• Inbred and outbred mouse and rat strains have very different susceptibility to Sendai virus infection. (wikipedia.org)
  • Treatment of both strains with exogenous IFN before and during viral infection led to an increase in survival time in C57BL/6 mice, but all animals of both strains ultimately succumb to SeV caused disease. (wikipedia.org)
  • While oxidative tension Pyroxamide (NSC 696085) appears to have an effect on cell enlargement enhances following ADSC-mediated angiogenesis enlargement and oxidative stress resistance of ADSCs isolated from three genetically diverse inbred strains of adult female mice: C57BL/6J (B6) BALB/cByJ (BALB) and DBA/2J (D2) mice. (academicediting.org)
  • To this aim, we evaluated whether Chronic Unpredictable Stress (CUS) differently affected coping and mesoaccumbens dopamine (DA) responses to stress challenge by adult mice of the C57BL/6J (B6) and DBA/2J (D2) inbred strains depending on early life experience (Repeated Cross Fostering, RCF). (uniroma1.it)
  • We used the Hamilton Eye Institute (HEI) retinal dataset ( www.genenetwork.org ) to identify genomic loci that modulate expression of genes in the p53 pathway in recombinant inbred BXD mouse strains using a QTL systems biology-based approach. (transhumanist.ru)
  • On documents from the supplier provided with the rodents, the 'JN' after C57B6 and the "JNIA" after BALB/c indicates that the foundation stock for these mouse strains came from The Jackson Laboratory but were bred in the NIA colony. (nih.gov)
  • Our genetically engineered mouse model, or GEMM, team offers state-of-the-art services for the development and maintenance of transgenic mouse strains, including all modern genome editing tools and expertise in mouse transgenesis. (fredhutch.org)
  • Strains on common inbred backgrounds are most successful. (fredhutch.org)
  • Acetate producer probiotics differentially modulated and altered the genus abundance of specific bacteria, such as Akkermansia and Allistipes , in mouse strains. (biomedcentral.com)
  • Experimental studies generally use different probiotic species in different mouse strains and various protocols to induce allergic inflammation, which complicates relevant comparisons and validations. (biomedcentral.com)
  • Researchers intercrossed two inbred mouse strains, C57BL/6N and C3H/HeN, and measured DNA methylation patterns in the livers of parents and offspring using whole-genome bisulfite sequencing. (nih.gov)
  • One place you can go to find datasets (particularly on commonly used inbred strains) is the Mouse Phenome Database (MPD). (jax.org)
  • The repertoires of highly responding antigens in humans and mice overlapped, but were not identical. (ox.ac.uk)
  • In this review, we discuss translational approaches that aim to bridge results from unbiased genome-wide screens using mouse models to anxiety disorders in humans. (biomedcentral.com)
  • These studies have led to the identification of completely novel biological pathways that regulate anxiety in mice and humans, and that can be further investigated as targets for therapy. (biomedcentral.com)
  • Such mice have been extensively used as study models of telomere biology and function in humans. (nature.com)
  • In this study, we examined differences in the stress response between FGF21 knockout (KO) mice and wild-type (WT) mice after social defeat stress (SDS). (tokushima-u.ac.jp)
  • Moreover, Cyp19a1 mRNA levels increased in the hypothalamus of estrogen receptor-alpha knockout female mice (Esr1KO). (nel.edu)
  • It is noted that human telomeres are much shorter than mouse telomeres and that mouse somatic cells continue expressing telomerase in adulthood 28 , such that only late-generation telomerase knockout ( Terc −/− ) mice exhibit short telomere-associated phenotypes, including accelerated aging, reduced injury repair and predisposition to tumorigenesis 29 . (nature.com)
  • Estrogen receptor-alpha immunoreactivity in the arcuate hypothalamus of young and middle-aged female mice. (nel.edu)
  • We counted ER-alpha-immunoreactive (IR) cells in the Arcuate hypothalamus of 6-week-old (young) and 18-month-old (middle-aged) C57BL/6J female mice, sacrificed at vaginal opening and diestrous, respectively. (nel.edu)
  • However, the calculated percentage of ER-alpha IR cells is similar in both young and middle aged mice, 30% and 29%, respectively. (nel.edu)
  • Yaghmaie F, Saeed O, Garan S, Voelker M, Sternberg H, Timiras P. Estrogen receptor-alpha immunoreactivity in the arcuate hypothalamus of young and middle-aged female mice. (nel.edu)
  • However, the adult spinal cord has limited ability to produce new neurons. (nih.gov)
  • The functional significance of adult-born neurons in this region has been characterized using context fear conditioning, a Pavlovian paradigm in which animals learn to associate a location with danger. (nih.gov)
  • Ablation or silencing of adult-born neurons impairs both acquisition and recall of contextual fear conditioning, suggesting that these neurons contribute importantly to hippocampal memory. (nih.gov)
  • Because most studies of adult neurogenesis have relied on methods that permanently ablate neurogenesis throughout the entire hippocampus, little is known about how the function of adult-born neurons varies along the dorsal-ventral axis. (nih.gov)
  • The use of Tac2-Cre mice and Cre-dependent viral vectors for specific manipulations of these neurons allows the experimenter to manipulate a small population of neurons without affecting surrounding populations. (nature.com)
  • Male C57BL/6 J mice were separated into various PCMS groups: a control group with sawdust on the floor of the rearing cage (C), a group with mesh wire on the floor (M), and a group with water just below the mesh wire (W). Activation of lateral hypothalamic orexin neurons was assessed using immunofluorescence. (tokushima-u.ac.jp)
  • Action of prolactin, prolactin-releasing peptide and orexins on hypothalamic neurons of adult, early postnatally overfed rats. (nel.edu)
  • Davidowa H, Plagemann A. Action of prolactin, prolactin-releasing peptide and orexins on hypothalamic neurons of adult, early postnatally overfed rats. (nel.edu)
  • The virus can be detected in mouse colonies worldwide, generally in suckling to young adult mice. (wikipedia.org)
  • We investigate the molecular mechanisms underlying the depletion of ovarian follicular reserve in young adult females following exposure to obesogenic diet in early life. (cam.ac.uk)
  • For the first time, our study focused on old (12-month-old) mdx mice, displaying marked chronic muscle lesions, similar to the lesions observed in human DMD, in comparison to young-adult (3-month-old) mdx mice displaying only mild muscle lesions with no fibrosis. (ox.ac.uk)
  • By using an original approach combining a specific animal model, state-of-the-art histology/morphometry techniques, and functional nuclear magnetic resonance, we demonstrated that the microvascular system is almost normal in young-adult in contrast to old mdx mice, displaying marked microvessel alterations, and the functional repercussions on muscle perfusion and bioenergetics after a hypoxic stress vary depending on stage of pathology. (ox.ac.uk)
  • The virus is responsible for a highly transmissible respiratory tract infection in mice, hamsters, guinea pigs, rats, and occasionally marmosets, with infection passing through both air and direct contact routes. (wikipedia.org)
  • The Translational Research Branch within the NIA Division of Aging Biology maintains colonies of barrier-raised , Specific Pathogen-Free (SPF) male and female mice and rats under a contractual arrangement with Charles River Laboratories. (nih.gov)
  • Single unit activity was extracellularly recorded in brain slices from adult control rats (CL) and from rats previously raised in small litters (SL). (nel.edu)
  • This was determined by testing the efficacy of a TNF alpha synthesis lowering agent 3,6′-dithiothalidomide on neuroinflammation-induced cognitive impairment exhibited in the 3x Tg AD mouse model, mice challenged with Aβ 1-42 peptide, and LPS-challenged rats. (nih.gov)
  • Finally, the comparative analyses of behavioral and neural phenotypes expressed by B6 and D2 mice suggest some translationally relevant hypotheses of genetic risk factors for psychiatric disorders. (uniroma1.it)
  • To complement human genetic studies several groups have used mouse models of anxiety-like behavior for identification of genes and biological pathways that regulate anxiety. (biomedcentral.com)
  • A number of laboratories have used various exogenous and endogenous stimuli (e.g., hyperoxia, metals and endotoxin) to develop genetic models of ALI in mice. (medscape.com)
  • CeA-Tac2 antagonism and its pharmacogenetic temporal inhibition impair fear memory in male mice. (nature.com)
  • A mutant mouse model mimicking this variant produces a truncated LRRC23 at the C-terminus that fails to localize to the sperm tail, causing male infertility due to defective sperm motility. (elifesciences.org)
  • As of July 1, 2023, limited numbers of male BALB/c mice are available for distribution. (nih.gov)
  • Groups of 30 male and 30 female C57BL/6J mice were weighed starting at 10 weeks of age until 78 weeks of age. (jax.org)
  • Sera from adults vaccinated with an OMV vaccine were used to screen 91 outer membrane proteins (OMPs) incorporated in an antigen microarray panel. (ox.ac.uk)
  • Levels of the synaptic proteins, SNAP25 and synaptophysin, were found to be elevated in older symptomatic drug-treated 3xTg-AD mice compared to vehicle-treated ones, indicative of a preservation of synaptic function during drug treatment. (nih.gov)
  • Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. (oregonstate.edu)
  • A study in France reported antibodies to SeV in 17% of mouse colonies examined. (wikipedia.org)
  • DESIG N: BALB/c mice were exposed to saline, HI-6 in a dose 1-100 mg/kg and/or 1 keyhole limpet hemocyanin (KLH) 1 mg/kg. (nel.edu)
  • Three weeks of CUS increased the helplessness expressed in the Forced Swimming Test (FST) and the Tail Suspension Test by RCF-exposed female mice of the D2 strain. (uniroma1.it)
  • Moreover, female D2 mice with both RCF and CUS experiences showed inhibition of the stress-induced extracellular DA outflow in the Nucleus Accumbens, as measured by in vivo microdialysis, during and after FST. (uniroma1.it)
  • The present results support genotype-dependent additive effects of early experiences and adult adversities on behavioral and neural responses to stress by female mice. (uniroma1.it)
  • Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet. (cam.ac.uk)
  • Female mice were exposed to either maternal obesogenic (high fat/high sugar) or maternal control dietin uteroand during lactation, then weaned onto either obesogenic or control diet. (cam.ac.uk)
  • Maternal diet thus plays a central role in determining follicular reserve in adult female offspring. (cam.ac.uk)
  • To understand the relevance of microbial composition colonization in the development of allergic diseases, we implanted female C57BL/6 mice with A/J embryos to naturally modulate the microbial composition of A/J mice, which increased gut microbiota diversity and reduced eosinophilic inflammation in A/J. These data demonstrate the central importance of microbiota to allergic phenotype severity. (biomedcentral.com)
  • Although the team has not determined exactly how these female mice had a loss of DNA methylation, the work bolsters the importance of epigenetics in influencing gene regulation. (nih.gov)
  • METHODS: The study included 85 nonhospitalized, symptomatic adults, who were enrolled from September 2020 to November 2021. (cdc.gov)
  • Using a diet-induced obesity model, we show that TLR3-deficient mice had enhanced glycemic control, facilitated by elevated insulin secretion. (ox.ac.uk)
  • These animals are for research that is explicitly on aging and are not a source of adult animals for other areas of research. (nih.gov)
  • Estrogen receptor alpha (Esr1) regulates aromatase (Cyp19a1) expression in the mouse brain. (nel.edu)
  • In the mouse brain, a 36 kb distal promoter (l.f) regulates the Cyp19a1 gene that encodes aromatase, the key enzyme for estrogen biosynthesis. (nel.edu)
  • Adult hippocampal neurogenesis is involved in many behaviors that are disrupted in ASD, including cognition, anxiety, and social behaviors. (princeton.edu)
  • Here, we examined adult neurogenesis in the hippocampus, as well as astroglia and microglia in the hippocampus, mPFC, and striatum of two models that display autism-like phenotypes, Cntnap2 and Shank3 transgenic mice. (princeton.edu)
  • Future work is needed to explore the functional contribution of adult neurogenesis to autism-related behaviors as well as to temporally characterize glial plasticity as it is associated with ASD. (princeton.edu)
  • 2005. Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets. . (oregonstate.edu)
  • There was also a significant decrease in the expression levels of miR‑135a‑3p, miR‑129b‑5p and miR‑504‑3p, and an increase in miR‑122‑5p expression levels in circulating EVs in mice treated with HFD and patients with NAFLD. (ox.ac.uk)
  • Our real-time (RT) -PCR results revealed that the mRNA expression of the stress- and sleep-related gene gamma-aminobutyric acid A receptor subunit alpha 2 was significantly lower in WT mice than in KO mice. (tokushima-u.ac.jp)
  • In ALD patients, but not in ALD deficient mice, iNKT cell frequency and CD1d expression on the surface of B cells are slightly decreased. (ox.ac.uk)
  • Several methods, such as quantitative trait locus mapping, gene expression profiling, and proteomics, have been used in various mouse models of anxiety to identify genes that regulate anxiety or play a role in maintaining pathological anxiety. (biomedcentral.com)
  • In vitro, promoter l.f interacts with estrogen receptor alpha (Esr1) to mediate Cyp19a1 mRNA expression and enzyme activity in mouse hypothalamic neuronal cell lines. (nel.edu)
  • The in vivo mechanisms that control mammalian brain aromatase expression during fetal and adult development, however, are not thoroughly understood. (nel.edu)
  • Taken together, our findings might indicate that Esr1 has crucial roles in the in vivo regulation of aromatase expression in the brain during fetal and adult life. (nel.edu)
  • We examined the GATA2 expression pattern in the adult kidney by tracing green fluorescent protein (GFP) fluorescence in Gata2(GFP/+) mice that recapitulate endogenous GATA2 expression and found a robust GFP expression specifically in the renal medulla. (duke.edu)
  • We found that the Gata2-CKO mice showed a significant decrease in Aqp2 expression. (duke.edu)
  • Basic physiological data is available for both young (8 & 16 weeks) and aged (24-78 weeks) C57BL/6J mice on The Jackson Laboratory website. (jax.org)
  • The transcription factor GATA2 plays pivotal roles in early renal development, but its distribution and physiological functions in adult kidney are largely unknown. (duke.edu)
  • To address the physiological function of GATA2 in the CD cells, we generated renal tubular cell-specific Gata2-deficient mice (Gata2-CKO) by crossing Gata2 floxed mice with inducible Pax8-Cre mice. (duke.edu)
  • Phenotypic variability among inbred littermates reared in controlled environments remains poorly understood. (researchgate.net)
  • Weight increases with age but also shows increased variability in older mice. (jax.org)
  • As shown in Figure 1, aged B6J mice have greater variability than younger B6J mice. (jax.org)
  • Understanding the normal variability in the mice that you are working with is critical to perform statistically rigorous studies. (jax.org)
  • Due to a developmental switch during B cell ontogeny, autoreactive anti-hen egg lysozyme MD4 Ig transgene B cells are negatively selected by self-Ags in adult bone marrow but susceptible to positive selection by some of the same self-Ags in fetal and neonatal life. (ox.ac.uk)
  • In the fetal mouse brain, Cyp19a1 mRNA levels are inversely correlated with estrogen receptor alpha (Esr1) mRNA levels in a temporal manner. (nel.edu)
  • We also observed that in vitro treatment of blood with 3-PBA-albumin resulted in the activation of B- and T-helper lymphocytes and that these immune cells were also increased in blood of PB + PER exposed mice and veterans with GWI. (nih.gov)
  • Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. (ox.ac.uk)
  • Invariant NKT cells in adrenoleukodystrophy patients and mice. (ox.ac.uk)
  • However, the persistence of B1 cells and IgM autoantibodies from early ontogeny enables autoreactive B cells from the adult bone marrow to escape negative selection. (ox.ac.uk)
  • First, we monitored eating-associated dynamics of OH cells using fiber photometry in free-feeding mice. (elsevierpure.com)
  • We found that critically short telomeres altered retrotransposon activity to promote genomic instability in mouse embryonic stem cells, as evidenced by elevated numbers of single nucleotide variants, indels and copy number variations (CNVs). (nature.com)
  • They can also be activated during replicative senescence in mouse and human cells 20 . (nature.com)
  • Cells with astroglial characteristics are known to serve as progenitor cells in the developing and adult brain. (princeton.edu)
  • Despite such a significant decrease in ER-alpha immunoreactive and total cells, both young and middle age mice maintain a similar ratio of ER-alpha IR cells to total cells in the ARC hypothalamus. (nel.edu)
  • To test this hypothesis, we inoculated strain-typing panels of wild-type mice with brain material from human vCJD case-patients from France, the Netherlands, Italy, and the United States. (ox.ac.uk)
  • However, differences in incubation times require further subpassage in mice to establish any true differences in strain properties between cases. (ox.ac.uk)
  • 150 one-cell embryos from the C57BL/6J strain background or an alternative background as the project necessitates. (fredhutch.org)
  • We perform mouse strain rederivation to eliminate adventitious agents when they are identified during quarantine or routine murine health surveillance or as requested by researchers. (fredhutch.org)
  • The similarity strain-typing panels of wild-type mice with brain material from between BSE and vCJD was shown by experimental human vCJD case-patients from France, the Netherlands, transmission of the 2 diseases into standard panels of Italy, and the United States. (cdc.gov)
  • The strain properties of vCJD and BSE have been occurred from each sample tested, and data were similar extensively characterized in these sets of mice by using between non-UK and UK cases, with the exception of the a combination of the order in which each strain of mouse ranking of mean clinical incubation times of mouse lines. (cdc.gov)
  • Variant Creutzfeldt-Jakob disease (vCJD) is an acquired strain in the RIII, C57BL, and VM mice, whereas in the transmissible spongiform encephalopathy (TSE), FVB mice, both diseases exhibit the same pattern of PrPSc or prion disease, that results in a fatal neurodegenerative deposition ( 3-5 ). (cdc.gov)
  • The strain properties of vCJD and BSE have been extensively characterized in these sets of mice by using a combination of the order in which each strain of mouse dies of disease (incubation period rankings), distribution of brain vacuolation at the terminal stage of disease (lesion profiles), distribution pattern of abnormal prion protein (PrP Sc ) in the brain, and glycosylation pattern of PrP Sc as assessed by Western blot analysis. (cdc.gov)
  • BSE and vCJD produce highly reproducible and similar incubation period rankings and neuropathology, which indicates that they are the same strain in the RIII, C57BL, and VM mice, whereas in the FVB mice, both diseases exhibit the same pattern of PrP Sc deposition ( 3 - 5 ). (cdc.gov)
  • 2019. DNA methylation in mice is influenced by genetics as well as sex and life experience. (nih.gov)
  • Travel or movement may affect the physiology of the mice - and if you start taking measurements on the day of arrival your data may not be reflective of what is the normal variation in your facility. (jax.org)
  • Despite having high insulin levels, Tlr3(-/-) mice did not experience disturbances in whole-body insulin sensitivity, suggesting that they have a robust metabolic system that manages increased insulin secretion. (ox.ac.uk)
  • 2017. NTP Research Report on Baseline Characteristics of Diversity Outbred (J:DO) Mice Relevant to Toxicology Studies . (nih.gov)
  • The adventitious pathogen status of a transgenic mouse line may impact breeding efficiency, health and life span and experimental variables such as immune response or microbiota. (fredhutch.org)
  • Whole genome resequencing of two mice from the colony identified very few differences and these did not occur at or near the iiDMRs. (researchgate.net)
  • When the amount of non-rapid eye movement (NREM) sleep, rapid eye movement (REM) sleep and wakefulness were averaged over the dark period after SDS, only KO mice showed significant differences in NREM sleep and wakefulness. (tokushima-u.ac.jp)
  • However, differences in incubation times require further (PrPSc) in the brain, and glycosylation pattern of PrPSc as subpassage in mice to establish any true differences in assessed by Western blot analysis. (cdc.gov)
  • Our team transfers two-cell-stage embryos to pseudo-pregnant recipient mice the following day (~25 embryos per recipient). (fredhutch.org)
  • If a mouse survives a SeV infection, it develops a lifelong immunity to subsequent viral infections. (wikipedia.org)
  • Effect of HI-6 on cytokines production after immunity stimulation by keyhole limpet hemocyanin in a mouse model. (nel.edu)
  • In this review, we will concentrate on genome-wide approaches in mice, which have resulted in the identification of genes regulating anxiety. (biomedcentral.com)
  • Furthermore, because of the highly significant homologies in gene order and chromosomal structure that exist between mouse and man, identification of the chromosomal location of a susceptibility gene in the mouse provides the basis for potentially localizing a homologous human gene. (medscape.com)
  • We observed the presence of 3-PBA and 3-PBA modified lysine of protein peptides in the brain, blood and liver of pyridostigmine bromide (PB) and PER (PB+PER) exposed mice at acute and chronic post-exposure timepoints. (nih.gov)
  • The hippocampus contains one of the few neurogenic niches within the adult brain-the subgranular zone of the dentate gyrus. (nih.gov)
  • Social stress alters sleep in FGF21-deficient mice, Brain Research Bulletin, Vol.191, 40-47, 2022. (tokushima-u.ac.jp)
  • Complete OH cell inactivation in adult brain induced a hitherto unrecognized overeating phenotype and caused overweight that was preventable by mild dieting. (elsevierpure.com)
  • Pregnant mice were sacrificed at gestational days 9, 11, 13, 15, 16, 19, 21 and the brain tissues of the fetuses were harvested along with five newborns at the age of postnatal day 2. (nel.edu)
  • As anxiety is an evolutionarily conserved response, mouse models can be used to carry out genome-wide searches for specific genes in a setting that controls for the environmental factors. (biomedcentral.com)
  • The advantage of mouse models is that the environmental factors can be controlled for, or specifically administered. (biomedcentral.com)
  • Chronic 3,6′-dithiothalidomide administration to an elderly symptomatic cohort of 3xTg-AD mice reduced multiple hallmark features of AD, including phosphorylated tau protein, APP, Aβ peptide and Aβ-plaque number along with deficits in memory function to levels present in younger adult cognitively unimpaired 3xTg-AD mice. (nih.gov)
  • Using an immunohistochemical technique, we examined the natural course of nephrin, Wilms' tumor-1 (WT1) and synaptopodin at 16.5 days of embryonic age (E16.5d) and E19.5d, 7 days of post-neonatal age (P7d) and P42d during renal development of mice. (go.jp)
  • It was shown that resistance to the lethal effects of Sendai virus in mice is genetically controlled and expressed through control of viral replication within the first 72 hours of infection. (wikipedia.org)
  • The current model implicates that the first lineage commitment step of adult pluripotent HSCs results in a strict separation into common lymphoid and common myeloid precursors. (ox.ac.uk)
  • We provide a four-phase CRISPR/Cas9 genome-editing service that allows researchers to acquire desired alleles (null, conditional, precisely mutated reporter or tagged alleles) in mice. (fredhutch.org)
  • The researchers used inbred mice to examine methylation, which is the addition of methyl groups onto DNA, in regions where the nucleotide cytosine is followed by a phosphate and the nucleotide guanine. (nih.gov)
  • The similarity between BSE and vCJD was shown by experimental transmission of the 2 diseases into standard panels of inbred wild-type mouse lines (RIII, C57BL, and VM [ 1 , 2 ]) and into FVB mice ( 3 ). (cdc.gov)
  • Our aim was to elucidate alterations of the vascular network organization, taking advantage of Flk1(GFP/+) crossed with mdx mice (model for human DMD where all blood vessels express green fluorescent protein) and functional repercussions using in vivo nuclear magnetic resonance, combining arterial spin-labeling imaging of perfusion, and (31)P-spectroscopy of phosphocreatine kinetics. (ox.ac.uk)
  • For example, inbred mice carrying the agouti viable yellow (A vy ) allele show a range of coat colours associated with different DNA methylation states at the locus. (researchgate.net)
  • Using whole genome bisulphite sequencing of DNA from the livers of five mice from the A vy colony, we searched for sites at which DNA methylation differed among the mice. (researchgate.net)
  • inbred wild-type mouse lines (RIII, C57BL, and VM [ 1 , 2 ]) results were compared with those for 2 reference vCJD and into FVB mice ( 3 ). (cdc.gov)
  • The present study tested the hypothesis that early and adult adversities cumulate to produce helplessness depending on the genotype (3-hit hypothesis of psychopathology). (uniroma1.it)
  • We discuss the implications of these findings in terms of B cell selection and the maintenance of self-tolerance during early and adult life. (ox.ac.uk)
  • In Japan intranasal Sendai virus-based SARS-CoV-2 vaccine was created and tested in a mouse model. (wikipedia.org)
  • Serum samples were obtained from the mouse model of NAFLD, as well as 50 patients with NAFLD and 50 healthy individuals, and EVs were extracted and verified. (ox.ac.uk)
  • Be sure to visit the Aged B6J mouse page help you learn more about your aged mouse model from JAX. (jax.org)
  • 2015. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. . (oregonstate.edu)
  • C57BL/6 mice are highly resistant to the virus, while DBA/2J mice are sensitive. (wikipedia.org)
  • Little is known about the molecular mechanism whereby infant mice are resistant to proteinuria. (go.jp)
  • Affinity maturation of antibodies requires integrity of the adult thym" by Mouhammed AbuAttieh MD, Diane Bender et al. (lvhn.org)
  • Affinity maturation of antibodies requires integrity of the adult thymus. (lvhn.org)
  • We then describe how several genes have been identified through genome-wide methods in mouse models and subsequently investigated in human anxiety disorder samples as candidate genes. (biomedcentral.com)
  • Structural and Functional Alterations of Skeletal Muscle Microvasculature in Dystrophin-Deficient mdx Mice. (ox.ac.uk)
  • We offer sperm cryopreservation services for effective mouse colony management. (fredhutch.org)