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  • fetal
  • During the 2013 debate on the abortion restrictions bill, Davis offered an amendment to the abortion bill which retained the 20-week ban, but which deleted the unconstitutional facility restrictions, and instead incorporated exceptions for cases of rape, incest, danger to the mother's life and severe fetal abnormalities. (wikipedia.org)
  • arterial
  • Corneal uno azithromycin presentation with blood studies, canadian traumatic months, and/ormodafinil induces it arterial reaction 500 offender business via ratio many after main child. (espacerugby.com)
  • receptor
  • We are concentrating on hippocampal α7 and α4β2 nicotinic receptor subtypes and how they interact with dopamine D1 and D2, serotonin 5HT2, GABA and glutamate NMDA systems with regard to memory, attention and nicotine self-administration. (duke.edu)
  • EP4 is the major receptor associated with PGE2-induced dilation of the DA and can be found across the DA in smooth muscle cells. (wikipedia.org)
  • Drugs used to treat obesity are called anorectics and generally include drugs that follow the general definition of a stimulant, but other drugs such as CB1 receptor antagonists exist in this class too. (wikipedia.org)
  • Due to its hydrophilic character, IP3 can travel to the endoplasmic reticulum, where it induces, via fixation on its receptor, the opening of calcium channels increasing in this way the cytosolic calcium concentrations. (wikipedia.org)
  • dose
  • Both the risk of developing the syndrome and the likelihood that it will become irreversible are believed to increase as the duration of treatment and the total cumulative dose of neuroleptic drugs administered to the patient increase. (mentalhealth.com)
  • Methamphetamine is known to possess a high addiction liability (i.e., a high likelihood that long-term or high dose use will lead to compulsive drug use) and high dependence liability (i.e. a high likelihood that withdrawal symptoms will occur when methamphetamine use ceases). (wikipedia.org)
  • cocaine
  • Drugs such as ephedrine, pseudoephedrine, amphetamine and methylphenidate have well documented ergogenic effects, while drugs such as cocaine and methamphetamine have the opposite effect. (wikipedia.org)
  • dosage
  • CONCLUSIONS: Minimizing the risks of benzodiazepine therapy among pregnant or lactating women involves using drugs that have established safety records at the lowest dosage for the shortest possible duration, avoiding use during the first trimester, and avoiding multidrug regimens. (biomedsearch.com)
  • When serum level determinations are necessary, they should be obtained at least 5 to 7 half-lives after treatment initiation, dosage change, or addition or subtraction of another drug to the regimen so that equilibrium or steady-state will have been achieved. (drugs.com)
  • treatment
  • They will take the study drug once a day for 4 weeks followed by a 2 week rest period (no study drug treatment). (clinicaltrials.gov)
  • Subsequently, ibogaine and 18-methoxycoronaridine have been studied for the treatment of drug addiction. (drugs.com)
  • Phenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy. (drugs.com)
  • The GIDAC met to discuss Pfizer's supplemental New Drug Application (sNDA) for XELJANZ ® (tofacitinib), which is currently under review by the FDA, for the treatment of adult patients with moderately to severely active ulcerative colitis (UC). (enhancedonlinenews.com)
  • Building on his work, research both in China and the West eventually led to the development of the drug Trisenox by PolaRx Biopharmaceuticals, Inc through NDA, which was approved for leukemia treatment by the US FDA in 2000 and subsequently marketed and sold by Cell Therapeutics, Inc., before being acquired by Cephalon. (wikipedia.org)
  • The combination therapy of arsenic trioxide and all-trans retinoic acid (ATRA) has been approved by the U.S. Food and Drug Administration (FDA) for treatment of certain leukemias. (wikipedia.org)
  • Methamphetamine (contracted from N-methylamphetamine) is a strong central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. (wikipedia.org)
  • It is rarely prescribed due to concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy. (wikipedia.org)
  • efficacy
  • One clinical study in agitated elderly patients compared the effects of tiapride, haloperidol and placebo and found that while the two drugs had comparable efficacy superior to the placebo effect, tiapride had fewer and less severe side effects than haloperidol. (wikipedia.org)
  • However
  • However, serum drug levels are not useful for evaluating risk of arrhythmia or seizure in tricyclic overdose. (wikipedia.org)
  • include
  • Potentially serious side effects include electrolyte abnormalities, low blood pressure, and hearing loss. (wikipedia.org)
  • Visual abnormalities may conflict with proprioceptive information, and visions may include experiences such as the ground tilting. (wikipedia.org)
  • Drugs used to treat sleep disorders such as excessive daytime sleepiness are called eugeroics and include notable stimulants such as modafinil. (wikipedia.org)
  • full citation needed] Recent evidence suggests[weasel words] that deleterious GTN-induced production of oxygen free radicals might induce a number of abnormalities, include those described above, so that the oxidative stress hypothesis might represent a unifying principle. (wikipedia.org)
  • disorders
  • The ever-increasing hypersensitivity disorders, multiple chemical sensitivities, and allergies or immune reactions to drugs, foods, toxins and radiation of various kinds form a related group of disorders. (homeopathicassociates.com)
  • Interestingly, most conventional medical practice appears to have very little interest in investigating medically induced causes of disorders and finding ways to remove them. (homeopathicassociates.com)
  • methamphetamine
  • While dextromethamphetamine is a more potent drug, racemic methamphetamine is sometimes illicitly produced due to the relative ease of synthesis and limited availability of chemical precursors. (wikipedia.org)
  • As methamphetamine is associated with a high potential for misuse, the drug is regulated under the Controlled Substances Act and is listed under Schedule II in the United States. (wikipedia.org)
  • discontinuation
  • The MVI 200 will be kept in place for up to 24 hours or will be removed earlier if one of the following occur: onset of active labor, intrapartum adverse event necessitating discontinuation of the study drug, other reasons including maternal request. (clinicaltrials.gov)
  • involves
  • Content frequently involves animate objects, although perceptual abnormalities such as changes in lighting, shading, streaks, or lines may be seen. (wikipedia.org)
  • Patients
  • It is also contraindicated in patients with suspected or established subcortical brain damage, with or without hypothalamic damage, since a hyperthermic reaction with temperatures in excess of 40°C may occur in such patients, sometimes not until 14 to 16 hours after drug administration. (mentalhealth.com)
  • for randomized patients who did not receive study drug, the period ends 14 days after randomization.Venous thromboembolic event (VTE)=nonfatal pulmonary embolism (PE), symptomatic deep vein thrombosis (DVT), or asymptomatic proximal DVT detected by ultrasound. (clinicaltrials.gov)
  • Moxifloxacin should also be avoided in patients with uncorrected hypokalemia, or concurrent administration of other medications known to prolong the QT interval (antipsychotics and tricyclic antidepressants). (wikipedia.org)
  • symptoms
  • While tiapride does not affect positive symptoms of psychosis such as hallucinosis or delirium sometimes manifested in alcohol withdrawal syndrome, if combined with a drug such as carbamazepine that addresses those symptoms, it is ideal for treating alcohol dependency because its metabolism does not depend on liver function and it has low potential for abuse. (wikipedia.org)
  • widely
  • Historically, pharmacological, or drug-induced models were the most widely used. (wikipedia.org)
  • Stimulants are widely used throughout the world as prescription medicines as well as without a prescription (either legally or illicitly) as performance-enhancing or recreational drugs. (wikipedia.org)
  • risk
  • A significant number of drugs found within this class, including moxifloxacin, are not licensed by the FDA for use in children due to the risk of permanent injury to the musculoskeletal system. (wikipedia.org)
  • dopamine
  • Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. (wikipedia.org)
  • Low blood pressure is initially treated with fluids along with bicarbonate to reverse metabolic acidosis (if present), if the blood pressure remains low despite fluids then further measures such as the administration of epinephrine, norepinephrine, or dopamine can be used to increase blood pressure. (wikipedia.org)
  • interference
  • In 2011, Davis voted against a bill to require physicians to conduct intra-vaginal sonograms, prior to even pharmaceutically induced abortions, citing her opposition to legislative interference in the doctor-patient relationship. (wikipedia.org)
  • effects
  • In addition, ibogaine is stored in fat and a slow release from fat stores has been hypothesized to further contribute to the protracted effects of the drug. (drugs.com)
  • Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects. (wikipedia.org)
  • Neurocognitive enhancing effects of stimulants, specifically modafinil, amphetamine and methylphenidate have been documented in healthy adolescents, and is a commonly cited reason among illicit drug users for use, particularly among college students in the context of studying. (wikipedia.org)
  • nasal
  • Levomethamphetamine is available as an over-the-counter (OTC) drug for use as an inhaled nasal decongestant in the United States. (wikipedia.org)
  • selective
  • LY-341,495 and MGS-0039 are drugs that act as a selective antagonist blocking both of the group II metabotropic glutamate receptors, mGluR2 and mGluR3. (wikipedia.org)
  • production
  • Congenital adrenal hyperplasia (CAH) is an inherited disorder that leads to insufficient production of cortisol caused by abnormality in 1 of the 5 enzymes that are necessary for its biosynthesis. (aappublications.org)
  • blood
  • The 10 hour and 14 hour blood samples were obtained if the subject still had the study drug in place at those timepoints. (clinicaltrials.gov)
  • females
  • In age effect studies we have shown that adolescents self-administer greater amounts of nicotine than adults and that particularly in females greater adolescent-onset of nicotine self-administration continues into adulthood. (duke.edu)
  • Persistence of the ductus may be associated with other abnormalities, and is much more common in females. (wikipedia.org)
  • long-term
  • Using knockout mice, we have found that β2-containinc nicotinic receptors appear to be more important for the initiation of nicotine self-administration during the first few weeks, whereas α7 nicotinic receptors appear to be more important for the long-term consumption of nicotine over a period of 5 months. (duke.edu)
  • 6 This effect might be caused by the long-term administration of corticosteroids or the excessive secretion of adrenocorticotropic hormone. (aappublications.org)
  • study drug
  • Participants will take the study drug, sunitinib, for 7 days prior to their surgery. (clinicaltrials.gov)
  • Time of Maximum Plasma Concentration (Tmax) of Misoprostol After Insertion [ Time Frame: From study drug insertion up to 1 hour post study drug removal. (clinicaltrials.gov)
  • All adverse events were rated by the Investigator as mild, moderate or severe and classified as having no relationship, possible relationship or a probable relationship to the study drug. (clinicaltrials.gov)