• cell
  • For example, cell division, endocytosis, axon pathfinding, embryonic development, wound healing and T-cell antigen recognition all depend on the highly dynamic nature of the actin cytoskeleton. (biologists.org)
  • Thus, the diverse array of stimuli that individually stimulate chemotaxis, cell spreading and neurite extension promote the formation of similar F-actin structures. (biologists.org)
  • site
  • The exact mechanism mediating the final scission of the intercellular bridge connecting the dividing cells is not fully understood, but requires the local constriction of endosomal sorting complex required for transport (ESCRT)-III-dependent helices, as well as remodelling of lipids and the cytoskeleton at the site of abscission. (actindynamics.net)
  • While the microtubules of the intercellular bridge are cut by the ESCRT-associated enzyme Spastin, the mechanism that clears F-actin at the abscission site is unknown. (actindynamics.net)