• Scholars@Duke publication: beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. (duke.edu)
  • We have identified a novel G protein-coupled receptor kinase-interacting protein, GIT1, that is a GTPase-activating protein (GAP) for the ADP ribosylation factor (ARF) family of small GTP-binding proteins. (duke.edu)
  • ADP-Ribosylation Factor 6 (ARF6) is a GTP-binding protein that functions as a regulator of cytoskeleton remodeling and endocytic recycling. (antibodyguide.com)
  • Wang C, Timmons CL, Shao Q, Kinlock BL, Turner TM, Iwamoto A, Zhang H, Liu H, Liu B. GB virus type C E2 protein inhibits human immunodeficiency virus type 1 Gag assembly by downregulating human ADP-ribosylation factor 1. (ucdenver.edu)
  • ADP-ribosylation factor-like protein 13B (ARL13B), also known as ADP-ribosylation factor-like protein 2-like 1 (ARL2L1), is a protein that in humans is encoded by the ARL13B gene. (nsjbio.com)
  • We show that the ubiquitous trafficking protein ADP Ribosylation Factor 1 (ARF1) and the hemocyte-specific endosomal regulator Asrij differentially regulate humoral immunity. (nih.gov)
  • Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. (nature.com)
  • MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al. (nih.gov)
  • Protein expression is influenced by many factors that may vary between experiments or laboratories. (genscript.com)
  • Moxetumomab pasudotox-tdfk internalization results in ADP-ribosylation of elongation factor 2, inhibition of protein synthesis, and apoptotic cell death. (geisinger.org)
  • Inhibition of the Adp-Glucose Pyrophosphorylase in Transgenic Potatoes Leads to Sugar-Storing Tubers and Influences Tuber Formation and Expression of Tuber Storage Protein Genes. (mpg.de)
  • By designing self-assembling polypeptides we test our knowledge of factors controlling protein folding and association. (lu.se)
  • ADP ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily. (wikipedia.org)
  • The small ADP ribosylation factor (Arf) GTP-binding proteins are major regulators of vesicle biogenesis in intracellular traffic. (wikipedia.org)
  • ADP-RIBOSYLATION FACTOR 1 is involved in regulating intracellular transport by modulating the interaction of coat proteins with organelle membranes in the early secretory pathway. (ucdenver.edu)
  • The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. (thermofisher.com)
  • ARF6 is an allosteric activator of cholera toxin catalytic subunit, an ADP-ribosyltransferase. (antibodyguide.com)
  • Isolation and Expression Analysis of Cdna Clones Encoding a Small and a Large Subunit of Adp-Glucose Pyrophosphorylase from Sugar-Beet. (mpg.de)
  • We followed up this analysis by showing that loss of cln5 alters the intracellular and extracellular amounts of proliferation repressors during growth and increases the extracellular amount of conditioned medium factor, which regulates cAMP signalling during the early stages of development. (frontiersin.org)
  • ADP-ribosylation is a reversible posttranslational modification mediated by poly-ADP-ribose polymerase (PARP). (elsevierpure.com)
  • Here, we report that transcription factor NFAT binds to and is ADP-ribosylated by PARP-1 in an activation-dependent manner. (elsevierpure.com)
  • Together, these results demonstrate that ADP-ribosylation mediated by PARP-1 provides a molecular switch to positively regulate NFAT-dependent cytokine gene transcription. (elsevierpure.com)
  • Poly-ADP-ribosylation is a post-translational modification catalyzed by PARP enzymes with roles in transcription and chromatin biology. (nature.com)
  • Ranibizumab is a recombinant humanized monoclonal antibody fragment which binds to and inhibits human vascular endothelial growth factor A (VEGF-A). Ranibizumab inhibits VEGF from binding to its receptors and thereby suppressing neovascularization and slowing vision loss. (geisinger.org)
  • We show here that the native M3 muscarinic receptor in 1321N1 cells and an epitope-tagged M3 receptor expressed in COS7 cells substantially utilize an ADP-ribosylation factor (ARF)-dependent route of PLD activation. (strath.ac.uk)
  • The results of recent studies demonstrate that ADP-ribosylation contributes to transcription regulation. (elsevierpure.com)
  • ADP-ribosylation factor 1 is a member of the human ARF gene family. (thermofisher.com)
  • ADP-Ribosylation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • Mechanistically, ADP-ribosylation increases NFAT DNA binding. (elsevierpure.com)
  • Notably, histone macroH2A1.1 senses PARP1 activation, transiently compacts chromatin, reduces the recruitment of DNA damage factor Ku70-Ku80 and alters γ-H2AX patterns, whereas the splice variant macroH2A1.2, which is deficient in poly-ADP-ribose binding, does not mediate chromatin rearrangements upon PARP1 activation. (nature.com)
  • The structure of the macroH2A1.1 macrodomain in complex with ADP-ribose establishes a poly-ADP-ribose cap-binding function and reveals conformational changes in the macrodomain upon ligand binding. (nature.com)
  • Hassa, P.O. & Hottiger, M.O. The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. (nature.com)
  • Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome. (nature.com)
  • This gene encodes a member of the ADP-ribosylation factor-like family. (nsjbio.com)
  • Liang, JO & Kornfeld, S 1998, ' Erratum: Comparative activity of ADP-ribosylation factor family members in the early steps of coated vesicle formation on rat liver Golgi membranes (Journal of Biological Chemistry (1997) 272 (4141-4148)) ', Journal of Biological Chemistry , vol. 273, no. 4, pp. 2488. (umn.edu)
  • ADP-ribosylation factor plays a significant role in the growth of Mucorales. (medscape.com)
  • Hassa, P.O., Haenni, S.S., Elser, M. & Hottiger, M.O. Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? (nature.com)
  • The availability of free energy is one of the factors that determine if a molecule will move across a membrane, the other being the permeability of the molecule in the lipid bilayer. (wikibooks.org)
  • A Truncated Version of an Adp-Glucose Pyrophosphorylase Promoter from Potato Specifies Guard Cell-Selective Expression in Transgenic Plants. (mpg.de)
  • Risk factors such as diabetic ketoacidosis and neutropenia are present in most cases. (medscape.com)
  • Conclusion: In conclusion, our study provides an appropriate and generalisable assessment of risk factors affecting infection and prognosis in patients with MDRB, contributing to improved early identification of patients at higher risk of infection and death, and appropriately guiding clinical management. (bvsalud.org)
  • This graph shows the total number of publications written about "ADP-Ribosylation Factor 1" by people in this website by year, and whether "ADP-Ribosylation Factor 1" was a major or minor topic of these publications. (ucdenver.edu)
  • One of 2 Different Adp-Glucose Pyrophosphorylase Genes from Potato Responds Strongly to Elevated Levels of Sucrose. (mpg.de)
  • Cox regression analysis identified respiratory failure, malnutrition, an APACHE II score of at least 20, and higher blood creatinine levels as independent prognostic risk factors. (bvsalud.org)
  • Immunocompromising conditions are the main risk factors for mucormycosis. (medscape.com)
  • older iron chelators such as deferoxamine and all causes of iron overload are additional risk factors for mucormycosis. (medscape.com)
  • Additionally, nonsterile tape and contaminated wooden splints are other risk factors for cutaneous diseases. (medscape.com)
  • Some patients with mucormycosis have no identifiable risk factors. (medscape.com)
  • Multifactorial regression analysis to identify risk factors associated with MDRB infection and prognosis. (bvsalud.org)
  • The relevant risks of each patient in the prognostic training cohort were scored based on prognostic independent risk factors. (bvsalud.org)
  • Finally, models were established based on independent risk factors for infection, risk groups, and independent prognostic factors, and were presented on nomograms. (bvsalud.org)
  • Multivariate analysis revealed that endotracheal intubation, previous antibiotic use beyond 2 weeks, and concurrent respiratory failure or cerebrovascular disease were independent risk factors associated with the incidence of MDRB infection. (bvsalud.org)
  • A diffusion coefficient is a factor of proportionality that represents the amount of substance diffusion across a unit area through a unit concentration gradient in unit time. (wikibooks.org)
  • Other high-risk groups include patients with cancer, especially those who are neutropenic and those receiving broad-spectrum antibiotics, and individuals receiving immunosuppressive agents, including oral or intravenous steroids and tumor necrosis factor (TNF)-alpha blockers (patients with rheumatoid disorders). (medscape.com)