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  • vaccines
  • Significant barriers exist to the development of effective vaccines that induce protection against the lentiviruses that cause severe disease in both humans and animals. (pubmedcentralcanada.ca)
  • Modified live vaccines are efficacious against numerous viral diseases, but concern over reversion to a virulent phenotype or recombination with endogenous or exogenous viruses have limited their use against lentiviruses ( 8 ). (pubmedcentralcanada.ca)
  • Synthetic peptide vaccines have numerous advantages including the inclusion of only defined epitopes to generate relevant immune responses rather than a broad response that may exacerbate infectivity and disease ( 4 , 23 , 29 , 48 ). (pubmedcentralcanada.ca)
  • results
  • A negative result does not negate the presence of the organism or active disease, as false-negative results may occur due to inhibition of PCR, sequence variability underlying the primers and probes, or the presence of Coxiella burnetii in quantities less than the limit of detection of the assay. (mayomedicallaboratories.com)
  • COPD
  • Under specific paraphysiological conditions such as senescence or chronic/acute diseases such as heart failure, diabetes , COPD, stroke, sepsis and trauma , the rate of protein catabolism is high with serious impairment of protein metabolism, which correlates with morbidity and mortality [ 2 , 3 ]. (omicsonline.org)
  • Acute exacerbation of COPD also known as acute exacerbations of chronic bronchitis (AECB) is a sudden worsening of COPD symptoms (shortness of breath, quantity and color of phlegm) that typically lasts for several days. (wikipedia.org)
  • An acute exacerbation of COPD is associated with increased frequency and severity of coughing. (wikipedia.org)
  • As the lungs tend to be vulnerable organs due to their exposure to harmful particles in the air, several things can cause an acute exacerbation of COPD: Respiratory infection, being responsible for approximately half of COPD exacerbations. (wikipedia.org)
  • Risk factors include other lung diseases such as cystic fibrosis, COPD, and asthma, diabetes, heart failure, a history of smoking, a poor ability to cough such as following a stroke, or a weak immune system. (wikipedia.org)
  • severe
  • Acute disease often presents with sudden severe pain. (wikipedia.org)
  • He writes of a disease coming from Ethiopia and passing through Egypt and Libya into the Greek world-a plague so severe and deadly that no one could recall anywhere its like, and physicians ignorant of its nature not only were helpless but themselves died the fastest, having had the most contact with the sick. (wikipedia.org)
  • Fever is not very specific, as it occurs in many other common illnesses, may be absent in those with severe disease, malnutrition or in the elderly. (wikipedia.org)
  • diagnosis
  • Todd was a popular lecturer, and was noted for his accuracy in the observation of disease, correctness of diagnosis, and clarity and exactness in expressing his views. (wikipedia.org)
  • affects
  • Acute flaccid myelitis is a rare condition that affects the area of spinal cord called gray matter and can cause paralysis. (usatoday.com)
  • It is usually remain in soil.But, affects man and animal both.In man it produces disease. (myshared.ru)
  • A disease is a particular abnormal condition that affects part or all of an organism not caused by external force (see 'injury') and that consists of a disorder of a structure or function, usually serving as an evolutionary disadvantage. (wikipedia.org)
  • surveillance
  • Identify and respond to emerging infectious disease threats by building surveillance systems. (georgia.gov)
  • Some surveillance teams may specialize in groups of diseases that are related to each other in a specific way, while others are specific to a particular type of disease. (georgia.gov)
  • symptoms
  • Disease is often construed as a medical condition associated with specific symptoms and signs. (wikipedia.org)
  • By contrast, an infection that is asymptomatic during its incubation period, but expected to produce symptoms later, is usually considered a disease. (wikipedia.org)
  • diabetes
  • As medical science has advanced, many diseases whose causes were formerly complete mysteries have been somewhat explained (for example, when it was realized that autoimmunity is the cause of some forms of diabetes mellitus type 1, even if we do not yet understand every molecular detail involved) or even extensively explained (for example, when it was realized that gastric ulcers are often associated with Helicobacter pylori infection). (wikipedia.org)
  • epidemic
  • In his History of the Peloponnesian War the historian Thucydides, who was present and contracted the disease himself and survived, describes the epidemic. (wikipedia.org)
  • Commonly
  • Pneumonia is usually caused by infection with viruses or bacteria and less commonly by other microorganisms, certain medications and conditions such as autoimmune diseases. (wikipedia.org)
  • Bloody sputum (known as hemoptysis) may also occur with tuberculosis, Gram-negative pneumonia, and lung abscesses as well as more commonly with acute bronchitis. (wikipedia.org)
  • outbreaks
  • Provide support to local and district public health and private partners in identifying training and resource needs, developing guidelines for and investigating outbreaks or increases in endemic rates of disease, developing educational and training materials, and collecting and disseminating data. (georgia.gov)
  • CADE routinely monitors over 45 diseases as well as unusual occurrences of disease (outbreaks). (iowa.gov)
  • patients
  • Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation. (clinicaltrials.gov)
  • Both past and recent data show that protein metabolic impairment are present in about 45% of elderly patients hospitalised from a variety of chronic diseases and in peculiar in chronic heart failure patients [ 2 ]. (omicsonline.org)
  • Condition
  • In humans, disease is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person afflicted, or similar problems for those in contact with the person. (wikipedia.org)
  • Disease The term disease broadly refers to any condition that impairs the normal functioning of the body. (wikipedia.org)
  • several
  • Quinton Hill, 7, from Lakeville, Minn., is one of several children in the state diagnosed with acute flaccid myelitis, a polio-like disorder that can cause paralysis. (usatoday.com)
  • health
  • to the magazine of INHS , a non-profit organisation for discussing & teaching Natural Hygiene , a scientific view on health and disease with roots as far back as 1822. (naturalhygienesociety.org)
  • According to the Minnesota Department of Health, the six cases have been classified as Acute flaccid myelitis and were reported in children under 10 years old. (usatoday.com)
  • The disease may be classified by where it was acquired with community, hospital, or health care associated pneumonia. (wikipedia.org)
  • Review
  • In this review, we compare and analyze all kinds of mitochondrion-permeable antioxidants, including edaravone, idebenone, α -Lipoic acid, carotenoids, vitamin E, and coenzyme Q10, and mitochondria-targeted antioxidants MitoQ and SkQ and propose astaxanthin (a special carotenoid) to be the best antioxidant for ROS-burst-mediated acute diseases, like avian influenza infection and ischemia-reperfusion. (hindawi.com)
  • A 54-year-old lady was diagnosed with left Meniere's disease who during her regular clinic review suffers an acute attack of vertigo, with fullness and an increase of tinnitus in her left ear. (cun.es)
  • people
  • People in 22 states were diagnosed with this rare polio-like disease. (usatoday.com)
  • Diseases can affect people not only physically, but also emotionally, as contracting and living with a disease can alter the affected person's perspective on life. (wikipedia.org)
  • known
  • The impact of disease on social and religious behavior was also documented during the worldwide pandemic best known as the Black Death. (wikipedia.org)
  • Among his many achievements was the discovery of a disease, Sydenham's Chorea, also known as St Vitus Dance. (wikipedia.org)
  • work
  • The work, Regimen in Acute Diseases, attributed to the ancient Greek physician, Hippocrates of Cos, describes the types and usage of medical regimens in his era (400 BCE). (wikipedia.org)
  • characterized by Th2 cy
  • Acute exposure of sensitized mice to antigen elicits allergic airway disease (AAD) characterized by Th2 cytokine-dependent pulmonary eosinophilia, methacholine hyperresponsiveness and antigen-specific IgE elevation. (uconn.edu)
  • Centers for Dis
  • The U.S. Centers for Disease Control and Prevention's National Center for Injury Prevention and Control's mission is to provide leadership in preventing and controlling injuries, i.e., reducing the incidence, severity, and adverse outcomes of injury, the leading cause of death for those aged 1 - 44. (wikipedia.org)
  • Syndrome
  • Acute neck pain can occur from calcifications around the odontoid process ("Crowned dens syndrome", which can be composed of apatite, CPP crystals, or both). (psychiatryadvisor.com)
  • 427.8) Other specified cardiac dysrhythmias (427.81) Sick sinus syndrome (427.89) Sinus bradycardia, NOS (427.9) Cardiac dysrhythmia unspecified Gallop rhythm (428) Heart failure (428.0) Congestive heart failure unspecified (428.1) Left heart failure Pulmonary edema, acute (428.2) Systolic heart failure (428.3) Diastolic heart failure (428.4) Heart failure, combined, unspec. (wikipedia.org)
  • Susac's syndrome is a very rare disease, of unknown cause, and many persons who experience it do not display the bizarre symptoms named here. (wikipedia.org)
  • William F. Hoyt was the first to call the syndrome "Susac syndrome" and later Robert Daroff asked Dr. Susac to write an editorial in Neurology about the disorder and to use the eponym of Susac syndrome in the title, forever linking this disease with him. (wikipedia.org)
  • Multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM) can mimic the MRI changes seen in patients with Susac's syndrome. (wikipedia.org)
  • Acute hepatomyoencephalopathy (HME) syndrome is the name given to a multi-system disease affecting the liver, muscle and brain which is now known to be caused by phytotoxins. (wikipedia.org)
  • In many districts of western Uttar Pradesh, Uttarakhand, Odisha and Haryana, India, outbreaks of an acute "encephalopathy" syndrome, dubbed as a "mysterious disease", have been an annual feature for many years. (wikipedia.org)
  • At the end of four years, it was concluded that the disease was not encephalitis as so far believed but a fatal multi-system disease affecting liver, muscle and brain called, "acute hepatomyoencephalopathy (HME) syndrome" induced by a phytotoxin. (wikipedia.org)
  • Disappearance of a deadly disease acute hepatomyoencephalopathy syndrome from Saharanpur. (wikipedia.org)
  • necrosis
  • Background: Heparin-induced thrombocytopenia (HIT) can be an antibody-mediated undesirable drug reaction that may result in devastating thromboembolic problems, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and heart stroke. (biomasswars.com)
  • mild
  • Approximately 25% of young camels that become infected will die from the disease, while infection in older camels is generally more mild. (wikipedia.org)
  • attacks
  • Therefore, weak immunity is one of the risk factors of diverticulosis, and it should be regularly boosted by natural food supplements, not only when the disease attacks, but primarily as a form of prevention. (penoxal.com)
  • pathogenic
  • The latest thinking is that an antibody directed against endothelial cells is the pathogenic mechanism in this disease which causes the microscopic strokes in the brain, retina, and inner ear. (wikipedia.org)
  • lethal
  • Pancreatic ductal adenocarcinoma (PDAC) is normally a lethal disease in immediate need to have of newer therapeutic modalities. (biomasswars.com)
  • Rocky Mountain spotted fever (RMSF), also known as blue disease, is the most lethal and most frequently reported rickettsial illness in the United States. (wikipedia.org)
  • treatments
  • It has a positive effect on the bowel movement, which may be utilised in treatments of many diseases that lead to disruption of intestinal wall, and thus increase the risk of developing a more serious disease . (penoxal.com)
  • children
  • Acute mastoiditis is the condition most typically associated with the term "mastoiditis," and this is a complication of acute otitis media seen most often in young children. (neurologyadvisor.com)
  • A recent review of the KIDS inpatient database for the year 2009 showed acute mastoiditis to be the most common complication of acute otitis media in children admitted with a diagnosis of otitis media. (neurologyadvisor.com)
  • This complication was unusual, with 2.4% of children hospitalized with a diagnosis of otitis media also diagnosed with acute otitis media. (neurologyadvisor.com)
  • 102 deaths in two months: What mystery disease is preying on children of Odisha's Malkangiri? (wikipedia.org)
  • Evidence
  • Both patients underwent fluorescein retinal angiography that demonstrated multifocal retinal artery occlusions without evidence of embolic disease. (wikipedia.org)
  • despite
  • This suggests a possible systemic component of this disease, despite the predominance of central nervous system features. (wikipedia.org)
  • seen
  • Introduction: Glaucoma is a multifactorial disease seen as a progressive optic nerve damage and visual field flaws. (biomasswars.com)
  • medical
  • Collected references on the disease and related topics, including general press, medical journals, and public health departments of affected countries. (dmoztools.net)
  • The disease was first identified in the Rocky Mountain region, but beginning in the 1930s, medical researchers realized that it occurred in many other areas of the United States. (wikipedia.org)
  • different
  • The following represents MIC susceptibility data for a few medically significant pathogens: Mycoplasma bovis: 0.06 - 4 μg/ml Staphylococcus aureus: 0.5 - >128 μg/ml Tylosin has been used to treat a variety of different diseases throughout the world. (wikipedia.org)
  • usually
  • The drainage is usually indicative of a tympanic membrane perforation or a cholesteatoma, and the bacteriology differs from that of acute mastoiditis. (neurologyadvisor.com)
  • central
  • It is now recognized that the disease is broadly distributed throughout the contiguous United States and occurs as far north as Canada and as far south as Central America and parts of South America. (wikipedia.org)
  • areas
  • Examination of the mastoid and periauricular areas can differentiate between simple acute otitis media or complicated otitis media with mastoiditis. (neurologyadvisor.com)
  • state
  • Between 1981 and 1996, the disease was reported from every state of the United States except for Hawaii, Vermont, Maine, and Alaska. (wikipedia.org)
  • time
  • For some time diverticulosis has been known as the " presidents' disease" as it coincidentally occurred in two former European presidents at the same time. (penoxal.com)
  • early
  • Spotted fever can be very difficult to diagnose in its early stages, and even experienced doctors who are familiar with the disease find it hard to detect. (wikipedia.org)