• There is an increased risk of myelodysplasia and myeloid leukemia. (medscape.com)
  • Acute Myeloid Leu. (hematology.org)
  • 3. Prognostic factors and treatment effects on survival in acute myeloid leukemia of M6 subtype: a retrospective study of 54 cases. (nih.gov)
  • 4. Characteristics of acute myeloid leukemia with myelodysplasia-related changes: A retrospective analysis in a cohort of Chinese patients. (nih.gov)
  • 6. Acute myeloid leukemia or myelodysplastic syndrome with chromosome 17 abnormalities and long-term outcomes with or without hematopoietic stem cell transplantation. (nih.gov)
  • 10. Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype. (nih.gov)
  • 11. Epigenetic priming with decitabine followed by low dose idarubicin and cytarabine in acute myeloid leukemia evolving from myelodysplastic syndromes and higher-risk myelodysplastic syndromes: a prospective multicenter single-arm trial. (nih.gov)
  • 12. Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prognostic relevance: a comparison of 408 cases classified as "AML not otherwise specified" (AML-NOS) or "AML with myelodysplasia-related changes" (AML-MRC). (nih.gov)
  • Leukemia Basophilic A rare acute myeloid leukemia in which the immature cells differentiate towards basophils. (nih.gov)
  • Malignant C6923 Acute Bilineal Leukemia An acute leukemia of ambiguous lineage in which there is a dual population of blasts with each population expressing markers of a distinct lineage (myeloid and lymphoid or B-and T-lymphocyte). (nih.gov)
  • WHO, 2001) Malignant C4673 Acute Biphenotypic Leukemia An acute leukemia of ambiguous lineage characterized by blasts which coexpress myeloid and T or B lineage antigens or concurrent B and T lineage antigens. (nih.gov)
  • M6 Acute Myeloid Leukemia An acute myeloid leukemia characterized by a predominant immature erythroid population. (nih.gov)
  • WHO, 2001) Malignant C7464 Acute Leukemia of Ambiguous Lineage Acute Leukemia of Indeterminate Lineage An acute leukemia in which the blasts lack sufficient evidence to classify as myeloid or lymphoid or they have morphologic and/or immunophenotypic characteristics of both myeloid and lymphoid cells. (nih.gov)
  • FAB M7 An acute myeloid leukemia in which at least 50% of the blasts are of megakaryocytic lineage. (nih.gov)
  • VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is caused by UBA1 somatic mutations and is characterized by late-onset systemic autoimmune inflammation and blood abnormalities such as cytopenia, vacuolation of myeloid/erythroblastic cells, and myelodysplastic syndrome (MDS). (bvsalud.org)
  • Workup for erythroleukemia includes blood studies, bone marrow aspiration and biopsy (the definitive diagnostic tests), analysis of genetic abnormalities, and diagnostic imaging. (medscape.com)
  • Vitamin B12 and folate - Severe pernicious anemia sometimes mimics acute erythroleukemia. (medscape.com)
  • Bone marrow aspiration and biopsy are critical in making the diagnosis of acute erythroleukemia. (medscape.com)
  • Erythroleukemia is required to have both erythroblastic and myeloblastic components (see the image below). (medscape.com)
  • The assessment of chromosomal abnormalities in patients with erythroleukemia is critical in the diagnosis and prognosis of disease. (medscape.com)
  • 1. Adult acute erythroleukemia: an analysis of 91 patients treated at a single institution. (nih.gov)
  • 9. [Analysis of clinical characteristics and prognosis of 13 cases of acute erythroleukemia]. (nih.gov)
  • 14. Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study. (nih.gov)
  • 15. The erythroid leukemias: a comparative study of erythroleukemia (FAB M6) and Di Guglielmo disease. (nih.gov)
  • There are two subtypes recognized: erythroleukemia and pure erythroid leukemia. (nih.gov)
  • Precursor Lymphoblastic Leukemia Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. (nih.gov)
  • It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia. (nih.gov)
  • Acute Lymphoblastic Leukemia by Gene Expression Signature Gene expression-based patient cluster groups in acute lymphoblastic leukemia. (nih.gov)
  • Acute Lymphoblastic Leukemia ROSE Cluster Unique gene expression-based patient cluster groups in high-risk B-precursor acute lymphoblastic leukemia determined by Recognition of Outliers by Sampling Ends (ROSE). (nih.gov)
  • 5. An analysis of 97 previously diagnosed de novo adult acute erythroid leukemia patients following the 2016 revision to World Health Organization classification. (nih.gov)
  • Any cancer/malignancy (either a "solid tumor" or a leukemia/lymphoma/bone marrow malignancy/"liquid tumor", i.e. any ICD10 code from C00-C99) can be a comorbid diagnosis --- BUT it's vital to distinguish malignancies in this category based on whether they are believed to be cured or not. (kuality.ca)
  • Allogeneic hematopoietic stem cell transplantation is curative but it requires a histocompatible donor and is associated with significant morbidity and mortality, so it is reserved for severe cases of PNH with aplastic anemia or transformation to leukemia. (medscape.com)
  • Leukemia, a malignant transformation of hematopoietic cells, is one of the most prevalent types of cancer, especially in children and, globally, it was ranked 10th for cancer incidence and nineth for cancer deaths. (japsonline.com)
  • Leukemia is a malignant transformation of hematopoietic cells which produces an abnormal leukemic clone of cells suppressing the production of normal blood cellular components ( Duhrsen and Hossfeld, 1996 ). (japsonline.com)
  • Myelofibrosis may be observed prior to a clear diagnosis of acute leukemia[3] at the time of diagnosis of leukemia,[4] or as a late event in patients previously treated for leukemia. (medscape.com)
  • 13. Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia. (nih.gov)
  • With anemia due to acute blood loss, a reduction in oxygen-carrying capacity occurs along with a decrease in intravascular volume, with resultant hypoxia and hypovolemia. (medscape.com)
  • Multiple chromosomal abnormalities have been described, but none of them is specific for M6 acute myelogenous leukemia (AML). (medscape.com)
  • Our results indicate that NBPQD is able to alleviate leukemia and it is worthy of further characterization as a potential anti-leukemic drug. (japsonline.com)
  • Causes of leukemia are diverse and they could be familial, infectious, physical, or chemical depending on the cell type and the individual variations from one patient to another ( Pui, 1995 ). (japsonline.com)