• Profile of international air passengers in- pathogenic Escherichia coli (ExPEC) nIII MicroPlate (Biolog, Hayward, tercepted with illegal animal products in have globally expanded their distribu- CA, USA). (cdc.gov)
  • CDC is monitoring a large outbreak of Shiga toxin-producing Escherichia coli O104:H4 (STEC O104:H4) infections ongoing in Germany. (cdc.gov)
  • Antibodies towards several O antigens cross-react with other O antigens and partially to K antigens not only from E. coli, but also from other Escherichia species and Enterobacteriaceae species. (wikipedia.org)
  • Chronic bacterial prostatitis (CBP) is most often caused by Escherichia coli or other gram-negative Enterobacteriaceae, and typically affects men 36 to 50 years of age. (medscape.com)
  • Shiga toxin (Stx) is the main virulence factor of Shiga toxin-producing Escherichia coli (STEC), and ruminants are the main reservoir of STEC. (frontiersin.org)
  • During the same period, almost half of Escherichia coli isolates developed resistance to cefotoxime. (who.int)
  • The Enteroaggregative Escherichia coli (EAggEc) are a complex group of bacterial organisms which have a distinctive phenotype and a strong association with persistent diarrheal disease in children in the developing world and in patients infected with the Human Immunodeficiency Virus (HIV). (usda.gov)
  • Not all patients colonized with Enteroaggregative Escherichia coli are symptomatic. (usda.gov)
  • Let's consider this idea with a simplified example using a strain of Escherichia coli that is nonfermenting. (emory.edu)
  • Escherichia coli , a member of the family Enterobacteriaceae, is a lactose fermenter, causing a distinct color on diagnostic agar. (vin.com)
  • Escherichia coli rapidly develops resistance, particularly that associated with multiple drug resistance (MDR) when exposed to selected antimicrobials. (vin.com)
  • Alfredo G. Torres , " Pathogenic Escherichia coli in Latin America ", Bentham Science Publishers (2010). (eurekaselect.com)
  • Escherichia coli are Gram-negative bacteria found as normal commensal flora in the gastrointestinal tract. (eurekaselect.com)
  • The emergence and evolution of pathogenic Escherichia coli strains associated with diarrheal diseases have become a topic of active investigation in recent years due to the emergence of more virulent strains and the association of new serotypes with disease. (eurekaselect.com)
  • The α-haemolysin (HlyA) of Escherichia coli is the prototype RTX (repeat in toxin) toxin and is thought to be important in virulence because of its ability to lyse cells by formation of pores in the cell membrane. (microbiologyresearch.org)
  • The different hemolysins of Escherichia coli. (microbiologyresearch.org)
  • Effects of Escherichia coli hemolysin in human monocytes. (microbiologyresearch.org)
  • Distribution and characterization of fecal verotoxin-producing Escherichia coli (VTEC) isolated from healthy cattle. (microbiologyresearch.org)
  • Calcium is required for binding of Escherichia coli hemolysin (HlyA) to erythrocyte membranes. (microbiologyresearch.org)
  • Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections. (microbiologyresearch.org)
  • Effect of Escherichia coli β- hemolysin on human peripheral leukocyte viability in vitro. (microbiologyresearch.org)
  • We therefore determined if the IBD-associated adherent-invasive Escherichia coli (AIEC) can modulate the UPS functioning. (bmj.com)
  • Escherichia coli and Staphylococcus aureus are important causes of severe diseases like blood stream infections. (scienceopen.com)
  • Among the common uropathogens associated to UTIs development, UroPathogenic Escherichia coli (UPEC) is the primary cause. (scienceopen.com)
  • Antimicrobial resistant strains of Escherichia coli ( E. coli ) are a common cause of UTI which were identified as a treatment challenge. (biomedcentral.com)
  • 7 Other pathogens include adenovirus, Escherichia coli , herpes simplex, Mycoplasma , and Trichomonas (Bradshaw urethritis). (uspharmacist.com)
  • This study aimed to evaluate the antibiotic resistance patterns, virulence factors, biofilm-forming strength, and genetic linkage of Escherichia coli strains isolated from bloodstream infections (BSIs) of leukemia patients. (biomedcentral.com)
  • Extraenteropathogenic Escherichia coli (ExPEC) are an isolates that can enter the bloodstream and survive and invade the host [ 13 ]. (biomedcentral.com)
  • Sandrine Adiba from Pierre and Marie Curie University found evidence to support it by showing that the typically harmless gut bacterium Escherichia coli can cause disease in mice after it's exposed to the threat of amoebas. (nationalgeographic.com)
  • Enterotoxins, generated by some bacteria (ie, enterotoxigenic Escherichia coli, Vibrio cholera ) act directly on secretory mechanisms and produce a typical, copious watery (rice water) diarrhea. (medscape.com)
  • Diarrheagenic Escherichia coli ( E. coli ) species are a diverse group of pathogens classified into 5 major pathotypes that can cause intestinal infection and diarrhea. (lecturio.com)
  • Escherichia coli Escherichia coli The gram-negative bacterium Escherichia coli is a key component of the human gut microbiota. (lecturio.com)
  • Under an extremely high magnification of 44, 818X, twice that of PHIL 10574 and 10575, this scanning electron microscopic (SEM) image revealed some of the morphologic details displayed by a single Gram-negative, rod-shaped, Escherichia coli bacterium. (lecturio.com)
  • They include shiga toxin which is produced by Shigella dysenteriae and a variety of shiga-like toxins that are produced by pathologic strains of Escherichia coli such as Escherichia coli o157. (lecturio.com)
  • To evaluate antibacterial behavior, we used two bacterial strains Gram-negative Escherichia coli ( E. coli ) and Gram-positive Staphylococcus aureus ( S. aureus ). (nature.com)
  • Experimental vaccination with nanoparticles containing Escherichia coli virulence factors 2. (researchandmarkets.com)
  • Recombinant expression of proteins of interest in Escherichia coli is an important tool in the determination of protein structure. (iucr.org)
  • An impediment to the successful production of large quantities of natively folded proteins in Escherichia coli is the tendency of many proteins to become insoluble when overexpressed. (iucr.org)
  • Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune Cell Populations Following Broad-spectrum Antibiotic Treatment. (uni-kiel.de)
  • Aim of this study was to examine the ability of defined Gram-positive and Gram-negative intestinal commensal bacterial species, namely Escherichia coli and Lactobacillus johnsonii, respectively, to restore immune functions in mice that were immunosuppressed by antibiotics-induced microbiota depletion. (uni-kiel.de)
  • For example, Escherichia coli - and likewise its Sal-mo-nel-la cousins - lacks a homolog of the Vibrio fischeri LuxI synthetase for the common au-to-in-du-cer in Gram-negative bacteria, N-acyl homoserine lactone ( AHL ). (asmblog.org)
  • Enteroaggregative Escherichia coli (EAEC or EAggEC) is a pathotype of Escherichia coli that is responsible for both acute and chronic diarrhea in both developed and developing countries. (microbiologynote.com)
  • In recent years, EAEC has received increasing attention as an emerging enteric pathogen, highlighting the need for further research and understanding of this pathotype of Escherichia coli. (microbiologynote.com)
  • Disease caused by Enteroaggregative Escherichia coli (EAEC) can have significant impacts, particularly in children. (microbiologynote.com)
  • A Novel Locally c-di-GMP-Controlled Exopolysaccharide Synthase Required for Bacteriophage N4 Infection of Escherichia coli . (hu-berlin.de)
  • Kettles, R., N. Tschowri, K. Lyons, P. Sharma, R. Hengge, M. Webber, and D. Grainger (2019) The Escherichia coli MarA protein regulates the ycgZ-ymgABC operon to inhibit biofilm formation. (hu-berlin.de)
  • Serra, D.O. and Regine Hengge (2019) A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms. (hu-berlin.de)
  • Shiga Toxin producing Escherichia coli (STEC) are potentially highly virulent and can cause illness at levels of 10 cells if ingested by a susceptible host. (centerforproducesafety.org)
  • There has been an increase in the number of outbreaks linked to fresh produce contaminated with Shiga Toxin producing Escherichia coli (STEC). (centerforproducesafety.org)
  • We aim to use the Mesolens to image the previously unexplored internal architecture of an intact Escherichia coli colony biofilm to better understand spatiotemporal organisation of a live acterial community. (hw.ac.uk)
  • The newly discovered extracellular death factor (EDF) is a pentapeptide with the sequence NNWNN in Escherichia coli . (springeropen.com)
  • In the present study, our results indicated that tryptophan could be the key residue to the hydroxyl radicals-scavenging activity of EDF, and EDF could protect Escherichia coli from killing by bactericidal antibiotics, but not by DNA-damaging or bacteriostatic antibiotics. (springeropen.com)
  • A genomically recoded Escherichia coli strain that lacks all amber codons and release factor 1 (C321. (northwestern.edu)
  • A study by Shaikh et al indicates that in children and adolescents with a first UTI, the risk of scarring is doubled in those with either an abnormal renal ultrasonographic finding or with both a fever of 39°C (102°F) or above and a causative organism other than Escherichia coli. (medscape.com)
  • We did this for illnesses caused by Campylobacter , Escherichia coli O157, or E. coli O157, Listeria , and Salmonella bacteria. (cdc.gov)
  • To achieve enzyme-activatable cMOs, we focused on the Escherichia coli nitroreductase NfsB as the triggering catalyst. (cdc.gov)
  • Escherichia coli, Klebsiella pneumoniae, Shigella, testing (AST) patterns is the cornerstone of an effective a School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia. (who.int)
  • Most E. coli strains are harmless, but pathogenic varieties cause serious food poisoning, septic shock, meningitis, or urinary tract infections in humans. (wikipedia.org)
  • E. coli and related bacteria constitute about 0.1% of gut flora, and fecal-oral transmission is the major route through which pathogenic strains of the bacterium cause disease. (wikipedia.org)
  • Pathogenic E. coli strains can be categorized based on elements that can elicit an immune response in animals, namely:[citation needed] O antigen: part of lipopolysaccharide layer K antigen: capsule H antigen: flagellin For example, E. coli strain EDL933 is of the O157:H7 group. (wikipedia.org)
  • In humans and in domestic animals, virulent strains of E. coli can cause various diseases. (wikipedia.org)
  • None of the other work that has been done to date on serogroups of EAggEc strains, entero or cytotoxins, invasive ability, clump formation or hemagglutinins can explain the pathogenesis of diarrhea associated with these organisms or serve as a definitive means of identifying clinically important EAggEc strains as these factors have not been identified in the majority of EAggEc strains from various geographic locations. (usda.gov)
  • To pursue this question, the researchers studied 21 representative E. coli strains obtained from the urine of 14 women who suffered from recurrent UTIs. (nih.gov)
  • Using the first mouse model, they found that variation in the activity of certain genes regulating core E. coli functions correlated with how effectively the strains infected the animals. (nih.gov)
  • Together, the study findings suggest that rather than a signature set of genes consistently determining virulence, a more complex and dynamic interplay between E. coli strains and their host environment determines infection and subsequent disease. (nih.gov)
  • Due to the appearance of the highly virulent strain of E. coli of serotype O157:H7 in the US and Canada in the 1980's, and subsequently in other Latin American countries, there is an increase need for accurate testing for this and other pathogenic E. coli strains, substantially enhancing detection of virulent strains and, therefore, facilitating identification of sporadic E. coli infections and outbreaks. (eurekaselect.com)
  • The relative contribution of recombination events in the generation of new categories of pathogenic E. coli varies among the E. coli population, and it is represented by the wide variety of mobile elements found in different diarrheal strains (e.g. pathogenicity islands, phages, transposons, pathoadaptive mutations, etc). (eurekaselect.com)
  • In addition, factors underlying the emergence of enteroaggregative and atypical enteropathogenic E. coli strains associated with persistent diarrhea are unknown. (eurekaselect.com)
  • Horizontal transfer of genetic elements that affect virulence of diarrheagenic E. coli strains and changes in global agricultural processes, as well as movement of humans and animals, may contribute to the complex natural history of diarrheagenic E. coli. (eurekaselect.com)
  • UPEC strains possess a plethora of both structural (as fimbriae, pili, curli, flagella) and secreted (toxins, iron-acquisition systems) virulence factors that contribute to their capacity to cause disease, although the ability to adhere to host epithelial cells in the urinary tract represents the most important determinant of pathogenicity. (scienceopen.com)
  • The study conducted in Iran from June 2021 to December 2022, isolated 67 E. coli strains from leukemia patients' bloodstream infections in hospitals in two different areas. (biomedcentral.com)
  • Several techniques including disk diffusion and broth microdilution were used to identify patterns of antibiotic resistance, microtiter plate assay to measure biofilm formation, and PCR to evaluate the prevalence of different genes such as virulence factors, toxin-antitoxin systems, resistance to β-lactams and fluoroquinolone antibiotics of E. coli strains. (biomedcentral.com)
  • ExPEC strains contain numerous virulence factors (VFs) that allow bacterial cells to colonize. (biomedcentral.com)
  • These may contribute to the ability of C. coli OR12 to out-compete other Campylobacter strains, and to resist environmental stresses. (nottingham.ac.uk)
  • E.coli is mostly harmless, but some strains can cause severe food poisoning. (nationalgeographic.com)
  • Adiba found that one such predator - an amoeba called Dictyostelium discoideum - was very good at munching its way through harmless strains of E.coli , but a disease-causing strain known as 536 was too much to swallow. (nationalgeographic.com)
  • Adiba confirmed that by pitting 31 different strains of E.coli against Dictyostelium . (nationalgeographic.com)
  • Some E.coli strains wield poisons called Shiga toxins that are bad news for their hosts, but that also ward off a predator called Tetrahymena . (nationalgeographic.com)
  • Most strains of E. coli are avirulent, but occasionally they escape the GI tract, infecting the urinary tract and other sites. (lecturio.com)
  • Less common strains of E. coli are able to cause disease within the GI tract, most commonly presenting as abdominal pain and diarrhea. (lecturio.com)
  • Diarrheagenic strains of E. coli can be classified into 5 key "pathotypes," each of which has unique virulence factors Virulence factors Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. (lecturio.com)
  • The Ti-Cu films displayed superior antibacterial ability, with a 99.9% reduction (equivalent to a 5-log reduction) in bacterial viability after 2 h compared to Ti alone against both bacterial strains. (nature.com)
  • SdiA has been shown to be involved in the re-gu-la-tion of acid resistance, of flagellar genes, and of virulence factors in EHEC strains ( Shiga toxin ), but it is not yet entirely clear to what extent regulation by SdiA depends on AHL binding. (asmblog.org)
  • EAEC strains exhibit genetic heterogeneity, and identifying virulence factors important for pathogenesis has proven challenging. (microbiologynote.com)
  • Many EAEC strains encode a transcriptional factor called aggR (aggregative regulator), which belongs to the AraC family of transcription activators. (microbiologynote.com)
  • They are characterized as E. coli strains that do not secrete enterotoxins LT or ST and adhere to HEp-2 cells in an AA pattern. (microbiologynote.com)
  • Further research has also found that certain STEC strains have the ability to acquire or lose virulence factors. (centerforproducesafety.org)
  • Unlike normal flora E. coli, the pathogenic varieties produce toxins and other virulence factors that enable them to reside in parts of the body normally not inhabited by E. coli, and to damage host cells. (wikipedia.org)
  • Virulence factors are encoded on bacterial chromosomes, usually located within pathogenicity islands (PAIs), or on plasmids [ 14 ]. (biomedcentral.com)
  • These genes help to foil predators, but they're also "virulence factors" that allow E.coli to successfully infect mammal cells. (nationalgeographic.com)
  • Virulence factors Virulence factors Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. (lecturio.com)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • AggR regulates various plasmid and chromosomally encoded virulence factors, including those involved in aggregative adherence fimbriae biogenesis and toxin production. (microbiologynote.com)
  • Injection of Virulence Factors Through the Cell Membrane: Several pathogenic bacteria including Yersina ssp. (umass.edu)
  • ent in 7.1% of the E. coli isolates from Author affliliations: University of Brasília, Development and validation of a triplex urinary tract infections ( 3 ). (cdc.gov)
  • This issue will be addressed by undertaking molecular characterization of EAggEc isolates from patients in whom 'host factors' which may be related to EAggEc pathogenesis can be measured. (usda.gov)
  • However, a significant risk exists that infections caused by highly virulent E. coli isolates, such as the enterohemorrhagic E. coli O157:H7, develop into serious and potentially lifethreatening complications, such as hemolytic uremic syndrome. (eurekaselect.com)
  • These factors were evaluated in various phylogenetic groups (phylotypes) of E. coli isolates. (biomedcentral.com)
  • The ability of extended spectrum β-lactamases (ESBLs) production in E. coli isolates was detected using the combined disc diffusion method. (biomedcentral.com)
  • This study's results confirmed an explosion of antibiotic resistance amongst E. coli isolates from UTI against β-lactams and fluoroquinolones. (biomedcentral.com)
  • More than 80% of the isolates showed the ability to form biofilms. (biomedcentral.com)
  • The genetic diversity was detected in E. coli isolates. (biomedcentral.com)
  • Some bacteria , such as E. coli , have several flagella per cell (4-10 typically). (wikidoc.org)
  • Bacteria such as E. coli are unable to choose the direction in which they swim, and are unable to swim in a straight line for more than a few seconds due to rotational diffusion . (wikidoc.org)
  • In other words, bacteria like E. coli use temporal sensing to decide whether life is getting better or worse. (wikidoc.org)
  • Factors that predispose the elderly to bacteriuria include hormonal changes, such as estrogen deficiency resulting in vaginal atrophy, or a reduction in colonizing lactobacilli causing an increase in vaginal pH, leading to subsequent colonization with pathogenic bacteria. (uspharmacist.com)
  • Some scientists have suggested that for many bacteria , the ability to resist grazing amoebas came before the ability to cause disease in humans and other mammals. (nationalgeographic.com)
  • Cytotoxin production by other bacteria (ie, Shigella dysenteriae, Vibrio parahaemolyticus, Clostridium difficile, enterohemorrhagic E coli ) results in mucosal cell destruction that leads to bloody stools with inflammatory cells. (medscape.com)
  • Genome engineering tools in bacteria are limited by their targeting abilities, cargo size capacities, and integration efficiencies. (biorxiv.org)
  • Biofilms pose a public health risk due to their ability to protect bacteria from mechanical, environmental and chemical factors. (hw.ac.uk)
  • Periplasmic stress, also known as envelope stress, is triggered by several factors that influence the ability of the bacteria to communicate with other cells through quorum sensing, pathological pathway, pili formation, outer membrane protein formation which plays a role in adhesion of the cells allowing them to form proper colonies and survive. (igem.org)
  • Besides the vegetative sigma factor, which recognizes the "standard" promoter, many bacteria possess alternative sigma factors that confer altered promoter specificity upon RNAP [ 2 ]. (hindawi.com)
  • Contamination of stream and tank water with en- of resistant pathogens should inform standard treatment teric bacteria, including Salmonella Typhi, is documented guidelines that are developed in the Pacific region. (who.int)
  • Both E. coli O157:H7 and non-O157:H7 serotypes can cause human disease and among non-O157 infections, up to 70% of human infections are attributed to six non-O157 STEC serogroups (O26, O45, O103, O111, O121, and O145) ( Bosilevac and Koohmaraie, 2012 ). (frontiersin.org)
  • Multiplex PCR (polymerase chain reaction) assay for detection of E. coli O157:H7, Salmonella sp. (ac.bd)
  • Antibiotics are reserved for severe or persistent infections and are contraindicated with enterohemorrhagic E. coli because of the risk of hemolytic uremic syndrome. (lecturio.com)
  • La sensibilité de Staphylococcus aureus à l'oxacilline a diminué significativement, passant de 95,0 % entre 1999 et 2002 à 84,4 % en 2008. (who.int)
  • 11 Bacteriology studies in prostatitis commonly implicate E coli , Proteus , Klebsiella , Streptococcus , Staphylococcus aureus , and Enterococcus . (uspharmacist.com)
  • Staphylococcus epidermidis était l'isolat le plus fréquent en 2001, suivi de Pseudomonas aeruginosa, alors qu'en 2002, les colibacilles étaient les plus répandus, suivis de P. aeruginosa. (who.int)
  • commonly abbreviated E. coli) is a gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms (endotherms). (wikipedia.org)
  • As of July 5, 2011, case counts confirmed by Germany's Robert Koch Institute include 852 patients with hemolytic uremic syndrome (HUS)-a type of kidney failure that is associated with Shiga toxin-producing E. coli, or STEC, infections-and 32 HUS-associated deaths. (cdc.gov)
  • The responsible strain shares virulence characteristics with enteroaggregative E. coli (EAEC). (cdc.gov)
  • The ability of organisms to develop resistance to an antimicrobial varies with the species and strain. (vin.com)
  • By comparing this score with how well each strain infected bladders in a standard female mouse model, the researchers determined that having a higher PUF gene score did not correlate with either strength (robust, variable, or deficient) of an acute infection, or with the ability to cause chronic infection in one mouse model. (nih.gov)
  • The outbreak was caused by an EAEC O104:H4 strain that was infected with a Shiga toxin-encoding phage, typically associated with Shiga toxin-producing E. coli. (microbiologynote.com)
  • Wild type E. coli MC4100 strain was obtained from China General Microbiological Culture Collection Center (CGMCC) (Number: 1.156). (springeropen.com)
  • Using an optimized platform, the ability to introduce two identical N 6 -(propargyloxycarbonyl)- L -Lysine residues site specifically into sfGFP with a 17-fold improvement in production relative to the parent strain is demonstrated. (northwestern.edu)
  • However, this does not mean that the organisms themselves have the abilities to influence which mutations may or may not arise. (emory.edu)
  • Among the most adaptable organisms is E. coli . (vin.com)
  • In human medicine, E. coli has developed resistance to the fluorinated quinolones, beta-lactams, or both: it is among the gram-negative organisms that secrete extended-spectrum beta-lactamases (ESBL). (vin.com)
  • The primary causative organisms, Campylobacter jejuni and C. coli, colonize the chicken's gastrointestinal tract and contaminated poultry meat is the primary mode of transmission to humans. (nottingham.ac.uk)
  • Enterocyte invasion is the preferred method by which microbes such as Shigella and Campylobacter organisms and enteroinvasive E coli cause destruction and inflammatory diarrhea. (medscape.com)
  • Goals and Objectives Goal I Detect, promptly investigate, and monitor emerging pathogens, the diseases they cause, and the factors influencing their emergence. (cdc.gov)
  • Outbreak studies indicate that most patients with an intestinal E. coli infection develop mild, uncomplicated diarrhea. (eurekaselect.com)
  • Superficial infection with E. coli was associated with a reduced duration of hospital stay by −2.46 days and a reduced odds ratio of infectious diseases as main diagnosis of 0.04. (scienceopen.com)
  • Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St. (medscimonit.com)
  • Specific risk factors for mortality include sepsis, urinary tract infection, nutritional oedema and hypokalaemia. (bvsalud.org)
  • enterophatogenic E. coli, Pseudomonas aeruginosa, Shigella flexneri, etc., inject proteins directly into the eukaryotic cell cytoplasm to interfere with and to alter host processes. (umass.edu)
  • Such studies are needed to understand the increasingly recognized diversity of enterotoxigenic E. coli, a leading cause of pediatric and travelers' diarrhea. (eurekaselect.com)
  • EAEC is considered an emerging enteric pathogen, and it is the second most common cause of traveler's diarrhea, following Enterotoxigenic E. coli. (microbiologynote.com)
  • On June 24, 2011, France reported a cluster of E. coli O104:H4 infections among persons who attended an event in Bordeaux, France. (cdc.gov)
  • As a pathogen, E. coli are the most frequent causes of bacterial infections, including urinary tract infections, diarrheal disease, and other clinical infections such as neonatal meningitis, pneumonia and bacteremia. (eurekaselect.com)
  • At least six different categories of pathogenic E. coli causing enteric infections have been identified and further characterized. (eurekaselect.com)
  • In Latin America, as well as many other developing countries, diarrheal infections caused by E. coli remain an important cause de infant morbidity - mortality. (eurekaselect.com)
  • These results indicate that extracellular actin enhances haemolysin production by E. coli and may have implications in the pathogenesis of E. coli infections. (microbiologyresearch.org)
  • Conclusions: Reduced disease severity of superficial infections due to both E. coli and S. aureus and resistance-driven prolonged stays in hospital were confirmed, while other outcome parameters were comparable. (scienceopen.com)
  • More attention should be paid to the treatment and management of E. coli bloodstream infections in patients with leukemia. (biomedcentral.com)
  • This thesis examined factors influencing Campylobacter colonization of the chicken's gastrointestinal tract and several potential interventions to reduce this. (nottingham.ac.uk)
  • Campylobacter coli OR12 grows on aerobically incubated blood agar. (nottingham.ac.uk)
  • Collectively these findings further our knowledge of factors which may influence Campylobacter colonization of chickens and provide novel avenues for investigation. (nottingham.ac.uk)
  • Although Campylobacter are generally cultured under microaerophilic atmospheres, recent findings have indicated that this pathogen can be cultured aerobically in media containing appropriate growth factors. (usda.gov)
  • Purpose: In this study, media supplemented with various concentrations of beef extract were examined for the ability to support aerobic growth of Campylobacter. (usda.gov)
  • Characterization of dendritic cells generated in vivo by an E. coli derived chimeric dual receptor agonist. (medscimonit.com)
  • Midha, A., K. Janek, A. Niewienda, P. Henklein, S. Guenther, D.O. Serra, J. Schlosser, R. Hengge, and S. Hartmann (2018) The intestinal roundworm Ascaris suum releases antimicrobial factors which interfere with bacterial growth and biofilm formation. (hu-berlin.de)
  • This study assessed the abundance and expression of Stx genes and the expression of host immune genes, aiming to determine factors affecting these measures and potential gene markers to differentiate Stx gene expression in the recto-anal junction of feedlot beef cattle. (frontiersin.org)
  • These environmental factors induce selective pressures on the organism genes. (emory.edu)
  • When the environmental condition is providing some selective factor onto the genes of the organism the proton enters a state of decoherence, or instability. (emory.edu)
  • Potential candidates for such a signature include so-called putative urovirulence factor (PUF) genes that have been found to be enriched in UTI-associated E. coli versus "regular" E. coli . (nih.gov)
  • Methods: Over a 5-year interval, patients in whom either E. coli or S. aureus was detected in superficial or primary sterile compartments were assessed for the primary endpoint death during hospital stay and the secondary endpoints duration of hospital stay and infectious disease as the main diagnosis. (scienceopen.com)
  • The hospital stay of patients with E. coli was increased due to third-generation cephalosporin and ciprofloxacin resistance, and in the case of patients with S. aureus due to tetracycline and fusidic acid resistance. (scienceopen.com)
  • Field emission scanning electron microscopy (FE-SEM) images verified that both E. coli and S. aureus cells were physically deformed and damaged the bacterial cell ultrastructure was observed. (nature.com)
  • Risk factors for acute prostatitis include urethral stricture, lower UTI (cystitis or urethritis), BPH, instrumentation of the lower urinary tract, and prostatic biopsy. (uspharmacist.com)
  • Risk factors for chronic prostatitis include anatomical or physiologic lower urinary tract obstruction (i.e., neurologic etiology), voiding dysfunction, pelvic floor muscle dysfunction, intraprostatic reflux of urate and creatinine, BPH, and lower UTI. (uspharmacist.com)
  • Due to various factors including socioeconomic factors, compliance is poor to anti-tuberculosis drugs, leading to resistance. (preprints.org)
  • Drug resistance (DR) is a complex process that occurs due to a variety of genetic and acquired factors. (preprints.org)
  • Ampicillin and Amoxicillin-clavulanic acid showed the highest resistance, while Imipenem was identified as a suitable antibiotic for treating BSIs by E. coli . (biomedcentral.com)
  • The genome of C. coli OR12 was sequenced to identify factors which contribute to its fitness in colonizing chickens. (nottingham.ac.uk)
  • Here, we present a system that can robustly integrate a linear DNA payload into the genome of E. coli by employing a Type I-F CRISPR-associated transposon from Vibrio cholerae . (biorxiv.org)
  • Recently, genome sequences revealed that in addition to rpoS , an rpoS -like sigma factor was found in V. alginolyticus 12G01. (hindawi.com)
  • In a recent study, scientists sought to determine whether there is a universal "genetic signature(s)" defining the ability of UPEC to cause disease. (nih.gov)
  • Two classes have been characterized: toxins, biological and surface adhesion molecules that affect the ability of the microorganism to invade and colonize a host. (lecturio.com)
  • E. coli is the most widely studied prokaryotic model organism, and an important species in the fields of biotechnology and microbiology, where it has served as the host organism for the majority of work with recombinant DNA. (wikipedia.org)
  • Virulence Virulence The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. (lecturio.com)
  • E. coli is the most common bacterial species in the human fecal flora due to its ability to colonize the human gastrointestinal tract. (biomedcentral.com)
  • Reactive oxygen species (ROS) are recently considered as common factors for bactericidal antibiotics-mediated cell death. (springeropen.com)
  • However, defined intestinal commensals such as E. coli and L. johnsonii have the potential to restore individual functions of intestinal and systemic immunity. (uni-kiel.de)
  • Adaptation of E. coli biofilm growth, morphology and mechanical properties to substrate water content. (hu-berlin.de)
  • Local c-di-GMP Signaling in the Control of Synthesis of the E. coli Biofilm Exopolysaccharide pEtN-Cellulose. (hu-berlin.de)
  • Klauck, G., D.O. Serra, A. Possling, and R. Hengge (2018) Spatial organisation of different sigma factor activities and c-di-GMP signalling within the 3D landscape of a bacterial biofilm. (hu-berlin.de)
  • This thesis has focused on introducing bifunctionality, the ability of the same engineered scaffold protein to exert more than one function, by applying different engineering approaches. (kth.se)
  • From this library, it was possible to achieve protein modules with the ability to simultaneously bind to its intended target as well as to human serum albumin (HSA), a feature that has been shown to increase the binder's half-life in the body. (kth.se)
  • Protein aggregation remains a significant problem in E. coli expression systems. (iucr.org)
  • Thus E. coli is literally dumb - but not deaf: it has a homolog of the V. fischeri LuxR protein, SdiA, which upon binding to one of various AHLs acts as transcriptional regulator. (asmblog.org)
  • A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. (lookformedical.com)
  • German paediatrician and bacteriologist Theodor Escherich discovered E. coli in 1885, and it is now classified as part of the Gammaproteobacterial family Enterobacteriaceae. (wikipedia.org)
  • proposed a common mechanism that ROS (especially hydroxyl radicals) could be considerable factors on bacterial PCD which was triggered by bactericidal antibiotics, but not by bacteriostatic antibiotics (Kohanski et al. (springeropen.com)
  • The evident advantage of these fusion proteins and their competency to be functionally produced in E. coli as well as the possibility to avoid an additional step of conjugation or coupling of affinity proteins to cytotoxic payloads, makes this approach a promising alternative for current procedures and another reason why ESPs are on the rise. (kth.se)
  • Sigma factors are a class of proteins constituting essential dissociable subunits that confer sequence-specific DNA binding properties to RNA polymerase (RNAP). (hindawi.com)
  • Several factors control the outbreaks to occur and collapse. (ac.bd)
  • It is generally encoded by the fliC gene[citation needed] There are 53 identified H antigens, numbered from H1 to H56 (H13 and H22 were not E. coli antigens but from Citrobacter freundii, and H50 was found to be the same as H10). (wikipedia.org)
  • If E.coli is grown on plates that are rich in lactose, a nutrient for growth, it has been shown that some colonies will develop a mutation that allows them to ferment or metabolize energy from lactose. (emory.edu)
  • These studies were conducted to determine if actin influences growth and haemolytic activity of E. coli. (microbiologyresearch.org)
  • Growth of E. coli in the presence of actin resulted in culture supernatant haemolytic activity that was 2.4-, 2.7- and 3.3-fold greater than that of E. coli grown in medium containing BSA, non-supplemented medium, or medium containing heat-denatured actin, respectively. (microbiologyresearch.org)
  • BACKGROUND: Progenipoietin-4 (ProGP-4) is an E. coli derived chimeric growth factor that activates the human Flt3 and G-CSF receptors. (medscimonit.com)
  • C. jejuni HPC5 counts invariably declined, whereas C. coli OR12 was capable of immediate growth within the caeca. (nottingham.ac.uk)
  • Furthermore, a previously developed ADAPT targeting the human epidermal growth factor receptor 2 (HER2) was genetically fused to an improved Horseradish Peroxidase (HRP) variant, thereby combining the idea of tumor-targeted therapy through the ADAPT with the utilization of HRP to enzymatically catalyze the prodrug IAA into its active form. (kth.se)
  • The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (lookformedical.com)
  • The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability. (lookformedical.com)
  • Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first identified as a growth factor due to its ability to induce proliferation and differentiation of bone marrow progenitors into granulocytes and macrophages. (leadgenebio.com)
  • IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. (peprotech.com)
  • Exposure of cells to soluble factors that damage cell membranes results in the release of actin into the extracellular spaces. (microbiologyresearch.org)
  • Cholesterol accessibility or the "ability" of cholesterol to interact with water-soluble molecules at the membrane surface, is modulated by the total cholesterol content and the composition of the membrane. (umass.edu)
  • Understanding the population structure of pathogenic E. coli is important, since it impacts the effectiveness of molecular epidemiological studies. (eurekaselect.com)
  • This factor is known mainly because of its chemotactic activity. (topsan.org)
  • National infectious disease surveillance systems form the foundation of our ability to know and track the routine. (cdc.gov)
  • It also supports the progression of certain auto immune diseases, possibly through its ability to induce the production and secretion of various pro inflammatory cytokines. (peprotech.com)
  • Measure by its ability to induce TF-1 cells proliferation. (leadgenebio.com)
  • These findings highlight that adding Cu to Ti can improve the antibacterial ability of the surface while inhibiting bacterial adherence. (nature.com)
  • Some shield E.coli from enzymes called lysozymes that break down the outer walls of their cells. (nationalgeographic.com)
  • Each binder was then examined for their usefulness as a real therapeutic by successfully evaluating its ability to block the interaction of the cytokine and its specific receptor in vitro . (kth.se)
  • Conventional mice were subjected to broad-spectrum antibiotic treatment for 8 weeks and perorally reassociated with E. coli, L. johnsonii or with a complex murine microbiota by fecal microbiota transplantation (FMT). (uni-kiel.de)