• To minimize the potential morbidity and mortality from drug-induced respiratory diseases, healthcare providers should be familiar with the possible adverse effects of the medications they prescribe. (medscape.com)
  • Before starting patients on any medication, educate them about the potential adverse effects of the drug. (medscape.com)
  • Radiologic patterns observed in drug-induced pulmonary toxicity are highly variable and depend on the type of adverse reaction the patient is experiencing. (medscape.com)
  • Chemotherapeutic agents interact with vitamin A in various ways, from adjunctive vitamin A for nutritive support and amelioration of adverse drug effects to cotherapy using retinoids as chemotherapeutic agents. (interactionsguide.com)
  • Patients who develop drug toxicity should be advised to avoid the drug in the future. (medscape.com)
  • Vivimusta (bendamustine hydrochloride injection) is an alkylating drug indicated for treatment of patients with chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. (rxlist.com)
  • Bronchoalveolar lavage (BAL) can contribute to the expected clinicopathologic pattern of a given drug-induced lung disease such as identifying eosinophils in a drug-induced eosinophilic pneumonia. (medscape.com)
  • Our Vivimusta (bendamustine hydrochloride injection), for Intravenous Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • In 1965, J.D. McColl and colleagues in Canada further illustrated the limitations of animal studies for the use of predicting human responses to potential teratogens. (asu.edu)
  • The authors noted that the study provided no grounds to think that drugs containing Thalidomide were safe for human use, and they argued that the only method guaranteed to safely deal with drugs of unknown teratogenicity would be to completely refrain from using them unless absolutely necessary. (asu.edu)
  • A 1962 study titled "Thalidomide and Congenital Abnormalities," by Victor Knapp, George Christie, and Mary Seller, all working in the UK, looked at the teratogenic effects of Thalidomide on rats, mice, and rabbits, and the study reported no abnormalities in the offspring of these animals after researchers had exposed the pregnant females to the drug. (asu.edu)
  • Liver dysfunction as evidenced by blood chemical abnormalities alone (liver enzyme elevations) has been observed in patients exposed to Dantrium for varying periods of time. (nih.gov)
  • Any liver injury caused by medication or herbal supplements that has led to biochemical abnormalities or liver dysfunction with the exclusion of other causes. (chestervetclinic.com)
  • Your health care provider will routinely test your blood to detect any abnormalities in liver enzymes or other damage to the organ, especially if you have hepatitis or any other underlying liver condition . (livestrong.com)
  • Higher-than-normal liver enzymes might be a sign of liver inflammation, a response to the extra work the organ does to metabolize chemo drugs while you're undergoing treatment. (livestrong.com)
  • Another concern during chemotherapy is that the drugs can cause damage to liver cells that leads to a rise in bilirubin, a red blood cell byproduct found in bile, according to an August 2016 article published in JAMA Oncology . (livestrong.com)
  • Does Transplantation Induce Aging In Patients? (medicaldaily.com)
  • We investigated CXXC5/RINF expression in primary human acute myeloid leukemia (AML) cells derived from 594 patients, and a wide variation in CXXC5/RINF mRNA levels was observed both in the immature leukemic myeloblasts and in immature acute lymphoblastic leukemia cells. (oncotarget.com)
  • Furthermore, patients with low-risk cytogenetic abnormalities showed significantly lower levels compared to patients with high-risk abnormalities, and high RINF/CXXC5/ mRNA levels were associated with decreased overall survival for patients receiving intensive chemotherapy for newly diagnosed AML. (oncotarget.com)
  • [ 5 ] Other therapies used outside of pregnancy, such as complementary and alternative therapies and biologic drugs ( e.g. , monoclonal antibodies), have unclear and/or mixed safety profiles during pregnancy and lactation. (medscape.com)
  • Abnormalities in the immune system may include the monoclonal proliferation of immunoglobulin producing cells. (vin.com)
  • [ 4 ] Similarly, nonsteroidal anti-inflammatory drugs (NSAIDs), commonly prescribed for treating migraine outside pregnancy, can potentially lead to spontaneous abortion (early in pregnancy) and fetal developmental malformations, such as premature closure of the ductus arteriosus and oligohydramnios (in the third trimester). (medscape.com)
  • Since some medications can cause different patterns of abnormalities, we look very closely at a patient's bloodwork throughout treatment,' Megan Kruse, MD , an oncologist at the Cleveland Clinic, tells LIVESTRONG.com. (livestrong.com)
  • This never occurs when drugs are involved. (vin.com)
  • Since Dantrium is probably metabolized by hepatic microsomal enzymes, enhancement of its metabolism by other drugs is possible. (nih.gov)
  • monitor clinically and discontinue drug for severe reactions. (drugs.com)
  • The absorption of Dantrium after oral administration in humans is incomplete and slow but consistent, and dose-related blood levels are obtained. (nih.gov)
  • In human animals this reaction is generally associated with specific blood groups and with specific drug-induced IHA. (vin.com)
  • Of the predicted and known human E3 ligase genes, we found ~13% were mutated in a neurological disorder with 83 total genes representing 70 different types of neurological diseases. (frontiersin.org)
  • Antibodies to red cells can arise as part of a normal immune response by a normal immune system or as a result of some abnormality of the control of the immune system. (vin.com)
  • Salistick detects pregnancy by identifying a hormone called human chorionic gonadotropin (hCG), which is present in the body of a pregnant person. (medicaldaily.com)
  • Symptomatic hepatitis (fatal and non-fatal) has been reported at various dose levels of the drug. (nih.gov)
  • Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
  • There is a threshold for how much abnormality should be taking place and, depending on how high the numbers go, we may take a short break, adjust medications or resume chemotherapy at a lower dose. (livestrong.com)
  • CXXC5/RINF knockdown in AML cell lines caused increased susceptibility to chemotherapy-induced apoptosis, and regulation of apoptosis also seemed to differ between primary human AML cells with high and low RINF expression. (oncotarget.com)