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  • Humans
  • EP2 expression in fibroblasts from the lungs of mice with Bleomycin-induced pulmonary fibrosis and humans with Idiopathic pulmonary fibrosis is greatly reduced. (wikipedia.org)
  • occur
  • citation needed] Non-vasculitis forms of panniculitis that may occur include: Cytophagic Histiocytic Panniculitis was first described in 1980 by Winkelmann as a chronic histiocytic disease of the subcutaneous adipose tissue, which is characterized clinically by tender erythematous nodules, recurrent high fever, malaise, jaundice, organomegaly, serosal effusions, pancytopenia, hepatic dysfunction and Coagulation abnormalities. (wikipedia.org)
  • Pregnancy
  • Most studies through 2013 linking development of the fetus and cannabis show effects of consumption during the gestational period, but abnormalities in the endocannabinoid system during the phase of placental development are also linked with problems in pregnancy. (wikipedia.org)
  • A report prepared for the Australian National Council on Drugs concluded cannabis and other cannabinoids are contraindicated in pregnancy as they may interact with the endocannabinoid system. (wikipedia.org)
  • Pregnant
  • CONCLUSIONS: Minimizing the risks of benzodiazepine therapy among pregnant or lactating women involves using drugs that have established safety records at the lowest dosage for the shortest possible duration, avoiding use during the first trimester, and avoiding multidrug regimens. (biomedsearch.com)
  • A woman in this situation may be unable to become pregnant, even with the help of drugs. (wikipedia.org)
  • Infectious
  • These conditions are listed below: Perinatal (during birth) cerebral injury Kernicterus Cerebrovascular diseases Drug induced Central nervous system tumor Peripheral or central trauma Infectious or post infectious encephalopathies Toxins Metabolic Paraneoplastic syndromes Central pontine myelinolysis Secondary spasmodic torticollis is diagnosed when any of the following are present: history of exogenous insult or exposure, neurological abnormalities other than dystonia, abnormalities on brain imaging, particularly in the basal ganglia. (wikipedia.org)
  • commonly
  • Pancreatic panniculitis (also known as "Enzymatic panniculitis," "Pancreatic fat necrosis," and "Subcutaneous fat necrosis") is a panniculitis most commonly associated with pancreatic carcinoma, and more rarely with anatomic pancreatic abnormalities, pseudocysts, or drug-induced pancreatitis. (wikipedia.org)
  • Although a few cytostatics may cause these changes, the drugs most commonly involved are adriamycin, cyclophosphamide and vincristine, or in polychemotherapy Also chromonychia is associated with AIDS. (wikipedia.org)
  • effects
  • The effects of green tea extract (GTE) on the fetal development and external, visceral and skeletal abnormalities induced by cyclophosphamide were investigated in rats. (biomedsearch.com)
  • Did you experience many side effects while taking this drug? (rxwiki.com)
  • Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers. (wikipedia.org)
  • Patients
  • Neutropenia itself is a rare entity, but can be clinically common in oncology and immunocompromised patients as a result of chemotherapy (drug-induced neutropenia). (wikipedia.org)
  • CIRCI can be suspected in patients with low blood pressure despite resuscitation with intravenous fluids and vasopressor drugs. (wikipedia.org)
  • In some patients a specific reason for adrenal insufficiency can be suspected, such as prior intake of corticosteroids that suppressed the HPA axis, or use of enzyme inducing drugs such as phenytoin. (wikipedia.org)
  • Other stimulation tests for adrenal insufficiency which are used in non-critical patients, such as the test using metyrapone or a test which employs insulin to induce hypoglycemia, are not preferred for CIRCI. (wikipedia.org)
  • Both a metyrapone-induced decrease in cortisol and hypoglycemia are potentially harmful to intensive care patients. (wikipedia.org)
  • brain
  • The non-selective melanocortin receptor agonist afamelanotide (NDP-α-MSH) has been found to induce brain-derived neurotrophic factor (BDNF) expression in the rodent brain via activation of the MC4 receptor and mediate "intense" neurogenesis and cognitive recovery in an animal model of Alzheimer's disease. (wikipedia.org)
  • found
  • A significant number of drugs found within this class, including moxifloxacin, are not licensed by the FDA for use in children due to the risk of permanent injury to the musculoskeletal system. (wikipedia.org)
  • Only two listed contraindications are found within the 2008 package insert: "Nonsteroidal anti-inflammatory drugs (NSAIDs): Although not observed with moxifloxacin in preclinical and clinical trials, the concomitant administration of a nonsteroidal anti-inflammatory drug with a fluoroquinolone may increase the risks of CNS stimulation and convulsions. (wikipedia.org)
  • intravenous
  • The best known feature that suggests a possible underlying adrenal insufficiency is low blood pressure despite resuscitation with intravenous fluids, requiring vasopressor drugs. (wikipedia.org)
  • treatment
  • Treatment with imidazole drugs such as etomidate, ketoconazole and miconazole can also suppress the HPA axis, as well as drugs used specifically for this purpose, such as metyrapone. (wikipedia.org)
  • suggest
  • The results suggest that repeated intake of GTE may aggravate cyclophosphamide-induced body weight loss and malformations of fetuses by modulating CYP2B and CYP3A. (biomedsearch.com)
  • individual
  • The rate of spontaneous mutations that confer resistance to an individual drug are well known: 1 mutation for every 107 cell divisions for EMB, 1 for every 108 divisions for STM and INH, and 1 for every 1010 divisions for RMP. (wikipedia.org)
  • either
  • These drugs are listed here either because they are not very effective (e.g., clarithromycin) or because their efficacy has not been proven (e.g., linezolid, R207910). (wikipedia.org)
  • types
  • That is, following agonist-induced activation, the other prostaglandin (as well as most types of G protein coupled receptors) quickly become desensitized, often internalized, and whether or not internalized, incapable of activating their G protein targets. (wikipedia.org)
  • administration
  • An IV tube is generally inserted to keep the patient hydrated and to allow for the administration of sedatives, anesthesia, or drugs. (wikipedia.org)
  • blood vessels
  • Tumors induce the proliferative vascular response of host blood vessels by influencing the local balance of angiogenic regulators, a rate-limiting step termed the angiogenic switch [ 9 , 10 ]. (hindawi.com)
  • depression
  • MI or ischemia (either ST elevation or depression) may be mimicked either by 1) repolarization abnormalities (As in Case 2, with ST elevation) or by 2) confusing the J-wave with the ST segment, as in this case in JACC (full text) and this case in Archives of Internal Medicine (no full text) . (blogspot.ca)
  • This latter case also has ST segment depression as a repolarization abnormality. (blogspot.ca)
  • Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death [see WARNINGS , DRUG INTERACTIONS ]. (rxlist.com)
  • rarely
  • Macropsia has a wide range of causes, from prescription and illicit drugs, to migraines and (rarely) complex partial epilepsy, and to different retinal conditions, such as epiretinal membrane. (wikipedia.org)
  • calcium
  • Due to its hydrophilic character, IP3 can travel to the endoplasmic reticulum, where it induces, via fixation on its receptor, the opening of calcium channels increasing in this way the cytosolic calcium concentrations. (wikipedia.org)
  • Among
  • Among its related pathways are Regulation of retinoblastoma protein and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers . (genecards.org)
  • Foremost among these abnormalities is the fact that the neurons are usually harvested as neural stem cells from a fetus and are therefore disrupted at a critical stage in network development. (wikipedia.org)
  • food
  • This drug/food mixture should be swallowed immediately without chewing and followed with a glass of water to ensure complete swallowing of the pellets (spheroids). (rxlist.com)
  • group
  • LY-341,495 and MGS-0039 are drugs that act as a selective antagonist blocking both of the group II metabotropic glutamate receptors, mGluR2 and mGluR3. (wikipedia.org)
  • Earlier, a group at Bayer, a drug company, successfully repeated only one fourth of 67 important papers. (wikipedia.org)
  • suggest
  • These findings suggest that DR promoted vessel normalization by preventing VEGF-induced inhibition of the PDGF signaling axis in pericytes. (hindawi.com)