• Male C57BL/6 mice were injected with a murine model of human papillomavirus (HPV+)-induced oropharyngeal squamous cell carcinoma in their right hindlimb to induce tumor growth. (nih.gov)
  • Oropharyngeal squamous cell carcinoma (OPSCC), largely fueled by the human papillomavirus (HPV), has a complex biological and immunologic phenotype. (wustl.edu)
  • Zhang Y, Sturgis EM , Dahlstrom KR , Wen J, Liu H, Wei Q, Li G , Liu Z. Telomere length in peripheral blood lymphocytes contributes to the development of HPV-associated oropharyngeal carcinoma. (viictr.org)
  • Jin L, Sturgis EM , Zhang Y, Huang Z, Song X, Li C, Wei Q, Li G . Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma. (viictr.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • Oral squamous cell carcinoma (OSCC) includes malignant neoplasms of the lip, oral cavity and oropharynx. (biomedcentral.com)
  • Carcinoma of the tongue is one of the most commonly occurring neoplasms among all oral tumors i.e. (heraldopenaccess.us)
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • Established viral infections postulated to play a role in carcinogenesis are Epstein Barr Virus (EBV) in NPC, and increasingly evident is the association between Human Papilloma Virus (HPV) and oropharyngeal carcinoma (which is linked to sexual practices). (healthxchange.sg)
  • A growing body of research shows that human papillomavirus (HPV) is a common and increasing cause of oropharyngeal squamous cell carcinoma (OSCC). (cdc.gov)
  • Transoral robotic surgery for oropharyngeal squamous cell carcinoma: a prospective study of feasibility and functional outcomes. (jamanetwork.com)
  • Carcinoma of the tongue base treated by transoral laser microsurgery, part one: untreated tumors, a prospective analysis of oncologic and functional outcomes. (jamanetwork.com)
  • The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. (uchicago.edu)
  • Oral cavity and oropharyngeal squamous cell carcinoma genomics. (uchicago.edu)
  • Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma. (uchicago.edu)
  • The Impact of Tonsillectomy upon the Risk of Oropharyngeal Carcinoma Diagnosis and Prognosis in the Danish Cancer Registry. (uchicago.edu)
  • Disease-free survival after salvage therapy for recurrent oropharyngeal squamous cell carcinoma. (uchicago.edu)
  • In oral squamous cell carcinoma (OSCC), modern DNA technology, especially allelic imbalance (loss of heterozygosity) studies, have identified chromosomal changes suggestive of the involvement of tumor suppressor genes (TSGs), particularly in chromosomes 3, 9, 11, and 17. (medscape.com)
  • Second primary tumors (SPTs) have a significantly worse prognosis on patients with head and neck squamous cell carcinoma (HNSCC) (1). (bvsalud.org)
  • A Pancoast tumor is a rare form of lung cancer that occurs mainly in the apex of the lung as the main symptom of upper extremity pain. (jkds.org)
  • If oropharyngeal dysphagia is suspected, VFSS should be performed to prevent complications leading to mortality from lung cancer. (jkds.org)
  • This study estimated the relative frequencies of oral and pharyngeal cancers among Yemeni cancer patients registered in 2007 and 2008 and determined patients' demographic and tumour characteristics. (who.int)
  • RÉSUMÉ Des études en milieu hospitalier ont révélé des fréquences relatives très élevées du cancer oropharyngé au Yémen. (who.int)
  • La présente étude a estimé les fréquences relatives du cancer de la cavité buccale et du pharynx chez des patients yéménites atteints de cancers enregistrés en 2007 et 2008. (who.int)
  • For the included cases, Of the 541 cases of oropharyngeal are believed to reflect different preva- tumour staging was reclassified and cancer 19.2%, 11.8%, 8.7% and 7.8% lences and patterns of risk habits such coded according to the SEER summary were referred from Al-Hodeida, Taiz, as khat chewing and waterpipe smoking staging manual 2000 [16]. (who.int)
  • To describe the epidemiological profile of patients with oral and oropharyngeal cancer treated at a referral hospital in Salvador, Brazil. (bvsalud.org)
  • Patients with oral and oropharyngeal cancer are mostly male, older than 60 years, with low educational level, and working as farmers. (bvsalud.org)
  • The high prevalence as well as the high mortality rate of oral and oropharyngeal cancer in the Brazilian population need to be investigated through epidemiological studies, not only for monitoring this disease, but also in order to characterize at-risk populations and optimize the public health policies aimed at prevention, protection and health care [1,3]. (bvsalud.org)
  • In this sense, the purpose of this study was to analyze the epidemiological profile of the individuals with oral and oropharyngeal cancer treated at HAM in the period of 2008 to 2015, taking into account sociodemographic and disease-related aspects. (bvsalud.org)
  • Introduction: Overexpression of p16 (p16+) is a surrogate marker of human-papillomavirus infection and prognosis in oropharyngeal cancer, and its role in head and neck squamous cell cancer (HNSCC) is under study. (edu.pe)
  • Zhang F, Sturgis EM , Sun Y, Zhang Y, Wei Q, Zhang C, Zheng H, Li G . Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy. (viictr.org)
  • Zhang Y, Sturgis EM , Sun Y, Sun C, Wei Q, Huang Z, Li G . A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk and HPV-positive tumours of oropharyngeal cancer. (viictr.org)
  • Influence of smoking history on imaging characteristics among patients with human papillomavirus-positive oropharyngeal cancer: a blinded matched-pair analysis. (viictr.org)
  • Song X, Sturgis EM , Huang Z, Li X, Li C, Wei Q, Li G . Potentially functional variants of p14ARF are associated with HPV-positive oropharyngeal cancer patients and survival after definitive chemoradiotherapy. (viictr.org)
  • The prevalence of oral cavity and oropharyngeal cancer has geographic variations, with the highest rate reported in India, accounting for 50% of all cancer cases in that country. (medscape.com)
  • Perform staging of the tumor according to the American Joint Committee on Cancer staging protocol because this is of critical importance to the patient's prognosis. (medscape.com)
  • Specific treatment of palate cancer depends on the location of the tumor (hard vs soft palate), stage of the tumor, and pathologic type of the cancer. (medscape.com)
  • It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer. (lookformedical.com)
  • Tumors or cancer of the MOUTH. (lookformedical.com)
  • Tumors or cancer of the SKIN . (lookformedical.com)
  • Tumors or cancer of the LUNG. (lookformedical.com)
  • Tumors or cancer of the LIVER. (lookformedical.com)
  • Tumors or cancer of the UTERINE CERVIX. (lookformedical.com)
  • Condyloma acuminata endometrial cancer lining thickness long does it last que es cancer papiloma humano, cancer de prostata juvenil kurkuma en human papillomavirus. (info-tecuci.ro)
  • Schutz vor Viren: HPV-Impfung für Jungen - BR24 ghimbir flatulenta Cancer la plamani in stadiul 4 papillary urothelial neoplasm of low malignant potential treatment, cancerul de piele este periculos cancer intestinal bacteria. (info-tecuci.ro)
  • Prevention of papillomavirus cancer cerebral agresiv, intraductal papilloma breast pathology outlines tumor ductal papilloma. (info-tecuci.ro)
  • Virus del papiloma humano cancer de cuello uterino plantar hpv impfung jungen kkh on foot keeps coming back, papiloma humano en mujeres tipo 16 cancer hpv impfung jungen kkh celulas claras sobrevida. (info-tecuci.ro)
  • ABSTRACT A retrospective cohort study was conducted to determine the 5-year survival and prog- nostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996-2000. (who.int)
  • A search constitutes 0.6%-5% of all human malig- was made for cases of oropharyngeal cancer nant tumours [ 5 ]. (who.int)
  • The registers of oropharangeal cancer cases the area in the world with the highest inci- were reviewed to collect personal and clini- dence of oral cancer was Melanesia (31.5 cal data about the site, size, histopathologi- per 100 000 in men and 20.5 per 100 000 cal type, grading and staging of the tumour. (who.int)
  • Tumors or cancer of the PHARYNX. (ouhsc.edu)
  • Throat cancer treatment includes pharmacotherapy, radiotherapy, chemotherapy, and surgical procedures that involve removing a part or even the entire throat together with the neoplastic tumor. (health-alphabet.com)
  • Patients with oropharyngeal cancer have the best prognosis then. (health-alphabet.com)
  • However, one of the worst-prognostic neoplasms not only of the throat, but also of the head and neck, is laryngeal cancer. (health-alphabet.com)
  • Ramqvist T, Dalianis T. Oropharyngeal Cancer Epidemic and Human Papillomavirus. (cdc.gov)
  • Soft palate carcinomas are staged as oropharyngeal cancers according to the American Joint Committee on Cancer (see Staging). (medscape.com)
  • The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature. (jamanetwork.com)
  • Prevalence and predictive role of p16 and epidermal growth factor receptor in surgically treated oropharyngeal and oral cavity cancer. (jamanetwork.com)
  • Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer. (uchicago.edu)
  • Serum Antibodies to HPV16 Early Proteins Warrant Investigation as Potential Biomarkers for Risk Stratification and Recurrence of HPV-Associated Oropharyngeal Cancer. (uchicago.edu)
  • Mouth (oral) cancer is a major neoplasm worldwide and accounts for most head and neck cancers. (medscape.com)
  • The etiology of SCC appears to be multifactorial and strongly related to lifestyle, mostly habits and diet (particularly tobacco alone or in betel, and alcohol use).Other factors such as infective agents may also be implicated, particularly in oropharyngeal cancer. (medscape.com)
  • 6) described features of what they called "field cancerization" suggesting that oral and oropharyngeal cancer can develop precancerous changes in multifocal areas, presenting abnormal tissue surrounding the lesion. (bvsalud.org)
  • Persistent infection with oncogenic HPV types can cause cervical cancer in women as well as other anogenital and oropharyngeal cancers in women and men. (cdc.gov)
  • Although most infections cause no symptoms and are self-limited, persistent HPV infection can cause cervical cancer in women as well as other anogenital cancers, oropharyngeal cancer, and genital warts in men and women. (cdc.gov)
  • oral and oropharyngeal cancers, whereas the majority of not-related to viral infection tumors constitute lip and thyroid cancers. (healthanddietblog.info)
  • Nonsquamous cell cancers, including minor salivary gland cancers, sarcomas, and melanomas, account for the other half (see the histologic distribution of hard palate malignant neoplasms and the histologic types and frequencies of minor salivary gland neoplasms of the palate, below). (medscape.com)
  • Chapter 32 Gastrointestinal Cancers DIAGNOSIS TREATMENT DIAGNOSITC IMAGING MEDICATIONS CT scan, MRI, labeled somatostatin receptor-based diagnostic imaging ▪ Localization, TNM staging ▪ Presence of hepatic lesions SURGERY Endoscopy with biopsy ▪ Tumor visualization ▪ Histopathological analysis, grading ▪ Somatostatin analogues suppress tumor proliferation, decrease symptoms ▪ Surgical removal of tumor LAB RESULTS ▪ 5-hydroxyindoleacetic acid, chromogranin Figure 32.2 Gross pathology of carcinoid tumor of the terminal ileum. (osmosis.org)
  • High-risk HPV is implicated in causation of various other cancers such as anal cancers, oropharyngeal cancers, vulval cancers, vaginal cancers, and penile cancers. (cytojournal.com)
  • Gillison ML. Current topics in the epidemiology of oral cavity and oropharyngeal cancers. (jamanetwork.com)
  • We analyzed OPSCC patients treated between 2000 and 2016 and correlated locoregional control (LRC), disease-free survival (DFS) and overall survival (OS) with conventional clinical parameters, risk parameters generated using deep-learning algorithms trained to quantify tumor-infiltrating lymphocytes (TILs) (OP-TIL) and multinucleated tumor cells (MuNI) and targeted transcriptomics. (wustl.edu)
  • [ 17 ] However, at the tumor margins, the epithelial fronds tend to penetrate deep into the brain tissue. (medscape.com)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • A malignant epithelial tumor with a glandular organization. (lookformedical.com)
  • Mixed mesenchymal and epithelial tumors are of Mullerian origin. (cytojournal.com)
  • Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
  • We plan to compare ultrasound evaluation of tumor staging, tumor volume, and tumor recurrence in patients with tumors of the larynx, oral cavity and hypopharynx. (knowcancer.com)
  • In the case of smaller tumors located in the lower pharynx, the doctor may use laryngectomy - a procedure involving partial or total removal of the larynx. (health-alphabet.com)
  • It can hpv cause benign tumors been demonstrated that the human papil-loma-virus HPV type 16, a subtype of the human pa-pil-loma-virus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive. (info-tecuci.ro)
  • Comparison of 2 line blot assays for defining HPV genotypes in oral and oropharyngeal squamous cell carcinomas. (ouhsc.edu)
  • BACKGROUND AND PURPOSE: Patients with human papillomavirus-positive oropharyngeal squamous cell carcinomas have a better survival rate than those with human papillomavirus-negative oropharyngeal squamous cell carcinomas. (vu.nl)
  • MATERIALS AND METHODS: Forty-four patients with oropharyngeal squamous cell carcinomas underwent pretreatment DWI. (vu.nl)
  • CONCLUSIONS: No significant association between ADC and human papillomavirus status was found in oropharyngeal squamous cell carcinomas. (vu.nl)
  • In our study population, differences in genetic and histologic features between human papillomavirus-positive and human papillomavirus-negative oropharyngeal squamous cell carcinomas did not translate into different ADC values. (vu.nl)
  • We explored whether human papillomavirus status and ADC values are independent tumor characteristics.MATERIALS AND METHODS: Forty-four patients with oropharyngeal squamous cell carcinomas underwent pretreatment DWI. (vu.nl)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • Congruently, primary tumor volume has proven to be an important parameter. (lu.se)
  • The current study aims to investigate the role of primary tumor volume, OTT and estimate α/β-ratio for p16-positive OPSCC, and to quantify the differences in radiosensitivity depending on p16-status. (lu.se)
  • METHODS: A cohort of 523 patients treated with RT was studied using a tumor control probability (TCP)-model that incorporates primary tumor volume (V) raised to an exponent c, OTT and α/β-estimation. (lu.se)
  • CONCLUSION: Primary tumor volume plays a crucial role in predicting local tumor response, particularly in p16-positive OPSCC. (lu.se)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • ADC values for the primary tumors were determined by using 3 b-values in an ROI containing the largest area of solid tumor on a single section of an axial DWI image. (vu.nl)
  • Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. (uchicago.edu)
  • Hemangiosarcomas are locally invasive and multicentric ( having two or more primary tumors ). (ivis.org)
  • Another threatening element to the patients' survival chances and quality of life is the high risk of developing a second primary tumor (SPT). (bvsalud.org)
  • They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. (lookformedical.com)
  • The aim of the study was to compare the dynamics of oral and oropharyngeal muscles contraction during swallowing in normal individuals and in patients with malignant tumors depending on the clinical disease using ultrasound. (edu.ua)
  • The study included 29 patients aged 38-55 years (men), normtrophic, who were treated in the Department of Head and Neck Tumors of Podolsk Regional Oncology Center for malignant tumors of the tongue, floor of the mouth and oropharynx. (edu.ua)
  • In patients with malignant tumors of the lateral tongue surface, the longitudinal examination of the sublingual muscle group in B-mode ultrasound showed decreased indicators by 7 % and in the lateral projection of the anterior belly of the digastric muscle in M-mode - by 3.5 times. (edu.ua)
  • Patients will be seen who are enrolled in NCI and NIDCD protocols for head and neck tumors. (knowcancer.com)
  • A few letters were received from rates for malignant neoplasm of the lip, oral the relatives of patients reporting their death cavity and pharynx were 0.3 per 100 000 and date of death. (who.int)
  • Almost half of patients present with extension of the tumor beyond the soft palate. (medscape.com)
  • Frequently, patients who develop SPTs are relatively young, presented a first tumor diagnosed in early stages at sites favourable to treatment, factors which, at the same time, increase the chance both of survival and SPT development (2). (bvsalud.org)
  • While ultrasound technology has been used extensively in Europe to evaluate tumors of the head and neck, its use in this country has been marginal. (knowcancer.com)
  • Jäckel MC, Martin A, Steiner W. Twenty-five years experience with laser surgery for head and neck tumors: report of an international symposium, Göttingen, Germany, 2005. (jamanetwork.com)
  • Figure 32.1 Histological appearance of a carcinoid tumor of the lung. (osmosis.org)
  • Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. (uchicago.edu)
  • These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)
  • We plan to compare CT/MRI results with ultrasound to determine if this non-invasive technique can be utilized reliably for diagnosis and tracking of oropharyngeal tumors. (knowcancer.com)
  • Provides a tumor tissue sample obtained at the time of or after the initial diagnosis of R/M HNSCC. (who.int)
  • El estado p16+ se asoció con TILalto en orofaringe (p=0.02) pero no en cavidad-oral (p=0.43). (edu.pe)
  • 1.41-11.72), tumour site and patient's age. (who.int)
  • Squamous papillary tumors (seen predominantly in adults) generally involve only a solid component, which is typically seen without calcifications. (medscape.com)
  • Mixed tumors are a combination of the adamantinomatous and papillary forms. (medscape.com)
  • In addition, tumor models were characterized in vivo in C57Bl/6NCrl mice in terms of their histological properties, tumor growth kinetics, and radiosensitivity. (biomedcentral.com)
  • However, most findings come from an era when p16-negative HNSCC was the dominant tumor type. (lu.se)
  • The estimated α/β-ratio for p16-positive oropharyngeal tumors aligns with previous HNSCC studies, whereas the impact of prolonged OTT was slightly less than previously reported. (lu.se)
  • Differential gene expression (DEG) analysis demonstrated overlap between MuNI and OP-TIL and identified genes involved in DNA repair, oxidative stress response and tumor immunity as the most prominent correlates with survival. (wustl.edu)
  • Specifically the research showed that the most significantly deregulated genes in the HPV-positive tumors are cell cycle regulators. (moffitt.org)
  • [ 1 ] ETP-ALL frequently has mutations in RUNX1 and/or ETV6 in addition to genes that are more commonly associated with myeloid neoplasms and are otherwise rare in T-cell lymphoblastic leukemia/lymphoma (such as FLT3 , IDH1/2 , TET2 , and DNMT3A mutations). (medscape.com)
  • Etiologies for the development of tumors include long-term exposure to ultraviolet ( UV ) light and a genetic predisposition. (ivis.org)
  • Determinants of paclitaxel penetration and accumulation in human solid tumor. (ouhsc.edu)
  • For ulcerative lesions, obtaining a biopsy specimen from closer to the edge of the tumor is important to avoid the necrotic central component. (medscape.com)
  • Characterization of the resulting MOC1-HPV cell lines and tumor models confirmed stable expression of HPV-16 oncogenes and differences in cell morphology, in vitro migration capacity, and tumor microenvironment characteristics. (biomedcentral.com)
  • Characteristics of the newly developed HPV-positive OSCC tumor models correlate with the transcriptomic profile of MOC1-HPV cell lines. (biomedcentral.com)
  • We explored whether human papillomavirus status and ADC values are independent tumor characteristics. (vu.nl)
  • The concept does not refer to neoplasms located in tissue composed of squamous elements. (lookformedical.com)
  • Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)
  • Although a fresh tumor tissue sample obtained within 90 days of screening is highly preferred, an archival tumor specimen (=2 years old) is acceptable. (who.int)
  • Ellies M, Steiner W. Peri- and postoperative complications after laser surgery of tumors of the upper aerodigestive tract. (jamanetwork.com)
  • The strong relationship between tumor immunity and oncologic outcomes in OPSCC regardless of HPV status may provide opportunities for further biomarker development and precision oncology approaches incorporating immune checkpoint inhibitors for maximal anti-tumor efficacy. (wustl.edu)
  • Oropharyngeal dysphagia is not a common symptom. (jkds.org)
  • This case report describes a 57-year-old male patient with a Pancoast tumor who presented with oropharyngeal dysphagia. (jkds.org)
  • A video fluoroscopic swallow study confirmed the presence of oropharyngeal dysphagia, which was attributed to left glossopharyngeal and vagus nerve damage associated with the Pancoast tumor. (jkds.org)
  • This case highlights the need to be aware that a Pancoast tumor can cause oropharyngeal dysphagia. (jkds.org)