Acute cannabis. Medical search. Frequent questions

Another psychoactive cannabinoid present in Cannabis sativa is tetrahydrocannabivarin (THCV), but it is only found in small amounts and is a cannabinoid antagonist. (wikipedia.org)
Cannabidiol (CBD) is a chemical in the Cannabis sativa plant, also known as cannabis or hemp. (medlineplus.gov)
Over 80 chemicals, known as cannabinoids, have been found in the Cannabis sativa plant. (medlineplus.gov)
But CBD is obtained from hemp, a form of the Cannabis sativa plant that only contains small amounts of THC. (medlineplus.gov)
It's made from the flowers, leaves, and resin (sticky chemical) of the Cannabis sativa plant. (mskcc.org)
Cannabis sativa has been used for a wide variety of industrial, medical, and non-medical uses for thousands of years, yet remains a source of controversy across the fields of medicine, law, and occupational safety 1-5 . (cdc.gov)
Cannabis sativa contains 120 cannabinoids, only two of which have been studied for medical use: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) 7-9 . (cdc.gov)
There are two main types of cannabis plants used for marijuana: sativa and indica. (everydayhealth.com)
Hemp plants, which are another type of cannabis plant, do not produce anywhere near the high that sativa and indica plants do. (everydayhealth.com)
Use of marijuana ( Cannabis sativa ) often begins in adolescence, and heavy adolescent marijuana use is often associated with impaired cognitive function in adulthood. (nature.com)
Cannabis sativa is the source of cannabis and its derivatives. (news-medical.net)

Cannabis extracts contain in addition to Δ-9 and Δ 8 -THC many other cannabinoids and chemical compounds, such as esters and alkaloids, the effects of which will have to be evaluated separately and in combination. (unodc.org)
The effects of cannabis are caused by chemical compounds in the cannabis plant, including 113[clarification needed] different cannabinoids such as tetrahydrocannabinol (THC) and 120 terpenes, which allow its drug to have various psychological and physiological effects on the human body. (wikipedia.org)
Different plants of the genus Cannabis contain different and often unpredictable concentrations of THC and other cannabinoids and hundreds of other molecules that have a pharmacological effect, so the final net effect cannot reliably be foreseen. (wikipedia.org)
The most prevalent psychoactive substances in cannabis are cannabinoids, particularly THC. (wikipedia.org)
The increased popularity of cannabis for medical purposes and the narrowing gap in prevalence of use between men and women raises questions regarding sex-dependent effects related to therapeutic efficacy and negative health effects of cannabis and cannabinoids. (nature.com)
The objective of this review is to provide a translational perspective on the sex-dependent effects of cannabis and cannabinoids by synthesizing findings from preclinical and clinical studies focused on sex comparisons of their therapeutic potential and abuse liability, two specific areas that are of significant public health relevance. (nature.com)
Hormonal and pharmacological mechanisms that may underlie sex differences in the effects of cannabis and cannabinoids are highlighted. (nature.com)
Molecules unique to cannabis are known as cannabinoids, each of which exerts varied effects through cannabinoid receptors. (gssiweb.org)
While there are very real issues surrounding suitability, safety, and ethical use of cannabis in sport, the focus of this Sports Science Exchange article is to explore the effects of whole cannabis use, and one of its most abundant cannabinoids, delta-9-tetrahydrocannabinol (THC), on human physiology and exercise performance. (gssiweb.org)
The plant genus Cannabis is a prolific producer of unique pharmaceutically relevant metabolites, commonly referred to as cannabinoids. (researchgate.net)
Robust and standardised methods for the quantification of cannabinoids within botanical and drug forms is a critical step forward for an emerging Cannabis-based pharmaceutical industry, which is poised for rapid expansion. (researchgate.net)
Acute intoxications by synthetic cannabinoids appear to be increasing in the United States. (cdc.gov)
Recent reports suggest that acute intoxications by synthetic cannabinoids are increasing in the United States ( 1 , 2 ). (cdc.gov)
Studies of synthetic cannabinoids indicate higher cannabinoid receptor binding affinities, effects two to 100 times more potent than Δ 9 -tetrahydrocannabinol (the principal psychoactive constituent of cannabis), noncannabinoid receptor binding, and genotoxicity ( 4 , 5 ). (cdc.gov)
Known by several names, such as marijuana for dried flower buds and hashish for plant resin blocks, cannabis contains multiple bioactive compounds like flavonoids, cannabinol, and cannabinoids. (news-medical.net)
Some of the most notable cannabinoids founds within cannabis include the potent psychoactive compound delta-9-tetrahydrocannabinol (THC) and anti-inflammatory cannabidiol (CBD). (news-medical.net)
According to Bloch (1983) who reviewed the literature for the World Health Organisation: 'in vivo and in vitro exposure to purified cannabinoids or cannabis resin failed to increase the frequency of chromosomal damage or mutagenesis' (p412). (druglibrary.org)
More recently, Zimmerman and Zimmerman (1990/1991) concluded that 'cannabis mutagenicity remains unclear', but argued that there was evidence that 'cannabinoids induce chromosome aberrations in both in vivo and in vitro studies' (p19). (druglibrary.org)
Leuchtenberger, 1983), suggesting that if cannabis smoke is carcinogenic it is more likely to be because of the carcinogens it shares with cigarette smoke rather than because of the cannabinoids it contains. (druglibrary.org)

If you don't have open communication between a doctor and patient then cannabis use can be dangerous," said Grinspoon, the author of Seeing Through the Smoke: A Cannabis Specialist Untangles the Truth About Marijuana . (medscape.com)
Only about 15% of US medical schools teach about medical marijuana and the endocannabinoid system, through which cannabis works in the body. (medscape.com)
In the Netherlands, where the distribution of marijuana has been legalized, the effect of decriminalization has had little effect on the consumption rate of cannabis. (medscape.com)
Our case highlights the underdiagnosed association of marijuana use with clinically significant hypokalemia and the rare presentation of severe hypokalemia with acute paralysis. (kansascity.edu)
Cannabis, also known as marijuana, is used to treat some symptoms related to cancer. (mskcc.org)
Since then, medical cannabis has been legalized in 28 states and the District of Columbia for a multitude of indications that vary from state to state ( MPP (Marijuana Policy Project), 2016 ). (nature.com)
These and other changes are typically less pronounced in subjects who are more habitual cannabis consumers, but they may be exacerbated when alcohol and marijuana are ingested in combination with one another. (norml.org)
Recreational Cannabis is legal in almost a dozen states and medical marijuana in 33 states with more on the way. (thomsonreuters.com)
Chances are, if your state hasn't legalized marijuana, the only agencies dealing with cannabis in an appreciable way is law enforcement, Hudak added. (thomsonreuters.com)
Marijuana is a drug that comes from the flowers and leaves of the cannabis plant. (everydayhealth.com)
Cannabis is the botanical name of the plant, and marijuana is the name for the drug derived from the plant. (everydayhealth.com)
Cannabis is grown, whereas marijuana is smoked. (everydayhealth.com)
Marijuana (cannabis) is probably the most common recreational drug combined with alcohol. (drugs.com)
Marijuana produces well-documented, acute cognitive changes that last for several hours after the drug has been ingested. (cmaj.ca)
Most studies that examined heavy marijuana users for possible cognitive dysfunction lasting beyond the acute intoxication period assessed subjects after an abstinence period of only a day or two. (cmaj.ca)
Today, the drug-war era stigma against marijuana use persists, despite its mass commercialization across the U.S. A survey on the now billion-dollar trade, " Diversity, Equity & Inclusion in the Cannabis Industry ," reports that as of 2022, only 23% of executive roles are held by women in the cannabis industry, and only 12% by racial minorities. (latina.com)
Cannabis remains a Schedule I substance federally, therefore patients and caregivers should utilize state programs, such as the PA Medical Marijuana Program, which has regulatory standards in place for production and testing. (nxtbook.com)
Regular use of alcohol, cannabis (marijuana), nicotine , or other drugs during adolescence is associated with higher rates of mental health disorders, poorer functioning in adulthood, and higher rates of addiction. (msdmanuals.com)

Although some assert that cannabidiol (CBD), another cannabinoid found in cannabis in varying amounts, may alleviate the adverse effects of THC that some users experience, little is known about CBD effects on humans. (wikipedia.org)
Cannabinoid receptor antagonists have previously been tested as antidotes for cannabis intoxication with success, reducing or eliminating the physiological and psychological effects of intoxication. (wikipedia.org)
Cannabis is suspected of being a potential contributory factor or direct cause of sudden death, due to the strain it can place on the cardiovascular system, or because of cannabinoid hyperemesis syndrome. (wikipedia.org)
TORONTO, ON / ACCESSWIRE / September 19, 2023 / CanaQuest Medical Corp ("CanaQuest" or the "Company") (OTC:CANQF), a clinical-stage life sciences company focused on drug discovery and development of next-generation targeted cannabinoid therapeutics for the central nervous system (CNS), is pleased to announce it was awarded a European Cannabinoid Patent, a novel Botanical and Tetrahydrocannabinol ("THC") Formulation for the reduction of cannabis-induced negative neuropsychiatric side-effects. (kdvr.com)
Cannabis can be consumed in different ways, with method of consumption and cannabinoid composition modulating the drug's effects. (gssiweb.org)
Validation parameters for establishing robust standardised methods for cannabinoid quantification within Cannabis-based drug forms are critically discussed. (researchgate.net)
The increase in acute synthetic cannabinoid poisonings underscores the importance of targeted prevention interventions and the need for education about the potentially life-threatening consequences of synthetic cannabinoid use. (cdc.gov)
Four hundred and nine people with a specified condition of insomnia completed 1056 medical cannabis administration sessions using the Releaf App TM educational software during which they recorded real-time ratings of self-perceived insomnia severity levels prior to and following consumption, experienced side effects, and product characteristics, including combustion method, cannabis subtypes, and/or major cannabinoid contents of cannabis consumed. (mdpi.com)
If cannabinoid exposure affects the genetic material of a user's somatic or bodily cells (such as those of the lung, for example) then chronic cannabis use may cause cancer. (druglibrary.org)
If it is the non-cannabinoid components of cannabis smoke that are mutagenic, then any cancers caused by cannabis smoking are most likely to develop after long-term exposure to cannabis smoke, and they are most likely to develop at sites which have had the maximum exposure to that smoke, namely, the upper aerodigestive tract and lung. (druglibrary.org)

Cite this: Physicians Aren't Asking Enough Questions About Cannabis Use - Medscape - Aug 29, 2023. (medscape.com)

Some evidence points to benefits of cannabis for PTSD, including a study published in the journal Psychiatry and Neuroscience in March 2019. (medscape.com)
The study analyzed data from the National Poison Data System from 2017 to 2019 and found that the rate of pediatric edible cannabis exposures increased by 34.6% per year during this period. (remedyguard.com)
Cannabis contains over 100 genus-specific molecules, known as phytocannabinoids (Amin & Ali, 2019). (gssiweb.org)
Alan Horowitz was quoted in the March 7, 2019 InFront on Post-Acute HR's article, titled "Addressing the Cannabis Conundrum: Are you ready to handle the issues, challenges of legal medical cannabis? (agg.com)
Therefore, patients and caregivers need to advocate for themselves (or for their patients) 26 Philadelphia Medicine : Fall/Winter 2019 and review quality research, communicate with their physicians, and consult the medical professionals available, by law, at Pennsylvania (PA) medical cannabis dispensaries. (nxtbook.com)

The lack of questioning is concerning for both doctors and patients: while moderate use of cannabis and cannabidiol (CBD) may be safe on their own when combined with certain medications, the substance can cause serious side effects. (medscape.com)
A total 442 healthy young cannabis users were tested while intoxicated with their own cannabis-which was analysed for delta-9-tetrahydrocannbinol (THC) and cannabidiol content-and also ±7 days apart when drug-free. (edu.au)

The acute oral toxicity of the cannabis derivatives used as intoxicants (marihuana, kif, hashish) is low. (unodc.org)
However, the acute toxicity of Δ 9 -THC, especially when administered intravenously is much greater. (unodc.org)
THC, the principal psychoactive constituent of the cannabis plant, has an extremely low toxicity and the amount that can enter the body through the consumption of cannabis plants poses no threat of death. (wikipedia.org)
Acute inflammation of the pericardium may be infectious in origin or may be due to systemic diseases (autoimmune syndromes, uremia), neoplasm, radiation, drug toxicity, hemopericardium, or contiguous inflammatory processes in the myocardium or lung. (health.am)
1 Its use poses a significant public health problem due to its known acute toxicity (hyperthermia and related medical complications). (cambridge.org)

An April 2020 study published in the American Journal of Geriatric Psychiatry found that anxiety was among the most common reasons why older patients use cannabis and that patients found it effective for alleviating symptoms. (medscape.com)
Cannabis is one of the most widely used recreational substances in the world, second only to alcohol (United Nations Office on Drugs and Crime, 2020). (gssiweb.org)
This includes potential applications for athletic performance, but the empirical case for or against cannabis use in sport remains unclear due to regulatory barriers, which have limited its study (Haney, 2020). (gssiweb.org)
By January 2020, severe acute respiratory syndrome coronavirus-2 has spread internationally to a pandemic that mainly targets the respiratory system. (bvsalud.org)

All of this is taking place in the context of limited evidence that cannabis is safe. (news-medical.net)
There is stronger and more consistent evidence that cannabis smoke, like smoke produced by most burning plant material, is mutagenic in vitro, and hence, is potentially carcinogenic (Leuchtenberger, 1983). (druglibrary.org)

Cannabis use has historically been thought to cause amotivation, but the relationship between cannabis and apathy, anhedonia, and reward processing remains poorly characterised. (ucl.ac.uk)
Research is needed to explore the incidence of cannabis consumption by industry and occupation, as well as the relationship between cannabis consumption by workers and occupational injuries. (cdc.gov)
Furthermore, the relationship between cannabis use and postoperative opioid use remains poorly understood in this population. (isakos.com)

Although cannabis may reduce symptoms of depression and anxiety, doctors must look below the surface at what's causing the symptoms. (medscape.com)
Variation at the rs2494732 locus of the AKT1 gene predicted acute psychotic response to cannabis along with dependence on the drug and baseline schizotypal symptoms. (edu.au)
Additionally, individuals who reported using cannabis to try to fit in with friends, displayed cannabis use disorder symptoms or had anxiety sensitivity -- a tendency to imagine the worse possible outcome -- were more likely to report adverse reactions as well as experiencing a greater amount of distress. (sciencedaily.com)
CUD is characterized by dependence, withdrawal symptoms, failure to meet work, school, or home responsibilities, tolerance to greater amounts of cannabis, and other qualifying symptoms 22-25 . (cdc.gov)
Medical cannabis may worsen symptoms in some patients. (nxtbook.com)
Methods: First, using a baseline questionnaire, our study characterized the prevalence of work-related allergic and irritant symptoms and their association with exposure in workers in an indoor cannabis growing facility (n=31). (cdc.gov)
Second, for two weeks, lung function and airway inflammation were measured in a subset of workers with work-related symptoms to characterize acute and chronic changes in these two measures (n=10). (cdc.gov)
Our findings suggested that workers with higher exposure to cannabis may have increased odds of having work related symptoms, although none of the associations were statistically significant. (cdc.gov)
Finally, 50% of participants in our sub-cohort of 10 workers with work-related symptoms were sensitized to cannabis. (cdc.gov)
Conclusion: The high prevalence of work-related symptoms, cannabis sensitization and impaired lung function observed in our study, raises the possibility that occupational exposures to cannabis are harmful to workers in this industry. (cdc.gov)
Quitting Cannabis and Preventing Pulmonary Illness Patients who smoke cannabis might not realize that this habit can result in respiratory symptoms. (medscape.com)

THC produces psychoactive effects in consumers and is responsible for the "high" associated with cannabis 10,11 . (cdc.gov)
Here, we investigated the effect of acute and repeated treatment with ∆(9)-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, on PPI in rats, and the role of dopamine D₂/₃-receptor blockade in this effect. (unige.ch)
Higher Dining has become a hub for cannabis users and newcomers alike, looking to flavorfully experiment with the psychoactive. (latina.com)

In a large health insurance claims database, persons who used cannabis were 3.5 (95% CI 2.6-4.8) times more likely than persons who did not use cannabis to have a fungal infection in 2016. (cdc.gov)
We used health insurance claims data from 2016 to evaluate the prevalence of fungal infection diagnosis codes among persons who use cannabis and persons who do not use cannabis and to compare demographic and clinical features between these 2 groups. (cdc.gov)
As of 2016, 8 states and the District of Columbia have also legalized cannabis for recreational use ( NCSL (National Conference of State Legislatures), 2017 ). (nature.com)
for example, past-month cannabis use increased from 6.2% to 8.3% between 2002 and 2015 ( Center for Behavioral Health Statistics and Quality, 2016 ). (nature.com)
Ribeiro & Ind, 2016), which fuels speculation that cannabis could also affect exercise capacity. (gssiweb.org)

With the legalization of cannabis in Washington and 10 other states, we thought it would be important to document some of this information so that more novice users would have a better sense of what types of adverse reactions they may experience if they use cannabis. (sciencedaily.com)
Few reports are available about sensitization to cannabis in particular, but by evolving the legalization of cannabis, it is likely that this problem will increase in the future. (cdc.gov)

There's been surprisingly little research on the prevalence or frequency of various adverse reactions to cannabis and almost no research trying to predict who is more likely to experience these types of adverse reactions," said Carrie Cuttler, assistant professor of psychology and an author on the paper. (sciencedaily.com)
Even though there has been considerable research about cannabis consumption, driver performance, and vehicular crashes indicating that driving under the influence of cannabis does increase the risk of traffic crashes 24,26,28,35-38 , further research is needed to determine the prevalence of cannabis consumption by workers who drive as part of their job. (cdc.gov)
2005). The high prevalence of cannabis use, in both athletes and the general population, warrants education on use for individuals, coaches, and (sport) scientists. (gssiweb.org)
Third, in the same subset of workers, a skin prick test was used to characterize the prevalence of cannabis sensitization. (cdc.gov)
OBJECTIVES: The purpose of this study was to estimate the prevalence, risk factors, and outcomes associated with acute cardiac events during COVID-19-associated hospitalizations among adults. (cdc.gov)

The researchers are collaborating with medical cannabis company EMMAC Life Sciences and The Institute of Cancer Research , London, to better understand the effectiveness of the products. (imperial.ac.uk)

1 , 2 , 3 Whether it produces cognitive dysfunction beyond this period of acute intoxication is much more difficult to establish. (cmaj.ca)
Grandma's brownies are not what they used to be: Acute intoxication from cannabis ingestion. (bvsalud.org)

The frequency of fungal infections associated with cannabis is unknown but is a growing concern as more states legalize its medicinal and recreational use. (cdc.gov)
Recent policy changes have led to significant increases in the use of cannabis for both medical and recreational purposes. (nature.com)
Over the last two decades, the policy landscape of cannabis legalization for medical and recreational use has undergone significant changes in the U.S. California was the first state to legalize the use of cannabis for medical purposes in 1996. (nature.com)
Given the widespread use of cannabis for both medical and recreational purposes, and the emerging trend of more women using cannabis and cannabis-derived products, identifying potential sex differences in the therapeutic effects and risks associated with cannabis use is a public health imperative. (nature.com)
This review synthesizes findings from preclinical (animal) and clinical (human) sex difference studies guided by epidemiological findings that underscore two significant public health issues arising from changing legislation regarding cannabis for medical and recreational use: therapeutic potential and abuse liability. (nature.com)
Despite remaining on the prohibited substance list of the World Anti-Doping Agency, the use of cannabis is widely reported among athletic populations for both recreational and performance-related purposes. (gssiweb.org)
With an increasing number of governments legalizing recreational use, mainstream acceptance of cannabis is evolving, and the scientific study of cannabis administration to affect psychological and physiological functioning is expanding to include applications in medicine and beyond. (gssiweb.org)
2003). This includes both recreational cannabis use, as well as consumption with the intention of gaining a competitive advantage. (gssiweb.org)
2003). Notably, there is also a relation between using cannabis as a recreational drug and the chances of seeking to use it to enhance some aspect of sport performance (Lorente et al. (gssiweb.org)
With the legalization of recreational cannabis use just months away, the federal government is 'stepping a little into the dark,' according to the scientist who helped create pot use guidelines for Canada. (cbc.ca)
While cannabis is being increasingly used as a recreational drug, in addition to its medical use for the treatment of chronic pain, there is little evidence of its safety. (news-medical.net)
Adverse Effects of Recreational and Medical Cannabis. (news-medical.net)
Background: Legalization of recreational cannabis in multiple states, including Washington, has scaled up cultivation of this plant. (cdc.gov)

Acute psychological and physiological effects of MDMA ('Ecstasy') afte. (erowid.org)

By contrast, the ingestion of CBD-dominant cannabis strains has not been associated with similar changes in driving performance. (norml.org)
As does Roshelly and Shanelly's acute understanding of varying cannabis strains. (latina.com)

Kosten noted that older military veterans may turn to cannabis to help ease post-traumatic stress disorder (PTSD). (medscape.com)
Cannabis use disorder is defined as a medical diagnosis in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). (wikipedia.org)
Smoking cannabis daily doubles an individual's risk of developing a psychotic disorder, yet indicators of specific vulnerability have proved largely elusive. (edu.au)
Although men are more likely to endorse past month cannabis use and are more frequently diagnosed with Cannabis Use Disorder relative to women, a growing proportion of medical cannabis users are reported to be women. (nature.com)

People who are regular cannabis users are at an increased risk of experiencing complications before, during, and after surgery, according to a study by researchers with UTHealth Houston published today in JAMA Surgery. (medicalxpress.com)
Researchers concluded: "In a placebo-controlled parallel study of regular cannabis users smoking cannabis with different THC content ad libitum , there was statistically significant worsening on driving simulator performance in the THC group compared with the placebo group. (norml.org)

Questionnaire studies demonstrated greater anhedonia in adolescent cannabis users, and some indication of greater apathy in young adult cannabis users. (ucl.ac.uk)
Behavioural studies yielded some evidence of reduced reward learning in adolescent cannabis users, though there were too few studies in this category for reliable conclusions. (ucl.ac.uk)

The study notes that healthcare providers should be aware of the unique clinical effects of edible cannabis and consider it as a potential cause of acute poisoning in children. (remedyguard.com)
Viral infections (especially infections with coxsackieviruses and echoviruses but also influenza, Epstein-Barr, varicella, hepatitis, mumps, and HIV viruses) are the commonest cause of acute pericarditis and probably are responsible for many cases classified as idiopathic. (health.am)

Many patients turn to cannabis because the side effects are more tolerable than other medications, Grinspoon said. (medscape.com)
The study also found that pediatric edible cannabis exposures were more likely to result in moderate to severe clinical effects, including respiratory depression, lethargy, and seizures, compared to non-edible cannabis exposures. (remedyguard.com)
Consequently, the reports of toxicologic and pharmacologic effects of crude extracts or synthetic derivatives of cannabis published before 1968 lack precision and uniformity and preclude any quantitative correlation between physiological effects and chemical composition. (unodc.org)
However, one cannot draw a complete parallel between the pharmacological or other effects produced by Δ 9 -THC and those engendered by cannabis extracts. (unodc.org)
Acute effects while under the influence can sometimes include euphoria or anxiety. (wikipedia.org)
Like most other neurological processes, the effects of cannabis on the brain follow the standard protocol of signal transduction, the electrochemical system of sending signals through neurons for a biological response. (wikipedia.org)
When cannabis is smoked, blood levels of THC peak rapidly after a few minutes and then decline, although the psychotropic effects persist for longer. (wikipedia.org)
These acute effects occur via the endocannabinoid type 1 (CB1) receptor. (drugs.com)
There is currently limited applicable evidence regarding the physiological effects of cannabis during exercise or the impact on performance. (gssiweb.org)
Understanding the short- and long-term effects of cannabis on human performance requires targeted and well-controlled athlete-specific investigations with applied performance outcomes. (gssiweb.org)
Furthermore, the known psychological effects of cannabis use, including its influence on arousal, anxiety, recovery, decision making, and motor control could have implications for sport performance (Close et al. (gssiweb.org)
Self-administered WIN did not produce either acute or chronic effects on short-term memory, but experimenter administration of WIN in adolescence, at doses previously reported in the literature, produced acute deficits in short-term memory that recovered with abstinence. (nature.com)
Dr. Benedikt Fischer, a senior scientist at the Centre for Addiction and Mental Health in Toronto, said cannabis is a complex drug - and there's still a lot we don't know about its effects. (cbc.ca)
acute exposure is associated with a range of mild to severe neuropsychiatric, cardiovascular, renal, and other effects. (cdc.gov)
However, the global impression of any change in pain management was very low among patients, with adverse effects of cannabis use accounting for multiple withdrawals from studies on medical cannabis. (news-medical.net)
6. What are the side effects of medical cannabis? (nxtbook.com)
The long-term effects of medical cannabis are unknown and there is a paucity of high quality clinical trials proving its therapeutic value. (nxtbook.com)
6. The chronic effects of cannabis use on health Cellular and immunological effects The possible effects of chronic cannabis use on cellular processes and the immune system are considered together because both effects may influence a cannabis user's susceptibility to diseases. (druglibrary.org)
6.2 Immunological effects The possibility that cannabis reduces immune system function is important for several reasons. (druglibrary.org)
Health effects of exposure to cannabis in workers in an indoor growing facility. (cdc.gov)

Determining driver impairment from cannabis consumption also remains a complicated but critical research need. (cdc.gov)
Since cannabis is stored in body fat and released into the bloodstream over days or weeks from the time of actual consumption, THC levels detected in a positive urine or blood drug test do not permit sound inferences about the frequency of cannabis consumption, specific time of last use, or cannabis-related impairment 39-42 . (cdc.gov)
Impairment testing provides a promising adjunct or alternative to traditional workplace drug testing that would evaluate real-time deficits in job performance from multiple causes, such as lack of sleep, chronic medical conditions, effect from physician-prescribed medications, and self-prescribed drugs, including cannabis. (cdc.gov)
Future research should address factors such as individual biologic differences, personal experience with cannabis, and cannabis administration methods in relation to driving impairment. (norml.org)

In states like California, the stark increase has resulted in a 1808% jump in the rate of cannabis-related visits by seniors to the emergency room, according to a study published this past January in the Journal of the American Geriatric Society . (medscape.com)
Now that many American states have legalized cannabis, the already high rate of cannabis usage is increasing from ages as young as 16 years. (news-medical.net)

Future large-scale, longitudinal studies which use multiple behavioural and neuroimaging measures of reward processing may further clarify the impact of cannabis use on motivational and reward processes, and neural networks. (ucl.ac.uk)
The federal government put aside $20 million in its most recent budget for research into the impact of cannabis use in Canada. (cbc.ca)

Oxygenation in ARDS: A Comparison of Safety, Efficacy Three modes of oxygen delivery are compared in patients with acute hypoxemic respiratory failure. (medscape.com)

The toolbox of treatment options or evidence-based forms of treatment for cannabis is extremely limited. (cbc.ca)

Access to and consumption of cannabis have increased as a result of more favorable public attitudes and state access laws. (cdc.gov)
Increasing access to and consumption of cannabis by workers have led to increased concerns about workplace safety 4,26-29 . (cdc.gov)

As the use of cannabis becomes increasingly legalized and normalized in the United States, there is growing concern over the potential for unintentional exposure and acute poisoning, particularly in children. (remedyguard.com)
In this systematic review, we evaluated whether cannabis exposure acutely and/or non-acutely was associated with altered reward processing using questionnaire, behavioural, or functional neuroimaging measures. (ucl.ac.uk)
Preventive measures are recommended to reduce worker exposure to cannabis, especially in areas with high concentration of dust. (cdc.gov)

As medicinal cannabis has not gone through the normal drug development pathway that the pharma industry and medical profession are used to, we have a lot of work to do to provide robust data to support clinical effectiveness as well as determine efficacy of different constituents of the plant. (imperial.ac.uk)
Mr Sodergren, who is also a paid scientific advisor to EMMAC Life Sciences, hopes to place our understanding of the clinical effectiveness of cannabis on a more evidenced-based footing. (imperial.ac.uk)
Patients hospitalized with acute heart failure were 36% more likely to experience a clinical benefit over 90 days if started on Jardiance following stabilization and prior to discharge compared to placebo. (seekingalpha.com)
Full text of the study, "Driving performance and cannabis users' perception of safety: A randomized clinical trial," appears in JAMA Psychiatry. (norml.org)

The researchers will also examine whether CBD, one of the main active compounds in cannabis, could help treat cancer. (imperial.ac.uk)
Limited research on occupational health hazards of working with cannabis has shown potential occupational exposures to volatile organic compounds, plant proteins, and microbial contaminants. (cdc.gov)

Western University researchers believe this formulation may mitigate this type of harm to chronic cannabis users. (kdvr.com)

Cannabis was widely used for a variety of medical ailments throughout the 19th and early 20th centuries, until a series of federal laws beginning in the 1930s penalized the sale and use of medicinal cannabis and ended its legitimate medical use 16 . (cdc.gov)

Additionally, cannabis use is not a risk for postoperative complications, and cannabis users have a lower risk of CVA, PE, and DVT. (isakos.com)
Despite the increasing frequency of use among patients, there is a paucity of data on the influence of cannabis on shoulder arthroscopy, particularly with regard to complications. (isakos.com)

Edible cannabis products, in particular, have become a popular form of consumption, and their often colorful packaging and sweet flavors can make them appealing to children. (remedyguard.com)
A recent study published in the journal Pediatrics highlights the alarming increase in pediatric edible cannabis exposures and acute poisoning. (remedyguard.com)
The findings of this study underscore the need for greater public education and regulation around edible cannabis products. (remedyguard.com)
In addition to public education and regulation, healthcare providers also play a crucial role in identifying and managing pediatric edible cannabis exposures. (remedyguard.com)
Prompt and appropriate management of pediatric edible cannabis exposures can prevent serious harm and even death. (remedyguard.com)
In conclusion, the increasing rate of pediatric edible cannabis exposures and acute poisoning is a cause for concern and underscores the need for greater public education, regulation, and healthcare provider awareness. (remedyguard.com)
Edible forms of cannabis often contain several hundred milligrams of THC, much more than the 32 mg of a typical cannabis cigarette. (wikipedia.org)
The rise of edible cannabis products has been responsible for a large increase of poisoning of children and young people: in American states which have legalized cannabis, emergency room admissions of such cases have typically doubled. (wikipedia.org)
In the second part of CBC Toronto's Joint Ventures series, we take a look at the edible side of the flourishing cannabis industry in the lead up to legalization. (cbc.ca)

The researchers surveyed more than 1,500 college students on the type and frequency of adverse reactions they had experienced while using cannabis for their study in the Journal of Cannabis Research . (sciencedaily.com)
Though the frequency of serious adverse events was not found to be increased with medical cannabis as compared to placebo, the former appeared to impact the nervous system, with a higher risk of psychiatric disorders. (news-medical.net)
Dr. Flaherty researches epilepsy and highlighted stress reduction as a tool to decrease the frequency and severity of seizures which medical cannabis may offer with benefits like improved sleep or lowered anxiety," explained Gockley. (nxtbook.com)
Patients may use medical cannabis for a variety of reasons, but the most common goals of those with epileptic conditions are to decrease the frequency and severity of seizures, reduce the need for traditional anti-epileptic medications, shorten recovery time and improve mood and sleep. (nxtbook.com)
The acute and long-term consequences range from minimal to minor to life threatening, depending on the substance, the circumstances, and the frequency of use. (msdmanuals.com)

In 2017, they came up with the plan to host their first cannabis dinner party in their mom's backyard in Northern New Jersey. (latina.com)

Working memory following cannabis acutely was worse in females, with some suggestion of an impact of COMT polymorphism on working memory when drug-free. (edu.au)

Typical cannabis products, prepared from the flowering tops of the unfertilized female plant, contain 7 to 14 percent THC 7 . (cdc.gov)
The amount of THC and CBD in each cannabis plant is variable and depends on how it was grown, prepared, and stored. (everydayhealth.com)
Everything about the [cannabis] plant plays a role, from the THC levels to the terpenes (aromatic oils that give weed its distinctive smell). (latina.com)

We used Treatment Pathways, a web-based platform ( https://www.ibm.com/us-en/marketplace/marketscan-treatment-pathways ), which enable users to query data for persons whose health insurance plans or employers contribute prescription drug data to MarketScan. (cdc.gov)
citation needed] Long-term users can produce positive tests for two to three months after ceasing cannabis use (see drug test). (wikipedia.org)
This suggests cannabis users do not, in general, find acute adverse reactions to cannabis to be severely distressing. (sciencedaily.com)
Furthermore, cannabis users experienced significantly fewer DVT at 30 days (OR 0.5815, p=0.023) and 90 days (OR 0.6600, p=0.024) and PE at 30 days (OR 0.3990, p=0.014) and 90 days (OR 0.3426, p=0.002). (isakos.com)
If cannabis use affects cellular processes then users may be at increased risk of developing various types of cancer, and if it affects the immune system then cannabis users may be at increased risk of contracting infectious diseases and developing cancer. (druglibrary.org)
If it affects the genetic material of germ cells (the sperm and ova), then genetic mutations could be transmitted to the children of cannabis users. (druglibrary.org)

As more older adults turn to cannabis to alleviate medical ailments like pain, insomnia , and anxiety, many physicians are hesitant to ask their patients about the topic or advise them about possible health impacts. (medscape.com)
Seniors may also turn to cannabis to help with their depression and anxiety, said Thomas Kosten, MD, a professor of psychiatry at Baylor College of Medicine in Houston. (medscape.com)
Cannabis was marketed as extract or tincture by several pharmaceutical companies and used for ailments such as anxiety and lack of appetite. (medscape.com)
Coughing fits, anxiety and paranoia are three of the most common adverse reactions to cannabis, according to a recent study. (sciencedaily.com)
More than 50% of the study participants reported having experienced coughing fits, anxiety and/or paranoia while using cannabis. (sciencedaily.com)

If effective, medical cannabis could provide an alternative to opioid painkillers, which are at the centre of an addiction crisis in the US and prompting fears of a similar epidemic in the UK. (imperial.ac.uk)
Addiction often begins when patients are prescribed a course of opioid painkillers for acute pain, and there is therefore great interest in effective and less addictive alternatives. (imperial.ac.uk)
One aspect of the Imperial research will be to trial medical cannabis in patients who have had major abdominal surgery, while tracking their opioid use to see if this decreases. (imperial.ac.uk)
We hypothesized that complication rates, postoperative opioid use, and cost does not differ between patients with and without cannabis use. (isakos.com)

Acute alcohol use, depending on its concentration, can reduce GBH break down in the body and increase GHB levels in the blood. (drugs.com)
The substances that are used most by adolescents are alcohol, nicotine (in tobacco or vaping products), and cannabis. (msdmanuals.com)

Cannabis use, particularly in adolescence, is frequently associated with negative long-term functional outcomes. (nature.com)
acute and long term health consequences are? (cbc.ca)
These products put adolescents who do initiate substance use at higher risk of developing both acute and long-term consequences. (msdmanuals.com)

Delta-9-tetrahydrocannabinol (THC) is the most famous ingredient in cannabis. (medlineplus.gov)
Delta-9-tetrahydrocannabinol (THC) is the primary component of cannabis that leads to the "high" experience. (drugs.com)

Medical cannabis is widely prescribed in countries such as Germany and the USA and was legalised in the UK in October 2018. (imperial.ac.uk)
The researchers aim to provide robust data that will help bodies like NICE, which has backed a government call for further industry research into medical cannabis, to determine whether or not cannabis-based medicinal products are safe and effective enough to recommend for given conditions. (imperial.ac.uk)
Although there is already undoubted evidence that medical cannabis works for certain conditions, for example childhood epilepsy, there are also all sorts of claims that are not yet substantiated. (imperial.ac.uk)
Many physicians are hesitant to advise their patients on cannabis use because they weren't taught about it in medical school, Grinspoon said. (medscape.com)
In the United States, medical cannabis research is limited by federal restrictions. (wikipedia.org)
Moving forward, Cuttler hopes the results of the study will be put to use by doctors, medical cannabis distributors and even bud tenders to give people a better idea of what could go wrong when they get high. (sciencedaily.com)
This increase in medical cannabis use by women raises the question of whether its therapeutic efficacy differs as a function of sex. (nature.com)
Medical cannabis sold in dispensaries has a similar THC concentration to cannabis sold for non-medical use 15 . (cdc.gov)
Cannabis is also consumed for enjoyment and without medical justification, using a variety of products with varying potency levels and routes of administration. (cdc.gov)
Exposures may also affect law enforcement, fire fighters, emergency medical technicians, and hazardous materials response personnel working around cannabis or responding to cannabis industry sites 32-34 . (cdc.gov)
Addressing the Cannabis Conundrum: Are You Ready to Handle the Issues, Challenges of Legal Medical Cannabis? (agg.com)
We use a mobile software application (app) to measure for the first time, which fundamental characteristics of raw, natural medical Cannabis flower are associated with changes in perceived insomnia under naturalistic conditions. (mdpi.com)
Moreover, medical cannabis is becoming more common, with 40% of cancer patients using cannabis for pain management when available legally, as in Canada, Germany, and Israel. (news-medical.net)
Medical cannabis is also being used instead of standard therapy for conditions like refractory epilepsy, schizophrenia, or multiple sclerosis. (news-medical.net)
The use of medical cannabis could increase the proportion of people who were able to reduce their pain to half the existing level or less. (news-medical.net)
p h i l a m e d s o c .org FEATURE CURE and EPILEPSY By: Sabrina Andrews, Director of Operations, Cure Pennsylvania I n May the Epilepsy Foundation of Eastern Pennsylvania hosted its annual Lancaster Epilepsy Education Exchange, which included information about medical cannabis. (nxtbook.com)
Dr. Heather D. Harle (MD, Neurologist at Penn Medicine at Lancaster General Health Physicians) presented on the history of cannabis in medicine, the lack of access to quality research at this time, and how important patient-physician communication is when considering, or continuing, to use medical cannabis. (nxtbook.com)
Since the conference, Gockley and some of his fellow pharmacists at Cure provided information that prospective and new medical cannabis patients with epileptic conditions may find helpful. (nxtbook.com)
Common questions patients and caregivers ask about using medical cannabis for treating epileptic conditions include: 1. (nxtbook.com)
5. Can medical cannabis interact with prescription medications? (nxtbook.com)
7. How much do medical cannabis products cost? (nxtbook.com)
an often overlooked risk of using medical cannabis to treat seizures is lack of consistent access or supply. (nxtbook.com)
If hospitalized, a patient may not have access to medical cannabis. (nxtbook.com)
If there are such potential risks and perhaps no benefit in certain patients, why would anyone try medical cannabis for epileptic conditions? (nxtbook.com)
Despite the lack of evidence-based science, success stories shared by medical cannabis patients at Cure and in literature have included reports of reduced number of monthly seizure activity. (nxtbook.com)
To establish the utility of medical cannabis for prevention or treatment of seizures in any patient population, especially children, more data and research is needed. (nxtbook.com)
Only registered patients and caretakers with a certified physician's recommendation may purchase medical cannabis in the state of PA. (nxtbook.com)

Imperial College London researchers are trialling cannabis-based medicinal products for the treatment of cancer and acute pain. (imperial.ac.uk)
This includes storing cannabis products safely out of reach of children, using child-resistant packaging, and labeling products with clear warning labels. (remedyguard.com)
By working together, we can prevent unintentional exposures and ensure the safe and responsible use of cannabis products in our communities. (remedyguard.com)
Some of these products are currently in development as cannabis antidotes. (wikipedia.org)
However, pharmaceutical-grade cannabis products have recently been approved by the U.S. Food and Drug Administration for the treatment of childhood epilepsy syndromes, as well as nausea and vomiting associated with a variety of conditions 17-20 . (cdc.gov)

They also collected information on the students' demographics, personality traits, cannabis use patterns and motives for using the drug. (sciencedaily.com)
and Prof. Rober Mikos of Vanderbilt University, one of the nation's leading experts on federalism and drug law - addressed these legal concerns on a recent webinar, Cannabis Law and Policy , conducted by the Attorney General Alliance and Thomson Reuters. (thomsonreuters.com)
We argue that while some of these challenges remain unique to Cannabis, others are common to botanical-based drug development and manufacture. (researchgate.net)
The compound 3,4-methylenedioxymethamphetamine (MDMA), popularly known as 'ecstasy', is the most commonly misused controlled drug after cannabis among young people in Europe. (cambridge.org)
According to the United Nations Office on Drugs and Crime, cannabis is the most frequently used illicit drug in the world. (news-medical.net)
Second, even a modest reduction in immunity caused by cannabis use could have public health significance because of the relatively large number of young adults who have used the drug (Munson and Fehr, 1983). (druglibrary.org)

The hope is that these systems will improve survival after the most severe form of acute heart failure, cardiogenic shock. (medicalxpress.com)

We further explored differences between ICD-10-CM codes for cannabis abuse or dependence (F12.1 and F12.2) and unspecified cannabis use (i.e., without mention of abuse or dependence) (F12.9). (cdc.gov)

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