• cell adhesive
  • To determine the potential involvement of Periaxin (Prx), a PDZ domain containing protein, in regulation of N-cadherin/Catenin-based cell adhesive interactions in lens fibers. (arvojournals.org)
  • The integrity of N-cadherin and αN-catenin-based cell adhesive interactions in the absence of Prx was determined using Prx null mouse lenses. (arvojournals.org)
  • The coimmunoprecipitation of αN-catenin with Prx and AnkB, in coexistence of αN-catenin with N-cadherin, β-catenin, Prx and AnkB in membrane rafts , and impairment of αN-catenin membrane localization in the absence of Prx in lens fibers, collectively suggests a crucial role for Prx in formation and stabilization of N-cadherin/αN-catenin-based cell adhesive interactions. (arvojournals.org)
  • Application of reductive potential also corresponded to switching of ITO electrode properties from cell non-adhesive to cell-adhesive. (jove.com)
  • 1992
  • but each of these proteins has subsequently been shown to have a much broader tissue distribution ( Geiger and Ayalon, 1992 ). (jneurosci.org)
  • indicate
  • These findings indicate that N-cadherin adhesion may stabilize early synapses that can then be remodeled to express a different cadherin and that cadherins systematically differentiate between functionally (excitatory and inhibitory) and spatially distinct synaptic sites on single neurons. (jneurosci.org)
  • cellular
  • The ability to exercise precise spatial and temporal control over cell-surface interactions is an important prerequisite to the assembly of multi-cellular constructs serving as in vitro mimics of native tissues. (jove.com)
  • Electrochemical stripping of PEG-silane layer from ITO microelectrodes allowed for cell adhesion to take place in a spatially defined fashion, with cellular patterns corresponding closely to electrode patterns. (jove.com)
  • Stimuli that disrupt cell-matrix adhesion ( e.g. , myeloperoxidase and other matrix-modifying oxidants/enzymes released during inflammation) are implicated in triggering pathological changes in cellular function, phenotype and viability in a number of diseases. (jove.com)
  • Both techniques accurately quantify rapid changes to cellular adhesion and de-adhesion processes. (jove.com)
  • These approaches are also applicable for studying cellular adhesion dynamics in response to other matrix-modifying stimuli and in related adherent cells ( e.g., epithelial cells). (jove.com)
  • Method
  • A method of microdissection which involves: forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones. (google.com)
  • material
  • Microelectrode arrays for neural interface devices that are made of biocompatible thin-film polymer are expected to have extended functional lifetime because the flexible material may minimize adverse tissue response caused by micromotion. (jove.com)
  • response
  • We hypothesized that the persistence of the nanomaterial in the tissue can induce an antioxidant response that might have provided resistance to an initial insult. (jove.com)
  • transfer
  • The extraction is achieved by contacting the tissue sample with a transfer surface that can be selectively activated so that regions thereof adhere to the zone of cells of interest to be extracted. (google.com)
  • After the transfer surface is activated the transfer surface and tissue sample are separated. (google.com)
  • During separation the zone of cells of interest remains adhered to the transfer surface and is thus separated from the tissue sample. (google.com)
  • tissue sample absent from the transfer surface at regions which are not activated by electromagnetic radiation. (google.com)