• Codeine
  • On a dose-by-dose basis tramadol has about one tenth the potency of morphine and is approximately equally potent when compared with pethidine and codeine. (wikipedia.org)
  • Cimetidine may decrease the effects of CYP2D6 substrates that are prodrugs, such as codeine, tramadol, and tamoxifen. (wikipedia.org)
  • Then, if complete pain relief is not achieved or disease progression necessitates more aggressive treatment, a weak opioid such as codeine, dihydrocodeine or tramadol is added to the existing non-opioid regime. (wikipedia.org)
  • Phenyltoloxamine is widely used in preparations as an enhancing agent for some analgesics and antitussives (acetaminophen, dihydrocodeine, codeine, hydrocodone). (wikipedia.org)
  • citation needed] Phenyltoloxamine is one of the more effective potentiators of codeine and derivatives such as ethylmorphine, dihydrocodeine, oxycodone, nicocodeine, hydrocodone and similar drugs like tramadol and propoxyphene for all indications, pain relief and cough suppression in particular. (wikipedia.org)
  • Tramadol is structurally closer to venlafaxine than to codeine and delivers analgesia by not only delivering "opioid-like" effects (through mild agonism of the mu receptor) but also by acting as a weak but fast-acting serotonin releasing agent and norepinephrine reuptake inhibitor. (wikipedia.org)
  • opioid
  • Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain. (wikipedia.org)
  • There are suggestions that chronic opioid administration may induce a state of immune tolerance, although tramadol, in contrast to typical opioids, may enhance immune function. (wikipedia.org)
  • Some authors challenge the pharmacological validity of the step and, pointing to their higher toxicity and low efficacy, argue that a weak opioid, with the possible exception of tramadol due to its unique action, could be replaced by smaller doses of a strong opioid. (wikipedia.org)
  • Buprenorphine is a partial agonist of the μ-opioid receptor, and tramadol is a serotonin norepinephrine reuptake inhibitor (SNRI) with weak μ-opioid receptor agonist properties. (wikipedia.org)
  • Tapentadol, with some structural similarities to tramadol, presents what is believed to be a novel drug working through two (and possibly three) different modes of action in the fashion of both a traditional opioid and as a SNRI. (wikipedia.org)
  • Dosing of all opioids may be limited by opioid toxicity (confusion, respiratory depression, myoclonic jerks and pinpoint pupils), seizures (tramadol), but opioid-tolerant individuals usually have higher dose ceilings than patients without tolerance. (wikipedia.org)
  • dose of traMADol
  • Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. (drugs.com)
  • Concomitant
  • GENERALLY AVOID: Concomitant use of phenylpiperidine opioids, tapentadol, or tramadol with each other or with other serotonergic agents may potentiate the risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5-HT1A and 2A receptors. (drugs.com)
  • Concomitant other forms of tramadol, acetaminophen or carbamazepine: not recommended. (cancertherapyadvisor.com)
  • Pharmaceutical
  • Tramadol was launched and marketed as "Tramal" by the German pharmaceutical company Grünenthal GmbH in 1977 in West Germany, and 20 years later it was launched in the UK, US, and Australia. (wikipedia.org)
  • alcohol
  • Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. (drugs.com)
  • You should avoid or limit the use of alcohol while being treated with traMADol. (drugs.com)
  • Taking Tramadol
  • order cheap tramadol online Come on Taking Tramadol and Herceptin together out the front door if you're going," said Mary. (anshcarpets.com)
  • Its use during lactation is also generally advised against, but a small trial found that infants breastfed by mothers taking tramadol were exposed to about 2.88% of the dose the mothers were taking. (wikipedia.org)
  • known
  • And it was the glory of the little town being a little town that they somehow let it be known that every one was expected to look in at Mary's that night tramadol hci for dogs All about tramadol repent. (anshcarpets.com)