Genes, RecessiveAdaptor Proteins, Signal TransducingAdaptor Proteins, Vesicular TransportGRB2 Adaptor ProteinShc Signaling Adaptor ProteinsAdaptor Protein Complex 2Adaptor Protein Complex 3Adaptor Protein Complex 1Molecular Sequence DataGRB10 Adaptor Proteinsrc Homology DomainsAdaptor Protein Complex alpha SubunitsAmino Acid SequenceSignal TransductionAdaptor Protein Complex beta SubunitsMutationBase SequenceCarrier ProteinsAdaptor Protein Complex mu SubunitsProtein BindingProto-Oncogene Proteins c-crkAdaptor Protein Complex 4PhosphoproteinsProteinsAdaptor Protein Complex gamma SubunitsMembrane ProteinsClathrinPhosphorylationAdaptor Protein Complex SubunitsCell LineProtein Structure, TertiaryConsanguinityAdaptor Protein Complex delta SubunitsPedigreeMyeloid Differentiation Factor 88CRADD Signaling Adaptor ProteinCloning, MolecularTyrosineSequence Homology, Amino AcidIntracellular Signaling Peptides and ProteinsRecombinant Fusion ProteinsProtein TransportAmino Acid MotifsEndocytosisGRB7 Adaptor ProteinPhenotypeMice, KnockoutHomozygoteRibosomal ProteinsNerve Tissue ProteinsTransfectionTwo-Hybrid System TechniquesBinding SitesGene Expression RegulationChromosome MappingCOS CellsAdaptor Protein Complex sigma SubunitsOncogene ProteinsCrk-Associated Substrate ProteinProto-Oncogene Proteins c-cblClathrin-Coated VesiclesCytoskeletal ProteinsSequence AlignmentRNA, MessengerImmunoprecipitationNuclear ProteinsCells, CulturedJurkat CellsTranscription, GeneticProtein-Tyrosine KinasesReceptors, Interleukin-1Monomeric Clathrin Assembly ProteinsUbiquitin ThiolesteraseGenes, DominantHeLa CellsSon of Sevenless ProteinsMice, Inbred C57BLDNA-Binding ProteinsDNA Mutational AnalysisPhosphotyrosineCARD Signaling Adaptor ProteinsGenetic LinkageAllelesEndosomesDNA PrimersMembrane GlycoproteinsTranscription FactorsModels, BiologicalSequence Analysis, DNAHEK293 CellsPrecipitin TestsMutation, MissenseEnzyme Activationtrans-Golgi NetworkPromoter Regions, GeneticPolymerase Chain ReactionBlotting, WesternDNA, ComplementaryProto-Oncogene ProteinsPhospholipase C gamma