• spores
  • In this work, we characterized the adherence properties of epidemic R20291 spores to components of the intestinal mucosa, and we assessed the role of the exosporium integrity in the adherence properties by using cdeC mutant spores with a defective exosporium layer. (frontiersin.org)
  • Our results showed that spores and vegetative cells of the epidemic R20291 strain adhered at high levels to monolayers of Caco-2 cells and mucin. (frontiersin.org)
  • Transmission electron micrographs of Caco-2 cells demonstrated that the hair-like projections on the surface of R20291 spores are in close proximity with the plasma membrane and microvilli of undifferentiated and differentiated monolayers of Caco-2 cells. (frontiersin.org)
  • Recently there has been a focus on adding a germination step during decontamination strategies to achieve better disinfection since vegetative cells are much easier to kill than spores (39, 40, 43). (lsu.edu)
  • virulence
  • In addition to classical V. parahaemolyticus TDH and TRH virulence factors, O3:K6 exhibited specific genetic markers as toxRS/New and orf8 [2, (scielo.cl)
  • The most characteris-tic features of C. albicans are its extraordinary range of virulence factors, particularly adherence and spread on and/or through epithelial and endothelial tissues by inducing the filamentous growth and hyphal-associated aspartic proteases (Saps). (pjmonline.org)
  • Adherence to host tissues and morphological versatility are thought to be important in C. albicans virulence (Bertini et al . (pjmonline.org)
  • Several genes isolated from resistant enterococci ( agg, gelE, ace, cylLLS, esp, cpd, fsrB ) encode virulence factors such as the production of gelatinase and hemolysin, adherence to caco-2 and hep-2 cells, and capacity for biofilm formation. (medscape.com)
  • Microbiology
  • D. Bradley, B. McNeil, J. G. Laffey, and N. J. Rowan, "Studies on the pathogenesis and survival of different culture forms of Listeria monocytogenes to pulsed UV-light irradiation after exposure to mild-food processing stresses," Food Microbiology , vol. 30, no. 2, pp. 330-339, 2012. (hindawi.com)
  • bacterial
  • Resistance of E faecalis and E faecium to daptomycin, a newer cyclic lipopeptide antibiotic that acts on the bacterial cell membrane, has also been reported. (medscape.com)
  • EHEC
  • We sought to identify genes involved in the control of adherence of EHEC O157:H7 to cultured epithelial cells. (asm.org)
  • Our results indicate that multiple elements control adherence and OmpA acts as an adhesin in EHEC O157:H7. (asm.org)
  • In the case of EHEC serotype O157:H7, very little is known about potential additional factors associated with adherence. (asm.org)
  • It is challenging to determine why, from the multiple regions in the EHEC O157:H7 chromosome with a putative role in adherence, only a limited number of genes within the LEE and other loci have been suggested to be involved in the adherence of these organisms to host cells. (asm.org)
  • In EPEC, perC is known to be part of the per operon, along with perA and perB , located on the EPEC adherence factor plasmid, which is not found in EHEC. (microbiologyresearch.org)
  • Concentrations
  • The results of the current study suggested that low concentrations of DON commonly detected in food may either limit or sustain the proliferation of colon cancer cells, depending on their proliferation status and on DON concentration. (mdpi.com)
  • gene
  • Leukotriene B4 receptor 2, also known as BLT2, BLT2 receptor, and BLTR2, is a Integral membrane protein that is encoded by the LTB4R2 gene in humans and the Ltbr2 gene in mice. (wikipedia.org)
  • species
  • Exposure of proliferating Caco-2 cells to silver nanoparticle induced decreasing adherence capacity and cytotoxicity, whereby the formation of reactive oxygen species could be the mode of action. (biomedsearch.com)
  • One prominent cell-activating pathway involves BLT2 receptor activation of NOX2 or NOX1 with the subsequent production of reactive oxygen species which in turn activate the transcription inducing function of NF-κB. (wikipedia.org)
  • membrane
  • The Gram-positive cell envelope consists of two main layers, the cytoplasmic membrane and peptidoglycan (or cell wall). (biomedcentral.com)
  • In addition, an outer membrane protein, multivalent adhesion molecule (MAM) which includes MCE (from Mammalian cell entry domains) was recently described in V. parahaemolyticus [5, (scielo.cl)
  • surface
  • BLT2 is a Cell surface receptor that functions by recognizing, binding, and mediating responses to a particular set of messenger molecules or ligands. (wikipedia.org)
  • responses
  • These messenger ligands are any one of a range of structurally different arachidonic acid metabolites made and released by nearby cells to act as paracrine signals for coordinating responses between cells or autocrine signals for modulating their parent cells' responses. (wikipedia.org)
  • peptide
  • The secreted aspartic protease (Sap) family encompasses at least ten mem-bers (Saps1-10) containing a signal peptide, which are secreted, except for Sap9 and Sap10 that remain bound to the cell wall. (pjmonline.org)
  • Activity
  • Combining a cell wall-active agent such as ampicillin or vancomycin with an aminoglycoside may result in synergistic bactericidal activity against enterococci. (medscape.com)
  • data
  • [2] According to National Nosocomial Infections Surveillance (NNIS) data from January 2003 through December 2003, more than 28% of enterococcal isolates in ICUs of the more than 300 participating hospitals were vancomycin-resistant. (medscape.com)
  • ability
  • In the laboratory, enterococci are distinguished by their morphologic appearance on Gram stain and culture (gram-positive cocci that grow in chains) and their ability to (1) hydrolyze esculin in the presence of bile, (2) their growth in 6.5% sodium chloride, (3) their hydrolysis of pyrrolidonyl arylamidase and leucine aminopeptidase, and (4) their reaction with group D antiserum. (medscape.com)