• metabolism
  • ALDH2, which has a lower KM for acetaldehydes than ALDH1 and acts predominantly in the mitochondrial matrix, is the main enzyme in acetaldehyde metabolism and has three genotypes. (wikipedia.org)
  • While the causes of a hangover are still poorly understood, several factors are known to be involved including acetaldehyde accumulation, changes in the immune system and glucose metabolism, dehydration, metabolic acidosis, disturbed prostaglandin synthesis, increased cardiac output, vasodilation, sleep deprivation and malnutrition. (wikipedia.org)
  • ALDH2
  • Alcohol consumption increases blood and salivary acetaldehyde levels, especially in individuals with ALDH2 polymorphisms, which are highly associated with the risk of squamous cell carcinomas in the upper aerodigestive tract. (mdpi.com)
  • The oxidation of acetaldehyde to acetate can be summarized as follows: Acetaldehyde + NAD+ + Coenzyme A ↔ Acetyl-CoA + NADH + H+ In humans, there are three known genes which encode this enzymatic activity, ALDH1A1, ALDH2, and the more recently discovered ALDH1B1 (also known as ALDH5). (wikipedia.org)
  • oxidation
  • The reaction is conducted at 90-95 °C, and the acetaldehyde formed is separated from water and mercury and cooled to 25-30 °C. In the wet oxidation process, iron(III) sulfate is used to reoxidize the mercury back to the mercury(II) salt. (wikipedia.org)
  • CH3CHO
  • This process typically is conducted over a silver catalyst at about 500-650 °C. CH3CH2OH + ​1⁄2 O2 → CH3CHO + H2O This method is one of the oldest routes for the industrial of preparation of acetaldehyde. (wikipedia.org)
  • Traditionally, acetaldehyde was produced by the partial dehydrogenation of ethanol: CH3CH2OH → CH3CHO + H2 In this endothermic process, ethanol vapor is passed at 260-290 °C over a copper-based catalyst. (wikipedia.org)
  • reactive
  • Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA, including DNA adducts, single- and/or double-strand breaks (DSBs), point mutations, sister chromatid exchanges (SCEs), and DNA-DNA cross-links. (mdpi.com)
  • mainly
  • An NBO study at these chemistry levels complemented these findings and assigned the eclipsed acetaldehyde preference mainly to the vicinal antiperiplanar hyperconjugative interactions. (mdpi.com)
  • Sherry
  • 1,1-Diethoxyethane (acetaldehyde diethyl acetal) is a major flavoring component of distilled beverages, especially malt whisky and sherry. (wikipedia.org)
  • In sensory terms, 1,1-diethoxyethane and other acetals, acetoin, and sotolon are the main compounds formed from acetaldehyde in Sherry wines. (wikipedia.org)
  • The sensory threshold for acetaldehyde is 100-125 mg/L. Beyond this level it imparts a sherry type character to the wine which can also be described as green apple, sour and metallic. (wikipedia.org)
  • pathways
  • We also give attention to research on acetaldehyde-mediated DNA repair pathways such as the Fanconi anemia pathway and refer to our studies on the prevention of acetaldehyde-mediated DNA damage. (mdpi.com)
  • vinyl alcohol
  • The tautomeric interconversion between the more stable eclipsed acetaldehyde and vinyl alcohol has been achieved through a four-membered ring transition state (TS). (mdpi.com)
  • At room temperature, acetaldehyde (CH3CH=O) is more stable than vinyl alcohol (CH2=CHOH) by 42.7 kJ/mol: Overall the keto-enol tautomerization occurs slowly but is catalyzed by acids. (wikipedia.org)
  • consumption
  • Based on extensive epidemiological evidence, the International Agency for Research on Cancer defined acetaldehyde associated with the consumption of alcoholic beverages as a "group 1 carcinogen" (definite carcinogen) for the esophagus and/or head and neck. (mdpi.com)
  • name
  • IUPAC name: ethenol): CH3CH=O ⇌ CH2=CHOH ∆H298,g = +42.7 kJ/mol The equilibrium constant is 6×10−7 at room temperature, thus that the relative amount of the enol form in a sample of acetaldehyde is very small. (wikipedia.org)
  • The systematic name of this enzyme class is (indol-3-yl)acetaldehyde:oxygen oxidoreductase. (wikipedia.org)
  • industry
  • And thanks to the support and assistance from Acetaldehyde industry chain related technical experts and marketing experts during Research Team survey and interviews. (pitchengine.com)