Virus nodaviridae. Medical search. Frequent questions

BBV is a (+)ssRNA virus from the family Nodaviridae and of the genus Alphanodavirus. (wikipedia.org)
Multiple alignment and phylogenetic analysis clearly supported including this virus in the species Redspotted grouper nervous necrosis virus, genus Betanodavirus, family Nodaviridae. (elsevierpure.com)
A genus of NODAVIRIDAE infecting insects. (nih.gov)
A genus of NODAVIRIDAE infecting juvenile marine fish. (nih.gov)
Betanodavirus or nervous necrosis virus (NNV) is a viral genus classified in the family Nodaviridae. (ximbio.com)
Tibrovirus is a poorly characterized genus of viruses in the family Rhabdoviridae , order Mononegavirales . (wikimili.com)

BBV comes from the family of Nodaviridae that contains nine different viruses divided into two different sub groups: Alphanodavirus and Betanodavirus. (wikipedia.org)

1. Arimoto M, Mushiake K, Mizuta Y, Muroga K and Furusawa I. Detection of striped jack nervous necrosis virus (SJNNV) by enzyme-linked immunosorbent assay (ELISA). (gov.tw)

A family of insect viruses causing disease in lepidopterous larvae, most commonly from species of the owlet moth family Noctuidae. (bvsalud.org)

however it cannot replicate in mammalian cells like other viruses in its family. (wikipedia.org)
citation needed] The structure of BBV is similar to the other viruses in its family. (wikipedia.org)
The genome of BBV and other viruses in its family are incredibly small, nearly half the size of picornaviruses, making it the smallest class of virus with a segmented genome. (wikipedia.org)
However, it is respectively assumed to follow the path of other viruses of the same family. (wikipedia.org)
A family of RNA viruses infecting insects and fish. (uams.edu)
A family of RNA viruses infecting INSECTA and fish. (nih.gov)
A family of invertebrate RNA viruses in the order Picornavirales. (bvsalud.org)
A family of small RNA viruses comprising some important pathogens of humans and animals. (nih.gov)
A family of viruses, mainly arboviruses, consisting of a single strand of RNA. (ouhsc.edu)
Parvoviruses are a family of animal viruses that constitute the family Parvoviridae . (mdwiki.org)

Beatrice Hill virus (BHV) was isolated from a pool of biting midges (Culicoides peregrinus) in 1984 in Northern Territory, Australia. (wikimili.com)

The genome and viral messenger for (+)ssRNA noroviridae viruses is the initial virion RNA. (wikipedia.org)

The BBV insect virus genome is made of two mRNA molecules encapsidated in a single virion. (wikipedia.org)
Twarock hoped to go further than this, to model the three-dimensional protein structure and interior of viruses where their genome is packaged. (wikipedia.org)
The models turned out to be useful for studying the assembly of RNA viruses , which involves proteins binding to specific parts of the genome that end up in 3-dimensional locations [8] that can be determined mathematically. (wikipedia.org)
Virus genome sequence data provide the best evidence of transmission. (cdc.gov)
Flock House virus (FHV) is a positive-sense RNA insect virus with a bipartite genome. (cnrs.fr)
In their replication cycle, viruses must generate a protective shell (or capsid) to ferry their genome between hosts. (gla.ac.uk)
Thus virus particles are dynamic entities, molecular machines evolved to provide a robust protective shell for the genome and capable of undergoing dramatic conformational changes upon infection of a host cell and in response to specific environmental stimuli. (gla.ac.uk)
Parvovirus virions are small compared to most viruses, at 23-28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. (mdwiki.org)

BBV, Flock House, and nodavirus are all group IV viruses with varying abilities to infect other animals in terms of species specificity. (wikipedia.org)
Of human transmissible virus, 37 species have so far been restricted to self-limiting outbreaks. (cdc.gov)
However another virus (LcEV) has also been described as causing encephalitis in the same species. (fishvetapp.com)
The fact that many viruses generate their capsids from only one or two protein species makes them all the more remarkable. (gla.ac.uk)

Once in the cell, the virus uncoats itself and releases the genomic RNA into the cytoplasm of the cell. (wikipedia.org)
Virus assembly in the cytoplasm around genomic RNA1 and RNA2. (expasy.org)

RNA1 sequence encodes for the virus' RNA-dependand RNA polymerase which is protein A. Thee virion also contains code for RNA2 which forms a precursor protein for capsid formation. (wikipedia.org)

BBV is recognized as a member of a group of small split arboviruses from the same line as Nodamura virus which was discovered 20 years prior to BBV in Japan. (wikipedia.org)
Viruses such as Nodamura Virus and Flock house virus have been shown to infect mammals and fishes. (wikipedia.org)

Nodaviridae" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)

Consistent with published results, we found that RNA replication was indeed vigorous but the yield of progeny virus was negligible. (cnrs.fr)
[10] EKV-1 could not be isolated from the patient's blood sample and live replication-competent virus is not available. (wikimili.com)
Parvoviruses are believed to be descended from ssDNA viruses that have circular genomes that form a loop because these viruses encode a replication initiator protein that is related to NS1 and have a similar replication mechanism. (mdwiki.org)
Animal parvoviruses were first discovered in the 1960s, including minute virus of mice , which is frequently used to study parvovirus replication. (mdwiki.org)

The genomes of these viruses are unusually small compared to others such as picorna and retroviruses. (wikipedia.org)
The virus genomes are linear and segmented, bipartite, around 21.4kb in length as well. (wikipedia.org)

The results identified sequences related to 51 different viral families, including vertebrate, invertebrate, and plant viruses. (mdpi.com)

The disease has also been reported in Tilapia larvae, and is described as a herpes-like virus. (fishvetapp.com)
Studies of rapid and sensitive diagnostics tool or commercial vaccine to identify the risk of presence of the virus in brood fish and to enable stocking of virus free larvae and juveniles would be the ideal means of controlling the disease. (ximbio.com)
This antibody would be useful to develop diagnostic assays to identify the virus in brood fish and to enable stocking of virus free larvae and juveniles. (ximbio.com)

These viruses are non-enveloped, with icosahedral geometries, and T=3 symmetry. (wikipedia.org)
[4] Almost all icosahedral viruses have proteins on their capsids arranged in clusters of five and six, with a structure permitting at most 12 clusters of five, but papovaviridae, including HPV , have 72 clusters of five [5] This protein layout did not correspond to any spherical polyhedron known to mathematics. (wikipedia.org)
The viruses appear to use these patterns because they are the most stable way of connecting multiple interacting layers that all have icosahedral symmetry . (wikipedia.org)

In order to shed some light into this genetic dark matter we expanded the search of orthologous groups as potential markers to viral taxonomy from bacteriophages and included eukaryotic viruses, establishing a set of 31,150 ViPhOGs (Eukaryotic Viruses and Phages Orthologous Groups). (mdpi.com)

Experiments using a recombinant vesicular stomatitis virus expressing the EKV-1 envelope glycoprotein indicate EKV-1 has very broad tropism and can efficiently enter nearly all types of human cells. (wikimili.com)
Experiments using a recombinant vesicular stomatitis virus expressing the EKV-2 envelope glycoprotein indicate EKV-2 has very broad tropism similar to EKV-1. (wikimili.com)
In medicine, recombinant adeno-associated viruses (AAV) have become an important vector for delivering genes to the cell nucleus during gene therapy . (mdwiki.org)

On the basis of comparisons across all recognized human viruses, we consider the characteristics of these priority viruses and assess the likelihood that they will further emerge in human populations. (cdc.gov)

We also assess the likelihood that a virus that can infect humans but is not capable of transmission (directly or by a vector) between human hosts can acquire that capability. (cdc.gov)
However, there is some consensus, at least in general terms, regarding the kinds of traits that are most essential in determining the capacity of a virus to infect, cause disease, and spread within human populations ( Table 1 ). (cdc.gov)
Level 1 indicates viruses to which humans are exposed but which do not infect humans. (cdc.gov)
Level 2 indicates viruses that can infect humans but. (cdc.gov)

It was known that, using rotations, virus protein patterns could be generated from a single shape by making copies of it and moving them around in ways that preserve the symmetry. (wikipedia.org)

These patterns turned out to accurately predict the shape and size of the proteins, as well as the structure of packaged genetic material, for many viruses including Nodaviridae . (wikipedia.org)
This group applies the techniques of electron-cryomicroscopy and image analysis to the study of viruses and viral proteins. (gla.ac.uk)

The two other viruses within the Nodaviridae are Noramura virus and Flock House virus. (wikipedia.org)

Many, although not all, emerging infectious diseases are caused by viruses, and these frequently emerge from nonhuman host reservoirs ( 1 - 3 ). (cdc.gov)
Increasing amounts of data indicate that bats harbor a higher viral diversity relative to other mammalian orders, and they have been recognized as potential reservoirs for pathogenic viruses, such as the Hendra, Nipah, Marburg, and SARS-CoV viruses. (mdpi.com)

Viruses attain this level of economy by assembling their capsids in a highly symmetrical manner making these structures not only scientifically interesting but also beautiful. (gla.ac.uk)

Many new and emerging RNA and DNA viruses are zoonotic or have zoonotic origins in an animal reservoir that is usually mammalian and sometimes avian. (cdc.gov)

Not all zoonotic viruses are transmissible (directly or by an arthropod vector) between human hosts. (cdc.gov)
BHV, BAV, SWBV and TIBV were isolated from biting midges, suggesting that midges are the major arthropod vector for these viruses. (wikimili.com)

To release, the virus causes lysis of the host cell from which copies of newly made virus are released. (wikipedia.org)

A series of recent emerging infectious disease outbreaks, including the 2014 Ebola virus disease (EVD) epidemic in West Africa and the continuing Zika virus disease epidemic in the Americas, have underlined the need for better understanding of which kinds of pathogens are most likely to emerge and cause disease in human populations. (cdc.gov)

There is no evidence of human exposure or any disease associated with the virus. (wikimili.com)
TIBV is an orphan virus and not associated with any disease. (wikimili.com)

This paper was prepared in response to the need for clear communication regarding the risk of transmission of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 in humans and the general societal concern of potential contamination of aquatic animals used as food or their products with the virus. (who.int)

Typically, Nodaviridae will form an invagination within the membrane of the host cell mitochondria where it will prepare to replicate. (wikipedia.org)

Tibrovirus virions are enveloped, but only the morphology of Tibrogargan virus and Sweetwater branch virus have been observed by electron microscopy. (wikimili.com)

Another group of viruses called bidnaviruses appear to be descended from parvoviruses. (mdwiki.org)

These viruses are priorities for surveillance because relatively minor changes in their epidemiologies can potentially lead to major changes in the threat they pose to public health. (cdc.gov)
This graph shows the total number of publications written about "Nodaviridae" by people in UAMS Profiles by year, and whether "Nodaviridae" was a major or minor topic of these publications. (uams.edu)
Viruses, far from being just parasites affecting hosts' fitness, are major players in any microbial ecosystem. (mdpi.com)

The establishment of these capabilities within a dedicated virus research laboratory gives us an exciting opportunity to visualise the process of virus infection at cellular scale and macromolecular resolution. (gla.ac.uk)

Aquatic food animals and their products, like any other surface, may potential y become contaminated with SARS-CoV-2, especial y when handled by people who are infected with the virus. (who.int)
Below are the most recent publications written about "Nodaviridae" by people in Profiles over the past ten years. (uams.edu)

Click on the PDF icon to the left to view a copy of this virus entry in PDF format. (cdc.gov)

The structural components of viruses represent an intriguing area of study for the structural biologist. (gla.ac.uk)

Virus penetrates into the host cell. (expasy.org)

Organisms2

Diseases1

Genus6

Betanodavirus1

Nervous necrosis virus1

Insect Viruses1

Family10

19841

SsRNA1

Genome8

Species4

Cytoplasm2

Capsid1

Nodamura2

Descriptor1

Replication4

Genomes2

Invertebrate1

Larvae3

Icosahedral3

TAXONOMY1

Recombinant3

Human viruses1

Infect4

Protein1

Proteins2

Flock1

Reservoirs2

Capsids1

Mammalian1

Arthropod vector2

Lysis1

Pathogens1

Disease2

Humans1

Form1

Electron1

Group1

Major3

Cellular1

People2

Entry1

Structural1

Host1