• hepatitis
  • Despite the fact that this killed whole virus strategy is widely exercised to prevent diseases like polio, influenza, cholera, mumps, rabies, typhoid fever and hepatitis A in the past, it failed to receive any serious attention in the effort to develop vaccines against HIV for various scientific, economical and technical reasons. (wikipedia.org)
  • A number of specific immunoglobulin formulations are also available including for hepatitis B, rabies, tetanus, varicella infection, and Rh positive blood exposure. (wikipedia.org)
  • titer standard
  • Note: RFFIT is the rabies titer standard established by the Centers for Disease Control within the USA [0.1 IU/mL] and the World Health Organization [0.5 IU/mL] for export to other rabies-free locations to be adequate to protect humans, not dogs, against rabies. (dogs4dogs.com)
  • After completion of the peer-review process, it is our hope that this data will establish the world's first canine rabies titer standard. (dogs4dogs.com)
  • Centers for Dis
  • While the Centers for Disease Control released information in 2007 indicating that canine rabies was all but wiped out in the United States, it is still necessary to immunize dogs against the disease. (vetinfo.com)
  • antigen
  • An immunologic adjuvant is defined as any substance that acts to accelerate, prolong, or enhance antigen-specific immune responses when used in combination with specific vaccine antigens. (wikipedia.org)
  • Because immune systems have evolved to recognize these specific antigenic moieties, the presence of an adjuvant in conjunction with the vaccine can greatly increase the innate immune response to the antigen by augmenting the activities of dendritic cells (DCs), lymphocytes, and macrophages by mimicking a natural infection. (wikipedia.org)
  • In order to understand the links between the innate immune response and the adaptive immune response to help substantiate an adjuvant function in enhancing adaptive immune responses to the specific antigen of a vaccine, the following points should be considered: Innate immune response cells such as Dendritic Cells (DCs) engulf pathogens through a process called phagocytosis. (wikipedia.org)
  • Lyme
  • The company is conducting research in the field of zoonotic disease, specifically in lyme disease and rabies, with a goal of developing vaccines and offers some its recombinant proteins to life sciences researchers under a program called BioShare. (wikipedia.org)
  • booster
  • These results, which will have been obtained using the same federal standard upon which all currently licensed rabies vaccines and rabies laws and regulations are based, should establish the scientific foundation upon which the legally required rabies booster intervals for dogs can be extended to 5 or 7 years. (dogs4dogs.com)
  • While Dr. Schultz supports the use of titer tests to see if booster vaccines are necessary (or not), he isn't a proponent of smaller doses. (embracepetinsurance.com)
  • The first rabies injection should be given between the ages of 3 to 6 months with a booster injection given at 1 year. (vetinfo.com)
  • CHALLENGE FUND
  • The Rabies Challenge Fund has just received the commitment from a USDA-approved facility to perform the first of the challenge phases of our 5 and 7-year studies. (dogs4dogs.com)
  • Currently, The Rabies Challenge Fund will need to raise an additional $24,847 to cover the challenge facility fees. (dogs4dogs.com)
  • I'm a great supporter of, and volunteer fundraiser for, the Rabies Challenge Fund . (dogs4dogs.com)
  • strain
  • CDC and the Food and Drug Administration (FDA) have been notified that a recent quality-assurance test of IMOVAX ® Rabies Vaccine (Aventis Pasteur, Swiftwater, Pennsylvania) identified the presence of noninactivated Pitman-Moore virus (the attenuated vaccine strain) in a single product lot. (cdc.gov)
  • Although unlikely, a theoretical possibility exists that persons who received vaccine from a recalled lot could have been exposed to the noninactivated Pitman-Moore vaccine strain of rabies virus. (cdc.gov)
  • The Austrian-South African immunologist Max Sterne (1905-1997) developed an attenuated live animal vaccine in 1935 that is still employed and derivatives of his strain account for almost all veterinary anthrax vaccines used in the world today. (wikipedia.org)
  • With little help from colleagues, Sterne performed small-scale experiments which isolated the "Sterne strain" (34F2) of anthrax which became, and remains today, the basis of most of the improved livestock anthrax vaccines throughout the world. (wikipedia.org)
  • virus
  • Killed virus vaccines like those for rabies virus…can trigger immediate and delayed adverse vaccine reactions. (dogs4dogs.com)
  • As soon as a USDA licensed facility can be reserved, we plan to challenge some of those dogs with rabies virus to determine if the memory response demonstrated actually correlates with protection. (dogs4dogs.com)
  • The vaccine lot containing noninactivated virus was not distributed. (cdc.gov)
  • SAV001-H is the first preventive HIV vaccine using a killed or "dead version" of HIV-1 virus. (wikipedia.org)
  • At the moment, there are 16 animal vaccine based on this killed virus method including the feline immunodeficiency virus (which is closely related to HIV) vaccine for cats. (wikipedia.org)
  • Fourth, the early studies with the monkeys using the killed simian immunodeficiency virus (SIV) vaccine showed some optimism but it turned out that the protection was attributable to responses to both the cellular proteins on the SIV vaccine and on the challenge virus grown not in monkey cells but in human cells. (wikipedia.org)
  • Nevertheless, to date many scientists and researchers insist on a belief that the killed whole virus strategy is a feasible option for an HIV vaccine. (wikipedia.org)
  • Indeed, Jonas Salk developed a therapeutic HIV vaccine in 1987, called Remune now being developed by Immune Response BioPharma, Inc., is based on the killed whole virus approach. (wikipedia.org)
  • In 1885, Pasteur produced his celebrated first vaccine for rabies by growing the virus in rabbits and then weakening it by drying the affected nerve tissue. (wikipedia.org)
  • immunization
  • Rabipur is indicated for active immunization against rabies in individuals of all ages. (drugs.com)
  • Information about human rabies prevention based on current recommendations of the Advisory Committee on Immunization Practices (ACIP) is available at http://www.cdc.gov/mmwr/preview/mmwrhtml/00056176.htm . (cdc.gov)
  • immune response
  • However, it was soon found that more scrupulous attention to cleanliness actually seemed to reduce the effectiveness of the vaccines, and that the contaminants - "dirt" - actually enhanced the immune response. (wikipedia.org)
  • sarcoma
  • There have been no specific associations between development of vaccine-associated sarcoma and vaccine brand or manufacturer, concurrent infections, history of trauma, or environment. (wikipedia.org)
  • 1950s
  • Human anthrax vaccines were developed by the Soviet Union in the late 1930s and in the US and UK in the 1950s. (wikipedia.org)
  • There were epidemics of poliomyelitis that were only controlled following the development of a vaccine in the 1950s. (wikipedia.org)
  • Therapeutic
  • Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines against cancer are being investigated). (wikipedia.org)
  • Researchers reported that the therapeutic vaccine induced robust cellular immune responses in animal tests recently conducted. (wikipedia.org)
  • serum
  • Rabies immune globulin or antirabies serum, equine (ARS) is given in conjunction with rabies vaccine to provide immune protection until an antibody response can occur. (drugs.com)
  • This vaccine contains residues of polygeline, chicken proteins (e.g., ovalbumin), human serum albumin, and may contain traces of neomycin, chlortetracycline and amphotericin B. See sections 4.3 and 4.4. (drugs.com)
  • humans
  • Vaccines have contributed to the eradication of smallpox, one of the most contagious and deadly diseases in humans. (wikipedia.org)
  • Anthrax vaccines were developed in the Soviet Union in the 1930s and available for use in humans by 1940. (wikipedia.org)
  • Recommendations
  • Health-care providers should contact persons who received recalled vaccine to implement the recommendations outlined in this notice (see Recommendations for Persons Who Received Recalled Vaccine). (cdc.gov)