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  • Mumps
  • Before the autism-related controversy started in 1998, some concern had already arisen about the safety of the MMR vaccine due to side effects associated with the Urabe mumps strain, including rare adverse events of aseptic meningitis, a transient mild form of viral meningitis. (wikipedia.org)
  • A late-1980s trial in Britain of a form of the MMR vaccine containing the Urabe mumps strain produced three cases of probably associated febrile convulsions per 1,000 vaccinations. (wikipedia.org)
  • With no such risk seen in vaccines using the Jeryl Lynn mumps strain, the UK NHS withdrew two of the three MMR vaccines then available (Immravax, made by Merieux UK, and Pluserix, made by SmithKline Beecham) in favor of Merck Sharp and Dohme's MMR II brand, based on the Jeryl Lynn strain. (wikipedia.org)
  • Some forms of meningitis are preventable by immunization with the meningococcal, mumps, pneumococcal, and Hib vaccines. (wikipedia.org)
  • chicken pox vaccine
  • Individuals should not receive ProQuad without first consulting their doctor if there is a history of a life-threatening allergic reaction to gelatin, eggs, the antibiotic neomycin, or a previous MMR or chicken pox vaccine. (wikipedia.org)
  • hepatitis
  • Previous studies estimated that vaccinating high-risk heterosexuals (HRH) with combination hepatitis A/B vaccine was a cost-effective alternative to vaccinating HRH against hepatitis B alone. (rti.org)
  • immunity
  • WASHINGTON - New research suggests a one-two punch could help battle polio in some of the world's most remote and strife-torn regions: Giving a single vaccine shot to children who've already swallowed drops of an oral polio vaccine greatly boosted their immunity. (recordonline.com)
  • The shots acted as a better booster for the children's intestinal immunity than giving them yet more vaccine drops - and those youngsters shed far less virus, key to cutting transmission in an outbreak, Jafari's team reported. (recordonline.com)
  • therapeutic
  • Demonstrating that this therapeutic vaccine increased the complete response rate by 15% in this trial, without adding significant toxicities, represents an important scientific and medical advance. (marketwired.com)
  • The late-breaker poster (LB15) titled, "GI-5005 Therapeutic Vaccine Plus Peg-IFN/Ribavirin Improves End of Treatment Response at 48 Weeks Versus Peg-IFN/Ribavirin in Naive Genotype 1 Chronic HCV Patients" will be presented by Dr. McHutchison at the AASLD Meeting today from 1:00 - 2:30 p.m. in the Hynes Exhibit Hall C at the John B. Hynes Convention Center in Boston. (marketwired.com)
  • Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines against cancer are being investigated). (wikipedia.org)
  • guinea pigs
  • The peptide vaccine induced anti-A β antibodies in cynomolgus monkeys and guinea pigs without chemical adjuvants, and excessive immune responses were not observed. (hindawi.com)
  • The peptide vaccine could induce a similar binding profile of anti-A β antibodies in cynomolgus monkeys and guinea pigs. (hindawi.com)
  • The class of proteins that includes Na-ASP-2, ASPs, are promising vaccine candidates based on previous vaccine studies in sheep, guinea pigs, cattle, and mice, which have demonstrated inhibition of hookworm larval migration. (wikipedia.org)
  • polio
  • Oral polio vaccine has played a critical role in the nearly three-decade effort to eradicate the paralyzing disease, as health workers have gone house-to-house, to refugee camps and to roadside checkpoints delivering the drops. (recordonline.com)
  • The United States and other wealthy countries have switched back to using only injected polio vaccine, which is made of "inactivated" or killed virus, for routine childhood immunizations after eradicating the disease within their borders. (recordonline.com)
  • That's because the oral vaccine contains weakened live virus that children can shed in their stools, which on very rare occasions can trigger a vaccine-caused case of polio. (recordonline.com)
  • Health workers used both injected and oral vaccine as they sought to immunize 126,000 young children living in Somali refugee camps and nearby areas who were at risk from a polio outbreak spilling over the Somalia-Kenya border. (recordonline.com)
  • antibodies
  • When the M. hyo component is grown, it likely contains PCV antibodies, which can affect the potency of the PCV fraction when the two fractions are combined. (pigprogress.net)
  • some individuals are "non-responders" to certain vaccines, meaning that they do not generate antibodies even after being vaccinated correctly. (wikipedia.org)
  • widely
  • However, Hib remains a major cause of lower respiratory tract infections in infants and children in developing countries where the vaccine is not widely used. (wikipedia.org)
  • The most widely administered pentavalent vaccine globally - Quinvaxem has been administered to 400 million children as of 2013. (wikipedia.org)
  • hypersensitivity
  • Conducted in 1999, this review found no evidence of harm from the use of thimerosal as a vaccine preservative, other than local hypersensitivity reactions. (wikipedia.org)
  • strain
  • In 2013, in addition to the existing vaccine against avian influenza (strain H5N1), Microgen initiated the development of pre-pandemic "Chinese flu" vaccine (strain H7N9). (wikipedia.org)
  • infections
  • Unencapsulated H. influenzae strains are unaffected by the Hib vaccine and cause ear infections (otitis media), eye infections (conjunctivitis), and sinusitis in children, and are associated with pneumonia. (wikipedia.org)
  • The World Health Organization (WHO) reports that licensed vaccines are currently available for twenty-five different preventable infections. (wikipedia.org)
  • humans
  • Though both DNA-HIV-PT123 and AIDSVAX®B/E and the combination of the two vaccines have been evaluated in humans and have shown to be safe and well tolerated, this is the first time the combination regimen is being evaluated in HIV-1 uninfected African populations with and without S. mansoni. (clinicaltrials.gov)
  • No effective vaccine for the disease in humans has yet been developed. (wikipedia.org)
  • a combined vaccine for humans that would provide more complete protection. (wikipedia.org)
  • clinical
  • Examples of antigenic targets of hookworm vaccines currently in clinical trials include Na-ASP-2 from N. americanus, Ac-APR-1 from Ancylostoma caninum, Ac'-APR-1 and Na-GST-1/Alhydroge. (wikipedia.org)
  • combination
  • The secondary objective of the trial is to evaluate the effect of S. mansoni infection on the immunogenicity of the combination of DNA-HIV-PT123 and AIDSVAX® B/E vaccine regimen. (clinicaltrials.gov)
  • A combination therapy of multi-peptide vaccine with CRT can successfully be performed with satisfactory levels of safety, and application of this combination therapy may be an effective treatment for patients with unresectable ESCC. (biomedcentral.com)
  • With this M. hyo fraction, we can now produce a one-bottle combination vaccine. (pigprogress.net)
  • incidence
  • Due to routine use of the Hib conjugate vaccine in the U.S. since 1990, the incidence of invasive Hib disease has decreased to 1.3/100,000 in children. (wikipedia.org)
  • Autism incidence rates increased steadily even after thiomersal was removed from childhood vaccines. (wikipedia.org)
  • typically
  • The MMRV vaccine is typically given to children between 1 and 2 years of age. (wikipedia.org)
  • A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. (wikipedia.org)
  • Cancer
  • Jacinto Convit García (11 September 1913 - 12 May 2014) was a Venezuelan physician and scientist, known for developing a vaccine to fight leprosy and his studies to cure different types of cancer. (wikipedia.org)
  • On June 7, 2010, a Venezuelan newspaper incorrectly announced the successful development by Convit of a new cancer vaccine intended to prevent colon, stomach and breast cancer. (wikipedia.org)
  • Venezuela's National Institute of Biomedicine soon published a note clarifying that they have been working for the previous three years on a vaccine against cancer and it is still in development. (wikipedia.org)
  • disease
  • Most regional countries however, are unable to produce their own vaccine against the disease. (devex.com)
  • Reviews of the evidence by the Centers for Disease Control and Prevention, the American Academy of Pediatrics, the Institute of Medicine of the US National Academy of Sciences, the UK National Health Service, and the Cochrane Library all found no link between the MMR vaccine and autism. (wikipedia.org)
  • However, these drugs only eliminate existing adult parasites and re-infection can occur soon after treatment, school-based de-worming efforts do not treat adults or pre-school children, and concerns exist about drug resistance developing in hookworms against the commonly used treatments, thus a vaccine against hookworm disease is sought to provide more permanent resistance to infection. (wikipedia.org)
  • According to a ProMED article, disease in sheep has been controlled in the UK by a vaccine (ATCvet code: QI04AA01), originally developed by Scotland's Moredun Research Institute by Prof John Russell Greig. (wikipedia.org)
  • In 2009, however, a shortage of vaccine combined with an increase in the number of ticks found in sheep pasture areas cause an increased risk of this disease. (wikipedia.org)
  • It has also been criticised for harassing the parents of a victim of vaccine-preventable disease, and for promoting the false idea that shaken baby syndrome is actually vaccine injury. (wikipedia.org)
  • The cause of the disease was determined in 1884 by Antonio Carle and Giorgio Rattone at the University of Turin, with a vaccine being developed in 1924. (wikipedia.org)
  • WHO's
  • Produced by Panacea Biotec, Easyfive was removed from the WHO's list of pre-approved and prequalified vaccines in mid-2011. (wikipedia.org)
  • years
  • The Kitasato Institute Research Center for Biologicals (current Kitasato Daiichi Sankyo Vaccine) and JICA offered technical assistance to Vietnam's public corporation Center for Research and Production of Vaccines and Biologicals (POLYVAC) to produce the measles vaccine for four years between March 2006 and March 2010. (devex.com)
  • The campaign aims to vaccinate almost 5 million children between 9 and 15 years of age with the combined MR vaccine during this week. (unmultimedia.org)
  • effective
  • That's why we let science lead the way in developing an effective and safe vaccine all in one convenient bottle. (pigprogress.net)
  • The combined vaccine was tested worldwide, but was not more effective than regular BCG. (wikipedia.org)
  • The government of Brazil, where hookworm is still endemic in some poorer areas, has promised to manufacture a vaccine if one can be proven effective. (wikipedia.org)
  • Vaccines have historically been the most effective means to fight and eradicate infectious diseases. (wikipedia.org)
  • investigation
  • An investigation by journalist Brian Deer found that Andrew Wakefield, the author of the original research paper linking the vaccine to autism, had multiple undeclared conflicts of interest, had manipulated evidence, and had broken other ethical codes. (wikipedia.org)
  • After the incidents in Vietnam, a joint statement was released by WHO and UNICEF confirming the safety of Quinvaxem and approval for its continued use as a pentavalent vaccine, after careful investigation, it was found that the fatalities reported in Vietnam were either coincidental health problems related in time but not related to the use of Quinvaxem, or cases for which the information available does not allow for a definite conclusion. (wikipedia.org)
  • generate
  • Therefore, there is a potential that helminth infected populations may not generate the desired immune responses to vaccines designed to drive Th1-type and cytotoxic T-cell responses. (clinicaltrials.gov)
  • vaccinations
  • Several controversial claims have been made with regard to autism and vaccinations, leading notably to the MMR vaccine controversy, the thiomersal controversy, and the theory of vaccine overload. (wikipedia.org)
  • adverse
  • Concerns about adverse reactions to the vaccine were raised by American and Canadian authorities based on reports from Japan linking Urabe MMR with meningoencephalitis. (wikipedia.org)
  • children
  • The children had previously received oral vaccine. (recordonline.com)
  • In the wake of the measles outbreaks, which occurred in England in 1992, and on the basis of analyses of seroepidemiological data combined with mathematical modeling, British Health authorities predicted a major resurgence of measles in school-age children. (wikipedia.org)
  • It is recommended that aspirin or aspirin containing products be avoided for at least six weeks after receiving ProQuad vaccine (aspirin is not recommended in children under 16 in any case). (wikipedia.org)
  • Since the vaccine was first used in 2007, at least 63 children have died after being vaccinated. (wikipedia.org)
  • Microgen started testing a new anti-tick vaccine for children. (wikipedia.org)