• There are a number of factors that can be altered to obtain optimum assay performance and thereby lead to higher molecular sensitivity, specificity and precision. (sigmaaldrich.com)
  • Whenever primer dimer products are produced and amplified, they divert reaction components away from synthesis of the desired product, thereby reducing assay efficiency and sensitivity. (sigmaaldrich.com)
  • Today we'll be discussing high-sensitivity troponin assays and how we use them or how we will be using them. (medscape.com)
  • So there is some degree of arbitrariness there, but most of the very high-sensitivity assays detect values in 80% to 100% of people, so it is very likely that those assays are substantially more sensitive. (medscape.com)
  • That said, the increased sensitivity of the assays does cause-for a larger number of patients-an earlier signal. (medscape.com)
  • Well, what's going to happen is that unstable angina , assuming the timing is right to look for a changing pattern of values-which is really key when you have high-sensitivity assays and particularly when we're detecting these other sources for cardiac injury-will go away, and you'll have [non-ST-elevation MI] non-STEMI. (medscape.com)
  • P erhaps most significantly are the big increases in assay sensitivity and the widening of the dynamic range accomplished by using alternatives to the traditional colorimetric detection, or by the use of new platform technologies. (ddw-online.com)
  • Studies using sera from COVID-19 patients showed that the immune response to SARS-CoV-2 infection is slow, with the initial IgM antibody response peaking at 9 days post-exposure and the IgG antibody response peaking at 11 days, 5,6 meaning that high sensitivity is particularly critical for any detection assay used in the early stages. (abcam.com)
  • The authors concluded that intrinsic subtypes, as determined by the Prosigna assay, are predictive of chemotherapy sensitivity, as referenced in the recently updated St. Gallen International Breast Cancer Guidelines. (clpmag.com)
  • Timed amyloid seeding assay achieves or surpasses sensitivity of currently available tests for transmissible spongiform encephalopathies, according to a report in The Journal of Molecular Diagnostics . (medicalnewstoday.com)
  • A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk. (medicalnewstoday.com)
  • They compared the sensitivity of the new assay technique, the timed prion seeding assay (tASA), to other currently available tests (two bioassays in laboratory rodents and three commercially available TSE rapid tests). (medicalnewstoday.com)
  • The report describes time specifications for the assay to help avoid false-positive results (30 hours) or false-negative results in weakly-positive samples (48 hours), as well as the number of replications necessary for adequate sensitivity (2-12). (medicalnewstoday.com)
  • Co-developed and validated with White Labs Yeast, this comprehensive system optimizes performance & sensitivity in cell dense, highly-competitive matrices instead of simply adapting finished beer assay workflows. (biomerieux.com)
  • The assay will be functionally equivalent, yet clinically superior, to whole metagenome sequencing, but at 1/10th the cost, 1/3rd the time, and several times the sensitivity. (labroots.com)
  • This necessitates an integrated clinical development plan, a systematic and comprehensive standardized scheme for sample procurement/processing, and biomarker assays including data analysis to be applied. (springer.com)
  • NEW YORK (GenomeWeb News) - South Africa's Centre for Proteomic and Genomic Research today said that it has entered into an agreement with SimuGen to develop biomarker assays for the prediction of toxicity of existing and new drug compounds. (genomeweb.com)
  • In this kinetic assay, agonist-induced release of Venus-tagged Gβγ subunits from Gα12 is followed in real time using nano-luciferase (Nluc)-tagged BRET donor. (nih.gov)
  • The GEN-PROBE APTIMA trichomonas vaginalis assay combines the technologies of target capture, Transcription-Mediated Amplification (TMA), and Dual Kinetic Assay (DKA). (cdc.gov)
  • For detection of cells general staining techniques (e.g. trypan blue) or special probes (e.g. mt-dehydrogenase detection with MTT assay) are used. (wikipedia.org)
  • Full validation of the above assays, including intra-assay/inter-assay variability, spike recovery, dilution linearity, and limit of detection, is not usually reported. (jneurosci.org)
  • With dye-based detection such as SYBR Green I, primer dimers also affect assay specificity because the nonspecific DNA-binding dye will bind to the primers and be detected along with the desired product. (sigmaaldrich.com)
  • FORT COLLINS, Colo. , Sept. 19, 2023 /PRNewswire/ -- GT Molecular, Inc., a company providing ultrasensitive PCR assays for wastewater-based epidemiology testing, pathogen detection, and cancer research is pleased to announce an agreement with Roche to provide a highly multiplexed respiratory panel for wastewater surveillance on the new Roche Digital LightCycler® System. (wreg.com)
  • Enzyme-linked immunosorbent assays (ELISA) have been around as one of the primary methods of analyte detection for more than four decades. (ddw-online.com)
  • The use of these assays could complement RNA detection strategies, providing information on the adapted immune response to SARS-CoV-2 infection, and aiding in infection control within the clinic and communities. (abcam.com)
  • GENE-UP® BREWPRO™ BACTERIA PLUS provides genomic-level detection of the lactic-acid bacteria species paired with risk-based detection by targeting the horA/horC hop resistance genes in the same assay. (biomerieux.com)
  • Similarly, when multiple targets are to be detected simultaneously in multiplex reactions, assay conditions must be optimized to detect all targets equally. (sigmaaldrich.com)
  • Using the Roche Digital LightCycler®, GT Molecular developed a multiplex assay kit targeting influenza A, influenza B, RSV A/B, SARS-CoV-2, along with all necessary controls. (wreg.com)
  • In vitro assays for measuring the cytotoxic capacity of immune cells have been a staple in laboratories for many years. (jove.com)
  • These in vitro assays involve the mixing of different cell populations, as well as using a relatively low number of both effector and target cells. (jove.com)
  • As with any assay examining the function of immune cells in vitro , there are a number of important considerations to consider improving the performance of the experiment. (jove.com)
  • miR-455 suppressed cell proliferation in vitro and in vivo, and it inhibited the abilities of cell invasion and EMT in HCC. (hindawi.com)
  • Bacteria often can't support over-expression needed to get workable quantities of protein for an assay, and in vitro expression often can't synthesize a fully functional transcription factor. (genomeweb.com)
  • Molecular Devices Corporation announced the launch of its QBT Fatty Acid Uptake Assay Kit, the first assay kit that addresses the need for a single-step, homogenous in vitro assay for fatty acid uptake for use in high- throughput screening and metabolic disease research. (news-medical.net)
  • The in vitro effects of the drugs on CRC cells were tested using CCK8 and flow cytometry assays. (lu.se)
  • Over the years many changes to the basic format have resulted in assay improvements, but some of the most recent look set to take the traditional ELISA to new levels. (ddw-online.com)
  • These include many vendors now addressing the automation of ELISA assays. (ddw-online.com)
  • Other automated instrumentation is designed to support the creation/coating of ELISA assay plates or contains cartridge-based delivery of assay reagents to reduce set-up time. (ddw-online.com)
  • These are supported by a wide range of ELISA reagents, assay and kits providing relative profiling or absolute quantitation of proteins across a wide range of study areas. (ddw-online.com)
  • E nzyme-linked immunosorbent assays (ELISA) have been one of the primary methods of detecting the presence of a substance, usually an antigen, in an aqueous sample for more than 40 years. (ddw-online.com)
  • The immunoassay landscape has, however, dramatically changed in recent years with the development of reduced assay steps protocols, no wash ELISAs and new automated systems designed to run ELISA. (ddw-online.com)
  • This review article uses as its starting point some of the findings of HTStec's ELISA Assay Trends 2012 survey and report, published in June 2012 (1). (ddw-online.com)
  • This report discusses end-users' current practices and preferences in ELISA assays, and seeks to understand future user requirements. (ddw-online.com)
  • The main (primary) application area for survey respondents' ELISA assays was immunology (17% selecting). (ddw-online.com)
  • Serological assays detecting antibodies to SARS-COV-2 would therefore be useful to speed diagnosis, determine the immunity period for SARS-CoV-2, and re-admit people to work following potential infection 1,2 . (abcam.com)
  • The first laboratory study testing the omicron variant of the coronavirus against the Pfizer-BioNTech vaccine shows the variant has significant, but not total, ability to evade the virus-fighting antibodies that are a key line of defense. (ibj.com)
  • In a preprint paper not yet peer-reviewed, scientists in South Africa reported a large, 41-fold drop in antibodies' virus-blocking ability - "much more extensive escape" than seen against previous variants using similar experiments. (ibj.com)
  • Omicron evades most of the vaccine response," said Michel C. Nussenzweig, a Rockefeller University investigator who was not part of the South Africa research team but whose experiments predicted a similar drop in antibodies' neutralizing ability. (ibj.com)
  • Some of those mutations impair the ability of antibodies to bind with the virus and potentially prevent it from infecting a cell. (ibj.com)
  • Cell viability and invasion were measured by CCK8 and Transwell assays. (hindawi.com)
  • Next, the effects of miR-637 on glioma cell migration and invasion were determined by using the transwell assay. (scirp.org)
  • The assay may be used in accordance with clinical guidelines for cervical cancer screening to identify the presence of high-risk types. (uspharmacist.com)
  • A large number of different assays for measuring T cell quality and function has been developed and applied in such clinical trials. (springer.com)
  • This would offer clinical advantages, such as the ability to sample blood instead of relying on more invasive tissue biopsy and to screen blood donations for contamination. (medicalnewstoday.com)
  • Antibacterial activity of the oil was evaluated by microbroth dilution assay against clinical isolates of methicillin -resistant (MR) and methicillin-sensitive (MS) strains of S. aureus. (unboundmedicine.com)
  • the lack of appropriate assays--many of which are still in developmental stages and are not readily available to clinical laboratories, and 2) inadequately or improperly collected specimens. (cdc.gov)
  • RET fusion positivity, as determined by a Clinical Laboratory Improvement Amendments or equivalently certified next generation sequencing (NGS) assay (tissue or blood). (who.int)
  • Because the technical validation of assays for measuring cellular immune biomarkers is not trivial, systematic mono- and multi-center efforts have been initiated in the different fields of cancer immunology, autoimmunity and infectious diseases to harmonize and standardize T cell assays. (springer.com)
  • The lower limit of reliable quantification of the assay was 0.18 pg/ml and the antibody pairs recognized Aβ multimers comprised of either synthetic standards, or endogenous oligomers isolated from confirmed human AD and healthy control brain. (jneurosci.org)
  • Claims relating to the performance of assays should be verified under the conditions of the study, including test samples, specific reagents and the instrument of choice. (sigmaaldrich.com)
  • However, all assays have a set of optimal conditions and these are dependent on the instrument, selected reagents (buffer conditions), primer concentration and/or annealing temperature (T a ), magnesium concentration and even ramp rate. (sigmaaldrich.com)
  • Read our white paper on key considerations for optimal lyophilized reagent development and view the NEB TV webinar on lyophilizing reagents: requirements, challenges, and considerations for assay developers. (neb.com)
  • Over the past few years a number of critical assay parameters have been identified which influence test performance irrespective of protocol, material, and reagents used. (springer.com)
  • We sought to develop a robust assay to quantify oligomers from CSF. (jneurosci.org)
  • Roche Digital LightCycler® System affords the ability to simultaneously co-quantify six targets in a single well. (wreg.com)
  • We demonstrated the utility of this assay to quantify rates of G protein activation and inactivation as well as performing dose-response studies while rank ordering signalling via individual Gα subunits. (nih.gov)
  • This whitepaper describes assay and system compatibility with various workflows, wastewater inhibition, longitudinal studies for monitoring atypical seasonal behavior. (wreg.com)
  • The work we will do with Simugen, aimed at improving the ability to develop novel, safe drugs, fits perfectly into our vision of creating cutting-edge ex-vivo drug screening workflows that make full use of our genomic and proteomic platforms," Reinhard Hiller, managing director of CPGR, said in a statement. (genomeweb.com)
  • Validation of primer design is particularly important when adopting primers from a previous publication or using a commercially supplied assay. (sigmaaldrich.com)
  • The ability of primers to hybridize to one another, especially at the 3'-end, may lead to primer extension during PCR and the formation of target-independent products, known as primer dimers. (sigmaaldrich.com)
  • Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. (cdc.gov)
  • The aim of our work was the study of the interaction of three red wine polyphenols-quercetin, resveratrol and caffeic acid-alone and in their equimolar binary and ternary mixtures in different antioxidant/scavenging assays (inhibition of 2-deoxy-D-ribose degradation by hydroxyl radical, FRAP, Fe(III) reducing power, DPPH, ABTS and NO scavenging, respectively). (mdpi.com)
  • Many assays to evaluate the nature, breadth, and quality of antigen-specific T cell responses are currently applied in human medicine. (springer.com)
  • Using this assay, we expected to evaluate the PAR 1 /PAR 2 selectivity of the compounds listed in Table 1 . (aspetjournals.org)
  • The assay could help accelerate efforts to map where transcription factors bind the genomes of humans and model organisms, Deplancke said. (genomeweb.com)
  • Introduction of the Gα12-coupling BRET assay is expected to accelerate characterization of GPCR actions on this understudied G protein. (nih.gov)
  • Together with the inherent complexity of cellular assays, this leads to unnecessary limitations in the ability to compare results generated across institutions. (springer.com)
  • The reader is guided through possible limitations of the assay, and advantages and disadvantages of the method compared to other feeding assays in D. melanogaster are evaluated. (jove.com)
  • The QBT Fatty Acid Uptake Assay removes these limitations by providing a rapid, reproducible, inexpensive method for laboratory screening. (news-medical.net)
  • The efficacy of adjuvants in the IL-6 KO environment cannot be solely attributed to their ability to stimulate antigen-specific cellular responses, suggesting that other biological activities of IL-6 are also important. (nih.gov)
  • Addressing the need to define steadfast analytical performance criteria for prion amyloid seeding assays (ASAs), researchers developed a method to measure prion protein conversion time (from normal cellular form to prion form) by a combination of statistical analyses to obtain a prion-detecting ASA with a known degree of confidence. (medicalnewstoday.com)
  • In a paper published in Nature Methods this week, a Switzerland-based team of researchers, led by bioengineer Bart Deplancke of the École Polytechnique Fédérale de Lausanne (EPFL), showcased the assay's ability to determine DNA-binding specificities for transcription factors. (genomeweb.com)
  • Though many researchers are working to develop serological assays to detect SARS-CoV-2 infection, a thorough understanding of the antibody response in COVID-19 has restricted the speed of development in this field. (abcam.com)
  • The CAFE assay is one of several behavioral paradigms used to measure feeding in Drosophila melanogaster and researchers have to choose the most appropriate one for their specific question. (jove.com)
  • Conventional assays using radioisotopes are expensive and time-consuming and have limited the ability of drug researchers to identify potential new drugs via high-throughput screening. (news-medical.net)
  • Susan Williams-Clark, Director of Marketing at Molecular Devices stated, "Working together with researchers at the Palo Alto Medical Foundation's Research Division, we have applied our proprietary quench technology to develop the first single-step homogenous assay for fatty acid uptake. (news-medical.net)
  • Williams-Clark continued, "Prior to the development of this assay, it was extremely difficult for drug discovery researchers to study fatty acid uptake processes and identify new regulators. (news-medical.net)
  • The ability to develop complex, yet simple to use lyophilized products enables us to provide a more complete solution for our customers, particularly those in the molecular diagnostics space. (neb.com)
  • In general, the most important requisite is to calibrate the incubation time of the assay both to the model cell and the ligand to be evaluated. (wikipedia.org)
  • These assays have been used to determine the ability of T cells, NK cells, or any other immune cell to kill target cells in an antigen-specific or -nonspecific manner. (jove.com)
  • Thus, having an assay in which the user can easily integrate any number of different effector cells, target cells, and/or response modifiers into the experimental design can serve as a valuable means of quickly assessing the cytotoxic capacity of effector cells and/or the responsiveness of the target cell. (jove.com)
  • In this assay hematopoietic cells are cultured in MyeloCult™ medium with supportive human or mouse stromal cell layers and tested for their ability to generate myeloid clonogenic progenitors for several weeks as assayed by replating the cells in a colony-forming unit (CFU) assay using MethoCult™ medium. (stemcell.com)
  • To this end, the Minimal Information About T Cell Assays (MIATA) project was initiated. (springer.com)
  • The objective of MIATA is to achieve a broad consensus on which T cell assay parameters should be reported in scientific publications and to propose a mechanism for reporting these in a systematic manner. (springer.com)
  • These harmonization efforts increased the awareness to the problem that, despite the vast body of literature describing results from T cell assays, the majority of scientific publications lack important information on crucial steps in the assay process, precluding a full understanding and accurate interpretation of published data sets and limiting the ability to reproduce results and compare data sets between centers or perform meta-analysis. (springer.com)
  • Similar to Molecular Devices' FLIPR Assay Kits, the QBT Fatty Acid Uptake Assay eliminates the need for cell washing steps, resulting in a faster, more streamlined route to drug discovery. (news-medical.net)
  • The abilities of the PAR 1 -targeted agents to desensitize or block PAR 1 in the HEK cell assay were compared with their activities in a human platelet aggregation assay. (aspetjournals.org)
  • Our data illustrate the usefulness of the HEK cell assay for evaluating the PAR 1 /PAR 2 selectivity of PAR-activating agonists. (aspetjournals.org)
  • Natural-killer (NK) cells are specialized lymphocytes that have cytotoxic properties in addition to their ability to produce cytokines that assist in the orchestration of adaptive immunity. (medscape.com)
  • Herein we describe step-by-step the method from setup to successful execution of the CAFE assay, and provide practical examples to analyze the food intake of a group of flies under controlled conditions. (jove.com)
  • We developed a calcium signaling-based assay, using cultured human embryonic kidney cells (HEK), that evaluates simultaneously, the activation/desensitization or blockade of the proteinase-activated receptors, PAR 1 and PAR 2 . (aspetjournals.org)
  • To this end, we developed a calcium-signaling assay, employing cultured human embryonic kidney cells (HEK293) in which the action of PAR 1 and PAR 2 agonists and antagonists could be evaluated simultaneously. (aspetjournals.org)
  • Describing these critical factors as an integral part of any published report will both facilitate the comparison of data generated across institutions and lead to improvements in the assays themselves. (springer.com)
  • This rapid extraction process is demonstrated to be compatible with standard inductive coupled plasma mass spectrometry methods for uranium isotopic assay as well as screening techniques such as x-ray fluorescence. (osti.gov)
  • It is a conversion assay that uses recombinant prion-related protein as a substrate and detects conversion via changes in fluorescence. (medicalnewstoday.com)
  • Since this assay uses a fluorescence-based readout rather than a radioactivity-based one, it eliminates the safety risks associated with conventional radiolabel assays, in addition to being faster and easier to perform. (news-medical.net)
  • In most cases, assay-related protocols are developed on an individual laboratory basis, resulting in a large number of different protocols being applied worldwide. (springer.com)
  • Extraction methods enabling faster removal and concentration of uranium compounds for improved trace and low-level assay are demonstrated for standard surface sampling material in support of nuclear safeguards efforts, health monitoring, and other nuclear analysis applications. (osti.gov)
  • In such methods, there is a continuous concern regarding the ability to locate and quantitatively sample the analyte species from the material. (osti.gov)
  • METHODS: Static-binding assays were used to probe the interaction between Angpt-2 and VWF. (imperial.ac.uk)
  • The development of fatty acid uptake regulators as potential drugs is dependent upon having a rapid assay that can be used in high-throughput screening. (news-medical.net)
  • Another important mechanism for the progression of colorectal cancer is the ability of the transformed cells to invade and traverse the basement membrane, which in turn facilitates the conversion of adenomas into carcinomas and then metastases ( 1 ). (spandidos-publications.com)
  • Chemotaxis assays are experimental tools for evaluation of chemotactic ability of prokaryotic or eukaryotic cells. (wikipedia.org)
  • Labelled (e.g. fluorochromes) cells are also used, in some assays cells get labelled during transmigration the filter. (wikipedia.org)
  • Thus, one necessity of the assay is to label the target cells in a manner that can easily be detected and quantitated, allowing the user to then determine the 'percent specific lysis' mediated by the effector cells. (jove.com)
  • The short labeling and total assay times reduces the potential for significant changes in the number and/or phenotype of the target cells, which could influence the outcome of the assay. (jove.com)
  • Luciferase reporter assay was performed to verify that miR-455 directly binds to the 3′-noncoding region (UTR) of RAB18 mRNA in Huh7 cells. (hindawi.com)
  • Recently, a number of studies have confirmed that ADSCs possess the ability to differentiate into adipocytes, osteoblasts, and chondrocytes [ 16 - 18 ], suggesting that a broader source of stem cells is available for application in tissue engineering. (hindawi.com)
  • Here, we present an adaptation of the bioluminescence resonance energy transfer (BRET)-based assay to specifically monitor activity of Gα12 in living cells. (nih.gov)
  • Adipose tissue-derived stem cells (ADSCs) have been characterized as having the ability to self-renew and differentiate into different connective tissue cells, including osteoblasts, adipocytes, chondrocytes and myocytes, under specific inductive stimuli ( 4 ). (spandidos-publications.com)
  • To identify why preparations may differ, both endoprotease activity plus ability of the toxin complex to adhere to cells and be transported to where it acts must be monitored. (inderscience.com)
  • The PAR 1 -selective agonist that we developed using the assay should prove useful for studying the effects of selectively activating PAR 1 in vivo. (aspetjournals.org)
  • In terms of predicting where in the genome the transcription factors bind, the models we're able to derive seem to be, in general, actually better than the other assays. (genomeweb.com)
  • This is due to its ability to detach from lysed RBCs and subsequently bind intact erythrocytes with changes in temperature. (medscape.com)
  • We investigated the role of IL-6 on the ability of nine adjuvant formulations to induce antibody responses to the Plasmodium falciparum MSP1-19 malaria vaccine, using IL-6-/- (KO) mice. (nih.gov)
  • 2006). The LLNA is based upon characterization of chemicals comprising allergens of different potencies and non- induced proliferative responses in draining lymph nodes allergenic chemicals were evaluated for their ability to react with following topical exposure of mice to chemicals (Gerberick reduced glutathione (GSH) or with two synthetic peptides et al. (cdc.gov)
  • Scientists had previously shown, through experiments, the immune-evading abilities of some of the dozens of mutations that have made omicron a "variant of concern. (ibj.com)
  • When the SARS-CoV-2 Alpha variant emerged in late 2020, a spike gene (S-gene) deletion (69-70) in the N-terminal region, which might compensate for immune escape mutations that impair infectivity (1), resulted in reduced or failed S-gene target amplification in certain multitarget reverse transcription-polymerase chain reaction (RT-PCR) assays, a pattern referred to as S-gene target failure (SGTF) (2). (cdc.gov)
  • Validation provides the data required to justify the continued use of the assay in further research projects 1 . (sigmaaldrich.com)
  • NEW YORK (GenomeWeb) - A new microfluidics-driven DNA-protein binding assay has its creators dreaming of launching a startup to cash in on several potential applications. (genomeweb.com)
  • Furthermore, we used this assay to develop a PAR 1 receptor-activating probe [Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH 2 (Cit-NH 2 )], which displays a high degree of specificity for PAR 1 over PAR 2 , and we used the assay to quantitate the ability of trypsin to disarm the activation of PAR 1 by thrombin. (aspetjournals.org)
  • Histopathological changes were observed using hematoxylin and eosin staining, and the terminal deoxynucleotidyl transferase dUTP nick end labeling assay was used to examine myocardial apoptosis. (bvsalud.org)
  • Optimization is required to ensure that the assay is as sensitive as is required and that it is specific to the target of interest. (sigmaaldrich.com)
  • We believe that the QBT Fatty Acid Uptake Assay Kit will enable high-throughput screening of these drug targets and enhance fatty acid metabolism research. (news-medical.net)
  • Assays purchased from skilled commercial providers still require validation within the laboratory in which they are being used. (sigmaaldrich.com)
  • Using the assay, a significant 3- to 5-fold increase in Aβ oligomers in human AD CSF compared with comparably aged controls was demonstrated. (jneurosci.org)
  • Assays requiring high specificity are particularly vulnerable when performed without optimization and adequate controls. (sigmaaldrich.com)
  • The study demonstrated that ROR score and intrinsic subtype as determined by the Prosigna assay are strong predictors of response to NAC, confirming expectations that high-risk tumors are significantly more responsive to systemic chemotherapy than low-risk tumors. (clpmag.com)
  • RESULTS: Static-binding assays revealed that Angpt-2 bound to VWF with high affinity (KD,app ∼3 nM) in a pH and calcium-dependent manner. (imperial.ac.uk)
  • Neonicotinoids can alter bee navigation, but we present the first evidence that neonicotinoid exposure alone can impair the physical ability of bees to fly. (nature.com)
  • TMX may similarly impair navigation 26 , but we tested the hypothesis that it reduces the physical ability of bees to fly. (nature.com)
  • Thus, characteriza- tion of skin sensitization must integrate various sources of information from a battery of assays representing the key steps of skin allergy (Jowsey et al. (cdc.gov)
  • We concluded that lox66 and lox 71 incorporated into Char are dysfunctional or have very low excision efficiency and furthermore,on-CMV plasmid can be a good read-out system for Cre activity assay. (igem.org)
  • The factor VII assay is a blood test to measure the activity of factor VII. (medlineplus.gov)
  • The essential oil exhibited synergism with vancomycin and displayed the ability to enhance the activity of vancomycin. (unboundmedicine.com)
  • Some people have gained improved exercise ability and better lung function after surgery. (medlineplus.gov)
  • Immunofluorescence was used to detect the presence of Angpt-2 on VWF strings, and flow assays were used to investigate the effect on VWF function. (imperial.ac.uk)
  • En vous déconnectant d'EU Login, vous vous déconnecterez de tous les autres services utilisant votre compte EU Login. (europa.eu)
  • A major challenge to assessing the role of Aβ oligomers in AD is the lack of qualified assays. (jneurosci.org)