Agency s drug compounding. Medical search. Frequent questions

Patients intending to use semaglutide should have a prescription from a licensed healthcare provider and only obtain medicines from state-licensed pharmacies or outsourcing facilities registered with FDA, the agency said. (upi.com)
Lembo said 91 percent of the compound drug claims to the state plan came from out-of-state compound pharmacies, and he reiterated that the drugs themselves also are "largely unregulated" by the U.S. Food and Drug Administration. (ctnewsjunkie.com)
Compounding pharmacies must register with the FDA, but that is a separate process from the FDA approval process. (medscape.com)
Through our Fraud.org website and NCL's partnership with the Alliance for Safe Online Pharmacies (ASOP Global) , NCL is continuing to educate consumers on the dangers of counterfeit drugs and the steps they can take to protect themselves when buying drugs online. (nclnet.org)
And 'if pharmacists are to perform sterile compounding, hospitals and pharmacies must not balk at spending the required money to supply the pharmacy with the needed equipment. (drugtopics.com)
If compounding pharmacies such as CAPS are offering a sterile compounding service, their standards must meet, if not exceed, USP chapter 797 standards set back in 2004,' Gallagher concluded. (drugtopics.com)
The consumer watchdog group Public Citizen is calling on the FDA to add the active pharmaceutical ingredient in Belviq to an official list of banned or withdrawn medications, to prevent the recalled weight loss drug from being used by compounding pharmacies. (aboutlawsuits.com)
The group indicates the list is consistently out-of-date, often by years, which means the banned drugs can still legally be made by physicians and compounding pharmacies for special orders, even though the agency has recalled Belviq from the market due to the unreasonable risk that users may develop cancer. (aboutlawsuits.com)
Two Democratic lawmakers on Tuesday called for stricter federal oversight of compounding pharmacies in the wake of a deadly meningitis outbreak linked to contaminated injections made by a Massachusetts specialty pharmacy. (wbur.org)
Compounding pharmacies traditionally supply products that are not available commercially, based on an individual doctor's prescription. (wbur.org)
But some pharmacies have grown into larger businesses, operating across state lines and supplying drugs to thousands of hospitals, clinics and physicians. (wbur.org)
Compounding pharmacies have long operated in a legal gray area between state and federal laws. (wbur.org)
Despite that history, Markey said Tuesday the FDA should have authority to bar compounding pharmacies from using ingredients that haven't been cleared by the agency. (wbur.org)
Unfortunately, compounding pharmacies are a 19th century service operating in a 21st century industry, and we need to update and strengthen the rules that govern these operations so that patients can safely benefit from the unique service they offer," said Markey, who sits on the House Energy and Commerce Committee, which oversees the FDA. (wbur.org)
Compounding pharmacies technically fall under the jurisdiction of state pharmacy boards, which also regulate traditional pharmacies, though experts say these organizations often lack the resources and expertise to inspect the more than 7,500 compounding pharmacies operating in the U.S. (wbur.org)
In the 1990s, FDA regulators began to more closely scrutinize the industry, as some compounding pharmacies grew into larger operations that resembled small pharmaceutical companies. (wbur.org)
Specifically, the law banned compounding pharmacies from advertising their products. (wbur.org)
But recent congressional legislation (the Drug Quality and Security Act, or DQSA) gave the FDA increased authority over compounding pharmacies, and the agency has responded by abusing its new powers to achieve its old agenda. (anh-usa.org)
With all of these issues combined, it will increasingly difficult for compounding pharmacies to stay in business. (anh-usa.org)
But Franck's argued that the traditional, state-licensed practice of compounding commercially unavailable veterinary medications from bulk ingredients is a legal practice followed by licensed pharmacies across the nation. (dvm360.com)
Novo Nordisk has commenced the filing of legal actions in the US against certain medical spas, weight loss or wellness clinics, and compounding pharmacies to cease and desist from false advertising, trademark infringement and/or unlawful sales of non-FDA approved compounded products claiming to contain semaglutide. (novonordisk-us.com)
The warning comes as many people have reported turning to compounding pharmacies to get cheaper doses of semaglutide, the active ingredient in both Ozempic and Wegovy. (abc7chicago.com)
The FDA also said that some compounding pharmacies claiming to sell semaglutide might instead be selling other formulations of the chemical, like semaglutide sodium and semaglutide acetate. (abc7chicago.com)
Wyeth, the maker of Premarin and Prempro, filed a "Citizens Complaint" with the FDA on October 16, 2005, requesting that the FDA effectively prohibit compounding pharmacies from providing bio-identical hormones to their patients. (newmediaexplorer.org)
Wyeth wants to force women to take their counterfeit hormones by eliminating the competition from bio-identical hormones prepared by compounding pharmacies. (newmediaexplorer.org)
The FDA collects no drug user fees from compounding pharmacies because they are regulated by the states, not the federal government. (newmediaexplorer.org)
So the FDA wants to eliminate compounding pharmacies as well. (newmediaexplorer.org)

Today, the FDA is also announcing that it intends to move cesium chloride to category 2 under the FDA's interim policy on compounding with bulk drug substances under section 503A. (fda.gov)
Under the interim policy, a bulk drug substance placed in category 2 raises significant safety risks in compounding and is not subject to the FDA's enforcement policy on compounding with the bulk drug substance while the FDA is formally evaluating that substance for use in compounding through the rulemaking process. (fda.gov)
Compounders must follow quality manufacturing practices to ensure consumers are not exposed to potentially harmful drugs," said Donald Ashley, director of the Office of Compliance in the FDA's Center for Drug Evaluation and Research. (beckershospitalreview.com)
The groups urged the committees not to limit FDA's ability to enforce federal drug compounding law, including requirements on prescriptions and quality standards. (pewtrusts.org)
In December 2013, FDA rolled out Guidance for Industry No. 213 asking drug sponsors to align with GFI No. 209, FDA's judicious use principles for antimicrobials. (avma.org)
Franck's voluntarily stopped compounding veterinary drugs in May 2010 following the FDA's filing. (dvm360.com)

We will determine the extent to which hospitals obtain compounded sterile preparations from compounders, including outsourcing facilities that have registered with the Food and Drug Administration. (hhs.gov)
We will also determine the extent to which compounders that produce compounded sterile preparations without a patient-specific prescription have registered with the Food and Drug Administration. (hhs.gov)
The FDA has ordered Pharm D Solutions, a Texas compounding pharmacy, to cease all sterile compounding operations and distribution. (beckershospitalreview.com)
The order prohibits the compounder from making any sterile drugs until it completes corrective actions. (beckershospitalreview.com)
ASHP went on to say that 'the fact that CAPS is an FDA-registered facility suggests that a reexamination of the regulatory framework (including rigor and frequency of inspections) of commercially large-scale operations that compound sterile products for hospitals is in order. (drugtopics.com)
Sterile compounding is not new to pharmacy, but it is a skill that requires better methods, better techniques, and much greater oversight in order to produce safe and effective products,' noted Gallagher. (drugtopics.com)
CHA raises concerns about the proposed policy that would require compounded drug products to be administered or discarded within 24 hours of transfer out of the pharmacy, which does not align with the beyond use dates for sterile compounded drug products established by the United States Pharmacopeia. (calhospital.org)

Settings in which a compounded product may be needed include those in which patients are unable to swallow a pill, as well as for the treatment of children and of pain patients who require a medication dose different from what is commercially available. (medscape.com)
As the kits became commercially available in the 1970s, numerous chemists strongly warned against police using them to directly determine whether evidence contained a drug. (propublica.org)

On June 5, following-up to NCL's October 2016 comments on the FDA draft guidances for industry on compounded drug products, NCL sent a letter to the FDA and published an op-ed in the Huffington Post urging the FDA to continue to advance its December 2016 compounding guidance in the interest of patient safety. (nclnet.org)
In the letter , CHA applauds the agency for revising its earlier 2016 draft guidance to eliminate the previously proposed policy that would have established a one-mile radius requirement as criteria for medication distribution by a hospital or health system. (calhospital.org)
But compared to the six drugs China approved in 2016, the improvement in approval speed is notable. (mercatus.org)
In July 2016, the Drug Enforcement Administration (DEA) issued a nationwide report indicating that hundreds of thousands of counterfeit pills have been entering the U.S. drug market since 2014, some containing deadly amounts of fentanyl and fentanyl analogs [2]. (cdc.gov)
From 2014 to 2015 the number of drug submissions testing positive for acetyl fentanyl increased substantially, rising from 463 in 2014 to 1,870 in 2015[9,10,11], and in 2016, NFLIS reported increasing drug submissions testing positive for furanyl fentanyl (244 drug submissions from January to July 2016) [9]. (cdc.gov)
from October 2014 to September 2015, federal, state, and local law enforcement agencies seized a total of 167.7 kilograms of fentanyl, and through June, 2016, they seized 363.8 kilograms of fentanyl [9]. (cdc.gov)

Today, the FDA is issuing an alert warning about a bulk drug substance (active pharmaceutical ingredient) used in compounding that carries significant safety risks for patients. (fda.gov)
Jim Hrncir, RPH, Las Colinas Pharmacy (503A compounding pharmacy), said during the session that it is possible to get much higher concentrations of the active pharmaceutical ingredient in a smaller pill or a smaller amount of liquid. (medscape.com)
Although it is usually possible to determine where a compounding pharmacy obtained a particular active pharmaceutical ingredient, it can be difficult to trace an ingredient further back in the chain. (medscape.com)

Patients and their doctors should also understand that the FDA does not review compounded drugs for safety, effectiveness or quality. (upi.com)
Patients and health care professionals should understand that the agency does not review compounded versions of these drugs for safety, effectiveness, or quality. (novonordisk-us.com)

Our aim is to be responsive to the medical needs of patients who require compounded medicines, while making sure that these products are compounded under appropriate standards. (fda.gov)

CHA has submitted comments to the Food and Drug Administration (FDA) on its revised draft guidance on hospital and health system compounding under Section 503A of the Federal Food, Drug, and Cosmetic Act. (calhospital.org)

As part of its ongoing implementation of the Drug Quality and Security Act and to advance the goals of its 2018 Compounding Policy Priorities Plan , the U.S. Food and Drug Administration is announcing several actions to protect public health related to the compounding of human drug products. (fda.gov)
The meeting follows a September 26, 2018, US Food and Drug Administration (FDA) announcement that the NASEM would conduct two studies related to compounded drugs in collaboration with the University of Maryland and Johns Hopkins University Centers for Regulatory Science and Innovation. (medscape.com)
In the first nine months of 2018, the China Food and Drug Administration (CFDA) approved no fewer than 37 new drugs, the vast majority of which were produced by foreign manufacturers. (mercatus.org)
In 2018, the average drug approval took just over three years. (mercatus.org)

There can be tin metal as well as inorganic and organic tin compounds in the air, water, and soil near places where they are naturally present in the rocks, mined, manufactured, or used. (cdc.gov)
Surface fungicides, which keep harmful fungi from penetrating the tissues of a plant, include inorganic and organic compounds. (infoplease.com)

Today, the FDA issued a compounding risk alert to warn health care providers, compounders and patients of the dangers of using the bulk drug substance cesium chloride. (fda.gov)
Compounders can make a version of a drug if the medication is in shortage and they meet requirements of the Federal Food, Drug and Cosmetic (FD&C) Act. (upi.com)
The FDA is cautioning drug compounders and manufacturers about a potential risk of chemical contamination stemming from Chinese shipments. (pharmacytimes.com)
The agency also stressed that compounders should know where their drug ingredients come from, and if they have questions, they should contact the foreign manufacturer for information. (pharmacytimes.com)
Under new rules proposed by the FDA, there will be an approved list of "bulk ingredients" (drugs) the FDA will allow to be sold by compounders in outsourcing facilities. (anh-usa.org)

Large-scale facilities that compound without a patient-specific prescription are regulated under section 503B of the Food, Drug and Cosmetic Act and referred to as outsourcing facilities. (hhs.gov)
Today, the FDA is announcing two new research collaborations to support its goal of developing the list of bulk drug substances that can be compounded under section 503B and to help inform public understanding of the use of bulk drug substances in compounding. (fda.gov)

The compound has a mild psychoactive response, slightly more so than CBD but much less than THC. (forbes.com)
At the same time, the agency approved psilocybin, the primary psychoactive compound found in magic mushrooms, as a therapy for treatment-resistant depression. (forbes.com)
THC is the psychoactive compound in cannabis. (rtmagazine.com)

In order to address these public health burdens compounded by the relationship between ACEs and substance use, in collaboration with the National Association of City and County Health Officials, the Centers for Disease Control and Prevention and the High Intensity Drug Trafficking Agency have funded The Martinsburg Initiative since 2017. (cdc.gov)
Progress against malaria has stalled in these high-burden African countries since 2017 due to factors including humanitarian crises, low access to and insufficient quality of health services, climate change, gender-related barriers, biological threats such as insecticide and drug resistance and global economic crises. (who.int)

Compounded medications are not FDA-approved. (upi.com)
Compounding medications, a skill that has been passed down through apprenticeships of the past and taught in modern pharmacy schools, has been the responsibility of pharmacists for as long as the profession has existed,' asserted Michael L. Gallagher, M.S., R.Ph. (drugtopics.com)
Clinical trials also showed the drug does not affect the efficacy of HIV medications. (wraltechwire.com)
The suit, filed in U.S. District Court for the Middle District of Florida, claimed that animal medications compounded from bulk ingredients could not be distributed without an FDA-approved new animal drug application. (dvm360.com)

The FDA recently released a guidance on INDs, or Investigational New Drug (IND) applications-the starting point for all FDA-approved drugs. (anh-usa.org)
This overreaching guidance requires companies to start a burdensome and expensive drug approval process if a nutrient is to be studied for potential health claims-even if the supplement won't be marketed as a drug. (anh-usa.org)
For seven years, IACP and members of Congress continued to send a clear and simple message to the FDA-fix the Veterinary Compounding Compliance Policy Guidance document. (dvm360.com)
To provide practical guidance for handling situations where relatively unstudied compounds with limited or no toxicity data are encountered, recommendations are provided on ADI values that correspond to three categories of compounds: (1) com- pounds that are likely to be carcinogenic, (2) compounds that are likely to be potent or highly toxic, and (3) compounds that are not likely to be potent, highly toxic or carcinogenic. (cdc.gov)
1996, 1997b), no guidance is provided for determining ogenic, (2) compounds that are likely to be potent or acceptable levels for genotoxic impurities. (cdc.gov)

Some of the dioxins and dioxin-like compounds have been classified by the International Agency for Research on Cancer (IARC) as known human carcinogens, others as probable human carcinogens, while others are not classifiable as to their carcinogenicity Footnote 1 in humans. (canada.ca)
The International Agency for Research on Cancer (IARC) is pleased to announce that the IARC Monographs volume on some aromatic amines and related compounds is now available online. (who.int)
Some organic solvents, resin monomers and related compounds, pigments and occupational exposures in paint manufacture and painting / this publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans which met in Lyon, 18-25 October 1988. (who.int)

International Agency for Research on Cancer. (who.int)

The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. (cdc.gov)
They must be registered with the Environmental Protection Agency and must conform to specifications. (infoplease.com)
To assess the extent of illness from ingestion of lindane, CDC, with assistance from the U.S. Environmental Protection Agency, Food and Drug Administration (FDA), and state health departments, collected case reports and analyzed data from the Sentinel Event Notification System for Occupational Risks-Pesticides (SENSOR-Pesticides) program and the Toxic Exposure Surveillance System (TESS). (cdc.gov)

CBD, an abbreviation of cannabidiol, a non-intoxicating compound found in cannabis and hemp plants, is going viral across the globe. (forbes.com)
However, CBD is just one of the hundreds of compounds inherent to the cannabis plant. (forbes.com)
Even though THC and CBD are garnering all the buzz, there are myriad other cannabis compounds which can help alleviate a plethora of symptoms -including CBN. (forbes.com)
Within a month, the Drug Enforcement Administration is expected to release a much-anticipated decision that could alter cannabis' ranking in the hierarchy of controlled substances - a formal listing that affects everything from medical research to taxing policy. (mapinc.org)
WHAT RESCHEDULING WOULD DO For the medical marijuana community, even reclassifying cannabis as a Schedule II drug would offer some vindication. (mapinc.org)
And, while it is extracted from cannabis plants, CBD is not the compound that delivers the "high" associated with marijuana. (overdriveonline.com)

Unlike drugs manufactured by large pharmaceutical companies, compounded drugs have never been reviewed for safety and effectiveness by FDA. (wbur.org)

This provides an uninterrupted stream of visual data over the lifetime of the reporter cell as it interacts and reacts to compound exposure at both its pre- and post-biotransformed states. (inknowvation.com)
This public health statement tells you about tin and tin compounds and the effects of exposure to them. (cdc.gov)
Organic tin compounds can be degraded (by exposure to sunlight and by bacteria) into inorganic tin compounds. (cdc.gov)
The World Health Organization (WHO) considers dioxins and dioxin-like compounds a health concern on a global scale, and has recently re-iterated the need to reduce emissions of, and human exposure to, these persistent organic pollutants. (canada.ca)
Approximately 90% of a person's exposure to dioxins and dioxin-like compounds occurs through the diet, particularly through the consumption of high-fat animal tissues and dairy products. (canada.ca)
The levels of dioxins and dioxin-like compounds observed in this survey are unlikely to contribute significantly to the overall exposure of Canadians to these contaminants, and are not likely to be of human health concern. (canada.ca)
Its discoverer, a Swiss chemist named Albert Hoffman, began to experience hallucinations after an inadvertent percutaneous exposure to the drug. (medscape.com)
Exposure to these chemicals may occur variously through cigarette smoking, in industrial settings including manufacture of plastics, rubber, pharmaceutical drugs, and dyes and pigments used in consumer products such as paper and textiles, and via tattoo inks. (who.int)

An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine (NASEM) held its second information gathering session on compounded bioidentical hormone replacement therapy (BHRT) on May 6. (medscape.com)
The Committee on Clinical Utility of Treating Patients With Compounded "Bioidentical Hormone Replacement Therapy" is examining issues such as the active and inactive ingredients in these products, dosage forms, administration routes, and strengths. (medscape.com)
Compounded bioidentical [hormone therapy] presents safety concerns such as minimal government regulation and monitoring, overdosing or underdosing, presence of impurities or lack of sterility, lack of scientific efficacy and safety data, and lack of a label outlining risks. (medscape.com)
This is very good news for our campaign to save estriol, other bioidentical hormones, and many other compounded supplements and drugs from being regulated right out of existence. (anh-usa.org)
The FDA has been trying to eliminate bioidentical hormones and other critical compounded supplements-many of them only available as compounded supplements-for many, many years. (anh-usa.org)
In addition to bioidentical hormones, delivery systems such as time release capsules have also been nominated to the "difficult to compound" list-threatening, for example, time-release thyroid drugs. (anh-usa.org)

These categories address all tion to cleaning validation and the resolution of atypical types of toxicological endpoints, including carcinogenic- extraneous matter investigations for relatively unstudied ity, immunotoxicity, neurotoxicity, and developmental compounds in APIs and finished pharmaceutical prod- toxicity. (cdc.gov)

Representatives Rosa DeLauro and Edward Markey said in separate statements that they will draft legislation to give the Food and Drug Administration more authority to police the safety of custom-mixed medicines, known as compounded drugs. (wbur.org)
PLAINSBORO, N.J. , June 20, 2023 /PRNewswire/ -- Novo Nordisk announced today that it is taking multiple actions to protect US patients from the unlawful marketing and sales of non-FDA approved counterfeit and compounded semaglutide products claiming to contain semaglutide, while reinforcing the responsible use of Novo Nordisk's FDA-approved medicines. (novonordisk-us.com)
Further, the practice of selling compounded semaglutide medicines under Novo Nordisk trade names is unlawful and will not be tolerated. (novonordisk-us.com)
WHO and other humanitarian partners demand all parties to the conflict in Sudan respect the safety and neutrality of health workers, patients, and health facilities and ensure a safe path for supplies to arrive in hospitals which are reporting severe shortages of trauma supplies, medicines, and anesthesia drugs. (who.int)

An incident that tied a compounded drug solution to three deaths and eight acute illnesses has captured the attention of both the media and the many pharmacists who regularly compound critical care drug products for hospital use. (drugtopics.com)
How pharmacists feel about the regulation-or lack thereof-of compounding is another matter. (drugtopics.com)
instead to a statement released by the International Academy of Compounding Pharmacists (IACP). (dvm360.com)

This is basically a shadow industry with little regulatory oversight because many compounded drugs technically fall under unapproved drugs and the FDA simply doesn't have the manpower to be everywhere at once,' noted Sasich. (drugtopics.com)
FDA believes it is important to include veterinary oversight in the use of medically important antimicrobial drugs to ensure their appropriate and judicious use. (avma.org)
Compounded drugs are not mentioned in the landmark 1938 law that gave the FDA authority to regulate virtually all drugs sold in the U.S. For more than 50 years, the FDA exercised little oversight over the space. (wbur.org)
In 1997, Congress passed a law bringing compounded drugs under FDA oversight, requiring that they meet certain standards for production, labeling and advertising. (wbur.org)

Patients taking semaglutide for Type 2 diabetes or weight loss should be careful about where they're getting the medication, the U.S. Food and Drug Administration warned Tuesday. (upi.com)
The agency said it has expressed concern to the National Association of Boards of Pharmacy about the use of salt forms of semaglutide in these products. (upi.com)
FDA has received adverse event reports after patients used compounded semaglutide. (novonordisk-us.com)
Patients prescribed FDA-approved semaglutide injectable products, marketed under the brand names Ozempic ® and Wegovy ® , should be vigilant in checking their medicine to ensure they are taking an authentic, Novo Nordisk produced version of the authorized drug and injection device. (novonordisk-us.com)
In addition to launching semaglutide.com as a resource hub to the public, Novo Nordisk has disseminated information directly to healthcare providers and is working with other stakeholders to ensure patients are aware of the dangers of compounded or counterfeit products claiming to contain semaglutide. (novonordisk-us.com)
The FDA said it's received reports of adverse events after people took semaglutide that came from a compounding pharmacy. (abc7chicago.com)

In May, NCL issued a statement expressing concern that pending prescription drug importation proposals will open the U.S. market to a flood of counterfeit and/or substandard drugs, putting patient health and safety at risk. (nclnet.org)

We continue to implement the compounding provisions of federal law and advance a modern framework for the development of compounded drugs," said FDA Commissioner Scott Gottlieb, M.D. "Our actions underscore our focus on protecting patients while making sure we have an enduring framework for better compounding that is well informed by input from the clinical community. (fda.gov)
The FDA seeks to implement the statutory requirements for bulk drug substances that can be used in compounding in a way that strikes a balance between preserving access to compounded drugs for patients who have a medical need for them while reducing the safety risks and protecting the FDA drug approval process. (fda.gov)
But the FDA said it has received reports that some patients have had some problems after taking the compounded drugs. (upi.com)
The agency warned that patients should not use a compounded drug if an approved drug is available. (upi.com)
Such foot-dragging poses unacceptable and avoidable risks to patients and public health. (aboutlawsuits.com)
An approved New Animal Drug Application ensures the veterinarian is providing quality medicine to patients. (avma.org)
Early results show significant mental health improvements in some patients, while others have not seen success with the drug. (forbes.com)
Salix says the drug will help AIDS patients stick to therapy since they now have a treatment for diarrhea. (wraltechwire.com)
These drugs had already undergone many clinical trials, had been vetted by the approval authorities of various other countries, and had been used by patients for years without safety issues. (mercatus.org)
Compounded products do not have the same safety, quality and effectiveness assurances as our FDA-approved drugs and may expose patients to health risks. (novonordisk-us.com)
Patients should not use a compounded drug if an approved drug is available to treat a patient. (novonordisk-us.com)
Compound versions of drugs are made for individual patients using raw ingredients. (abc7chicago.com)
Because the off-label use of drugs and devices will remain a major part of the practice of medicine in the future, there needs to be a balance between the regulatory authority of the FDA, the circulation of information coming from the pharmaceutical companies, and the ability of physicians to provide the best possible care for their patients. (medscape.com)
On Monday, we stated that the CDC believed that approximately 13,000 patients may have been exposed to the three indicated lots of preservative-free methylprednisolone acetate produced by the compounding center which is frequently referred to by the acronym NECC, continuing investigations by state and local health departments have demonstrated that this number is now closer to 14,000 patients. (cdc.gov)

The FDA is collaborating with the University of Maryland and Johns Hopkins University, two of the agency's Center of Excellence in Regulatory Science and Innovation (CERSI) partners, to gather and analyze information important for developing the list of bulk drug substances that may be used in compounding. (fda.gov)
The studies are intended "to help inform the public and the agency's policies regarding compounded drugs," the agency said in a news release. (medscape.com)
Approved For Release 200WU_- 640261 8000300050005-3 DESCRIPTION OF NEWLY DISCOVERED PROJECT ARTICHOKE/BLUEBIRD MATERIALS INTRODUCTION In conducting an overall review of the Agency's records control schedules, inventories of documents i storage at the Agency's Archives were provided to the various Agency o .f_ces for review. (cia.gov)
The eighteen cartons were immediately brought to Head- quarters for review and a determination as to what, if any, records existed pertaining to Project ARTICHOKE/BLUEBIRD which had not previously been furnished to either the Rock- efeller Commission or Congressional Committees during their inquiries into the Agency's research and experimentation with drugs. (cia.gov)
INFORMATION RELATED TO THE AGENCY'S DRUG TESTING/ INTERROGATION ACTIVITIES INVOLVING HUMAN SUBJECTS A comparison of this material to that which was previously provided again shows that in general the newly discovered documents merely contain additional details concerning such activity rather than significant changes to our previous understanding of the Agency's use of drugs on humans. (cia.gov)

The University of Maryland will be working closely with medical specialty groups and researching information about the use of drug products including certain bulk drug substances historically and in current clinical practice. (fda.gov)
Compound drugs are specialty drugs that combine two or more drugs and are made specifically for an individual. (ctnewsjunkie.com)

Shortages of the drug, commonly sold as Wegovy and Ozempic, has led to the making of compounded versions of the drugs, which is combining or mixing ingredients to meet patient needs. (upi.com)
The salt forms are different active ingredients than those used in the approved drugs. (upi.com)
For example, topical compound drugs are not approved by the FDA and "utilize ingredients that have not been tested for safety and efficacy in a topical form," he said. (ctnewsjunkie.com)
It is the responsibility of companies that obtain drugs, including finished drug products, active pharmaceutical ingredients, and excipients from the Tianjin City region, to take appropriate precautions to ensure the quality of these products before they are distributed and/or used to further manufacture or compound drugs or drug products," the FDA stated in a press release. (pharmacytimes.com)
In compounded products, bioavailability data are available on the active ingredients, but compounded products are not tested in humans. (medscape.com)
Generic drug names-the often tongue-twisting terms in parentheses after brand names-might look like mashups of made-up morphemes, but they are created deliberately to explain chemical structures, actions or indications of active ingredients, and distinguish drugs within classes. (ama-assn.org)

The FDA stated that its goal was to prevent drugs contaminated with toxic chemicals associated with explosions from entering the country. (pharmacytimes.com)
Pursuant to section 68 or 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health conducted a screening assessment of four of five substances referred to collectively under the Chemicals Management Plan as the Furan Compounds Group. (canada.ca)
Tin is a metal that can combine with other chemicals to form various compounds. (cdc.gov)
Sulfur compounds, long used on plants, have been supplemented for some time by other chemicals, especially by compounds of copper, such as Bordeaux mixture . (infoplease.com)
The compound management team acquires chemicals for small molecule screening and registers chemical structures into a hybrid commercial/in-house database. (nih.gov)

The international and national regulations and guidelines regarding barium and barium compounds in air, water, and other media are summarized in Table 8-1. (cdc.gov)
Typically, a Warning Letter notifies a responsible individual or firm that the Agency considers one or more products, practices, processes, or other activities to be in violation of the Federal Food, Drug, and Cosmetic Act (the Act), its implementing regulations and other federal statutes. (wikipedia.org)
When contacted for a response, CAPS declined to comment on the regulations over its compounding facility. (drugtopics.com)
Because of its influence on carbohydrate metabolism and, at the same time, anti-catabolic effects, the misuse of the peptide hormone insulin and its synthetic analogs is prohibited in sports at all times according to the regulations of the World Anti-Doping Agency (WADA). (researchgate.net)
The Canadian Food and Drug Regulations (FDR) state that food (with the exception of fish) which contains chlorinated dibenzo-p-dioxins is adulterated. (canada.ca)
In this paper we discuss a brief history on the drug approval process and the development of FDA regulations over off-label drug promotion, recent legal cases surrounding off-label drug speech, and the risks and benefits of off-label drug promotion in dermatology ( Table 1 ). (medscape.com)

The precipitous increase in compound drug prescriptions, combined with uncertain safety and efficacy, have led large, self-insured groups like large public health plans - including state plans in neighboring Rhode Island, Massachusetts, and New York - to also limit compound drug prescription coverage," Lembo said. (ctnewsjunkie.com)
Several speakers at the meeting emphasized that the FDA has not assessed the quality, safety, efficacy, and bioavailability of compounded BHRT products. (medscape.com)
This is a better way of assessing the efficacy of different drugs in the general, healthy population, and these are the publications that I will mostly use as reference points in this article. (brainblogger.com)

With an average of 10,000 novel molecules that must be screened for each new lead compound developed, and an average of 10 to 15 years of research and development at a cost of up to $1B to manufacture one new drug, pharmaceutical companies must develop new testing regimens that provide more data at a lower cost in order to achieve the economics necessary to remain profitable. (inknowvation.com)
The drug discovery process requires that upwards of 10,000 molecules be screened for each new lead compound developed and relies upon an expensive and time consuming combination of in vitro cell culture-based and in vivo whole animal-based models to identify, validate, and ensure the safety of any resulting potential therapeutic agents. (inknowvation.com)
[ 2 ] This course is so rigorous that for every 5,000 to 10,000 compounds that enter preclinical testing, only one is approved for marketing. (medscape.com)

rather it highlights an old issue that is somewhat inherent to compounding. (drugtopics.com)
This process is frustratingly exacerbated by an unfortunate dichotomy whereby the inexpensive in vitro cell culture systems used for tier 1 screening contribute to failures due to their inabiliy to model the complexity and parallel systems interaction inherent in whole animal models (which are responsible for up to 92% of new compound failures at the clinical level) and because they are not capable of demonstrating species-specific effects. (inknowvation.com)

The ecological risks of the substances in the Furan Compounds Group in this assessment were characterized using the ecological risk classification of organic substances (ERC). (canada.ca)
In general, organic tin compounds are from human-made sources and do not occur naturally in the environment. (cdc.gov)
Organic tin compounds stick to soil, sediment, and particles in water. (cdc.gov)
In water, organic tin compounds are mostly attached to particles in water. (cdc.gov)
Organic tin compounds may also settle out of the water into sediments and may remain unchanged for years. (cdc.gov)
Organic tin compounds may be taken up into the tissues of animals that live in water containing these compounds. (cdc.gov)

State Comptroller Kevin Lembo said Monday that the state has been able to cut spending by about $2 million per month by implementing restrictions on the use of questionable compound drugs. (ctnewsjunkie.com)

In the incident involving Mary Washington Hospital, the cardioplegia solutions came from Central Admixture Pharmacy Services (CAPS), which is typically hired by hospitals to compound a variety of frequently used hospital-based products such as oxytocin and dialysis solutions. (drugtopics.com)
The need for hospitals to have either in-house or outsourced compounding services is as basic as their need to have chemotherapy, total parenteral nutrition, and other common IV mixtures that don't come premixed. (drugtopics.com)
as Health Cluster lead agency, WHO is coordinating the support provided by partners for medical care in hospitals and ensuring that displaced persons have access to health care. (who.int)

In February, JAVMA News talked with the director of the Food and Drug Administration's Center for Veterinary Medicine, Dr. Bernadette Dunham, about drug issues and the investigation into adverse health effects associated with jerky pet treats. (avma.org)
At the same time, the agency published proposed changes to the rules governing veterinary feed directives. (avma.org)
Ocala, Fla. -- The federal government appealed the September decision of a Florida district court that ruled the U.S. Food and Drug Administration overstepped its authority when it tried to shut down a veterinary compounding pharmacy. (dvm360.com)

Along with this action, the agency responded to a citizen petition filed by Public Citizen, related to this substance, granting the petition in part. (fda.gov)
Please contact the FTC and ask the agency to grant our Citizen Petition! (anh-usa.org)
Public Citizen has filed an FDA petition (PDF) to force action on the issue, calling on the agency to immediately add lorcaserin to the withdrawn drug list, and for the FDA to simultaneously update the list whenever a drug is withdrawn or removed from the market due to safety or effectiveness concerns. (aboutlawsuits.com)
The petition comes as a growing number of Belviq lawsuits continue to be filed against Eisai Inc. And Arena Pharmaceuticals in courts nationwide, each involving allegations that former users of the weight loss medication developed cancer, which could have been avoided if the drug makers had properly researched their weight loss treatment and warned consumers about the risks. (aboutlawsuits.com)

Last December, China granted AstraZeneca (AZ) and FibroGen, two global pharmaceutical companies, approval for the new drug roxadustat before any other country. (mercatus.org)
The FDA receives drug user fees, totaling at least $300,000,000 in 2004, from the pharmaceutical companies for the drugs they sell. (newmediaexplorer.org)

When tin is combined with chlorine, sulfur, or oxygen, it is called an inorganic tin compound. (cdc.gov)

An FDA warning letter is an official message from the United States Food and Drug Administration (FDA) to a manufacturer or other organization that has violated some rule in a federally regulated activity. (wikipedia.org)
Some of the facilities these drugs are made at aren't regulated by the U.S. Food and Drug Administration, he said. (ctnewsjunkie.com)
Tell the FDA: Tell the FDA to Stop Trying to Turn Food into Drugs! (anh-usa.org)
The Pew Charitable Trusts joined with the American Public Health Association, the Biotechnology Innovation Organization, the Generic Pharmaceutical Association, the Pharmaceutical Research and Manufacturers of America, and Trust for America's Health to send a letter to the chair and ranking member of the U.S. House and Senate Appropriations subcommittees on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies. (pewtrusts.org)
FDA believes that the judicious use of medically important antimicrobial drugs in the feed or water of food-producing animals needs the scientific and clinical training of a licensed veterinarian. (avma.org)
It is also important to note that any extralabel use of medicated feed is not permitted by law, and we have very specific sections of our Federal Food, Drug, and Cosmetic Act that address that. (avma.org)
A new chemical entity is a drug that contains no active moiety that has been approved by the FDA in any other application submitted under the Federal Food, Drug, and Cosmetic Act. (avma.org)
Due to recent food contamination events outside Canada, dioxins and dioxin-like compounds have gained attention in the media. (canada.ca)
While Vitamin E acetate is often applied to skin or used as a dietary supplement, the U.S. Food and Drug Administration has warned against inhalation because "data is limited about its effects" on the lungs. (rtmagazine.com)
However, since 2000, two new drug classes have been ple committees and professional organi- approved by the U.S. Food and Drug Administration (5,6). (cdc.gov)
Antifungal drugs are approved by the Food and Drug Administration. (infoplease.com)
But we needed to send a message to the Food and Drug Administration from the one place the FDA has to listen to-Congress-and fortunately we and our allies succeeded in doing so. (anh-usa.org)
The NCATS Pharmaceutical Collection (NPC) is a library of all compounds that have been approved for use by the Food and Drug Administration, along with a number of approved molecules from related agencies in foreign countries. (nih.gov)
The U.S. Food and Drug Administration is warning consumers that off-brand forms of drugs like Ozempic and Wegovy could be unsafe. (abc7chicago.com)
Pharmaceuticals are often prescribed for uses beyond those listed on the drug's US Food and Drug Administration (FDA) approved label. (medscape.com)
The same concept has been used by the US Food and Drug Administration (FDA) to establish ``thresholds of regulation'' for indi- rect food additives and adopted by the Joint FAO/WHO Expert Committee on Food Additives for flavoring substances. (cdc.gov)

If current good manufacturing practice (cGMP) violations are cited, it adds a statement regarding the potential impact on requests for approval of export certificates and drug applications. (wikipedia.org)

For their report, they will evaluate the scientific evidence related to these issues and make recommendations on the clinical utility of compounded BHRT products in comparison to that of FDA-approved drug products. (medscape.com)
Compounded BHRT products, including progesterone and testosterone, are sometimes used instead of products approved by the FDA. (medscape.com)
The Endocrine Society writes in a position statement that although compounded BHRT products such as estrogen and progesterone have been marketed as being safer and more effective than FDA-approved products, there is little scientific evidence to support these claims. (medscape.com)
To overcome these detractions and develop an improved tier 1 screening system that reduces the cost and time required for new compound evaluation, 490 BioTech proposes to develop a panel of multiple continuously bioluminescent human cell lines that will permit the simultaneous monitoring of each line to ascertain both the individual effects of compound treatment as well as the downstream effects of a compound's biotransformed metabolic breakdown products in real-time. (inknowvation.com)
Since the use of CBD products could lead to a positive drug test result, Department of Transportation-regulated safety-sensitive employees should exercise caution when considering whether to use CBD products," the agency said in the "clearinghouse update" it issued. (overdriveonline.com)
No samples in this survey had concentrations of dioxins or dioxin-like compounds in excess of European Union limits for either vegetable oils or dairy products. (canada.ca)
The compounds had diverse elemental compositions, and many had molecular structures that are unknown, which the team says makes it promising for the discovery of new natural products. (eurekalert.org)
Since the decision, the FDA has generally only gotten involved in compounding drug cases that involved large numbers of products distributed across state lines. (wbur.org)

Recent policy changes on the regulatory abilities of the US FDA and legal precedents regarding this topic have led to intense debate on free speech about off-label drug use by physicians and drug manufacturers. (medscape.com)

Fifteen synthetic cannabinoids are Schedule I controlled substances ( 3 ), but enforcement is hampered by the continual introduction of new chemical compounds ( 1 , 3 ). (cdc.gov)

With current in vitro screening assays now representing a $1.4B market with a predicted 12% annual growth rate, we believe we possess a product capable of significantly impacting the chemical/drug screening market and, here in particular, advancing our understanding of cytotoxic chemical biotransformations as they pertain to public health and consumer safety. (inknowvation.com)
A scientist from the agency responsible for developing these names offers insight into the process and how it affects patient safety and drug availability. (ama-assn.org)
Under the new standards, the drugs may only be administered in a hospital or clinic, where two psychotherapists must attend to the patient for six to eight hours to ensure safety. (forbes.com)
Rep. DeLauro of Connecticut sent a letter Tuesday to Department of Health and Human Services Secretary Kathleen Sebelius, asking what additional powers would help the department improve the safety of compounded drugs. (wbur.org)
Compounded drugs are not FDA-approved, and the agency does not verify the safety or effectiveness of compounded drugs. (novonordisk-us.com)
Federal regulators are warning about safety concerns amid the rising popularity of drugs like Ozempic and Wegovy for weight loss. (abc7chicago.com)
They are not the same as generic drugs, which are FDA-approved and monitored for safety and effectiveness. (abc7chicago.com)

Wyeth Pharmaceuticals, the maker of Premarin and Prempro , both drugs extracted from the urine of pregnant mares and used in hormone replacement therapy, has asked the FDA to eliminate competition from bio-identical - plant based - hormones, which are a more natural alternative to these drugs. (newmediaexplorer.org)
Tens of thousands of women have forsaken Premarin family drugs for bio-identical hormones. (newmediaexplorer.org)

This is because judicious use involves accurately identifying bacterial disease that is present or likely to be present and selecting the suitable antimicrobial drug. (avma.org)
Since the dawn of the antimicrobial drug era, resistance Barring the arrival in the near future of new antimicro- has shadowed the success of infectious disease therapy. (cdc.gov)
At the same time, what once crobial resistance activities at CDC and was an apparent deluge of antimicrobial drug development co-chairs the federal Interagency Task is now barely a trickle. (cdc.gov)

CVM's Office of New Animal Drug Evaluation has been proactive in helping pharmaceutical sponsors meet the statutory and regulatory standards that provide safe, effective, quality-manufactured, and properly labeled animal drugs. (avma.org)

The agency alleges the compounding pharmacy manufactured and distributed drugs that were tainted because the drugs were made in unsanitary conditions. (beckershospitalreview.com)
Meanwhile, the Tianjin pharmaceutical company had sent 2 other shipments "intended for use in pharmacy compounding" to the United States since the explosion, but the shipments were not found to contain hydrogen cyanide. (pharmacytimes.com)
The agency sent a warning letter expressing concern that the pharmacy was manufacturing drugs and that compounding was being performed outside the context of a valid veterinarian-client-patient relationship. (dvm360.com)
Franck's worked with the FDA to address its concerns and continued its operations until the agency filed suit against the compounding pharmacy in April 2010. (dvm360.com)

And, quite legitimately, R.Ph.s have been compounding these much-needed IV solutions for some time. (drugtopics.com)
Up to 92% of failures for these new compounds at the clinical level are related to cytotoxicity, which often onl manifests during the costly and time consuming process of whole animal testing. (inknowvation.com)
The time each tin compound stays in air, water, or soil differs from compound to compound. (cdc.gov)
But in May, the agency notified Salix that regulators needed more time to review the drug application. (wraltechwire.com)
It was the first time that China approved a drug before a Western nation. (mercatus.org)
While it is tempting to credit China's improvements in drug approval time to procedural reforms, it would be a mistake to consider these reforms in an international vacuum. (mercatus.org)

The FDA is also taking steps regarding its approach to bulk drug substances that are used to make compounded drugs. (fda.gov)
Addressing bulk drug substances used in compounding is an important priority for the agency," said Anna Abram, Deputy Commissioner for Policy, Planning, Legislation and Analysis. (fda.gov)
IV glutathione, one of the bodies most important defenses against disease, could be rejected for various technical reasons-it is not a component of an FDA-approved drug and has no USP monograph, so it's very uncertain whether FDA will add it to the bulk drug list. (anh-usa.org)
The bulk of this material consists of periodical articles and reprints of scientific monographs pertaining to behavior control and the effects and characteristics of drugs. (cia.gov)

The designation is reserved for drugs the DEA says have no proven medical use and are highly addictive. (mapinc.org)

Device Warning Letters (except those issued to IRBs, clinical investigators, sponsors, and monitors involved in clinical trials) include the notice, "Federal agencies are advised of all Warning Letters about devices so that they may take this information into account when considering the award of contracts. (wikipedia.org)
Salix licensed crofelemer from Napo in 2008 and took the compound through phase 3 clinical trials. (wraltechwire.com)
It also rolled out a silent approval process that allows clinical trials to begin 60 days after placing a new drug application if no objection is raised on the CFDA's end. (mercatus.org)
This off-label use includes treatments for disorders not formally reviewed by the FDA, dosages or delivery mechanisms not approved by the agency, or use of the agents in patient populations not tested in FDA approved clinical trials. (medscape.com)

A new policy enacted May 15 requires state employees, retirees, and their family members on the state health plan to get prior approval to get access to these compound drugs. (ctnewsjunkie.com)
The FDA in most cases over the past two decades, has taken at least several years to update the list of withdrawn drugs after the agency determined that a drug was removed from the market because it was unsafe or effective," Dr. Michael Carome, director of Public Citizen's Health Research Group, said in the press release. (aboutlawsuits.com)
Dioxins and dioxin-like compounds are chemical contaminants that have been associated with a wide range of adverse health effects in laboratory animals and humans. (canada.ca)
After decades of prohibition, psychedelic drugs are receiving renewed interest for their potential to treat a host of serious mental health conditions. (forbes.com)
Clinical research and other studies into psychedelics such as psilocybin and MDMA have shown that the drugs have potential therapeutic benefits , particularly for serious mental health conditions such as depression , PTSD, substance misuse disorders and anxiety . (forbes.com)
The researchers say that "I-SMEL" represents a non-invasive way to capture molecules of interest to provide insights into an ecosystem's health or detect novel molecules for future drug discovery efforts. (eurekalert.org)
In 1964, Mr. Justice Emmett Hall - Chair of the Royal Commission on Health Services, which recommended universal insurance for physician services - argued for prescription drug insurance to be the next frontier for Canadian medicare (Canada 1964). (irpp.org)
TMI receives coordinated federal funding and technical assistance from the Centers for Disease Control and Prevention, Washington-Baltimore High Intensity Drug Trafficking Agency, and the National Association of County and City Health Officials to integrate evidence-based and promising strategies. (cdc.gov)
The Yaoundé conference, co-hosted by the World Health Organization (WHO) and the Government of Cameroon, gathered Ministers of Health, global malaria partners, funding agencies, scientists, civil society organizations and other principal malaria stakeholders. (who.int)
These health-based limits are used to sup- impurity and degradant levels in drugs ( ICH, 1997a, port both occupational health and quality programs in 2002a,b,c, 2003 ), with acceptable amounts for residual pharmaceutical research, development and manufactur- solvents in pharmaceuticals, so-called ``permitted daily ing operations. (cdc.gov)

The NCATS Pharmacologically Active Chemical Toolbox (NPACT) is a library of annotated compounds that inform on novel phenotypes, biological pathways and cellular processes. (nih.gov)

All compounded dietary supplements must be pre-approved, with one potential exception-unless it is a component of an approved drug. (anh-usa.org)
Since CBD is an approved prescription drug, it can't be legally included in foods or dietary supplements. (medlineplus.gov)

Furthermore, the use of any drug is associated with potential side effects (e.g., headaches) that might eliminate any potential gains in productivity and creativity . (brainblogger.com)
We can't say for sure, but we believe it is one more agency attempt to eliminate compounding because it represents competition for the big drug companies. (anh-usa.org)

Now, researchers in ACS Central Science report a proof-of-concept device that "sniffs" seawater, trapping dissolved compounds for analyses. (eurekalert.org)
The classified memoranda were largely produced by the Agency and concern the chemical analyses of various drugs, attempts to collect specimens of various drugs, and discussions with non-CIA experts. (cia.gov)

The danger is that the FDA will arbitrarily and nonsensically find them "too difficult to compound," despite their having been compounded for decades. (anh-usa.org)
Before these reforms, the CFDA's drug approval process was marked by decades of lags and slow processes. (mercatus.org)
In preceding decades, the CFDA had been notoriously slow to allow the domestic marketing of drugs approved abroad, lagging behind the US by an average of seven years . (mercatus.org)

If this proves to be true, there may be a role for intravenous vitamin C to help make treatments more effective against antibiotic-resistant drugs. (anh-usa.org)
Belviq (lorcaserin) was introduced in 2012, as the first new diet drug approved in years, after a steady stream of recalls and problems associated with other weight loss treatments. (aboutlawsuits.com)
Compounded IV treatments are also at risk. (anh-usa.org)

Although the total number of NPL sites evaluated for these substances is not known, the possibility exists that the number of sites at which tin and organotin compounds are found may increase in the future as more sites are evaluated. (cdc.gov)
Legal substances can create the same colors as illegal drugs. (propublica.org)
Smart drugs (e.g., nootropics and cognitive enhancers) are defined as substances that improve cognitive function, particularly executive functions, memory, creativity, or motivation-in healthy individuals . (brainblogger.com)

A drug warning letter (except those issued to institutional review boards (IRBs), clinical investigators, sponsors, and clinical trial monitors) includes a statement of implications for the award of federal contracts. (wikipedia.org)

After 2 explosions at a chemical warehouse this summer in Tianjin, China, the FDA increased surveillance of drug shipments. (pharmacytimes.com)
Police officers use the inexpensive chemical kits to make drug arrests by the thousands every year. (propublica.org)
1968 have been chemical modifications of existing drugs. (cdc.gov)
A rather heterogeneous group, these compounds have different chemical structures, different mechanisms of action, and different adverse effects. (medscape.com)
The NExT Diversity Libraries contain chemical scaffolds across 10 commercial suppliers and compounds that were selected to fall within the boundaries of drug-like chemical space (e.g. (nih.gov)
Our analytical chemistry experts and state-of-the-art lab support early-stage chemical development byanalyzing and purifying small molecules and other compounds. (nih.gov)

But many experts and advocates say the current classification is increasingly at odds with scientific studies on marijuana, which suggest the drug has medical value in treating chronic pain, seizures and a number of other conditions, with a lower addiction rate than alcohol. (mapinc.org)

After sampling the water, the researchers assessed the captured compounds with mass spectrometry. (eurekalert.org)
As many as 13,000 people received steroid shots from the New England Compounding Center of Framingham, Mass, according to The Centers for Disease Control and Prevention. (wbur.org)

However, not all compound drugs carry a risk, Lembo said, but many have not been tested to find out if they are medically necessary. (ctnewsjunkie.com)
Therefore, when production claims for medically important antimicrobials are voluntarily removed from the approved labeling of these drugs, any further use of these drugs in medicated feed for production purposes will be considered an extralabel use and, thus, illegal. (avma.org)

The decision by the veterinarian to use a specific approved drug or combination drug is based on factors such as the mode of antibacterial action, drug distribution in specific tissues, and the duration of effective drug levels at the site of infection. (avma.org)

In effect, the FDA has been on a course to regulate compounded drugs and supplements out of existence. (anh-usa.org)
Big Pharma has, in our view, taken control of the agency that is supposed to regulate it. (anh-usa.org)

The number of prescriptions for these drugs also has dropped from 785 per month to 221 per month. (ctnewsjunkie.com)

If police chose to use field tests to help make arrests, the results "should not be used as sole evidence for the identification of a narcotic or drug of abuse" in the courts, chemists at the U.S. National Bureau of Standards wrote the same year. (propublica.org)
Fungicides used on wood, including creosote, prevent dry rot, and certain compounds are used to make fabrics resistant to mildews. (infoplease.com)

The last bit is important: there are many drugs that were specifically developed to enhance brain functions in people with various cognitive disorders or deficits. (brainblogger.com)

Diseases3

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Psychiatry and Psychology6

Phenomena and Processes1

Disciplines and Occupations17

Anthropology, Education, Sociology and Social Phenomena54

Technology, Industry, Agriculture12

Humanities5

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FDA's6

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20172

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