• Generally, when estrogen is prescribed for a postmenopausal woman with a uterus, a progestin should also be considered to reduce the risk of endometrial cancer. (pillintrip.com)
  • Three independent case control studies have reported an increased risk of endometrial cancer in postmenopausal women exposed to exogenous estrogens for prolonged periods. (rxlist.com)
  • Age group 12-49 (Paternal age effect) Aneuploidy, an abnormal number of chromosomes Centriole Neoplasm, e.g. seminoma Idiopathic failure Cryptorchidism Trauma Hydrocele, particularly hydrocele testis Hypopituitarism in adults, and hypopituitarism untreated in children (resulting in growth hormone deficiency and proportionate dwarfism. (wikipedia.org)
  • Adequate diagnostic measures, including directed or random endometrial sampling when indicated, should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding. (pfizermedicalinformation.com)
  • Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. (lookformedical.com)
  • A woman without a uterus does not need a progestin. (pillintrip.com)
  • Clinical responses (relief of symptoms) at the lowest effective dose should be the guide for establishing administration of the Linoladiol transdermal system, especially in women with an intact uterus. (pillintrip.com)
  • In patients with an intact uterus, PREMARIN should be prescribed with an appropriate dosage of a progestin for women with intact uteri, in order to prevent endometrial hyperplasia/carcinoma. (pfizermedicalinformation.ca)
  • The Women's Health Initiative (WHI) study reported increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) during 5 years of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone acetate (MPA 2.5 mg) relative to placebo. (theodora.com)
  • The Women's Health Initiative Memory Study (WHIMS), a substudy of WHI, reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 4 years of treatment with oral conjugated estrogens plus medroxyprogesterone acetate relative to placebo. (theodora.com)
  • It is unknown whether this finding applies to younger postmenopausal women or to women taking estrogen alone therapy. (theodora.com)
  • When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and non-estrogen medication should be carefully considered. (pillintrip.com)
  • Postmenopausal women should be reevaluated periodically as clinically appropriate to determine if treatment is still necessary. (pillintrip.com)
  • When prescribing solely for the prevention of postmenopausal osteoporosis, therapy with PREMARIN should be considered in light of other available therapies (see Boxed Warning ) and should only be considered for women at significant risk of osteoporosis. (pfizermedicalinformation.ca)
  • Postmenopausal women require an average of 1000 mg to 1500 mg/day of elemental calcium. (pfizermedicalinformation.ca)
  • Vitamin D supplementation of 400-800 IU/day may also be required to ensure adequate daily intake in postmenopausal women. (pfizermedicalinformation.ca)
  • The Women's Health Initiative (WHI) trial examined the health benefits and risks of oral combined estrogen plus progestin therapy (n=16,608) and oral estrogen-alone therapy (n=10,739) in postmenopausal women aged 50 to 79 years. (pfizermedicalinformation.ca)
  • Concomitant administration of bazedoxifene (40 mg daily) and atorvastatin (20 mg, single-dose) to healthy postmenopausal women did not affect the pharmacokinetics of bazedoxifene, atorvastatin or its active metabolites. (pfizermedicalinformation.com)
  • 70% to minimize the occurrence of genital warts and anal intraepithelial neoplasia [ 3 , 4 , 7 , 12 ]. (clinmedjournals.org)
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  • EEMT (esterified estrogens and methyltestosterone) is a combination of the female hormone estrogen and the male hormone testosterone used to treat moderate to severe vasomotor symptoms associated with menopause in those patients not improved by estrogens alone. (rxlist.com)
  • GONAL-f in association with a luteinising hormone (LH) preparation is indicated for the stimulation of follicular development in women with severe LH and FSH deficiency. (medthority.com)
  • Sentinel lymph node biopsy (SLNB) is generally indicated for pathologic staging of the regional nodal basin(s) for primary tumors greater than 1 mm depth and when certain adverse histologic features (eg, ulceration, high mitotic rate, lymphovascular invasion) are present in thinner melanomas. (medscape.com)
  • The use of female sex hormones, both estrogens and progestogens, during early pregnancy may seriously damage the offspring. (rxlist.com)
  • If pregnancy is not desired, the removal should be carried out within 7 days of the onset of menstruation, provided the woman is still experiencing regular menses. (medscape.co.uk)
  • If the system is removed at some other time during the cycle or the women does not experience regular menses and the woman had has intercourse within a week, she is at risk of pregnancy. (medscape.co.uk)
  • Combination hormonal contraceptives are generally not associated with any adverse effects on the fetus or mother if used inadvertently early in pregnancy. (emedz.net)
  • Close clinical surveillance of all women taking estrogens is important. (theodora.com)
  • Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. (theodora.com)
  • Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. (theodora.com)
  • Several reports suggest an association between intrauterine exposure to female sex hormones and congenital anomalies, including congenital heart defects and limb reduction defects. (rxlist.com)
  • The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secrets 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. (nih.gov)
  • Anovulation (including polycystic ovarian syndrome) in women who have been unresponsive to treatment with clomiphene citrate. (medthority.com)
  • Therefore, it is considered appropriate to give a lower total dose of GONAL-f than generally used for urinary FSH, not only in order to optimise follicular development but also to minimise the risk of unwanted ovarian hyperstimulation. (medthority.com)
  • The occurrence of acute movement disorders on exposure to dopamine antagonists is increased in female patients and older patients. (medscape.com)
  • ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. (wikipedia.org)
  • The estrous cycle comprises the recurring physiologic changes that are induced by reproductive hormones in most mammalian placental females. (absoluteastronomy.com)
  • Stimulation of multifollicular development in women undergoing superovulation for assisted reproductive technologies (ART) such as in vitro fertilisation (IVF), gamete intra-fallopian transfer and zygote intra-fallopian transfer. (medthority.com)
  • For older women who are not experiencing any more acute symptoms of menopause, use in combination with a progestin should only be considered for women who failed on, or were intolerant of, non-estrogen medication. (pfizermedicalinformation.ca)
  • Overdosage with estrogen may cause nausea, breast discomfort, fluid retention, bloating or vaginal bleeding in women. (pfizermedicalinformation.ca)
  • It has been shown that females exposed in utero to diethylstilbestrol, a non-steroidal estrogen, have an increased risk of developing in later life a form of vaginal or cervical cancer that is ordinarily extremely rare. (rxlist.com)
  • Melanoma is a malignancy of pigment-producing cells (melanocytes) located predominantly in the skin but also found in the eyes, ears, GI tract, leptomeninges, and oral and genital mucous membranes. (medscape.com)
  • Pregnant women should not use it. (emedz.net)
  • Late diagnoses are based on the male chauvinist culture that self-care with men's health configures a role of passivity, dependence, and male fragility, primarily when related to the genital organ. (clinmedjournals.org)
  • it occurs primarily in females and on occasion in males. (beds.ac.uk)
  • A female in her teens ( randomization number 104650 ) was diagnosed with right lower extremity deep vein thrombosis on Nov. 15, 2020, which was still ongoing as of Mar. 29, 2021, the date of the CRF. (thelibertybeacon.com)
  • Male infertility refers to a sexually mature male's inability to impregnate a fertile female. (wikipedia.org)
  • Estrous cycles start after puberty in sexually mature females and are interrupted by anestrous phases or pregnancies. (absoluteastronomy.com)
  • In some cases, however, hysterectomized women with a history of endometriosis may need a progestin. (pillintrip.com)
  • Use of estrogen-alone, or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. (pillintrip.com)
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  • In menstruating women treatment should commence within the first 7 days of the menstrual cycle. (medthority.com)
  • Therefore, when not contraindicated, calcium supplementation may be helpful for women with suboptimal dietary intake. (pfizermedicalinformation.ca)
  • Penile cancer is a rare neoplasm in the United States and Europe, accounting for less than 1% of cancers in men. (clinmedjournals.org)
  • Brazil is one of the countries with the highest incidence of penile cancer in the world [ 5 , 6 ] which may correspond to 2.1% of all neoplasms in men, being five times more prevalent in the North and Northeast regions [ 7 ], where most of the procedures are performed. (clinmedjournals.org)
  • Absorption through the skin in the genital area is rapid enough to approximate the effect of injecting the pesticide directly into the bloodstream. (ufl.edu)
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  • Manufacturers advise that women who have chosen not to breastfeed should not start combination hormonal contraceptives until 4 to 6 weeks after birth. (emedz.net)
  • Combination hormonal contraceptives should be used in women 21 to 42 days after birth. (emedz.net)
  • Women who use combination hormonal contraceptives must take into account the risk factors for VTE. (emedz.net)
  • Due to the increased risk of venous embolism, breastfeeding women should wait at least 21 days following delivery before using combination hormonal contraceptives (VTE). (emedz.net)
  • Consider estrogen therapy only for women at significant risk of osteoporosis. (nih.gov)
  • The device will be effective for up to 5 years after which the device may be removed and if the women wishes to continue using the same method immediately replaced with a new system. (medscape.co.uk)
  • A female in her early 50s ( randomization number 86545 ) who participated in the trial at the Sterling Research Group in Cincinnati, Ohio, died of an apparent myocardial infarction on Nov. 4, 2020. (thelibertybeacon.com)
  • Use for female contraceptive agents in general or for which there is no specific heading. (lookformedical.com)
  • The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. (lookformedical.com)