• QUIN
  • We investigated the relationship between inflammation, neuronal loss, and expression of indoleamine 2, 3-dioxygenase (IDO) and quinolinic acid (QUIN) in the retina of subjects with type 1 diabetes (T1D) and type 2 diabetes (T2D) and in the retina of rats with T1D. (arvojournals.org)
  • KYNA
  • While astrocytes are not able to produce quinolinic acid directly, they are capable of producing KYNA, which when released from the astrocytes can be taken in by migroglia that can in turn increase quinolinic acid production. (wikipedia.org)
  • Tissue factor (TF), its inhibitor (TFPI), prothrombin fragment 1+2 (F(1+2)), urokinase-type plasminogen activator (uPA), its soluble receptor (suPAR), plasmin/antiplasmin (PAP) complexes, KYN, kynurenic (KYNA) and quinolinic (QA) acids levels were significantly higher, whereas TRP was significantly lower in the PD patients than in the controls. (biomedsearch.com)