• types of seizures
  • Dorzolamide Methazolamide Brinzolamide dichlorphenamide Acetazolamide is effective in the treatment of most types of seizures, including generalized tonic-clonic and focal seizures and especially absence seizures, although it has limited utility because tolerance develops with chronic use. (wikipedia.org)
  • orally
  • Acetazolamide is pregnancy category B3 in Australia, which means that studies in rats, mice and rabbits in which acetazolamide was given intravenously or orally caused an increased risk of fetal malformations, including defects of the limbs. (wikipedia.org)
  • inhibitors
  • There are many effective inhibitors of CAs, most of classical sulfonamides/sulfamates CA inhibitors and their derivatives, such as ethoxzolamide (EZA), acetazolamide (AZA), do not have a good selectivity of CA-IX, over the sulfonamide-avid against iso-zyme CA-II [8- (thefreedictionary.com)
  • hydrogen
  • The electrostatic interaction had a significant effect on the binding process of acetazolamide-trypsin, whereas interaction of the acetazolamide-pepsin was driven by hydrogen bonding and van der Waals force. (springer.com)