• laparoscopic
  • We present a case of an elderly white female with a known history of idiopathic thrombocytopenic purpura (ITP) presenting with symptoms consistent with a bowel obstruction, who was diagnosed with a wandering spleen and subsequently developed an ITP exacerbation requiring laparoscopic splenectomy. (sages.org)
  • functional
  • The spleen is also involved in the functional maturation of antibodies and is a significant reservoir for both B and T lymphocytes. (medscape.com)
  • result
  • Removal of the spleen may be undertaken as a result of being involved in a neoplastic processor as a staging procedure in some cancers. (medscape.com)
  • normal
  • In mice that lack critical transcription factors (eg, BAPX1, HOX11), development of the normal left-right axis is disrupted, and no spleen is formed. (medscape.com)
  • development
  • In humans, the spleen is the site for early hematopoietic development, particularly the development of erythrocytes during the first 4 months' gestation. (medscape.com)
  • blood
  • The function of the spleen is to remove or filter out any waste products, break down old blood cells, and produce white blood cells to help the body fight infections. (epainassist.com)
  • The spleen participates in the destruction of all 3 blood elements (erythrocytes, leukocytes, and platelets) when they reach senescence. (medscape.com)