• clinical
  • Cushing's syndrome is a clinical condition resulting from excessive levels of circulating glucocorticoids and can be caused by adrenocortical adenomas. (oncologynurseadvisor.com)
  • The work-up for adrenal adenomas usually results from one of two clinical scenarios. (oncologynurseadvisor.com)
  • The second clinical scenario where work-up of an adrenal adenoma is indicated is after identification of a clinical syndrome that is suggestive of adrenal hyperfunction. (oncologynurseadvisor.com)
  • Some adenomas are too small to be seen macroscopically but can still cause clinical symptoms. (wikipedia.org)
  • Peeker R Aldenborg F Fall M: Nephrogenic adenoma: A study with special reference to clinical presentation. (wikipedia.org)
  • Very occasionally, a true adrenal cortical adenoma is associated with the clinical manifestations of Conn's syndrome, and can be shown to be excreting mineralocorticoids. (wikipedia.org)
  • epithelial
  • Some adenomas grow from epithelial tissue in nonglandular areas but express glandular tissue structure (as can happen in familial polyposis coli). (wikipedia.org)
  • Nipple adenomas usually have a rounded outline at low magnification, and at higher magnification can be seen to consist of a haphazardly arranged mass of proliferating tubular structures composed of epithelial and myoepithelial cells within varying amounts of fibrous stroma. (wikipedia.org)
  • Being an adenoma, the mass is covered in columnar epithelial cells. (wikipedia.org)
  • follicular
  • Almost all thyroid adenomas are follicular adenomas. (wikipedia.org)
  • Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function. (wikipedia.org)
  • Histopathologically, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types: Fetal (microfollicular) - these have the potential for microinvasion. (wikipedia.org)
  • Thyroid follicular adenoma ranges in diameter from 3 cm on an average, but sometimes is larger (up to 10 cm) or smaller. (wikipedia.org)
  • Areas of hemorrhage, fibrosis, calcification, and cystic change, similar to what is found in multinodular goiters, are common in thyroid (follicular) adenoma, particularly in larger lesions. (wikipedia.org)
  • Diagnosis
  • The major diagnosis from which to separate ceruminous adenoma is ceruminous adenocarcinoma, which shows an infiltrative growth, pleomorphism, mitoses, necrosis, and lacks ceroid pigment granules. (wikipedia.org)
  • parathyroid hormone
  • When a parathyroid adenoma causes hyperparathyroidism, more parathyroid hormone is secreted, causing the calcium concentration of the blood to rise, resulting in hypercalcemia. (wikipedia.org)
  • typically
  • A thyroid adenoma is distinguished from a multinodular goiter of the thyroid in that an adenoma is typically solitary, and is a neoplasm resulting from a genetic mutation (or other genetic abnormality) in a single precursor cell. (wikipedia.org)
  • lesion
  • The typical thyroid adenoma is solitary, spherical and encapsulated lesion that is well demarcated from the surrounding parenchyma. (wikipedia.org)
  • Conn's
  • While some adrenal adenomas do not secrete hormones at all, often some secrete cortisol, causing Cushing's syndrome, aldosterone causing Conn's syndrome, or androgens causing hyperandrogenism. (wikipedia.org)
  • incidence
  • Incidence of adenomas may be increased in metabolic diseases, including tyrosinemia and type 1 diabetes mellitus, and glycogen storage diseases (types 1 and 3), as well as in beta-thalassemia and hemochromatosis. (wikipedia.org)
  • distinguish
  • Though no definitive test can distinguish between adenoma and malignancy, imaging is the most useful modality, with computed tomography (CT) being the preferred imaging test. (oncologynurseadvisor.com)
  • Lesions
  • Lesions of the nipple and areola, such as nipple adenoma, may be difficult to image clearly on routine mammogram or ultrasonography. (wikipedia.org)
  • cortex
  • The primary hormone found in excess, as many adenomas arise from a discrete zone of the adrenal cortex and may overproduce a single hormone, delineates these syndromes. (oncologynurseadvisor.com)