• Accessory spleen, which results from a failure of the embryonic splenic anlage to fuse and extreme lobulation that separates splenic tissue, is a normal variant observed in 10%-30% of individuals [ 7 ]. (e-ultrasonography.org)
  • Intrapancreatic accessory spleen (IPAS) may mimic pancreatic neoplasms, but requires no further treatment. (e-ultrasonography.org)
  • Asplenia is the absence of spleen and/or its functions. (medscape.com)
  • Absence of splenic tissue can be total (congenital asplenia) or partial (hypoplastic) from birth. (medscape.com)
  • Asplenia refers to absence of the spleen thereby leading to deficient splenic function. (radiopaedia.org)
  • Although considered a nonvital organ, and once thought to serve no practical purpose, the spleen is now recognized as an important secondary lymphoid organ in immune defense and as a filter for the bloodstream. (medscape.com)
  • After birth, the spleen has several important functions as a secondary lymphoid organ and as a reservoir and filter for cells and platelets. (medscape.com)
  • The spleen, sometimes called "the forgotten organ" of the abdomen, has received less attention than other abdominal solid organs, as splenic diseases are less common and frequently clinically asymptomatic [ 1 ]. (e-ultrasonography.org)
  • Techniques include suturing the spleen to the surrounding structures, wrapping the organ in omentum or mesh prior to suture fixation, or placing it in a surgically created retroperitoneal pouch. (medscape.com)
  • Curcumin supplementation for 12 weeks significantly increased AApoAII amyloid deposition relative to controls, especially in the liver and spleen. (elifesciences.org)
  • Removal of the spleen may be undertaken as a result of being involved in a neoplastic processor as a staging procedure in some cancers. (medscape.com)
  • In cases of torsion of a wandering spleen, splenopexy with splenic salvage is the procedure of choice in the well-perfused, noninfarcted spleen. (medscape.com)
  • The spleen plays an important role in granulocyte homeostasis also by influencing the elimination of senescent cells and regulatory effects on granulocyte renewal in the bone marrow. (medscape.com)
  • The red pulp of the spleen is designed as an efficient filtering system that serves as an important scavenger. (medscape.com)
  • The vagus nerve (or wandering nerve) is one of the most important nerves in our body. (vancouveryogareview.com)
  • In mice that lack critical transcription factors (eg, BAPX1, HOX11), development of the normal left-right axis is disrupted, and no spleen is formed. (medscape.com)
  • The normal spleen shows a uniform echotexture similar to or slightly more hyperechoic than the liver or renal parenchyma. (e-ultrasonography.org)
  • Autosplenectomy is the process where the spleen loses its function due to multiple and repeated infarctive episodes, as in sickle hemoglobinopathies. (medscape.com)
  • Occasionally, the spleen may be removed to address the sheer mass effect of a massive enlargement (such as in storage disorders), which can cause mass effects. (medscape.com)
  • US reveals a small (1-3 cm), separated, well-circumscribed, round to oval mass with echogenicity identical to that of the spleen ( Fig. 2 ). (e-ultrasonography.org)
  • The spleen participates in the destruction of all 3 blood elements (erythrocytes, leukocytes, and platelets) when they reach senescence. (medscape.com)
  • this purposely infarcts the remaining spleen and minimizes blood loss, which otherwise can be quite profuse in these difficult dissections. (medscape.com)
  • Intraoperative ligation of the splenic artery at the superior margin of the pancreas in the lesser sac is another alternative to minimize blood loss if the spleen is enlarged. (medscape.com)
  • The white pulp of the spleen contains germinal centers, with lymphocytes, plasma cells, and macrophages that help coordinate the immune response and play roles in both innate and adaptive immunity. (medscape.com)
  • The spleen may be removed in other conditions (eg, hemoglobinopathies) to improve the red cell life expectancy. (medscape.com)
  • In the absence of an examination of the corpse and an inspection of the weapon, even if it is a genuine homicide case, the suspect's life cannot be taken away arbitrarily without proof of guilt. (utah.edu)
  • Abnormalities of the spleen may be classified on a pattern-oriented approach, based on splenic imaging. (medscape.com)
  • These men, with the exception of Maurer and Gotte, believed there was a definite relation between the embryonic spleen and pancreas, and consequently considered 'the spleen as being dependent upon the endodermal cells which are given off from the primitive diverticulum of the pancreas. (edu.au)
  • Children with severe Zellweger spectrum disorder also develop life-threatening problems in other organs and tissues, such as the liver, heart, and kidneys, and their liver or spleen may be enlarged. (medlineplus.gov)
  • This is a stimulating color which can be given to the spleen, liver, kidneys, heart and indeed to any organ which helps to promote good circulation. (motherjai.com)
  • Intraoperative ligation of the splenic artery at the superior margin of the pancreas in the lesser sac is another alternative to minimize blood loss if the spleen is enlarged. (medscape.com)
  • Abnormalities of the spleen may be classified on a pattern-oriented approach, based on splenic imaging. (medscape.com)
  • A congenital or acquired condition in which the SPLEEN is not in its normal anatomical position but moves about in the ABDOMEN . (nih.gov)
  • Afección, congénita o adquirida, en la que el BAZO no se encuentra en su posición anatómica normal sino que se situa en otros sitios del ABDOMEN. (bvsalud.org)
  • Because there is little or absolutely nothing to hold it in position the spleen "wanders" in the reduced abdomen or pelvis where it might be misinterpreted for an unidentified stomach mass. (valleyfamilymedicineurgentcarecenter.com)
  • This is due to laxity or absence of suspensory ligaments which normally provide peritoneal attachments to keep the SPLEEN in a fixed position. (nih.gov)
  • In some cases, where hemodynamic stability and absence of peritoneal signs afforded observation, splenectomy was delayed. (ima.org.il)
  • In humans, the spleen is the site for early hematopoietic development, particularly the development of erythrocytes during the first 4 months' gestation. (medscape.com)
  • The signs and symptoms of severe Zellweger spectrum disorder are due to the absence of functional peroxisomes within cells. (medlineplus.gov)
  • Non-Traumatic Rupture of Spleen: Can Splenectomy be Applied Selectively? (ima.org.il)
  • Non-traumatic rupture of the spleen is a rare condition. (ima.org.il)
  • Spontaneous" rupture of spleen should be suspected when abdominal symptomatology occurs against a background of an acute infectious disease, especially in young males, or a disease known to affect target organs of the reticular endothelial system. (ima.org.il)
  • C34458 Intracranial Aneurysm C99147 Neonatal Research Network Terminology C101024 Colon Atresia Colon Atresia Congenital Atresia of Colon A congenital malformation characterized by the absence of a normal opening in a part of the colon. (nih.gov)
  • C97171 Congenital Gastrointestinal Disorder C99147 Neonatal Research Network Terminology C101025 Duodenal Atresia Duodenal Atresia Congenital Atresia of Duodenum A congenital malformation characterized by the absence of a normal opening in a part of the duodenum. (nih.gov)
  • C98828 Small Intestine Atresia C99147 Neonatal Research Network Terminology C101026 Ileal Atresia Ileal Atresia Congenital Atresia of Ileum A congenital malformation characterized by the absence of a normal opening in a part of the ileum. (nih.gov)
  • Up to 30% of platelets are stored within the average spleen and can be released in response to specific stimuli such as epinephrine. (eurekaselect.com)
  • Occasionally, the spleen may be removed to address the sheer mass effect of a massive enlargement (such as in storage disorders), which can cause mass effects. (medscape.com)
  • Gotten" straying spleen could occur during their adult years because of injuries or rest hidden problems that might deteriorate the ligaments that hold the spleen in its typical position (e.g., connective cells condition or pregnancy). (valleyfamilymedicineurgentcarecenter.com)
  • It can occur in a pathological spleen caused by any of a variety of diseases. (ima.org.il)
  • For an infarcted spleen with any of the above-mentioned complications, splenectomy is required. (medscape.com)
  • Whereas a unilocular abscess can be managed successfully in select cases with percutaneous catheter drainage, some authors advocate splenectomy in all cases of splenic infarct and abscess, questioning the utility of preserving the residual, partially functioning spleen. (medscape.com)
  • In 1590, Dr. Viard used a string to stitch a segment of the spleen that had come become exposed due to a small abdominal wound and performed the first partial splenectomy. (eurekaselect.com)
  • Removal of the spleen may be undertaken as a result of being involved in a neoplastic processor as a staging procedure in some cancers. (medscape.com)
  • The major known functions of spleen are removal of aging erythrocytes and recycling of iron, elicitation of immunity, and supply of erythrocytes after hemorrhagic shock and removes intraerythrocyte inclusions. (eurekaselect.com)
  • After three months' wanderings, he was murdered by two of his companions, in the prairies of Texas, near the western branch of the Trinity River. (accessgenealogy.com)
  • Our current understanding spleen development is a significantly more accurate description. (edu.au)
  • To anyone looking over the literature on the development of the mammalian spleen the necessity for more work on the finer details of the process is evident. (edu.au)
  • Autosplenectomy is the process where the spleen loses its function due to multiple and repeated infarctive episodes, as in sickle hemoglobinopathies. (medscape.com)
  • Wandering through the neck and torso, the vagus nerve communicates vital information from the brain to the heart and intestines. (anatomy-medicine.com)
  • The white pulp of the spleen contains germinal centers, with lymphocytes, plasma cells, and macrophages that help coordinate the immune response and play roles in both innate and adaptive immunity. (medscape.com)
  • Numbness in all nerves in evening, and in tongue, with dullness of head and absence of thought. (homeoint.org)
  • It was not just the absence of fathers, uncles, brothers, but the presence in the hotel grounds of oddly damaged things: a blind cat, a broken wheelbarrow, a man who had been at Dunkirk and did not seem quite like other grown-ups. (theparisreview.org)