AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, Agriculture
TriterpenesPentacyclic TriterpenesGanodermaOleanolic AcidMaytenusAlstoniaResins, PlantCelastraceaeZiziphusCommiphoraPlant ExtractsMimusopsAlismaActaeaBarringtoniaBryoniaPoriaLecythidaceaeCeanothusGardeniaReishiLycopusHippocrateaceaeLoranthaceaeLanosterolSesquiterpenes, EudesmaneSpectrophotometry, InfraredSaxifragaceaeBoswelliaAster PlantRubiaceaeMolecular StructurePolyporaceaeOenotheraMomordica charantiaMagnetic Resonance SpectroscopyTanninsCombretumPolyporalesDryopterisRehmanniaPlant LeavesDiospyrosIntramolecular TransferasesGlycosidesPlants, MedicinalSaponinsPlant StemsTerpenesSqualeneInhibitory Concentration 50Antineoplastic Agents, PhytogenicMolecular ConformationSpectrophotometry, UltravioletFruitPlant RootsImmunomodulation
SaponinsSterolsBioactiveGlycosidePolysaccharidesBetulinPentacyclic TriterpenesLupaneTriterpenoidsDerivativeMedicinalMaytenusAcidsPotentExtractExtractsIsolationCytotoxicityAcetateCompoundsSteroidsOleananeDerivativesSkeletonSqualenePossesses a wide rangeAnti-inflammatory activityFungiCompoundPhytochemicalsAntibacterialAnticancer activitiesStudyGanodermaCrudeAntiallergicAnticoagulant
Saponins7
  • Triterpenoid saponins are triterpenes which belong to the saponin group of compounds, making them triterpenoid glycosides. (wikipedia.org)
  • Four new triterpene saponins from Cephalaria speciosa and their potent cytotoxic and immunomodulatory activities. (bvsalud.org)
  • Four new triterpene saponins , namely speciosides A-D (1-4) along with six known saponins were isolated from the n-butanol extract of Cephalaria speciosa. (bvsalud.org)
  • Maesa saponins with the 13,28-epoxy-oleanane triterpene core skeleton were described recently to possess strong and selective in vitro and in vivo antileishmania activity. (uantwerpen.be)
  • A clear correlation was found between the presence of close analogue 13,28-epoxy-oleanane triterpene saponins and potent and selective antileishmania activity. (uantwerpen.be)
  • The main active agents in Panax ginseng are ginsenosides, which are triterpene saponins. (aafp.org)
  • All of the mushroom extracts were phytochemically screened and carbohydrates, reduced sugar, flavonoids, alkaloids, saponins, sterols, coumarins and triterpenes were present in all of the mushroom samples. (scialert.net)
Sterols1
  • The plant kingdom, including medicinal and dietary plants, offers many natural phytochemicals that include phenolic diterpenes, triterpenes, flavonoids, phenolic acids and sterols [ 21 - 23 ]. (ijpsonline.com)
Bioactive5
  • In the current decade, holothurians are becoming more popular among researchers due to the recently obtained data about the chemical structures and physiological activities of bioactive ingredients that are extracted from these marine invertebrates. (springer.com)
  • It has been suggested that medicinal mushrooms exhibit this broad spectrum of pharmacological activity due to the mechanisms of action of their various bioactive constituents, including immunomodulating, digestive, hepatoprotective, neuroprotective, nephroprotective, osteoprotective, and hypotensive activity. (holisticpetinfo.com)
  • Phytochemical studies showed that T. wilfordii produces diverse bioactive terpenoids with strong activities [ 4 ]. (techscience.com)
  • This is a bioactive triterpene aglycone derivative of astragaloside, an extract of Astragalus membranaceus and specifically, from its root (e.g., radix astragali). (antiaging-systems.com)
  • This study aimed to isolate and evaluate the bioactive constituents based on their biological activities. (ub.ac.id)
Glycoside2
  • There was a study conducted on the "antiproliferative activity of triterpene glycoside nutrient from monk fruit in colorectal cancer and throat cancer," but it was on colorectal and throat cancer cells in a petri dish. (nutritionfacts.org)
  • It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. (affygility.com)
Polysaccharides3
  • This product contains polysaccharides and triterpenes and can therefore boost the immune system and improve bodily functions. (euyansang.com)
  • Polysaccharides are believed to exhibit potent immunomodulatory activity - they bring balance to the immune system. (holisticpetinfo.com)
  • The reported benefits of Ganoderma lucidum may be largely ascribed to its biologically active constituent polysaccharides and triterpenes known as ganoderic acids having structural similarity to steroid hormones. (greenmedinfo.com)
Betulin3
  • In phagocyte chemiluminescence assay, betulin showed moderate inhibitory effect on the oxidative burst in the neutrophils, while addition of betulin triterpene was able to stimulate the proliferation of the phytohemagglutinin (PHA) treated human peripheral blood lymphocytes (hPBLs). (ac.ir)
  • Silver birch bark contains a large amount of the triterpene betulin and its derivative betulinic acid. (canopy.org)
  • A lupane-type triterpene derivative of betulin which was originally isolated from BETULA or birch tree. (bvsalud.org)
Pentacyclic Triterpenes1
  • Sesquiterpene lactones and pentacyclic triterpenes were the major lipophilic families, representing respectively 246% and 1089% of the detected compounds. (ua.pt)
Lupane2
  • Two new sesquiterpenes (1-2) and one new lupane triterpene (3) have been isolated from the roots of Maytenus apurimacensis. (edu.pe)
  • Komissarova Nataliya G., Belenkova Nataliya G., Shitikova Olga V., Spirikhin Leonid V., Yunusov Marat S.: Oxidative Decarboxylation of Triterpene C-28 Acids of Lupane Series. (cas.cz)
Triterpenoids1
Derivative2
  • The structure of a new triterpene derivative isolated from Poria cocos was determined to be 3 beta-p-hydroxybenzoyldehydrotumulosic acid by spectral and chemical methods. (nih.gov)
  • In another project, it was shown that a direct derivative of cycloastragenol, a compound called GRN510 which is a small proprietary molecule, also has telomerase enhancing activities. (antiaging-systems.com)
Medicinal3
  • This paper presents the current state of knowledge on the biological activity and possible medicinal applications of selected species of the genus Ganoderma: Ganoderma adspersum (Schulzer) Donk, Ganoderma applanatum (Pers. (researchgate.net)
  • The majority of published research on the medicinal activity of Panax ginseng has focused on ginsenosides. (aafp.org)
  • Antimicrobial activity of some medicinal barks used in Peruvian Amazon. (rxlist.com)
Maytenus2
Acids2
  • Antiallergic activity has been demonstrated by G. lucidum extracts, as well as some compounds isolated from this species, such as ganoderic acids, oleic acid, and cyclooctasulfur acid belonging to triterpenes [80]. (researchgate.net)
  • The two compounds described here for the first time, were named amolsamic acids A&B. The seeds and amolsamic acids showed an interesting antioxidant potential, and a strong anti-inflammatory activity on neutrophils, MPO and HRP models. (ac.be)
Potent4
  • To isolate the anticancer triterpenes with potent cytotoxicity from marine sponge, Siphonochalina siphonella and state the mode of action in cancer cell lines. (phcog.com)
  • All compounds, except 5, were tested towards MCF-7, PC-3 and A549 and showed effects with IC 50 in range 7.9-87 μM, whilst, 3 showed potent anti-proliferative activity against PC-3 and A549 with IC 50 = 7.9 ± 0.120 and 8.9 ± 0.010 μM, respectively. (phcog.com)
  • Compounds (1-4) showed significant cytotoxic activities, while 3 showed potent effect. (phcog.com)
  • However, the methanolic extract of M. chamomilla reveals potent activity against Pseudomonas sp . (sysrevpharm.org)
Extract4
  • At 50 μg mL -1 , the extract had potently induced apoptotic cell death of HCT-116 colon cancer cell line by inducing caspases 3 and 7 activity. (scialert.net)
  • There are few reports on the bioactivity and pharmacological properties of S. koetjape with fewer reports on cytotoxic activity and no reports could be found about anti-angiogenic activity of S. koetjape , thus this research was done in order to study the in vitro cytotoxic and anti-angiogenic properties of the stem bark extract of S. koetjape . (scialert.net)
  • The ethyl acetate layer and crude extract displayed the higher antimicrobial activities than n -butanol and water layer. (ub.ac.id)
  • Oleogel-S10, classified as an herbal product, contains triterpenes derived from birch bark extract, which have been formulated with sunflower oil to form a gel. (medscape.com)
Extracts12
  • The apolar fractions of the leaf and stem extracts and some isolated triterpenes showed low trypanocidal activity. (fiocruz.br)
  • Crude alcohol extracts from several plant species of Myrsinaceae, Primulaceae, Aceraceae and Icacinaceae were evaluated for in vitro activity against Leishmania infantum intracellular amastigotes and cytotoxicity on MRC-5SV2 cells, while the saponin content was evaluated qualitatively by TLC. (uantwerpen.be)
  • Interesting activities were also found in extracts that did not exactly match the TLC characteristics of the Maesa saponin references, as was the case for Ardisia angusta, A. amherstiana, A. caudata, A. gigantifolia, A. roseiflora, Myrsine affinis, Acer brevipes and A. laurinum var. (uantwerpen.be)
  • These results shown that crude ethanol and water extracts of Iris taochia had effective reducing effect, radical scavenging activity and metal chelating effects when compared to standard antioxidants. (ijpsonline.com)
  • They were then evaluated for their biological activity, together with seed extracts. (ac.be)
  • antidermatophytic activities of co coa butter, cloves essential oil, and a mixture of both extracts. (researchgate.net)
  • The plant extracts of T. wilfordii also show activities toward other diseases, such as dermatosis, renal and bowel diseases [ 2 , 3 ]. (techscience.com)
  • Teas and extracts of this plant have been used in traditional medicine as health supplements and it is known that cycloastragenol has several other effects apart from the telomerase activities (6). (antiaging-systems.com)
  • Petroleum ether, ethanol and aqueous extracts of the mushrooms were screened for their antimicrobial activity against different pathogenic bacteria and fungi. (scialert.net)
  • Antimicrobial and antibiofilm activities of aqueous extracts of Cucurbita pepo L. (bvsalud.org)
  • In the second phase of our study, the antimicrobial activity of the extracts was cut into six microbial subspecies such as Staphylococcus aureus , Bacillus thuringiensis , Escherichia coli and Fusarium sp . (sysrevpharm.org)
  • The antimicrobial activities showed by the crude extracts, fractions, and pure compounds of H. corymbosa can be used as a commercial product for antimicrobial agent against S. aureus , S. enterica , E. coli and B. substilis . (ub.ac.id)
Isolation1
Cytotoxicity1
  • The aqueous fraction, rich in Oenothein B and Gemin D/Hippomanin A, showed anti-H. pylori activity and higher cytotoxicity on AGS cells compared to the other samples analysed. (medworm.com)
Acetate2
  • 3 beta-p-hydroxybenzoyldehydrotumulosic acid showed marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)- and arachidonic acid (AA)-induced ear inflammation in mice. (nih.gov)
  • Cynaropicrin was the most abundant sesquiterpene lactone, while taraxasteryl acetate was the main pentacyclic triterpene. (ua.pt)
Compounds5
  • In phagocyte chemiluminescence assay, different concentrations of compounds were incubated with the human whole blood in triplicate and the chemiluminescence activity of phagocytic cells were measured by using serum opsonized zymosan and luminol. (ac.ir)
  • Antiinflammatory, antioxidant and anticancer activities reported to be possessed by these compounds might have resulted from prevention of oxidative damage [ 24 , 25 ]. (ijpsonline.com)
  • Ligand-based screening techniques essentially focus on comparative molecular similarity analysis of compounds with known and unknown activity, regardless of the methods or algorithms used. (benthamscience.com)
  • Simple coumarins and analogues are a large class of compounds that have attracted their interest for a long time due to their biological activities: they have shown to be useful as antitumoural, anti-HIV agents and as CNS-active compounds. (benthamscience.com)
  • This means that these compounds may increase or reduce the activities of telomerase. (antiaging-systems.com)
Steroids1
Oleanane1
  • This study indicates that the 13,28-epoxy-oleanane triterpene moiety is essential for selective antileishmania potential and that several other plant species could still be explored for antileishmania drug discovery. (uantwerpen.be)
Derivatives2
  • Not so long ago it was shown (1) that derivatives of curcumin enhance telomerase activity, both directly and indirectly. (antiaging-systems.com)
  • Dehaen Wim, Mashentseva Anastassiya A., Seitembetov Talgat S.: Allobetulin and Its Derivatives: Synthesis and Biological Activity. (cas.cz)
Skeleton2
  • Achilleol A: A new monocyclic triterpene skeleton from Achillea odorata L." Tetrahedron Letters. (wikipedia.org)
  • The novel β-dihydroagarofurans are the first sesquiterpenes with a basic polyhydroxy skeleton of 15-deoxyalatol and 4,15-dideoxyalatol that show high MDR reversing activity in the protozoan parasite Leishmania tropica. (edu.pe)
Squalene2
  • Squalene, a triterpene, was also detected in minims. (auburn.edu)
  • This study also investigated the biological activity of heptadecane and squalene on fire ant workers. (auburn.edu)
Possesses a wide range1
  • Wedelolactone possesses a wide range of biological activities and is used for the treatment of hepatitis and cirrhosis, as an. (diagnose-me.com)
Anti-inflammatory activity1
  • Alisol A has anticalcium oxalate stone function, which promotes glucose uptake and anti-inflammatory activity [ 2 , 5 , 12 ]. (hindawi.com)
Fungi1
  • Oxalate is involved in various metabolic and homeostatic mechanisms in fungi and bacteria and may play an important role in various aspects of animal metabolism, including mitochondrial activity regulation, thyroid function, gluconeogenesis, and glycolysis. (medscape.com)
Compound1
  • It is a pleiotropic compound showing antitumor, anti-inflammatory, antihypertensive and antidiabetic activities ( 15 ). (spandidos-publications.com)
Phytochemicals1
  • Different parts of this plant contain various phytochemicals that show an extensive range of biological activities. (nrfhh.com)
Antibacterial2
  • To contribute to the development of antibacterial products from propolis produced by native Brazilian bees, twenty-nine samples of propolis collected from hives in the state of Minas Gerais, Brazil, were screened for in vitro activity against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. (scielo.br)
  • Frankincense is an aromatic resin obtained from trees of the genus Boswellia and has been hypothesized to exhibit a number of health supporting properties, including the treatment of rheumatoid arthritis and anti-inflammatory, antibacterial, antifungal and anticancer activities ( 5 - 8 ). (spandidos-publications.com)
Anticancer activities1
  • The present study aimed to investigate the composition and potential anticancer activities of essential oils obtained from two species, myrrh and frankincense, by hydrodistillation. (spandidos-publications.com)
Study4
  • In the current study, the anti‑invasive activities and associated signaling pathways of celastrol were determined in ovarian cancer cells. (spandidos-publications.com)
  • The aim of this study was to investigate the influence of the hydrothermal-cooking process of soybean in combination with commercial chymosin-pepsin rennet on the content and activity of TI, urease and lectins in tofu. (medworm.com)
  • In this study, we investigated whether Ganoderma lucidum elicits its anti-tumor effects by suppressing cell growth and inducing antioxidative/detoxification activity in human ovarian OVCAR-3 cells. (greenmedinfo.com)
  • An interesting study has shown that cycloastragenol not only promotes telomerase activity, but it may also be useful in reducing depressive symptoms (7). (antiaging-systems.com)
Ganoderma2
  • However, the mechanism by which Ganoderma lucidum exerts its chemopreventive activities remains unknown. (greenmedinfo.com)
  • Chemopreventive activities elicited by Ganoderma lucidum were demonstrated by the induction of antioxidant SOD and catalase as well as the phase IIdetoxification enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) and glutathione S-transferase P1 (GSTP1) via the Nrf2 mediated signaling pathway known to provide chemoprotection against carcinogenicity. (greenmedinfo.com)
Crude1
Antiallergic2
  • Recent pharmacological studies have confirmed the known traditional uses of these species, elucidated previously unknown mechanisms of biological action, and found evidence of new biological activities, such as anticancer, cytotoxic, antiallergic, and neuroprotective activities. (researchgate.net)
  • Sesquiterpenoids (e.g., alismoxide and alismol) usually have remarkable antiallergic activity [ 15 ] and anti-inflammatory effects [ 16 , 17 ]. (hindawi.com)
Anticoagulant1
  • Furthermore they have been reported to have multiple biological activities (anticoagulant, anti-inflammatory) although all these properties have not been evaluated systematically. (benthamscience.com)