• irritates eyes, respiratory tract and mucous membranes. (ihcworld.com)
  • Donovanosis is a bacterial infection of the skin and mucous membranes in the genital region. (health.mil)
  • Hydrogen - chloride is irritating in all concentrations to eyes and mucous membranes, with pathological changes occurring in bronchial and tracheal epithelium. (cdc.gov)
  • VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. (bvsalud.org)
  • To improve the comprehensibility of electron micrographs, endothelial cells (E) have been transparently highlighted in BD-3 Protein Rat yellow, though basement membranes were transparently highlighted in red. (c-mycinhibitor.com)
  • Further analysis by in situ hybridization revealed that CysLT(2) mRNA was expressed in myocytes, fibroblasts, and vascular smooth muscle cells, but not in endothelial cells. (nih.gov)
  • Convincing data have been presented to show that production of reactive oxygen species (ROS) occurs in nonphagocytic cells, including endothelial cells ( 8 ), vascular smooth muscle cells ( 9 ), and aortic adventitial fibroblasts ( 10 ), and superoxide anion has a variety of biological functions that accompany induction of gene expression ( 11 ), cellular proliferation ( 12 ), apoptosis ( 13 , 14 ), and hypertrophy ( 15 ). (diabetesjournals.org)
  • Similarly, sEng is a truncated form of receptor for two subtypes of transforming growth factor beta (TGF β ) specifically, TGF β 1 and TGF β 2 which are highly expressed by vascular endothelial cells and syncytiotrophoblasts. (hindawi.com)
  • However, a large proportion of cases do not occur in the context of any associated disease or known history and therefore are classified as idiopathic epimacular membranes (IEMM). (medscape.com)
  • Charles S. Epimacular Membranes. (medscape.com)
  • all of which pertain to clinico-anatomic descriptions of pathologic findings produced by epiretinal membranes of varying severity and differing morphologic characteristics. (medscape.com)
  • Epiretinal membranes can be associated with various ocular conditions, such as posterior vitreous detachments (PVD), retinal tears, retinal detachments , retinal vascular occlusive diseases, ocular inflammatory diseases, and vitreous hemorrhage . (medscape.com)
  • Idiopathic and postdetachment membranes are the most common epiretinal membranes and, as such, are the focus of this article. (medscape.com)
  • Epiretinal membranes are avascular, fibrocellular membranes that proliferate on the surface of the retina and can lead to varying degrees of visual impairment. (medscape.com)
  • Modern vitrectomy specimens have shown that epiretinal membranes comprise glial cells, retinal pigment epithelial cells, macrophages, fibrocytes, and collagen cells. (medscape.com)
  • Kofod M, Christensen UC, la Cour M. Deferral of surgery for epiretinal membranes: Is it safe? (medscape.com)
  • CoQ10 works as a potent free radical scavenger in cell membranes, as well as within blood vessels. (muscleandstrength.com)
  • It is characterized by the prominence of skin blood vessels, such as vascular spiders. (bvsalud.org)
  • During inflammation polymorphonuclear neutrophils (PMNs) traverse venular walls, composed of the endothelium, pericyte sheath and vascular basement membrane. (tamu.edu)
  • Vascular complications are responsible for the excess mortality associated with diabetes ( 1 ), and impaired endothelium-dependent vasodilation has been described in humans and in animal models of the disease ( 2 - 6 ). (diabetesjournals.org)
  • PSMA is a cell surface glycoprotein receptor present on tumor vascular endothelium of many types of cancer [6, 7]. (aiche.org)
  • Cations stimulated aortic muscle membrane aggregation with increasing potency according to their effective charge, e.g. (mcmaster.ca)
  • A, B) Aortic computed-tomography angiogram (A) and 3-dimensional reconstruction (B) show the periprosthetic collection and vascular leak (arrows). (cdc.gov)
  • A paediatric dermatologist , paediatrician, vascular specialist or surgeon should assess significant infantile capillary malformations or infantile haemangiomas , especially when large, symptomatic (especially when ulcerated), located on the head and neck or close to eye, nose or mouth. (dermnetnz.org)
  • G polymorphism is associated with organ vascular malformations in hereditary hemorrhagic telangiectasia patients with ENG mutations, but not in patients with ACVRL1 mutations. (cdc.gov)
  • Association of common candidate variants with vascular malformations and intracranial hemorrhage in hereditary hemorrhagic telangiectasia. (cdc.gov)
  • The PCA-derived vascular biomarker cluster was positively associated with linoleic acid, n-6PUFA:n-3PUFA ratio and inversely associated with EPA.ConclusionSpecific erythrocyte membrane fatty acid compositions are associated with impaired vascular health and IR in adults with T1D. (swan.ac.uk)
  • The North American interventional cardiology and peripheral vascular devices market is consolidated with five key players that contributed to a collective share of 91% in 2013. (marketsandmarkets.com)
  • The increasing volume of peripheral intervention and DVT/PE treatment procedures are expected to lure new entrants in the North American interventional cardiology and peripheral vascular devices market in the coming years. (marketsandmarkets.com)
  • The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. (nih.gov)
  • The most widely studied serum markers for PE, to date, are vascular endothelial growth factor (VEGF) and placental growth factor (PlGF). (hindawi.com)
  • Here, we review current knowledge how proteases act on platelet receptors and the platelet membrane surface. (frontiersin.org)
  • Angiogenic factors and their receptors are important regulators of placental vascular development [ 13 ]. (hindawi.com)
  • Very dense epiretinal membrane with associated macular distortion. (medscape.com)
  • To evaluate expression of proangiogenic matrix metalloproteinases (MMP) 2 and 9 at distinct intervals after verteporfin photodynamic therapy (PDT) in human choroidal neovascular membranes (CNV) secondary to age-related macular degeneration (AMD). (bmj.com)
  • OCT has been routinely used in measuring retinal thickness for the evaluation of ME caused by diseases such as age-related macular degeneration, diabetic retinopathy, hereditary retinal degenerations, retinal vein occlusion, after cataract surgery, epiretinal membrane (ERM) and uveitis. (bmj.com)
  • Bovey EH, Uffer S. Tearing and folding of the retinal internal limiting membrane associated with macular epiretinal membrane. (medscape.com)
  • Karacorlu M, Ozdemir H, Senturk F, Karacorlu SA, Uysal O. Correlation of retinal sensitivity with visual acuity and macular thickness in eyes with idiopathic epimacular membrane. (medscape.com)
  • Surgical treatment of lamellar macular hole associated with epimacular membrane. (medscape.com)
  • Macular pucker: to peel or not to peel the internal limiting membrane? (medscape.com)
  • C) Intraoperative view shows the graft exposure and false necrotic membranes. (cdc.gov)
  • Liposomes were prepared by hydrating a thin lipid film with the desired aqueous phase buffer, incubating at 55° Celsius for 2 hours, and extruding the resultant suspension through 100 nm -pore polycarbonate membranes to generate unilamellar vesicles. (aiche.org)
  • Earlier reports proposed that glial cells (primarily fibrous astrocytes) from the inner layers of the neurosensory retina proliferated through breaks in the internal limiting membrane (ILM) produced after a retinal tear or a posterior vitreous detachment. (medscape.com)
  • Liu H, Zuo S, Ding C, Dai X, Zhu X. Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis. (medscape.com)
  • Recognized worldwide, the Johns Hopkins Heart and Vascular Institute provides comprehensive care of the highest quality, ensuring that patients receive the most advanced treatments known to medicine. (hopkinsmedicine.org)
  • At the Johns Hopkins Heart and Vascular Institute, cardiac specialists swiftly translate laboratory discoveries into new treatments, with the ultimate goal of saving more lives from heart disease, the leading cause of death in the United States. (hopkinsmedicine.org)
  • Whether you are interested in a preventive heart screening, a consultation, or treatment for an existing cardiovascular condition, rest assured that you will receive the highest quality of care from our heart and vascular physicians. (ohiohealth.com)
  • Years of scientific research have shown that CoQ10 helps to maintain a healthy heart and vascular system. (muscleandstrength.com)
  • In ischemia-affected regions, the vascular Cx43 expression seems to become condensed in vessels displaying FITC-albumin extravasation (arrow heads). (c-mycinhibitor.com)
  • Corkscrew vascular loops and feeder vessels are seen. (medscape.com)
  • CNV without previous therapy disclosed MMP-2, MMP-9 in RPE-Bruch's membrane, vessels and stroma in different intensities. (bmj.com)
  • Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis. (harvard.edu)
  • They regulate the excitability of cells and contribute to their resting membrane potential [ 1 , 2 ]. (ersjournals.com)
  • Vascular sheath between the hyaloid membrane and the vitreous humour. (dictionary.com)
  • Taking our in vitro results back into mouse models, we present evidence that pericyte relaxation contributes to the opening of the gaps between pericytes and to the enlargement of the LERs in the vascular BM, facilitating PMN extravasation. (tamu.edu)
  • 1999) Identification of immunoreactive tissue prokallikrein on the surface membrane of human neutrophils. (nature.com)
  • Upon prolonged high intracellular rises in Ca 2+ , platelets develop a procoagulant phenotype that is characterized by the surface membrane exposure of phosphatidylserine and by the inactivation of integrin α IIb β 3 (procoagulant platelet population) ( 5 ). (frontiersin.org)
  • Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress and endothelial dysfunction. (hindawi.com)
  • The atherosclerotic process is accelerated by a myriad of factors, such as the release of inflammatory chemokines and cytokines, the generation of reactive oxygen species (ROS), growth factors, and the proliferation of vascular smooth muscle cells. (hindawi.com)
  • The growth in this market can be attributed to a large number of approvals for vascular closure devices, high prevalence of cardiovascular diseases, increasing prevalence of obesity, increasing focus of market players on large-bore vascular closure devices, growing geriatric population, favorable reimbursement scenario for interventional radiology procedures, and rising focus on effective blood loss management in patients during surgeries. (marketsandmarkets.com)
  • Cardiovascular (CV) risk factors such as hypercholesterolemia, hyperglycaemia, obesity, hypertension, smoking, and aging promote vascular inflammation and endothelial activation [ 7 - 9 ]. (hindawi.com)
  • This membrane has now been patented, and Ferrari is working with fellow researchers at the Wyss Zurich research center, the University of Zurich, and the German Center of Cardiovascular Research in Berlin to make it market ready for use in patients. (medicaldesignbriefs.com)
  • Controlling these factors reduces the risk of acute vascular complications and death from CVD [ 1 , 7 ]. (hindawi.com)
  • Superoxide anion can modulate vascular smooth muscle tone and is potentially involved in diabetic vascular complications. (diabetesjournals.org)
  • Development of novel therapeutic approaches to bolster kinin activity in the vascular wall and in specific compartments in the kidney might be a highly effective strategy for the treatment of hypertension and its complications, including cardiac hypertrophy and renal failure. (nature.com)
  • Idiopathic Epiretinal Membrane and Vitreomacular Traction Preferred Practice Pattern(®) Guidelines. (medscape.com)
  • Long-term anatomical and functional results in patients undergoing observation for idiopathic nontractional epiretinal membrane. (medscape.com)
  • Hosoda Y, Ooto S, Hangai M, Oishi A, Yoshimura N. Foveal Photoreceptor Deformation as a Significant Predictor of Postoperative Visual Outcome in Idiopathic Epiretinal Membrane Surgery. (medscape.com)
  • Surgical removal of idiopathic epiretinal membrane with or without the assistance of indocyanine green: a randomised controlled clinical trial. (medscape.com)
  • Terumo Corporation (Japan) is a leading player in the vascular closure devices market, with a market share of 33.4% in 2020. (marketsandmarkets.com)
  • Abbott (US) accounted for the high share of the vascular closure devices market in 2020. (marketsandmarkets.com)
  • Cardinal Health (US) held the third position in the vascular closure devices market in 2020. (marketsandmarkets.com)
  • A fibrous membrane surface impedes this process," says Francesco Robotti, lead author of the study and a scientist in ETH Professor Poulikakos's group. (medicaldesignbriefs.com)
  • The pathogenesis of arterial hypertension often involves a rise in systemic vascular resistance (vasoconstriction and vascular remodeling) and impairment of salt excretion in the kidney (inappropriate salt retention despite elevated blood pressure). (nature.com)
  • Pulmonary vascular effects of prostaglandin D2 but not its systemic vascular or airway effects are mediated through thromboxane receptor activation. (hopkinsmedicine.org)
  • We provide a comprehensive overview of the proteases acting on the platelet membrane. (frontiersin.org)
  • 4-5 Early lesions are small, painless nodules that grow into characteristic "beefy red" highly vascular ulcers and progressively expand. (health.mil)
  • The terminology of vascular conditions can be confusing, with several lesions being incorrectly named or classified. (dermnetnz.org)
  • In the Sheikh Zayed Tower at The Johns Hopkins Hospital, specialists in every branch of cardiac care - cardiology , cardiac surgery , vascular medicine , and radiology - work collaboratively in a hospital setting designed to foster innovative treatments and accelerate the science of medicine. (hopkinsmedicine.org)
  • Rahman R, Stephenson J. Early surgery for epiretinal membrane preserves more vision for patients. (medscape.com)
  • Phosphatidylserine-exposing platelets, usually located around a thrombus, provide a negatively charged membrane surface, which supports coagulation factor binding and the formation of tenase and prothrombinase complexes ( 6 , 7 ). (frontiersin.org)
  • Upon activation, platelets release plasma-membrane derived microparticles (PMPs) exposing phosphatidylserine (PS) on their surface. (lu.se)
  • When the pH is lowered below 6.0, membrane aggregation progressively increased with a concomitant decrease in cation-induced aggregation. (mcmaster.ca)
  • Scientists have developed a special protective membrane made of cellulose that significantly reduces the buildup of fibrotic tissue around cardiac pacemaker implants, as reported in a recent issue of the journal Biomaterials. (medicaldesignbriefs.com)
  • 1 The protective membrane could greatly simplify surgical procedures for patients with cardiac pacemakers. (medicaldesignbriefs.com)
  • The objective of this study is to design a new class of liposomes that can target tumor vasculature via Prostate-Specific Membrane Antigen (PSMA) and rapidly and extensively release therapeutic agents intracellularly by using the pH-sensitive peptide GALA conjugated to lipid moieties to destabilize the integrity of intracellular endosomes and achieve better tumor killing outcomes. (aiche.org)
  • Alveolar epithelial changes and vascular injury also occur. (cdc.gov)
  • Finally, vitreous hemorrhage, inflammation, or both associated with a PVD also may stimulate epiretinal membrane formation. (medscape.com)
  • [ 2 ] They hypothesize that the presence of ILM tears and folds are more likely when the epiretinal membrane forms prior to a posterior vitreous detachment, resulting in the subsequent cleavage plane being between the ILM and the inner retina rather than at the ILM surface. (medscape.com)
  • the delicate, pellucid, and nearly structureless membrane enclosing the vitreous humor of the eye. (dictionary.com)
  • An immediate effect of alcohol ingestion is vasodilation in some vascular beds. (medscape.com)
  • PurposeThe aim of this study was to assess the relationship between specific erythrocyte fatty acids levels and vascular health in type 1 diabetes (T1D) with and without insulin resistance (IR).MethodsWe analysed baseline pretreatment data in a subset of 23 patients with T1D from a previously publis. (swan.ac.uk)
  • PurposeThe aim of this study was to assess the relationship between specific erythrocyte fatty acids levels and vascular health in type 1 diabetes (T1D) with and without insulin resistance (IR).MethodsWe analysed baseline pretreatment data in a subset of 23 patients with T1D from a previously published randomised controlled trial consisting of comprehensive erythrocyte-derived fatty acid profiles and a panel of inflammation-associated endothelial markers. (swan.ac.uk)
  • Affects nervous system and may cause vascular system disorders. (ihcworld.com)
  • Our results indicate that cation-induced membrane aggregation can also be used to isolate a plasma membrane-enriched fraction from vascular smooth muscle. (mcmaster.ca)
  • Here, we report that in AD patients and two mouse models of AD, overexpression of serum response factor (SRF) and myocardin (MYOCD) in cerebral vascular smooth muscle cells (VSMCs) generates an Aβ non-clearing VSMC phenotype through transactivation of sterol regulatory element binding protein-2, which downregulates low density lipoprotein receptor-related protein-1, a key Aβ clearance receptor. (nature.com)
  • This gene subfamily is constitutively active at physiological resting membrane potentials in excitable cells, including smooth muscle cells, and has been particularly linked to the human pulmonary circulation. (ersjournals.com)
  • This article is a review of exciting, recently generated genetic, biochemical and clinical data from studies that have examined the importance of the tissue kallikrein-kinin system in protection from hypertension, vascular remodeling and renal fibrosis. (nature.com)
  • An epiretinal membrane (ERM) is a collection of collagenous cells that occurs on the inner surface of the central retina. (medscape.com)
  • These cells, once in contact and attached to the retina, may proliferate and form sheets of membranes over the surface of the retina. (medscape.com)
  • The source of the cells producing these membranes has been the source of great debate. (medscape.com)
  • These cells are found in varying proportions in accordance with the etiology of the membrane. (medscape.com)
  • Membranes associated with retinal breaks, previous retinal detachments, or cryopexy are composed mainly of dispersed RPE cells, while cells of glial origin predominate in the IEMM. (medscape.com)
  • PVD can lead to retinal breaks that may liberate RPE cells that initiate membrane formation. (medscape.com)
  • A sagittal section of this stage is shown in figure 2 A . The foregut is here more inclosed, and the notochord, nt , having separated from the entoderm, en , is seen as a distinct layer of cells extending from the foregut to the blastopore. (gutenberg.org)
  • The lens capsule arises at about the same period as the hyaloid membrane , and is a product of the cells of the lens. (dictionary.com)
  • Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. (harvard.edu)
  • During medical school, his research focused on the vascular morphology and mural cells of the murine germinal matrix. (rochester.edu)
  • They span the membrane of cells, allowing the selective permeation of K + ions from one side of the membrane to the other, usually from the inside of the cell to the outside. (ersjournals.com)
  • The patterns of aggregation of microsomal membranes and further purified plasma membranes were almost identical whereas the aggregation of the heterogeneous mitochondrial membrane-enriched fraction was distinctly different in the initial rate of aggregation, its pH dependence, and metal ion concentration dependence. (mcmaster.ca)
  • Studies suggest that healthy red blood cell membrane omega-3 fatty acid concentration is associated with emotional well-being. (vitacost.com)
  • In line with these results, studies using various enzyme inhibitors, such as DPI, allopurinol, rotenone, N G -monomethyl- l -arginine, and indomethacin, suggest that the predominant source of superoxide anion in vascular particulate fraction is NADH-dependent membrane-bound oxidase. (diabetesjournals.org)
  • PPC is a phospholipid, and an essential nutrient found in certain foods and in every cell membrane in your body. (betterlife.com)
  • By supporting vascular health, fish oils promote oxygen and nutrient delivery to the brain. (vitacost.com)
  • Just as importantly, the membrane did what it was supposed to: the fibrotic tissue that formed around it was, on average, only a third as thick as the tissue that formed around the unencapsulated pacemakers. (medicaldesignbriefs.com)
  • Influence of membrane composition on the enhancement of factor VIIa/tissue factor activity by magnesium ions. (harvard.edu)
  • A Comparison of Intraoperative Dexamethasone Intravitreal Implant and Triamcinolone Acetonide Used During Vitrectomy and Epiretinal Membrane Peeling: A Case Control Study. (medscape.com)
  • while, in 2012, Abbott introduced Absolute Pro, a vascular self-expanding stent system, for treatment of the iliac artery disease. (marketsandmarkets.com)
  • The tree's vascular system draws the water up through the trunk and distributes it to the leaves. (treehelp.com)