• Dr. Aufderheide is a nationally and internationally recognized researcher in the field of cardiac resuscitation and emergency cardiac care. (citizencpr.org)
  • This intervention limits neurologic injury associated with brain ischemia during a cardiac arrest and reperfusion injury associated with resuscitation. (medscape.com)
  • In some cases, the combination of an accessory pathway and abnormal heart rhythms can trigger ventricular fibrillation, a leading cause of sudden cardiac death. (wikipedia.org)
  • Collaboration among citizens, professionals, communities, and organizations is key to survival from sudden cardiac arrest. (citizencpr.org)
  • Since its inception, CCPRF has sought to "strengthen the Chain of Survival," a metaphor used to define the "series of actions" that improves the chance of survival for thousands of victims of sudden cardiac arrest. (citizencpr.org)
  • Sudden cardiac death (SCD) is an unexpected death due to cardiac causes that occurs in a short time period (generally within 1 hour of symptom onset) in a person with known or unknown cardiac disease. (medscape.com)
  • Interplay of various risk factors that can lead to sudden cardiac death. (medscape.com)
  • In general, advanced cardiac life support (ACLS) guidelines should be followed in all cases of sudden cardiac arrest (SCA). (medscape.com)
  • Notably, autonomic stimulation is also a potent modulator of cardiac electrophysiology. (aerjournal.com)
  • Normally, cardiac neurohormonal regulation is accomplished through the balanced effects of sympathetic and parasympathetic autonomic stimulation, along with the hormonal regulation of the renin-angiotensinaldosterone system (RAAS). (aerjournal.com)
  • This review will attempt to provide a state-of-the-art on the potential antiarrhythmic efficacy of renal artery denervation, spinal cord stimulation and direct vagal stimulation. (aerjournal.com)
  • He also designed the first catheter-electrode for cardiac stimulation. (wikidoc.org)
  • The treatment goals for patients with coronary artery atherosclerosis are to relieve symptoms of coronary artery disease (CAD) and to prevent future cardiac events, such as unstable angina, AMI, and death. (medscape.com)
  • The past 4 decades have witnessed tremendous progress in the areas of acute cardiac care, coronary care unit expansion, thrombolytic usage, and PCI. (medscape.com)
  • Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. (bvsalud.org)
  • Additionally, the patients receiving these drugs may have a lower dysrhythmic threshold resulting from underlying cardiac conditions as well as other comorbidities, making them more suscpetible to toxicity. (medscape.com)
  • Typically, patients with CAD are first seen after they present with a cardiac event. (medscape.com)
  • Autonomic and hormonal input modulate multiple facets of cellular electrophysiology - action potential duration, ion channel kinetics and intracellular calcium dynamics (just to name a few) - which translate into macroscopic manifestations of autonomic modulation such as heart rate variability, atrioventricular (AV) conduction time and QT interval variability. (aerjournal.com)
  • Antidysrhythmics alter the propagation and mechanisms of cardiac rhythms, making toxicity from these agents highly lethal. (medscape.com)
  • We review the existing evidence of brainstem involvement in the course of Covid-19, its main mechanisms, diagnostic strategies, and potential outcomes. (scientificarchives.com)
  • Action based on best practices in science, education, and implementation improves outcomes. (citizencpr.org)
  • The list of chemicals that have the potential for use as a terrorist weapon is extensive, and clinical presentation of poisoning from chemicals can be similar to that of common diseases (e.g., gastroenteritis). (cdc.gov)
  • Here, we present the clinical spectrum, the diagnostic methods, and the potential pathogenesis of the COVID-19 that result from brainstem dysfunctions. (scientificarchives.com)
  • Electrical activity in the normal human heart begins when a cardiac action potential arises in the sinoatrial (SA) node, which is located in the right atrium. (wikipedia.org)
  • 4 In reality, the intrinsic cardiac nervous system, composed of several ganglia located primarily posterior to the atria, likely acts as a 'little brain' of the heart - it provides efferent input to the myocardium, collects afferent signals on a beat-to-beat basis and performs some integrative functions on its own, all under the tonic modulation of extrinsic sympathetic and parasympathetic input (see Figure 1 ). (aerjournal.com)
  • It was long after the concept of heart block from Chinese physician Pien Ch'io that the treatment was sought, due to the scarce knowledge of the details of the cardiac conduction. (wikidoc.org)
  • In 1957 Dr. William L. Weirich's publication demonstrated the restoration of heart rate , cardiac output , and mean aortic pressures in animals with complete heart block through the use of a myocardial electrode. (wikidoc.org)
  • 3-6 At the heart of this debate is the contest between those postulating fibrillation is maintained in a deterministic way, via the action of functional re-entrant drivers known as rotors, against the notion that fibrillation is sustained by more random forces, specifically multiple electrical wavelets stochastically wandering around the heart. (aerjournal.com)
  • Feature papers represent the most advanced research with significant potential for high impact in the field. (mdpi.com)
  • Development of Methods for Mapping Bioelectronic Adjustable Measurements as potential new Therapeutics for these eight subcellular causes of chronic metabolic diseases. (pharmaceuticalintelligence.com)
  • It is anticipated that it will have a potential impact on the future of Pharmaceuticals to be used, a change from the present time current treatment protocols for Metabolic Dysfunctional Diseases. (pharmaceuticalintelligence.com)
  • Although this evidence was obtained from studies conducted largely in parallel in the fields of cardiology and psychiatry, the potential contribution of n-3 fatty acid deficiency to increased CHD morbidity and mortality in MDD has been postulated previously [ 22 , 23 ]. (hindawi.com)
  • Our studies show that genetic deletion of α2δ-1 eliminates GBP's neuroprotective effects, confirming a specific site of action. (eneuro.org)
  • Antidysrhythmic medications are widely used to treat or prevent abnormalities in cardiac rhythms. (medscape.com)
  • A pacemaker (or artificial pacemaker , not to be confused with the heart's natural pacemaker ) is an electronic device which is used to treat cardiac arrhythmias . (wikidoc.org)
  • The evolution of ECCU into the Cardiac Arrest Survival Summit will continue to provide the quality content and speakers you expect, and now include action-oriented programs and dynamic new content that brings together a broader range of partners working on initiatives to INFORM, MOTIVATE AND ACTIVATE our global community. (citizencpr.org)
  • The goals of therapy should include arresting atherosclerosis or even reversing its progression. (medscape.com)
  • Today's survival rate after out of hospital cardiac arrest is generally less than 10 percent. (citizencpr.org)
  • In the ATRIA study, it was estimated that 2.3 million adults in the United States had AF in 1996 and 1997, and that this will increase to 5.6 million by the year 2050, with more than 50 percent being more than 80 years of age [ 11 ]. (medilib.ir)
  • Nevertheless, prevention of cardiac events is likely to have the largest impact on decreasing the burden of atherosclerosis. (medscape.com)
  • 1 The core of Heisenberg's Copenhagen doctrine was the idea that the statistical character of the new quantum theory established the final failure of causal determinism, because the new uncertainty principle established that although the precise momentum and velocity of subatomic particles could never be predicted from current behaviour, highly accurate probability distributions for potential particle behaviours could be precisely defined. (aerjournal.com)
  • 1 Therefore, it is no surprise that neurohormonal regulation of cardiac electrophysiology is an area of active investigation for its potential antiarrhythmic effects. (aerjournal.com)
  • In order to exploit the pharmacological potential of natural bioactive molecules with low water solubility, such as curcumin, it is necessary to develop formulations, such as amorphous polymer dispersions, which allow a constant release rate and at the same time avoid possible toxicity effects of the crystalline form of the molecule under scrutiny. (ibecbarcelona.eu)
  • Sasson C, Haukoos JS, Bond C, Rabe M, Colbert SH, King R, Sayre M, Heisler M. Barriers and facilitators to learning and performing cardiopulmonary resuscitation in neighborhoods with low bystander cardiopulmonary resuscitation prevalence and high rates of cardiac arrest in Columbus, OH. (citizencpr.org)
  • Every two years, the Citizen CPR Foundation holds its international Cardiac Arrest Survival Summit, formerly the Emergency Cardiovascular Care Update (ECCU), which features the latest information and trends in cardiopulmonary Resuscitation. (citizencpr.org)
  • We must turn our attention to understanding how the lived experience of lay responders can help evolve our approaches to communicating about, training for and encouraging bystander CPR and protecting the mental health of those who witness an out-of-hospital cardiac arrest. (citizencpr.org)
  • In a population of patients with known ventricular arrhythmias, individuals who had ventricular fibrillation were more likely to have underlying significant heart disease (eg, cardiac tumors, long QT syndrome, structural congenital heart disease) than patients with ventricular tachycardia. (medscape.com)
  • Objective: We hypothesized that increased risk of triggered arrhythmias 1 day after DE exposure is mediated by airway sensory nerves bearing transient receptor potential (TRP) channels [e.g., transient receptor potential cation channel, member A1 (TRPA1)] that, when activated by noxious chemicals, can cause a centrally mediated autonomic imbalance and heightened risk of arrhythmia. (nih.gov)
  • For secondary prophylaxis, ICD placement is indicated as initial therapy in survivors of cardiac arrest due to ventricular fibrillation (VF) or hemodynamically unstable ventricular tachycardia (VT). (medscape.com)
  • An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart. (lookformedical.com)
  • Electrical activity in the normal human heart begins when a cardiac action potential arises in the sinoatrial (SA) node, which is located in the right atrium. (wikipedia.org)
  • They are found in cardiac myocyte membranes, the sinoatrial node, Purkinje cells of the heart and the central nervous system. (lookformedical.com)
  • A permanent pacemaker is an implanted device that provides electrical stimuli, thereby causing cardiac contraction when intrinsic myocardial electrical activity is inappropriately slow or absent. (medscape.com)
  • The concern over these multiple respiratory effects coincides with a growing awareness that wDE exposure causes adverse cardiac events as well, particularly in people who have underlying diseases such hypertension and heart disease. (nih.gov)
  • SAN DIEGO, Calif. - The Citizen CPR Foundation is proud to unveil the 40 Under 40 Class of 2023 honorees ahead of the Cardiac Arrest Survival Summit, which takes place at the award-winning Town and Country Resort, Nov. 29-Dec. 2. (citizencpr.org)
  • This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. (lookformedical.com)
  • Such cardiotoxicity might involve an inhibition of cardiac L-type Ca2+ current (ICa,L). This study was designed to define the mechanism of bupivacaine inhibition of ICa,L. METHODS: Cardiomyocytes were enzymatically dispersed from hamster ventricles. (nih.gov)
  • The diagnostic yield of genetic testing for inherited cardiac diseases is up to 40% and is primarily indicated for screening of at-risk relatives. (cdc.gov)
  • The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. (lookformedical.com)
  • Feature papers represent the most advanced research with significant potential for high impact in the field. (mdpi.com)
  • indicated that wDE could affect cardiac function in humans with preexisting heart disease. (nih.gov)
  • Strategic Marketing has aimed as an buy the dolls to Strategic Marketing Management for potentials on Marketing and Business competition lists. (3er-schmiede.de)
  • 1 Moving knowledge-to-action is the future of the resuscitation movement. (citizencpr.org)
  • As this review will highlight, cryopreservation now holds the potential to strongly benefit several areas of medicine by increasing the ease with which therapeutic cells, tissues, and organs can be stored. (biomedcentral.com)
  • 5 Unfortunately, there is no current consensus on how the extracellular potential gradient relates to the transmembrane potential gradient. (bmj.com)
  • Accordingly, our results suggest that μMS has the potential of stimulating target nuclei in the brain without affecting the surrounding white matter tracts. (frontiersin.org)