficacy in the treatment of hormone-refractory prostate cancer. (medscape.com)
  • High unmet needs in this area and poor efficacy of current treatments in pancreatic cancer, which are mostly chemotherapies, have prompted developers to explore improved versions of branded gemcitabine agents. (transparencymarketresearch.com)
  • The antimetabolite gemcitabine remains part of the standard of care but shows very limited antitumor efficacy. (nih.gov)
  • Other uses of cytostatic chemotherapy agents (including the ones mentioned below) are the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and the suppression of transplant rejections (see immunosuppression and DMARDs ). (wikidoc.org)
  • The use of two or more chemotherapy agents is referred to as combination therapy 6. (studylib.net)
  • Keratolytic agents like TCA and bichloracetic acid (BCA) are extremely powerful keratolytic agents that rapidly penetrate and chemically cauterize skin, keratin, and other tissues. (medscape.com)
  • Ox)aliplatin - a platinum-based alkylating antineoplastic agent. (wikipedia.org)
  • Premenopausal and postmenopausal patients all can use Antineoplastic Tamoxifen Tablets, and the effect is well for the postmenopausal and people over the age of 60 than premenopausal and young patients. (g-housemedicines.com)
  • Antineoplastic Tamoxifen Tablets 20mg used in the treatment of advanced breast cancer and ovarian cancer. (g-housemedicines.com)
  • This agent is indicated for intralesional treatment of refractory or recurring external condyloma acuminatum and is particularly useful for patients who have not responded satisfactorily to other treatment modalities (eg, podophyllin, surgical excision, laser therapy, or cryotherapy). (medscape.com)
  • Prior therapy with alkylating agents either alone or in combination. (pocketdrugguide.com)
  • As an alkylating agent, the mechanism of action of the active metabolites may involve cross-linking of deoxyribonucleic acid (DNA), which may interfere with the growth of normal and neoplastic cells. (medscape.com)
  • Cyclophosphamide is an alkylating agent. (pocketdrugguide.com)
  • Cyclophosphamide/Alkylating Agent Concept/Action/Use Assessment Immunity CCNS Damage cell's DNA preventing reproduction of cancer cells. (studylib.net)
  • Also, this agent has an additional immunosuppressive effect. (medscape.com)
  • An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. (lookformedical.com)
  • An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. (lookformedical.com)
  • Pemetrexed is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesotheli. (targetmol.com)
  • In that sense, the first modern chemotherapeutic agent was Paul Ehrlich 's arsphenamine , an arsenic compound discovered in 1909 and used to treat syphilis . (wikidoc.org)
  • An antineoplastic compound which also has antimetabolite action. (lookformedical.com)
  • From cell surface to nucleus: CCRL2 regulates response to hypomethylating agents in myelodysplastic syndromes. (uchicago.edu)
  • It was reasoned that an agent that damaged the rapidly growing white blood cells might have a similar effect on cancer. (wikidoc.org)
  • Antimetabolites that are useful in cancer chemotherapy. (lookformedical.com)
  • In another aspect, the invention features methods of contacting a cancer cell with a chemotherapy agent and methods of increasing resistance of a non-cancer cell to a chemotherapy agent. (justia.com)
  • An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities. (medicalterminologydb.com)
  • Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid. (targetmol.com)
  • In clonogenic assays, the combination abrogated survival at concentrations for which single agents had minor effects. (nih.gov)
  • Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. (targetmol.com)
  • These agents inhibit key factors involved in immune reactions. (medscape.com)
  • Agents that suppress immune function by one of several mechanisms of action. (lookformedical.com)