Tumor Necrosis Factor-alphaReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IIInterleukin-1CytokinesLipopolysaccharidesInterleukin-6Cells, CulturedNecrosisNF-kappa BRNA, MessengerInterferon-gammaMacrophagesCell LineMice, Inbred C57BLSignal TransductionLymphotoxin-alphaRecombinant ProteinsMonocytesApoptosisGene Expression RegulationInflammationMice, Inbred BALB CTumor Necrosis FactorsAntibodies, MonoclonalArthritis, RheumatoidMolecular Sequence DataGene ExpressionTransforming Growth Factor alphaInterleukin-10Base SequenceDose-Response Relationship, DrugInterleukin-8Mice, KnockoutReverse Transcriptase Polymerase Chain ReactionTumor Necrosis Factor Decoy ReceptorsTime FactorsAntirheumatic AgentsDisease Models, AnimalAntigens, CDMacrophage ActivationCell Line, TumorSynovial MembraneUp-RegulationTransfectionTumor Cells, CulturedLeukocytes, MononuclearInterleukin-1betaEnzyme-Linked Immunosorbent AssayPromoter Regions, GeneticMembrane GlycoproteinsEnzyme ActivationTranscription, GeneticBlotting, WesternNeutrophilsInflammation MediatorsDrug SynergismEndotoxinsFibroblastsCell SurvivalFlow CytometryDown-RegulationMacrophages, PeritonealCell DivisionI-kappa B ProteinsT-LymphocytesImmunohistochemistryAnti-Inflammatory AgentsPentoxifyllineKineticsPlasminogen Activator Inhibitor 1PhosphorylationEndothelium, VascularReceptors, Cell SurfaceTissue Plasminogen ActivatorI-kappa B KinaseLiverNitric OxideTNF Receptor-Associated Factor 2Mice, Inbred C3HInterleukin-12Urokinase-Type Plasminogen ActivatorDNA-Binding ProteinsTranscription Factor RelAImmunoglobulin GIntercellular Adhesion Molecule-1Protein BindingTranscription FactorsGranulocyte-Macrophage Colony-Stimulating FactorTumor Markers, BiologicalLungTumor Necrosis Factor Receptor-Associated Peptides and ProteinsMitogen-Activated Protein KinasesAmino Acid Sequencep38 Mitogen-Activated Protein KinasesEnzyme InhibitorsAntigens, CD14Polymerase Chain ReactionTNF-Related Apoptosis-Inducing Ligand