• puberty
  • LOS ANGELES - A team of researchers led by Vicente Gilsanz, MD, PhD, director of Clinical Imaging at The Saban Research Institute of Children's Hospital Los Angeles, determined that the onset of puberty was the primary influence on adult bone mineral density, or bone strength. (healthcanal.com)
  • Given that the rate of decline of bone mass in adulthood is approximately 1% to 2% each year, a 10% to 20% increase in bone density resulting from a natural early puberty corresponds to an additional 10 to 20 years of protection against the normal age-related decline in bone strength. (healthcanal.com)
  • In many countries throughout the world, the age at which puberty occurs among girls-manifested as breast development, appearance of pubic hair, and onset of menarche-has been commencing earlier. (thesoyfoodscouncil.com)
  • These trends in pubertal development raise concerns because early onset of puberty may negatively influence the future health of adolescent girls. (thesoyfoodscouncil.com)
  • genotypes
  • We tested the association between the ATM genotypes and HNPCC age of onset by survival analysis. (aacrjournals.org)
  • We tested the association between age of onset and the DNMT3b genotypes by comparing Kaplan-Meier survival curves, evaluating the homogeneity of the curves using the log-rank test and Wilcoxon's test, and estimating the association using the Cox proportional hazards regression model to adjust for potential demographic confounding factors. (aacrjournals.org)
  • HNPCC
  • Revealing such associations in MMR mutation carriers may improve risk estimates and help to identify individuals who are genetically susceptible to developing HNPCC at an earlier age. (aacrjournals.org)
  • Combining knowledge of an individual's DNMT3b genotype with information on other genetic and environmental risk factors may improve risk estimates and help to identify individuals who are genetically susceptible to developing HNPCC at an earlier age. (aacrjournals.org)
  • researchers
  • By applying a new technique that combines independent lines of genomic evidence, Duke University Medical Center researchers and colleagues have identified a single gene that influences the age at which individuals first show symptoms of Alzheimer s and Parkinson s diseases. (innovations-report.com)
  • The researchers overlaid three independent lines of genetic evidence to reveal those genes more likely to play a role in the disorders age at onset -- a method, called genomic convergence, which the Duke team developed. (innovations-report.com)
  • The experiment uncovered four genes, including GSTO1, located in the region of the genome earlier linked to age at onset, the researchers report. (innovations-report.com)
  • Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. (eurekalert.org)
  • In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice. (eurekalert.org)
  • Researchers from the Mayo Clinic Robert and Arlene Kogod Center on Aging found that exercise prevents premature senescent cell accumulation and protects against the damaging effects of an unhealthy diet, including deficiencies in physical, heart, and metabolic function, equivalent to diabetes. (eurekalert.org)
  • In a study published in May 2014 in the journal Addiction , a team of Spanish and American researchers attempted to determine if the effects of diagnosable gambling problems that arise before the age of 26 differ in any important way from the effects of such problems that arise after affected individuals turn 26. (elementsbehavioralhealth.com)
  • These researchers also wanted to know if the groups of people who develop "early-onset" gambling disorder have different underlying characteristics than the groups of people who develop "late-onset" gambling disorder. (elementsbehavioralhealth.com)
  • In the study published in Addiction , researchers from five Spanish institutions and two U.S. institutions used data from a U.S.-based project called the National Epidemiologic Survey on Alcohol and Related Conditions to determine if people with diagnosable, early-onset gambling problems differ significantly from people with diagnosable, late-onset gambling problems. (elementsbehavioralhealth.com)
  • In line with the practices of previous research teams, the researchers involved in the current project used the study participants' 26th birthdays as the cutoff point between early-onset gambling problems and late-onset gambling problems. (elementsbehavioralhealth.com)
  • The researchers concluded that, in these two important respects, people with early-onset gambling problems don't differ substantially from people with late-onset problems. (elementsbehavioralhealth.com)
  • Intron
  • We examined association between three PPARα gene polymorphisms (an A→C variant in intron 1, the L162V variant, and the intron 7 G→C variant) and age at diagnosis of type 2 diabetes in 912 Caucasian type 2 diabetic subjects. (diabetesjournals.org)
  • variation
  • However, among mutation carriers, significant inter-individual variation in cancer age of onset has been observed. (aacrjournals.org)
  • These data indicate that PPARα gene variation influences the onset and progression of type 2 diabetes. (diabetesjournals.org)
  • We therefore examined association between variation in the PPARα gene and age at diagnosis (as a surrogate for age of onset) and progression to type 2 diabetes in Caucasian type 2 diabetic participants in the University College Diabetes and Cardiovascular Study (UDACS) ( 16 ) and Ealing Diabetic Study of Coagulation (EDSC). (diabetesjournals.org)
  • diagnosis
  • Atopic dermatitis was defined by a doctor's diagnosis reported by the parents of children up to 4 years of age, by questionnaires, and/or by positive SCORAD scores from 1 year of age and according to the age of onset within or after the first year of life. (biomedsearch.com)
  • For those with biologic use, average age at time of diagnosis of psoriasis was 28.2 ± 14.7 years, compared with 40.4 ± 18.1 years for those who had not received biologics. (biomedsearch.com)
  • The following is a list of conditions and complications associated with NF-1, and, where available, age range of onset and progressive development, occurrence percentage of NF-1 population, method of earliest diagnosis, and treatments and related medical specialties. (wikipedia.org)
  • adolescents
  • We have used data from adolescents (n=5,392) ages 10-18 who participated in the 2003 Tobacco Survey, a representative sample of adolescents in Northwest Ohio. (mdpi.com)
  • Khuder SA, Price JH, Jordan T, Khuder SS, Silvestri K. Cigarette Smoking among Adolescents in Northwest Ohio: Correlates of Prevalence and Age at Onset. (mdpi.com)
  • gene
  • The families also met one of two other criteria: either one individual in the family developed Parkinson's disease before age 54 years, or two affected siblings had identical versions of the parkin gene. (bio-medicine.org)
  • The fact that even heterozygotes developed Parkinson's disease at an earlier age than those with two normal copies indicates that the gene's effect may be stronger than previously recognized, and that screening for mutations in the gene may help identify those at risk of developing the condition. (bio-medicine.org)
  • diabetes
  • Diabetes Measure Kit Ii Age Onset Type research has shown that controlling ACE Inhibitor Treatment in Jasper's Page has more information on this treatment. (bestcities.eu)
  • Low magnesium levels not only make controlling blood sugar more difficult but also increase risk Always record your test Diabetes Measure Kit Ii Age Onset Type results in your logbook. (bestcities.eu)
  • METHODS
  • Current research is being performed to develop treatment methods for the aforementioned laminopathies and to investigate the role lamins play in the aging process. (wikipedia.org)
  • participants
  • Studies looking at psychosocial factors influencing disease onset found that cohorts of participants with MS had a higher prevalence of negative life events, self-defined family problems, and poorer utilization of social support resources compared to healthy controls ( 15 ). (frontiersin.org)
  • Participants from this project submitted detailed information on their demographic backgrounds (age, racial/ethnic background, income level, gender, etc.), as well as information on their age when they first experienced gambling problems, their mental health histories and their involvement in problematic substance use. (elementsbehavioralhealth.com)
  • people
  • For instance, the general age of onset for the spinal disease scoliosis is "10-15 years old," meaning that most people develop scoliosis when they are of an age between ten and fifteen years. (wikipedia.org)
  • He is the co-author of a manual, Guidelines for social and economic rehabilitation of the rural blind, which prescribes guidelines for the rehabilitiaon of visually impaired people and a recipient of the All India Confederation of the Blind Award in 1987 and the International Award for Community Services Overseas of the Help the Aged, UK in 1991. (wikipedia.org)
  • PVD is rare in emmetropic people under the age of 40 years, and increases with age to 86% in the 90s. (wikipedia.org)
  • citation needed] People with myopia (nearsightedness) greater than 6 diopters are at higher risk of PVD at all ages. (wikipedia.org)
  • develop
  • A British physician, Muir noted a patient with many keratoacanthomas who went on to develop several internal malignancies at a young age. (wikipedia.org)
  • over 75% of those over the age of 65 develop it. (wikipedia.org)
  • individuals
  • However, they did conclude that individuals with early-onset gambling problems tend to share certain underlying characteristics, including such things as being male and relatively young, making less than $70,000 a year, remaining unmarried and having certain types of diagnosable personality disorders. (elementsbehavioralhealth.com)
  • American Federati
  • The major funding for the study was provided by the National Institute on Aging, the National Institute of Neurological Disorders and Stroke, the Alzheimer s Association, the Institute de France, and the American Federation for Aging Research. (innovations-report.com)
  • impact
  • There were substantial age-PR interactions for FSIQ (p = 0.003) and 3 domain scores, indicating a lessening impact of PR with increasing age. (luriechildrens.org)
  • study
  • In conclusion, the results of this first of its kind study show that soy intake does not affect the age at which girls begin menstruation. (thesoyfoodscouncil.com)
  • We think at both a biological level and a clinical level, poor nutrition choices and inactive lifestyles do accelerate aging," says Nathan LeBrasseur, Ph.D., director of the Center on Aging's Healthy and Independent Living Program and senior author of the study. (eurekalert.org)
  • cases
  • JXG usually manifests with multiple lesions on the head and neck in cases with children under six months of age. (wikipedia.org)
  • The most common symptom, in over 95% of cases, is a sudden-onset headache located behind the eyes or around the temples. (wikipedia.org)