Acute dextrans. Medical search. Frequent questions

and in certain intravenous fluids to solubilize other factors, such as iron (in a solution known as Iron Dextran). (wikipedia.org)
Patients and methods: A single 1000 mg intravenous (IV) [Am J Med Sci 31 (1999) 213] infusion of iron dextran was evaluated in an open-label study. (johnshopkins.edu)
Parenteral injection of iron dextran may result in high serum iron levels (eg, 500-1000 µg/dL) for several weeks. (medscape.com)
Iron dextran elevates serum iron levels several weeks. (medscape.com)

Dental plaque is rich in dextrans. (wikipedia.org)

Still, no difference has been detected in antithrombotic effectiveness in comparison of intra-arterial and intravenous administration of dextran. (wikipedia.org)
Close to 70% of dextran-40 is excreted in urine within the first 24 hours after intravenous infusion, while the remaining 30% are retained for several more days. (wikipedia.org)
Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition. (wikipedia.org)
Still, no difference has been detected in antithrombotic effectiveness in comparison of intraaterial and intravenous administration of dextran. (the-medical-dictionary.com)
Dextran in intravenous solution provides an osmotically neutral fluid that once in the body is digested by cells into glucose and free water. (the-medical-dictionary.com)
Hypertonic resuscitation - a concentrated intravenous (IV) dose of saline and dextran, a sugar solution - has the potential to help survivors of blunt trauma by improving blood flow and delivery of oxygen to the injured brain while decreasing high pressure in the brain, a common problem for patients with brain injury. (atlantainjurylawblog.com)

Our data demonstrate that C. tropicalis may play a pro-inflammatory role in intestinal injury by exacerbating gut inflammation during the recovery phase of dextran sodium sulfate-induced colitis," the authors wrote. (case.edu)
Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis. (ouhsc.edu)

Dextran: Side effect profile includes anaphylactic reactions, increased bleeding time, rare cases of noncardiogenic pulmonary edema and acute renal failure. (openanesthesia.org)

Outside of these features, larger dextrans, which do not pass out of the vessels, are potent osmotic agents, thus have been used urgently to treat hypovolemia[citation needed]. (wikipedia.org)
The larger dextrans (>60,000 Da) are excreted poorly from the kidney, so remain in the blood for as long as weeks until they are metabolized. (wikipedia.org)
The larger dextrans are excreted poorly from the kidney and therefore remain in the blood for as long as weeks until they are metabolized. (the-medical-dictionary.com)

For patients with acute brain injury, 0.9% saline is preferred. (merckmanuals.com)
The experimental hypertonic saline/dextran (HSD) solution is more concentrated than the current treatment and may offer potential benefits to victims of blunt trauma, Bulger says, including more rapid improvement of blood pressure, improved blood flow to the injured brain while decreasing the high pressure in the brain, and an altered immune system response which may decrease the risk of infection and acute respiratory distress syndrome. (atlantainjurylawblog.com)

In the present study we examined the protective potential of exogenously administered human umbilical cord derived mesenchymal stem cells (UCMSCs) against Dextran Sulfate Sodium (DSS) induced acute colitis in immunodeficient NOD.CB 17 - Prkdc scid /J mice with particular attention to endoplasmic reticulum (ER) stress. (biomedcentral.com)

Dextran is now produced from sucrose by certain lactic acid bacteria of the family lactobacillus. (wikipedia.org)

citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in the osmotic stress technique for applying osmotic pressure to biological molecules. (wikipedia.org)

Rhythmic changes in blood flow direction have been described in the mucosal plexus of mice with acute colitis. (nih.gov)
In this report, we studied mice with acute colitis induced either by dextran sodium sulfate or by trinitrobenzenesulfonic acid. (nih.gov)
Researchers induced colitis symptoms in mice by adding low levels of dextran sodium sulfate to mice drinking water. (case.edu)
The researchers also induced colitis in mice acutely using dextran sodium sulfate, while colitis is often a chronic condition in humans. (case.edu)
Wild-type and St2 −/− mice were used in wound healing experiments and in two experimental models of IBD triggered by 2,4,6-trinitrobenzene sulphonic acid or dextran sodium sulphate (DSS). (bmj.com)
Pentamidine treatment significantly ameliorated the severity of acute colitis in mice, as showed by macroscopic evaluation and histological/biochemical assays in colonic tissues and in plasma. (biomedcentral.com)
Pentamidine exerts a marked anti-inflammatory effect in a mice model of acute colitis, likely targeting S100B activity. (biomedcentral.com)
Methods: BALB/c mice with azoxymethane/dextran sodium sulfate (AOM/DSS)-induced colitis-associated colorectal cancer (CAC), we intraperitoneally treated with commercial preparation of human plasma AAT (4 mg per mouse). (lu.se)

fluorescent-labelled dextran can be used to visualize these endosomes under a microscope. (wikipedia.org)
Dextran coupled with a fluorescent molecule such as fluorescein isothiocyanate can be used to create concentration gradients of diffusible molecules for imaging and allow subsequent characterization of gradient slope. (wikipedia.org)
Fluorescent dextran as a blood plasma marker was given intravenously in guinea pigs under narcosis. (uni-muenchen.de)
The T-ALL cell expresses DsRed fluorescent protein (red) and also visible are bone marrow vasculature (cy5 dextran, blue) and GFP-expressing osteoblastic cells (green). (imperial.ac.uk)
mesenteric arteries (MA) and veins (MV) were mounted on glass cannulas, intravascularly filled with fluorescent dextran and incrementally pressurized above their in vivo physiological values. (bvsalud.org)

We aimed to investigate the effect of pentamidine on intestinal inflammation using an animal model of dextran sodium sulphate (DSS)-induced acute colitis. (biomedcentral.com)

The antithrombotic effect of dextran is mediated through its binding of erythrocytes, platelets, and vascular endothelium, increasing their electronegativity and thus reducing erythrocyte aggregation and platelet adhesiveness. (wikipedia.org)
Solutions of fluorescently-labelled dextran can be perfused through engineered vessels to analyze vascular permeability Dextran is used to make microcarriers for industrial cell culture Orally-administered dextran sodium sulphate is used to induce colitis in animal models of inflammatory bowel disease. (wikipedia.org)
Acute vascular effects of nanoparticle infusion in isolated perfused skin. (cdc.gov)
These observations suggest certain nanoparticle infusions may be associated with acute vascular physiologic effects that merit further attention. (cdc.gov)
FROM THE CLINICAL EDITOR: In this study utilizing a perfused porcine skin flap, specific nanoparticle infusions were demonstrated to be associated with significant acute vascular physiological effects. (cdc.gov)
Vascular permeability to dextran was determined at 100, 200 and 300 % of physiological pressures. (bvsalud.org)

Dextran is a complicating contaminant in the refining of sugar because it elevates the viscosity of sucrose solutions and fouls plumbing. (wikipedia.org)
Dextran is synthesized from sucrose by Leuconostoc mesenteroides streptococcus, and are also produced by bacteria and yeast. (the-medical-dictionary.com)

Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. (wikipedia.org)
Dextran is a branched polysaccharide made of many glucose molecules joined into chains of varying lengths. (the-medical-dictionary.com)

Myeloid cell populations isolated from colonic inflammatory bowel disease (IBD) or murine dextran sulphate sodium (DSS) induced colitis were assessed using flow cytometry and compared to healthy controls. (frontiersin.org)

Acute colitis induced by dextran sodium sulphate (DSS) and spontaneous Gαi2−/− chronic colitis were used to assess the efficacy of ex vivo anti-inflammatory treatment. (gu.se)
Acute haemorrhage and chronic anemia were excluded from the scope of these recommendations. (bvsalud.org)

Colloid solutions (eg, hydroxyethyl starch , albumin , dextrans) are also effective for volume replacement during major hemorrhage. (merckmanuals.com)

This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages. (wikipedia.org)

An uncommon but significant complication of dextran osmotic effect is acute renal failure. (the-medical-dictionary.com)

Dextrans also reduce factor VIII-Ag Von Willebrand factor, thereby decreasing platelet function. (wikipedia.org)

There is evidence that posttraumatic ischemia is important in the pathogenesis of acute spinal cord injury (SCI). (thejns.org)

Acute coronary syndrome (ACS) describes any condition characterized by myocardial ischaemia and reduction in blood flow. (hindawi.com)
Acute coronary syndrome (ACS) is a cardiovascular disease, which describes any condition characterized by signs and symptoms of sudden myocardial ischaemia and reduction in blood flow to the heart [ 1 ]. (hindawi.com)

Dextran chains are of varying lengths (from 3 to 2000 kilodaltons). (wikipedia.org)

The chemical causes acute intestinal injury, similar to a colitis flare. (case.edu)

Compared with a relatively large dataset involving organic chemical infusions (n = 53), infusion of six different nanoparticle s of diverse sizes and composition (silica or dextran coated Fe(2)O(3), silica or citrate coated silver, PEG or carboxylated quantum dots [QD]) resulted in statistically significant post-infusion flap weight gain and an increase in arterial perfusion pressure (especially with QD-PEG). (cdc.gov)

Patients with acute pancreatitis (AP) often require ICU admission, especially when signs of multiorgan failure are present, a condition that defines AP as severe . (springeropen.com)
The first dataset was a gene-expression profile that characterizes the cancer cells of a group of acute myeloid leukemia patients. (biomedcentral.com)
Conclusion: Human AAT is an acute phase protein with a broad-protease inhibitory and immunomodulatory activities used as a therapeutic for emphysema patients with inherited AAT deficiency. (lu.se)

In order to investigate acute effects of loud noise exposure on cochlear microcirculation and hearing function, we have established a new standardized animal model by using in vivo-fluorescence microscopy and auditory brainstem response. (uni-muenchen.de)

Individuals with untreated SBE can survive up to 1 year, whereas someone with acute infection that is untreated will barely survive 6-8 weeks. (medscape.com)

In addition, IL-33 treatment impaired epithelial barrier permeability in vitro and in vivo, whereas absence of ST2 enhanced wound healing response upon acute mechanical injury in the colon. (bmj.com)
artérias mesentéricas (MA) e veias (MV) foram montadas em cânulas de vidro, por via intravenosa preenchida com dextran fluorescentes e incremental pressurizado acima de seus valores fisiológicos in vivo. (bvsalud.org)

Mouse colitis associated colon cancer (CAC) was induced firstly by azoxymethane (AOM) and followed by administration of drinking water containing 5 % dextran sodium sulfate (DSS) in a cycle protocol, each cycle consisted of seven days of 5 % DSS in the drinking water and followed by seven days of regular water. (biomedcentral.com)

Dextran was discovered by Louis Pasteur as a microbial product in wine, but mass production was only possible after the development by Allene Jeanes of a process using bacteria. (wikipedia.org)
Some bacteria coproduce fructans, which can complicate isolation of the dextrans. (wikipedia.org)

In the present study spinal cord blood flow (SCBF), measured by the hydrogen clearance technique, and motor and somatosensory evoked potentials (MEP and SSEP) were recorded to evaluate whether the administration of nimodipine and dextran 40, alone or in combination, could increase posttraumatic SCBF and improve axonal function in the cord after acute SCI. (thejns.org)

Prevention of thrombosis after pelvic surgery by British dextran 70. (krombie.net)

Dextran also increases blood sugar levels. (wikipedia.org)

The hemodilution caused by volume expansion with dextran use improves blood flow, thus further improving patency of microanastomoses and reducing thrombosis. (wikipedia.org)

Bioinformatic analysis of the gene expression data identified significant enrichment of several diseases/biological function categories (for example, cancer, leukocyte migration, inflammatory response, mitosis, and movement of phagocytes) and canonical pathways (for example, kinetochore metaphase signaling pathway, granulocyte and agranulocyte adhesion and diapedesis, acute phase response, and LXR/RXR activation). (cdc.gov)

Dextran solutions are favored distending media for many hysteroscopic procedures because they are easy to administer, distribute uniformly within the uterine cavity, and are relatively nontoxic. (the-medical-dictionary.com)

ACS surrounds three clinical conditions that result from an acute imbalance between myocardial oxygen supply and demand: unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) [ 2 , 3 ]. (hindawi.com)

In conclusion, these data clearly show that TNF-α-inhibition is a promising treatment strategy in acute noise-induced hearing loss. (uni-muenchen.de)

Dextrans are available in multiple molecular weights ranging from 3 kDa to 2 MDa. (wikipedia.org)
Dextrans are available in multiple molecular weights ranging from 10,000 Da to 150,000 Da. (the-medical-dictionary.com)

Recent work has indicated that direct-current (DC) fields may promote recovery after acute spinal cord injury. (thejns.org)

14 hours long time lapse of a T cell acute lymphoblastic leukaemia (T-ALL) cells observed using confocal microscopy of live mouse calvarium bone marrow. (imperial.ac.uk)

Dextran can be used as a stabilizing coating to protect metal nanoparticles from oxidation and improve biocompatibility. (wikipedia.org)

Dextran 70 is on the WHO Model List of Essential Medicines, the most important medications needed in a health system. (wikipedia.org)

Diseases1

Chemicals and Drugs3

Iron Dextran4

Rich in dextrans1

Intravenous6

Sodium sulfate-induced2

Noncardiogenic pulmonary edema1

Larger dextrans3

Saline2

Sulfate sodium1

Produced from sucrose1

Applying osmotic1

Mice8

Fluorescent5

Induced acute colitis1

Vascular6

Sucrose2

Polysaccharide2

Inflammatory bowel d1

Chronic2

Albumin1

Linkages1

Renal failure1

Platelet1

Pathogenesis1

Syndrome2

Lengths1

Intestinal1

Infusion1

Patients3

Exposure1

Infection1

Vivo2

Drinking water1

Bacteria2

Administration1

Prevention1

Levels1

Blood flow1

Phase1

Solutions1

Result1

Treatment1

Multiple2

Recovery1

Cell1

Improve1

List1