• This study was designed to test the hypothesis that genetic deletions are a marker of invasive behavior and to identify the loci most commonly involved. (ox.ac.uk)
  • This was further supported by the presence of Rb protein in two of four tumors where the genetic loss extended to include the intragenic marker D13S153. (ox.ac.uk)
  • Table 2 presents resilience factors derived from a recent review of psychosocial, biological, and genetic research. (psychiatrictimes.com)
  • Difficulties associated with obtaining such minimum evidence were illustrated by examination of the genetic polymorphism associated with the activity of N-acetyltransferase, an enzyme associated with the activation and deactivation of carcinogenic arylamines, and the risk of bladder cancer among workers exposed to such chemicals. (cdc.gov)
  • We examined genetic and metabolic markers of altered oestrogen metabolism in subjects with a BMPR2 mutation. (ersjournals.com)
  • Our genetic and biochemical results suggest that imbalanced oestrogen metabolism may contribute to the pathogenesis of FPAH, and that further analysis of this pathway may lead to new biological markers and therapeutic treatments for all forms of PAH. (ersjournals.com)
  • This study published in Communications Biology utilizes genetic data from over 400,000 adults who were enrolled in the UK Biobank revealing a clear link between walking pace and a genetic marker of biological age, leucocyte telomere length (LTL). (worldhealth.net)
  • Individual differences in responses to trauma may be determined by a complex interplay between psychological, behavioral, social, and biological factors. (psychiatrictimes.com)
  • This is why a new, first-of-its-kind national cohort study will unpack the social, cultural, behavioral, psychosocial, biological, and medical influences on post-cancer life in Latino cancer survivors to fill a crucial gap in knowledge about their survivorship experience. (uthscsa.edu)
  • The thesis is a theoretically informed empirical qualitative inquiry focusing on the complex relations between three sets of dispositional qualities: behavioral dispositions, and psychological and biological markers. (theses.cz)
  • We will not find effective cures for autism until we add biological markers to behavioral symptoms in diagnosing children. (blogspot.com)
  • Three different types of biological features can help to distinguish among the children currently labeled as autistic by behavioral symptoms. (blogspot.com)
  • Demographic characteristics, two biological variables (A1C and non-HDL cholesterol), and four behavioral management measures (kilocalories, calories of saturated fat, number of fruit and vegetable servings, and minutes of physical activity) were assessed. (diabetesjournals.org)
  • The focal point of our analysis has been the biological markers, detected as neuronal activity through an EEG check. (theses.cz)
  • Here, we report that neuronal activity enhances Nr4a2 expression and function in cultured mouse hippocampal neurons (both sexes) by an ionotropic glutamate receptor/Ca2+/cAMP response element-binding protein/CREB-regulated transcription factor 1 (iGluR/Ca2+/CREB/CRTC1) pathway. (uab.cat)
  • Over the past 50 years, more than 300 studies have explored the combined psychological and biological value of psychosocial interventions, from mindfulness to yoga to the arts, for cancer patients, survivors and carers [ 1 - 3 ]. (ecancer.org)
  • 1 This year's research has given the community a deeper understanding of the biological connections between these conditions, shared genetics, and why ASD may be part of a larger spectrum of psychiatric issues affecting children and adults. (autismsciencefoundation.org)
  • Cancer researchers will study how different issues ─ discrimination, depression, chronic stress, diet, biological markers, genetics and many more ─ impact these Latino survivors' symptom burdens, health-related quality of life and disease activity. (uthscsa.edu)
  • We do this by combining multiple modalities, including MRI, PET, fluid-based markers and genetics, to clarify the biological processes leading to neurodegenerative conditions. (lu.se)
  • We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction. (psychiatrictimes.com)
  • The IL-18 serum concentration may be used as a biological serum marker to distinguish sJIA from other febrile diseases. (scielo.br)
  • Background:Serum cathepsin B activity has been considered a potential marker of tumor progression. (medscimonit.com)
  • The aim of this study was to assess serum cathepsin activity during tumor progression and regression.Material/Methods: Of 60 female rats inoculated with Morris hepatoma cells, 45 were treated with BRT, and the remaining 15 were left without treatment. (medscimonit.com)
  • Serum cathepsin B activity was determined, tumor volumes were measured, and histological examinations of the tumor tissues were performed.Results: Of the 45 BRT-treated rats, tumor regression was observed in 31 rats, and serum cathepsin activity was analyzed in these rats. (medscimonit.com)
  • Ethical Naturals Inc (ENI) has announced the completion of two new studies to support the anti-adhesion activity efficacy of its Cranberex cranberry extract. (nutraingredients.com)
  • Naturex's launch of a new cranberry extract sees the company moving beyond proanthocyanidins (PACs) as a marker of efficacy towards anti-adhesion activity (AAA), something it sees as a more relevant biological marker of benefits to urinary tract health. (nutraingredients-usa.com)
  • Wu and colleagues 6 reviewed evidence that resilience may be associated with a host of biomarkers, including (f DHEA), neuropeptide Y (NPY), galanin, testosterone, serotonin-1A receptor, and benzodiazepine receptor function, as well as the lowest range for hypothalamic-pituitary-adrenal (HPA) axis, corticotropin-releasing hormone (CRH), and locus coeruleus-norepinephrine activity. (psychiatrictimes.com)
  • Considering the lack of reagents for ALK1 detection that has hampered the field to date, our work provides the opportunity to validate the 8-gene signature and CLEC14A as biomarkers for ALK1 activity. (lu.se)
  • It is concluded that Klein's biological model has greatly stimulated research, but recent empirical data offer insufficient support for this specific model, although biological mechanisms seem important. (tijdschriftvoorpsychiatrie.nl)
  • The purpose of this Funding Opportunity Announcement (FOA) is to encourage epidemiological, clinical and translational research that will increase our understanding of the natural history, prevalence, biological mechanisms, psychological variables, and clinical risk factors responsible for the presence of multiple chronic pain conditions in people with pain. (nih.gov)
  • The objective of this study was to evaluate clinical and microscopic features of squamous cell carcinomas using immunohistochemical analysis and assessing biological markers of angiogenesis and tumor vascular activity (anti-CD31, anti-CD34, Factor VIII), cell proliferation (Ki-67), and loss of cell suppression (p53). (bvsalud.org)
  • Furthermore, in some tumors we identified a breakpoint between markers intragenic and extragenic to the retinoblastoma gene (Rb1) on chromosome 13q, suggesting that tumor suppressor genes other than or in addition to Rb1 may be involved in pituitary tumorigenesis. (ox.ac.uk)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • Conclusion: DNA aneuploidy may be a key indicator for tumors activity and malignancy in SGTs, while the SPF has a minor role in the evaluation of SGTs activity. (researchgate.net)
  • Of these, three displayed particularly aggressive biological behavior, whereas there were no clinical details provided for the others. (ox.ac.uk)
  • We focused on possible differences between two groups of respondents - those exhibiting signs of health enhancing behavior and those inclining to health threatening behavior - in terms of constellations of relationships between the biological and the psychological markers. (theses.cz)
  • If children with autistic behaviors were evaluated for these biological features, physicians would likely find several distinct profiles among the children, despite the similarities of their behavior. (blogspot.com)
  • Drawbacks to the use of N-acetyltransferase polymorphism as a biological marker of susceptibility to cancer were discussed. (cdc.gov)
  • We also determined the urinary 2-OHE/16α-OHE 1 ratio, one biological measure of CYP1B1 activity, among a group of females nested from our polymorphism study. (ersjournals.com)
  • Our findings suggest an important contribution of tumor markers in the diagnosis and prognosis of these malignancies, as well as in treatment planning. (bvsalud.org)
  • dc.title: A Preliminary study of the invertase activity in coconut dc.contributor.author: ALLES, NH dc.description.abstract: AB : A ` particulate ` invertase preparation of low activity (sedimenting in the 900 g fraction) was extracted from the stalk and mesocarp tissues of coconut (Cocos nucifera L.). The activity o invertase was found to increase linearly with the time of incubation (0 - 3h). (who.int)
  • NeuroSense completed a Phase IIa clinical study which successfully met its safety and efficacy endpoints including reducing functional and respiratory deterioration and statistically significant changes in ALS-related biological markers indicating PrimeC's biological activity. (prnewswire.com)
  • MR-1 have better antioxidant and autoinflammatory activity than rest of CL samples due to its high concentration of polyphenols (33.68 mg/g) and curcumin (29.69 mg/g). (pucv.cl)
  • Using complex lipid mixtures derived from cellular tissue, we perform a targeted lipidomic assessment of the antioxidant activity of five plant extract supplements. (brighton.ac.uk)
  • But without some kind of change to include a measure of biological activity, we risk branding everything an antioxidant without meaning anything. (foodnavigator.com)
  • How about we settle on a definitive way of classifying antioxidant activity, and levels that could be classed as low, medium, or high in terms of antioxidants levels? (foodnavigator.com)
  • Moreover, we need to link antioxidant content to an endpoint - for example, the dose of antioxidant needed to reduce a certain biological marker linked to the risk of a specific disease, like tomato extracts and prostate specific antigen (PSA) levels in relation to prostate cancer. (foodnavigator.com)
  • Currently, antioxidant activity is based on lab assays, but do these enable us to really appreciating the potential physiological ​ benefits? (foodnavigator.com)
  • There are numerous ways of quantifying the antioxidant activity, but these are only adding to the confusion. (foodnavigator.com)
  • The antioxidant activity of selected compounds has been measured using a range of lab-based assays, including the ferric reducing ability of plasma (FRAP) assay, the oxygen radical absorbance capacity (ORAC) and Trolox equivalent antioxidant capacity (TEAC). (foodnavigator.com)
  • Objective To evaluate whether including a test for faecal calprotectin, a sensitive marker of intestinal inflammation, in the investigation of suspected inflammatory bowel disease reduces the number of unnecessary endoscopic procedures. (bmj.com)
  • The potential health benefits of North American cranberry (Vaccinium macrocarpon) and its unique nutrition profile extend beyond reducing the risk of urinary tract infections to include multiples heart health activities and temper inflammation, says a. (nutraingredients-usa.com)
  • Cranberry cooperative Ocean Spray Cranberries, Inc. is leveraging artificial intelligence (A.I.) from tech firm Canomiks to test and certify the biological efficacy of the cranberry. (nutraingredients-usa.com)
  • Inadequate efficacy similarly halted the development of agents impinging on the activity of the activin receptor-like kinase (ALK)1, a member of the transforming growth factor-β superfamily. (lu.se)
  • This is one of many papers to come out of NCI's HEAL study, an initiative designed to investigate the effects that physical activity, eating habits, weight patterns, diet, hormones, and other factors have on breast cancer prognosis. (nih.gov)
  • The aim of this research was to explore whether IL-18 can be a serological marker for the diagnosis of systemic-onset juvenile idiopathic arthritis (sJIA). (scielo.br)
  • Not all cranberry products are created equal, and knowing the precise proanthocyanidins profile is necessary in predicting their biological effects, new research has found. (nutraingredients.com)
  • Altogether, our results indicate that the iGluR/Ca2+/CREB/CRTC1 pathway mediates activity-dependent expression of Nr4a2 which is involved in glutamatergic synaptic plasticity by increasing BDNF and synaptic GluA1-AMPARs. (uab.cat)
  • We provide a new mechanism for the regulation of heart development by PITX2 isoforms through the regulation of ANF and PLOD1 gene expression and Nkx2.5 transcriptional activity. (lu.se)
  • This suggests measures such as a habitually slower walking speed are a simple way of identifying people at greater risk of chronic disease or unhealthy ageing, and that activity intensity may play an important role in optimising interventions. (worldhealth.net)
  • Results: Outcomes include objectively measured physical activity, biological markers of health, and self-report survey data at baseline, after the 6-month intervention or control period, and at a 12-month follow-up. (cdc.gov)
  • However, with an adeq battery of necf expsre blmarkers, prospective studies of en- vironmental effects on pregnancy outcomes might be possible. (cdc.gov)
  • The pattern of activity of aspartate aminotransferase enzyme (AST) following canine distalization stage in orthodontic treatment is being investigated. (scialert.net)
  • The current study which investigated the pattern of aspartate aminotransferase (AST) activity following application of force to distalize the canine (100 g) was a continuation of an earlier study by the same researcher which investigated the enzyme`s activity after the application of force to align teeth (30-60 g). (scialert.net)
  • This suggested the possibility of an SH group participating in the catalytic activity of the enzyme. (who.int)
  • Consequently, the low activity observed in the absence of mercaptoethanol was probally due in part, to an inactivation of the enzyme by quinones. (who.int)
  • Because of the detailed data on diet, physical activity and weight in the HEAL study, we were able to examine the extent to which these health behaviors altered this association. (nih.gov)
  • 16 on the CESD, had higher A1C, kilocalories, and calories of saturated fat and lower physical activity. (diabetesjournals.org)
  • Physical activity levels can have an impact on the risk of breast cancer. (who.int)
  • Although data in this area is not entirely consistent, moderate physical activity is associated with a lower risk of breast cancer. (who.int)
  • Additionally, the researchers found that brisk walking alone, regardless of how much physical activity a person does, leads to longer telomeres. (worldhealth.net)
  • Data from wrist-worn wearable activity tracking devices used to measure habitual physical activity also supported a stronger role of habitual activity intensity (e.g. faster walking) in relation to telomere length," said Dr. Paddy Dempsey a Lecturer and Research Fellow at the University of Leicester and within the NIHR Leicester Biomedical Research Centre, part of the University Hospitals of Leicester (UHL) NHS Trust, and lead author on the study. (worldhealth.net)
  • 1974. In: Biological handbooks: Biology data book, Volume III, second edition. (cdc.gov)
  • Documentation of the threshold limit values and biological exposure indices. (cdc.gov)
  • 1992. Threshold limit values for chemical substances and physical agents and biological exposure indices for 1992-l 993. (cdc.gov)
  • Biological exposure Indices. (cdc.gov)
  • Exposure to a potential fetal health hazard can be estimated through ecological assessment (e.g., testing the community water supply), questionnaires (e.g., classifying residents accord- ing to whether they drink bottled or tap water), or biological markers (e.g., testing for exposures to chemicals or solvents found in tap water). (cdc.gov)
  • In this example, a biological exposure marker (blood lead-level) was available for classifying mothers according to their exposure to lead. (cdc.gov)
  • In addition, this technology may be useful in the assessment of changes in inflammatory activity at entheses during the institution of new therapies. (medscape.com)
  • But in this study, the co-authors sought objective, biological measures that participants could not control: observations of their actual brain activity. (iese.edu)
  • Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. (cdc.gov)
  • Additionally, molecular dynamics simulations were performed to estimate stability and flexibility of best complexes, while collagenase activity colorimetric assay was carried out to study the effects of (1), (2) and (3) on collagenase. (ijpsonline.com)
  • Both the full length and truncated forms exert biological activity through CCR5, and the truncated form additionally interacts with CCR1 and CCR2b (10). (rndsystems.com)
  • Dr Chapman's work also includes examining brain activity during sleep (quantitative EEG analysis) in multiple patient groups including those with sleep disorders and mild cognitive impairment. (woolcock.org.au)
  • Pesticides can be classified based upon their biological mechanism function or application method. (wikipedia.org)
  • Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker. (ox.ac.uk)
  • This study investigated the potential of AST as a biological marker to monitor tooth movement by determining its activity in Gingival Crevicular Fluid (GCF) during bodily tooth movement (canine distalization). (scialert.net)
  • Therefore, AST has the potential as a biological marker to monitor progress of orthodontic tooth movement. (scialert.net)
  • Scans of blood flowing in the brain also revealed significant neurological activity in two regions of the brain: the ACC, where the potential costs and benefits of decisions are weighed, and the striatum, where value tends to be determined. (iese.edu)
  • Water samples treated with Gly 6 cH showed specific interactions with solvatochromic dyes, mainly Coumarin 7, such that it appears to be a potential physicochemical marker for Gly 6 cH. (bvsalud.org)
  • Introduction The research of Hatch (1) has greatly increased our understand- ing of the use and potential limitations of biological markers for adverse reproductive effects. (cdc.gov)
  • She has established a project of her own, working on large scale studies of proteins and pathways and networks of cellular lipids in biological systems. (cdc.gov)
  • Biological markers have been defined as xenobioticaly-induced variations in cellular or biochemical components in any biological system (Icen et al . (scialert.net)
  • Once these conclusions are established, we'll be well on our way to prescribing new therapies that target each child's particular biological disorder, rather than general therapies aimed at all children labeled as autistic. (blogspot.com)
  • The researchers found that activity in some regions of the brain - mainly sensor and motor regions of the brain - reflected the "cost of choice. (iese.edu)
  • In this study, where higher level of force applied was done to assess the suitability of AST as a biological marker to monitor orthodontic tooth movement. (scialert.net)
  • When presented with 24 images, the average brain in this study appeared to "shut down" - there was a marked decrease in activity in the regions that reflect value, reward or net benefits from the choice process. (iese.edu)
  • In a recent study of biological markers, subjective who met DSM-IV-TR diagnostic criteria for hypochondriasis had decreased plasma neurotrophin 3 (NT-3) level and platelet serotonin (5-HT) levels, compared to healthy control subjects. (medscape.com)
  • Saudi Journal of Biological Sciences , 28 (1), 707-716. (pucv.cl)
  • The prohibitive costs (time and financial) of random surveys for activity necessitated the development of an objective selection procedure. (scialert.net)
  • 1990. Subcommittee report on biological indicators of organ damage. (cdc.gov)
  • The justification for this was derived from data from biological psychiatry, especially the work of Donald Klein. (tijdschriftvoorpsychiatrie.nl)
  • The ability to triangulate multiple sources of surveillance data into a more comprehensive view of the HIV epidemic will be enhanced if more investment is made in better documentation and dissemination of surveillance activities and findings. (who.int)
  • During the decade following the introduction of second generation surveillance for HIV and AIDS in 2000, 1 there was a proliferation of surveillance data collection activities throughout the Asia Pacific region. (who.int)
  • Pitx2a and Pitx2c are endogenously expressed in C3H10T1/ 2 cells, and these cells express factors that differentially regulate PITX2 isoform activities. (lu.se)
  • This area of research has lagged con- siderably behind the field of developing new effect markers, such as semen analysis and early pregnancy loss. (cdc.gov)
  • Official relations may be considered for such nongovernmental organizations based on at least three years of their activities and future workplan on research and advocacy on global public health issues (paragraph 53). (who.int)
  • Dr. Ramirez created and led the NCI-funded Redes En Acción national Latino cancer research network for 20 years. (uthscsa.edu)
  • To find new cures, we need more research into the biological bases of the various types of autism. (blogspot.com)
  • Over the last few years the National Institutes of Health has greatly increased funding for such research, but it must continue to coordinate the studies at various laboratories to ensure systematic conclusions on these biological markers. (blogspot.com)
  • In doing so, the researchers discovered biological markers of choice overload in two specific parts of the brain - the anterior cingulate cortex (ACC) and the stratium - proving not just that choice overload exists but which parts of the brain are responsible for it. (iese.edu)
  • While volunteers were deciding which images to choose, their brain activity was monitored. (iese.edu)
  • In those two key regions, brain activity tended to be highest when test shoppers had 12 options to select from. (iese.edu)
  • Brain activity was lower when there were only six images - but also, interestingly, when there were 24 options. (iese.edu)
  • Unlike Heath, who associated activity in various regions of the brain as pleasure-oriented, modern theory is based on activation of the pleasure/reward system by the neurotransmitter dopamine. (drugscience.org)
  • These teams then coordinated investigation activities with the appropriate state health departments ( Figure 1 ). (cdc.gov)
  • Engineers from the University of Illinois and the Massachusetts Institute of Technology are a step closer to human-operated robotics with their two-legged unit, named Little Hermes, which can walk, run, jump and interact with the environment in synchrony with a human operator. (btn.com)
  • Menstruation is a crucial biological marker and can be used to better understand your health. (withings.com)
  • The variation in use of terms to describe different surveillance activities across countries was a key challenge. (who.int)
  • Studies have shown a 30% reduction in risk level associated with a few hours per week of vigorous activity compared to no exercise at all. (who.int)
  • This paper summarizes the progress of HIV surveillance for 20 countries in the region, covering population size estimates of key populations at higher risk, HIV case reporting, HIV sentinel surveillance and probability surveys of behavioural and biological markers. (who.int)
  • HIV sentinel surveillance (HSS) and probability surveys of risk behaviours, including those integrated with biological markers. (who.int)
  • Heart rate variability was one of the biological markers investigated. (lu.se)
  • PITX2 and Nkx2.5 are two of the earliest known transcriptional markers of vertebrate heart development. (lu.se)
  • In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Preventing Chronic Disease . (cdc.gov)
  • The researchers estimate that a lifetime of brisk walking could lead to the equivalent of 16 years younger biological age by midlife. (worldhealth.net)