• tissue
  • Craniopharyngioma is a cancer which arises in the pituitary gland, in tissue originally found in the embryo. (encyclopedia.com)
  • While they regulate asymmetric cell division and cell fate determination during early development and embryogenesis, TGF β family members play a major regulatory role in hormonal and immune responses, cell growth, cell death and cell immortalization, bone formation, tissue remodeling and repair, and erythropoiesis throughout adult life. (hindawi.com)
  • Thyroid tissue consists of follicles with stored protein called colloid, containing thyroglobulin, a precursor to other thyroid hormones, which are manufactured within the colloid. (wikipedia.org)
  • parathyroid
  • It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). (wikipedia.org)
  • In many ways, calcitonin counteracts parathyroid hormone (PTH) and vitamin D More specifically, calcitonin lowers blood Ca2+ levels in two ways: Major effect: Inhibits osteoclast activity in bones Minor effect: Inhibits renal tubular cell reabsorption of Ca2+ and phosphate, allowing them to be excreted in the urine High concentrations of calcitonin may be able to increase urinary excretion of calcium and phosphate, via actions on the kidney tubules. (wikipedia.org)
  • The parathyroid glands, of which there are 4-6, are found on the back of the thyroid glands, and secrete parathyroid hormone (PTH), which causes an increase in blood calcium levels by targeting bone, the intestine, and the kidneys. (wikipedia.org)
  • stalk
  • If originating superior to the optic chiasm, more commonly in a craniopharyngioma of the pituitary stalk, the visual field defect will first appear as bitemporal inferior quadrantanopia, if originating inferior to the optic chiasm the visual field defect will first appear as bitemporal superior quadrantanopia. (wikipedia.org)
  • The pituitary gland hangs from the base of the brain by a stalk and is enclosed by bone. (wikipedia.org)
  • regulate
  • A hormone is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour. (wikipedia.org)
  • steroid hormones
  • steroid hormones, being lipid-soluble, move through the plasma membranes of target cells (both cytoplasmic and nuclear) to act within their nuclei. (wikipedia.org)
  • The production of steroid hormones is called steroidogenesis, and involves a number of reactions and processes that take place in cortical cells. (wikipedia.org)
  • diffuse
  • Pituitary adenomas and diffuse somatomammotroph hyperplasia may result from somatic activating mutations GNAS, which may be acquired or associated with McCune-Albright syndrome. (wikipedia.org)
  • belongs to a superfamily
  • TGF β belongs to a superfamily of growth factors that also includes the activins and BMPs. (hindawi.com)
  • The CALC1 gene belongs to a superfamily of related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin. (wikipedia.org)
  • commonly
  • Special features of endocrine glands are, in general, their ductless nature, their vascularity, and commonly the presence of intracellular vacuoles or granules that store their hormones. (wikipedia.org)
  • observational
  • This study is a multicenter, open-label, observational, postmarketing surveillance study of Genentech growth hormone (GH) products in the treatment of girls with Turner syndrome in the Uni. (bioportfolio.com)
  • clinical
  • In addition to cell-type specific presentations, pituitary apoplexy (i.e., pituitary adenoma apoplexy) represents another important clinical presentation of pituitary adenomas. (healthlinkbc.ca)
  • He was the first to investigate the interactions of the two central stress hormones adrenaline and cortisol in healthy as well as sick individuals in close collaboration with Nobel Prize laureates such as Andrew V. Schally and Rita Levi Montalcini Recently, Bornstein co-developed new therapeutic approaches to diabetes in preclinical and clinical stages. (wikipedia.org)