• cell
  • TWEAK increased HMGB1 mRNA expression and protein secretion in human acute monocytic leukemia cell line cultured monocytes. (ahajournals.org)
  • TWEAK also increased monocyte chemoattractant protein-1 secretion in human acute monocytic leukemia cell line cells, an effect blocked with an HMGB1 small interfering RNA. (ahajournals.org)
  • The symptom information on this page attempts to provide a list of some possible signs and symptoms of Hairy cell leukemia . (rightdiagnosis.com)
  • This signs and symptoms information for Hairy cell leukemia has been gathered from various sources, may not be fully accurate, and may not be the full list of Hairy cell leukemia signs or Hairy cell leukemia symptoms. (rightdiagnosis.com)
  • Furthermore, signs and symptoms of Hairy cell leukemia may vary on an individual basis for each patient. (rightdiagnosis.com)
  • Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. (wikipedia.org)
  • Hairy cell leukemia makes up approximately 2% of all leukemias, with fewer than 2,000 new cases diagnosed annually in North America and Western Europe combined. (wikipedia.org)
  • Hairy cell leukemia was originally described as histiocytic leukemia, malignant reticulosis, or lymphoid myelofibrosis in publications dating back to the 1920s. (wikipedia.org)
  • In hairy cell leukemia, the "hairy cells" (malignant B lymphocytes) accumulate in the bone marrow, interfering with the production of normal white blood cells, red blood cells, and platelets. (wikipedia.org)
  • Hairy cell leukemia is commonly diagnosed after a routine blood count shows unexpectedly low numbers of one or more kinds of normal blood cells, or after unexplained bruises or recurrent infections in an otherwise apparently healthy patient. (wikipedia.org)
  • As with many cancers, the cause of hairy cell leukemia is unknown. (wikipedia.org)
  • Recent studies have identified somatic BRAF V600E mutations in all patients with the classic form of hairy cell leukemia thus sequenced, but in no patients with the variant form. (wikipedia.org)
  • The U.S. Institute of Medicine (IOM) announced "sufficient evidence" of an association between exposure to herbicides and later development of chronic B-cell leukemias and lymphomas in general. (wikipedia.org)
  • However, the IOM extrapolated data from chronic lymphocytic leukemia and non-Hodgkin lymphoma to conclude that HCL and other rare B-cell neoplasms may share this risk factor. (wikipedia.org)
  • this patient later developed hairy cell leukemia (a B cell disease), but HTLV-2 was not found in the hairy cell clones. (wikipedia.org)
  • side effect
  • Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom. (rightdiagnosis.com)
  • this can have the side effect of making the person feel full even when he or she has not eaten much. (wikipedia.org)