• abdominal pain
  • The first case of human infection by a member of the family Anisakidae was reported in the Netherlands by Van Thiel, who described the presence of a marine nematode in a patient suffering from acute abdominal pain. (wikipedia.org)
  • allergen
  • The most common identifiable triggers of anaphylaxis would be food, insect venom or medication while less commonly by allergen such as natural rubber latex or physical factor such as exercise (Simons, 2006). (studymode.com)
  • Thus, IgE is seen as having a crucial role in anaphylaxis where it would be synthesized in response to an allergen exposure and becoming fixed to FcεRI on the surface of mast cells and basophils. (studymode.com)
  • Anaphylaxis is first initiated by the uptake of allergen by professional antigen presenting cells (APCs) which will present selected peptides on MHC class II molecule to naive T cells. (studymode.com)
  • clinical
  • Owing to the nature of anaphylaxis there are few controlled clinical trials, and therapeutic recommendations are based on clinical observation and animal models. (bmj.com)
  • include
  • The 2015 Guidelines Update does not include a separate Part on adult stroke because the content would replicate that already offered in the most recent AHA/American Stroke Association guidelines for the management of acute stroke. (ahajournals.org)
  • common
  • In many individual, anaphylaxis is mediated by the expansion of T helper 2 cell (TH2-cell), a subset of T cells, together with isotype switching of B cells to generate IgE antibodies specific for common environment allergens (Holgate and Polosa, 2008). (studymode.com)
  • hospital
  • 4 5 Most data for the incidence have been derived from hospital databases, and it is widely believed anaphylaxis is under-recognised and under-reported. (bmj.com)
  • oral
  • Preclinical data showed Deflazacort had acute toxicity with an oral lethal dose (LD50) greater than 5,200mg/kg in a mouse. (wikipedia.org)
  • population
  • Epidemiological studies have shown differing results owing to differences in both definitions of anaphylaxis and the population groups studied. (bmj.com)
  • factors
  • Physical factors such as exercise (known as exercise-induced anaphylaxis) or temperature (either hot or cold) may also act as triggers through their direct effects on mast cells. (wikipedia.org)