Ultramicroscopy electron energy loss spectroscopy microscopy electron. Medical search. Frequent questions

At the Fritz-Haber-Institute, he especially promoted the work of his staff in the areas of Quantitative Electron Microscopy (M. van Heel), cryo-electron microscopy with a supra-conducting lens (F. Zemlin), photoelectron microscopy (W. Engel), and electron energy loss spectroscopy (D. Krahl). (wikipedia.org)
In life sciences, the CCOR is especially advantageous for cryo electron microscopy (cryoEM) and cryo tomography where intense inelastic scattering occurs due to high sample thickness and high sample tilt. (ceos-gmbh.de)

Fast and sensitive, this hybrid-pixel electron detector enables advanced data collection in EELS and 4D STEM. (dectris.com)
ELA hybrid-pixel detector is specifically optimized for Electron Energy Loss Spectroscopy (EELS) and Four-Dimensional Scanning Transmission Electron Microscopy (4D STEM). (dectris.com)
CEOS CEFID is very attractive for Electron Energy Loss Spectroscopy (EELS) applications, as its small non-isochromaticity (NI), as well as its long-term stability and reliable reproducibility of optical alignments, guarantees an excellent energy resolution. (dectris.com)
Although the mutual repulsion of electrons within the pulses still limit spatial, temporal and energy resolution, combined imaging, diffraction and EELS studies turned out to be possible so that a comprehensive picture of the reaction kinetics in nanocrystals can be obtained. (ipcms.fr)
The combination of imaging, electron diffraction and EELS gives unprecedented insight into the dynamics of the reaction. (ipcms.fr)
As an example of a complex electron microscopy data analysis problem that can be easily addressed with SAMFire, Figure 2 shows a single spectrum and the result of EELS elemental and bonding quantification by curve fitting from a tilt-series of spectrum-images of a mixed phase nanoparticle. (emc-proceedings.com)
Therefore, in materials science the CCOR opens up new applications in the context of energy-filtered TEM imaging (EFTEM) and electron energy loss spectroscopy (EELS), and is especially useful for investigations on thick object structures. (ceos-gmbh.de)
Improvements in instrumentation for energy-dispersive X-ray microanalysis (EDX) and electron energy-loss spectroscopy (EELS) have underlined the need for suitable standards for measuring performance. (cambridge.org)
Electron energy loss spectroscopy (EELS) measurements were made in a Carl Zeiss LEO-922 TEM equipped with an Omega filter. (springer.com)
Low acceleration voltages have several important advantages for spectroscopic applications, in particular electron energy-loss spectroscopy (EELS) and energy-filtered TEM. (salve-project.de)

My research emphasizes two main areas: i) the application of in-situ high-resolution and analytical transmission electron microscope techniques to study mechanisms of phase transformations and the structure and properties of interphase boundaries at the atomic level, and ii) the use of valence electron energy-loss spectroscopy (plasmons) to understand and determine the physical properties of nanoscale materials and interfaces. (virginia.edu)

As a research assistant at the Vienna University of Technology, she was one of the main participant to the CHIRALTEM project dealing with the measurement of magnetic circular dichroism in the electron microscope. (epfl.ch)
Here we demonstrate the use of nanofabricated grating holograms to diffract and shape electrons in a scanning electron microscope. (bvsalud.org)
a) Atomic resolution phase contrast image of YAIO_3:Ce (YAP), recorded in the chromatic and spherical aberration-corrected PICO electron microscope with CCOR at 200 kV. (ceos-gmbh.de)
Tilt series for tomography of a whole macrophage cell, imaged with a chromatically and spherically corrected transmission electron microscope at 300 kV, with semi aperture 10° and pixel size 4.53 nm (TFS Titan 80-300 „PICO", PICO project, Er-C, Jülich, Germany). (ceos-gmbh.de)
Secondary ion mass spectroscopy microscopes can provide 50-nm spatial resolution mapping of molecular masses, but because the specimen is eroded in the microscope, one can examine a microscopic feature only once. (nationalacademies.org)
The short-range order of individual fractal-like amorphous carbon nanotips was investigated by means of energy-filtered electron diffraction in a transmission electron microscope (TEM). (springer.com)
However, an advantage that amorphous carbon (a-C) nanotips have over carbon nanotubes is that when a-C nanotips are synthesized using the electron beam-induced deposition method with a transmission electron microscope (TEM-EBID) their growth process can be followed in real-time and the nanostructures can be grown at preferred positions by controlling the electron beam [ 11 ]. (springer.com)
Electron microscope loading and in situ nanoindentation of water ice at cryogenic temperatures. (mpie.de)
High resolution structure determination by electron cryo-microscopy (cryoEM) and Single Particle Analysis (SPA) has progressed to the point where structures can be determined routinely to better than 2Å on a 300 kV microscope. (jeolusa.com)
lt;p>MicroED can be applied on every new electron microscope in the JEOL TEM line-up. (jeolusa.com)

Determining the Nanoscale Chemistry and Behavior of Interfaces and Phases in Al-Si(-Cu-Mg) Nanoparticles Using In-Situ TEM', (invited paper) in 14th European Microscopy Congress - Vol. 2, Aachen, Germany, p. 633 (2008). (virginia.edu)

Microscopy and Microanalysis, Vol. 12, Issue. (cambridge.org)
Microscopy and Microanalysis 18 (2012), p.995. (emc-proceedings.com)

The new approach has the potential to replace the complicated combination of different characterization techniques such as diffraction in a synchrotron, optical spectroscopy and microscopy. (ipcms.fr)
Graphene, carbon nanotube and other soft-mater materials suffers irradiation damage caused by high energy electron beam during TEM characterization. (denssolutions.com)
Advances in electron microscopic characterization technology have greatly improved the ability to quantify real microstructures found in Nd-Fe-B magnets. (hindawi.com)

Here we demonstrate the ability of ultrafast transmission electron microscopy to simultaneously image both the spatial interference and the quantization of such confined plasmonic fields. (nature.com)

In addition to selected publications provided below, I have authored or co-authored the following books in these research areas: "Interfaces in Materials" (1997), "In-Situ Electron Microscopy" (2012), and "Transmission Electron Microscopy and Diffractometry of Materials" (4th edition 2013). (virginia.edu)
The nanostructures were grown in porous silicon substrates in situ within the TEM by the electron beam-induced deposition method. (springer.com)

X-ray crystallography (MX) and electron cryomicroscopy (cryoEM) are the dominant methods for determining the structures of biological macromolecules. (dectris.com)
Mathew Peet, Richard Henderson and Chris Russo from the Laboratory of Molecular Biology in Cambridge have shown that questions of energy are pertinent to radiation damage in cryoEM as well (Reference 2). (dectris.com)
A couple of papers published only a few months apart illuminate the virtues of unconventional energies for MX and cryoEM data collection. (dectris.com)

She obtained her Ingeneer degree (physics) and her PhD degree (design of a new energy filter for transmission electron microscopy, under the direction of Prof. B. Jouffrey) at the Ecole Centrale in Paris. (epfl.ch)
Transmission electron microscopy (TEM) is the only technique able to characterize the nature of buried interfaces in these engineered van der Waals crystals and hence to provide insights into their optical, electronic and mechanical properties. (mrs.org)
Intriguing phenomena arising at the atomic scale have been found in functional complex oxide materials in recent years due to significant progress in technical and methodological development in scanning transmission electron microscopy (STEM). (mrs.org)
The CCOR Cc/Cs-corrector for transmission electron microscopy (TEM) was developed within the TEAM project to enable a resolution of only 0.5 Angström (0.05 nm) in TEM. (ceos-gmbh.de)
Here atom probe tomography, transmission electron microscopy and electron beam-induced current are used to clarify the dependence of Se content on the photoactive properties of CdTe x Se 1₋x alloy layers in bandgap-graded CdTe solar cells. (osti.gov)
When Gatan, a company specializing in transmission electron microscopy (TEM), and EDAX, a leader in analytical scanning electron microscopy techniques, including energy dispersive x-ray spectroscopy (EDS), wavelength dispersive spectroscopy (WDS), and electron backscatter diffraction (EBSD) decided to merge, it created a unique and exciting environment. (edaxblog.com)

Conventional and high angular resolution electron backscatter diffraction (EBSD) analysis were then used to explore morphology, deformation fields, and orientation relationships between the zirconium matrix and hydrides. (imperial.ac.uk)

By mapping the near-field interaction with ultrashort electron pulses in space and time, we trace the lifetime of the the microresonator following a femtosecond excitation and observe the spectral response of the cavity. (nature.com)
Measured temporal and energy resolution at different bias settings for intense electron pulses. (ipcms.fr)
A temporal resolution of approximately 1 ps can be achieved with weak electron pulses. (ipcms.fr)
Our experiments are accomplished by spatiotemporally overlapping electron and light pulses on a single nanowire suspended on a graphene film. (nature.com)
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. (lookformedical.com)

Collect 4D STEM data of the highest possible quality with our precise and reliable electron-counting detectors. (dectris.com)
The form of energy-filtered characteristic loss STEM lattice images is discussed, and the effects of partial localization on these images described. (elsevierpure.com)
Annular dark field STEM images of graphene ribbon arrays sculpted in a reproducible way by using a script-controlled electron beam at elevated temperature. (denssolutions.com)
Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy. (neurotree.org)

This is the only fully integrated hybrid-pixel electron detector with Gatan Microscopy Suite® (GMS) software for advanced electron diffraction studies. (dectris.com)
Energy-filtered electron diffraction studies were done in a Phillips CM-200 TEM at 200 kV using a Gatan imaging filter. (springer.com)

The potential benefits of using higher X-ray energies for macromolecular crystallography. (dectris.com)

Here a focussed electron probe is scanned across the sample and at each position of the scanning beam the corresponding diffraction pattern is recorded. (emc-proceedings.com)
The development of electron and scanning probe microscopies in the second half of the twentieth century has produced spectacular images of the internal structure and composition of matter with nanometer, molecular, and atomic resolution. (springeropen.com)

The interpretation of microdiffraction patterns from crystals formed with a coherent electron probe which is "smaller" than the crystal unit cell is discussed, with particular reference to the problem of extracting atomic number information. (elsevierpure.com)
Here, we reveal a temperature-dependent self-repair mechanism that allows near-damage-free atomic-scale sculpting of graphene using a focused electron beam. (denssolutions.com)
Nowadays, the new nanoanalytical electron microscopic techniques with atomic resolution allow the creation of precise microstructural models suitable for the numerical micromagnetic calculation of the demagnetization curve including the coercive field value. (hindawi.com)
Understanding the protective ability of the native oxide on an Fe-13 at% Cr alloy at the atomic scale: A combined atom probe and electron microscopy study. (mpie.de)
More recently he has invented and developed a number of iterative computational approaches for solving the phase problem in the context of short-wavelength (atomic scale) microscopy. (royalsociety.org)
The ultimate goal for local imaging and spectroscopy techniques is to measure and correlate structure-property relationships with functionality - by evaluating chemical, electronic, optical, and phonon properties of individual atomic and nanometer-sized structural elements [ 1 ]. (springeropen.com)

The definition refers to the coupling between collective oscillations of electrons in the metal, that is, surface plasmons, and the resulting radiated electromagnetic field, the polariton, which is evanescently confined in the direction perpendicular to the interface. (nature.com)

However, it differs in a fundamental way in that electrons are used, which, owing to the substantially larger scattering cross-section of electrons with biological matter, means much smaller crystals can be used. (jeolusa.com)

The fields currently covered are: - Computational Electron Microscopy with the JEMS programm (P. Stadelmann) - Angular resolved Electron Energy Loss Spectrometry (C. Hébert) - Three dimensional imaging and Chemical Analysis in a FIB. (epfl.ch)
The residual chromatic aberrations are so small that a large energy window of about 1 keV can be imaged with hardly any defocus variations (achromatic imaging). (ceos-gmbh.de)
He was the first to demonstrate the method of ptychography at visible-light, X-ray and electron wavelengths: an imaging technique which is now being widely adopted. (royalsociety.org)

L Jin, J. Bartel, C Jia and K.W. Urban Ultramicroscopy 176 (2017) 99-104). (ceos-gmbh.de)

Traueranzeige Elmar Zeitler, Der Tagesspiegel 27 December 2020, retrieved 27 December 2020 Experimental Cell Research Vol. 12 (1967) Symposium Washington D.C.: Quantitative Electron Microscopy "Utenlandske medlemmer" (in Norwegian). (wikipedia.org)

The enhanced interaction with the optical whispering-gallery modes of dielectric microresonators induces a strong phase modulation on co-propagating electrons, which leads to a spectral broadening of 700 electronvolts, corresponding to the absorption and emission of hundreds of photons. (nature.com)
Kfir, O. Entanglements of electrons and cavity photons in the strong-coupling regime. (nature.com)
The radiation that produces the data (X-ray photons and electrons, respectively) damages biological material. (dectris.com)
Experimenters can choose an energy just below the absorption edge of cadmium (26.7 keV) to take advantage of the detector's near-perfect quantum efficiency and the high-energy photons' low relative damage. (dectris.com)
The number of elastically scattered photons increases faster than the observed damage with the photon energy increasing to around 30 keV. (dectris.com)

In a pump-probe approach, chemical reactions are induced thermally by an intense laser pulse and studied after an adjustable delay with a nanosecond electron pulse in the TEM. (ipcms.fr)

DECTRIS ELA® electron-counting detector offers best-in-class performance in terms of detector noise, frame rate, and dynamic range. (dectris.com)
Discover DECTRIS ELA® detector that is fully integrated into electron microscopy instruments. (dectris.com)
In a joint publication in Ultramicroscopy, Nion and DECTRIS tested and characterized DECTRIS ELA® hybrid-pixel electron detector and its application potential. (dectris.com)
If you are interested in trying out a DECTRIS ELA® hybrid-pixel electron detector in your experimental setup, contact us. (dectris.com)
At DECTRIS, we offer you the right detector for the right energy. (dectris.com)

Compared to the use of a monochromator for resolution improvment Cc correction offers a much more intense electron beam at the same or better image resolution and therefore allows much shorter exposure times hence higher throughput. (ceos-gmbh.de)

SerialEM was first introduced on a JEOL JEM-2200FS in 2006 and is now fully compatible with all of JEOL's electron microscopes. (jeolusa.com)

Electron energy loss spectroscopy allows one to look at chemical binding states of 100-nm thin section specimens, with about 0.5-eV energy resolution in most instruments and a spatial resolution of 5 nm or better. (nationalacademies.org)

We demonstrate that by sculpting at temperatures above 600 C, an intrinsic self-repair mechanism keeps the graphene in a single-crystalline state during cutting, even though the electron beam induces considerable damage. (denssolutions.com)
For graphene it was observed in SALVE I-II that the upper limit of available scattering angles in momentum-resolved energy-loss spectra can be considerably extended at 40 kV without damaging the sample [ 14 ]. (salve-project.de)

After working in chemical industry (Bayer Leverkusen) 1954-58, he started to work on the quantitative aspects of electron microscopy during a stay at the Department for Cell Research and Genetics at the Karolinska Institutet in Stockholm under the direction of Torbjörn Caspersson in 1958. (wikipedia.org)
The quantitative electron microscopy remained the main topic of his research, which he continued at the Biophysical Department of the Walter Reed Army Medical Center in Washington, DC. (wikipedia.org)
In 1964, he organized a symposium about "Quantitative Electron Microscopy" together with G. Bahr. (wikipedia.org)

Simultaneously record the Zero-Loss Peak (ZLP) and the core-loss features that are present in the spectrum with our radiation-hard, high-dynamic-range electron detectors. (dectris.com)
The energy selecting window used to filter the electron diffraction pattern was 10 eV and was centered at the zero loss peak of the electron energy loss spectrum. (springer.com)

Demonstration of electron acceleration in a laser-driven dielectric microstructure. (nature.com)
Breuer, J. & Hommelhoff, P. Laser-based acceleration of nonrelativistic electrons at a dielectric structure. (nature.com)

We investigated and will investigate low-dimensional and bulk electron-beam sensitive materials such as carbon nanomaterials, thin polymers and single molecules, but also oxides and/or doped semiconductors. (salve-project.de)

Leading the Center for Electron Microscopy, I see my task as beeing threefold: -- guarantee a high level Electron Microscopy at EPFL by providing research in new techniques of Electron Microscopy. (epfl.ch)
An initial increase in ductility was observed when increasing the temperature from 100 °C to 570 °C, followed by a significant loss in ductility when samples were produced at 770 °C. A suite of multi-scale characterisation techniques revealed that the as-printed microstructure was drastically different across the range of temperatures. (imperial.ac.uk)

His research makes extensive use of synchrotron radiation facilities and Free-Electron Lasers with a big activity at the Diamond Light Source. (royalsociety.org)

The correction of the chromatic aberration Cc does not only considerably improve the TEM's information limit (resolving power), but also enables a much higher image contrast due to the additional contrast contribution of inelastically scattered electrons which otherwise only form a blurred image background in Cc-uncorrected images. (ceos-gmbh.de)
The CCOR manages that those electrons still largely contribute to the image contrast. (ceos-gmbh.de)
Higher image contrast due to additional high-resolution contrast contribution from inelastically scattered electrons by Cc correction. (ceos-gmbh.de)
The energy dependence of contrast and damage in electron cryomicroscopy of biological molecules. (dectris.com)

Creating, manipulating, and detecting coherent electrons is at the heart of future quantum microscopy and spectroscopy technologies. (bvsalud.org)

Here, we describe electron field emission from a monocrystalline, superconducting niobium nanotip at a temperature of 5.9 K. The emitted electron energy spectrum reveals an ultranarrow distribution down to 16 meV due to tunable resonant tunneling field emission via localized band states at a nanoprotrusion's apex and a cutoff at the sharp low-temperature Fermi edge. (bvsalud.org)

Micro electron diffraction, or microED, is a technique aimed at solving structures of biological macromolecules by electron diffraction. (jeolusa.com)

Joshua Dickerson and Elspeth Garman from the University of Oxford have run simulations to show that the diffraction power of a crystal grows faster than the absorbed dose as the photon energy increases to about 30 keV (Reference 1). (dectris.com)

At synchrotron beamlines where such high-energy radiation is available, these experiments are currently being performed. (dectris.com)
Experiments within our SALVE I-III project comprises the practical application of low-voltage microscopy for materials science problems. (salve-project.de)
Experiments in Work Package (B): Spectroscopy have been conducted during SALVE I-II. (salve-project.de)

Carbone, F., Kwon, O.-H. & Zewail, A. H. Dynamics of chemical bonding mapped by energy-resolved 4D electron microscopy. (nature.com)

We demonstrate this by producing electron vortex beams. (bvsalud.org)

This is an order of magnitude lower than for conventional field emission electron sources. (bvsalud.org)

Together with Günter Bahr, he was the first to publish about the determination of molecular weight by using electron microscopy. (wikipedia.org)

The natural matching of free electrons to these quintessential optical modes could enable the application of integrated photonics technology in electron microscopy, with broad implications for attosecond structuring, probing quantum emitters and possible electron-light entanglement. (nature.com)
Leveraging and specifically altering the quantum features of an electron beam source at low temperatures can enhance its emission properties. (bvsalud.org)
Data acquisition at low dose and high frame rates (up to 9 kHz) allowed them to count individual electrons and get a high quantum efficiency. (dectris.com)

This source will decrease the impact of lens aberration and enable new modes in low-energy electron microscopy, electron energy loss spectroscopy, and high-resolution vibrational spectroscopy. (bvsalud.org)
The increasing demand of high-performance rare earth permanent magnets with a high coercive field and an energy density product value suitable for large scale applications in wind turbines and electrically powered automotive devices led to the development of heavy rare earth lean/rare earth-free Nd-Fe-B based magnets and to the optimization of the complex multiphase microstructure of the magnets [ 1 ]. (hindawi.com)
Ab initio vacancy formation energies and kinetics at metal surfaces under high electric field. (mpie.de)

The e-beam damage limits the observation time or observation electron beam condition, thus requiring a way to prevent. (denssolutions.com)

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes1

Cryo-electron m2

EELS10

Valence electron energy-loss1

Microscope10

European Microscopy Congress1

Microanalysis2

Characterization3

Ultrafast1

Situ2

CryoEM3

Transmission6

Backscatter diffraction1

Pulses5

STEM4

Diffraction studies2

Crystallography1

Scanning2

Atomic6

Plasmons1

Crystals1

Imaging3

20171

20201

Photons5

Probe1

Detector5

Intense electron1

Microscopes1

Specimens1

Graphene2

Quantitative3

Zero-Loss Peak2

Acceleration2

Polymers1

Techniques2

Synchrotron Radiation1

Contrast4

Coherent1

Spectrum1

Biological1

Photon1

Experiments3

Dynamics1

Demonstrate1

Conventional1

Molecular1

Quantum3

High3

Observation1