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Drug Metabolism and Personalized Therapy ( DMPT ) is the official journal of the European Society of Pharmacogenomics and Personalised Therapy (ESPT). (degruyter.com)
Specifically, it covers the following fields: pharmacogenetics, pharmacogenomics and drug metabolism research, dealing with established, new and potential drugs, herbal medicinal products, environmentally toxic chemicals, the mechanisms by which drugs and herbs can interact with each other and with biological systems, and the pharmacological and toxicological consequences of these interactions, as well as drug metabolism and excretion. (degruyter.com)

Research into endocrinology and metabolism touches upon many of the most important health problems of our time, including diabetes, obesity, hypertension, osteoporosis and hormonal disturbances. (ki.se)
At the same time, Karolinska Institutet is home to dynamic clinical research in endocrinology and metabolism. (ki.se)
The Department of Diabetes, Endocrinology & Metabolism offers a unique diabetes and endocrinology program combining groundbreaking research, innovative treatments with comprehensive patient education to help people living with diabetes and other endocrine diseases get the medical care and information they need to achieve optimal quality of life. (cityofhope.org)

Birth defects like inborn errors of metabolism and blood disorders of prenatal origin appear in other chapters. (who.int)
many of the diseases that are screened for are inborn errors of metabolism in which the baby's body cannot properly break down certain substances in food which can build up to toxic amounts. (cdc.gov)

International Journal of Diabetes and Metabolism (2002) 10 (1): 33-50. (karger.com)
Ginsenosides extracted from ginseng, which is derived from the roots and rhizomes of Panax ginseng C. A. Meyer, have been used in China as an adjuvant in the treatment of diabetes mellitus. (frontiersin.org)
Rg1, Rg3, Rb1, and compound K demonstrated the most promising therapeutic prospects as potential adjuvant medicines for the treatment of diabetes. (frontiersin.org)
A slow metabolism can be attributed to several factors: diabetes, unproportional fat to muscle ratio, lifestyle factors, conditions such as hypothyroidism and genetics. (earthclinic.com)
Several comorbid conditions increase the risk of vertigo, including diabetes and abnormal glucose metabolism, osteoporosis, high cholesterol, and depression and anxiety. (lifeextension.com)
Some conditions, like an underactive or overactive thyroid and diabetes, are hormonal diseases that affect your metabolism. (webmd.com)
Diabetes is a chronic disease characterized by chronic hyperglycaemia which requires lifelong treatment. (who.int)

Rifaximin treatment of SIBO patients ameliorated their mood disorders and gastrointestinal aliments underlined by changes in tryptophan metabolism. (biomedcentral.com)
Carbohydrate metabolism disorders are a group of metabolic disorders. (medlineplus.gov)
For some disorders, there is no cure, but treatments may help with symptoms. (medlineplus.gov)
Hereditary galactosemia is among the most common carbohydrate metabolism disorders and can be a life-threatening illness during the newborn period. (medscape.com)

The goal of the UCLA Interdisciplinary Training Program in Metabolism (ITPM) is to train the next generation of investigators who will advance prevention, treatment, and clinical care for metabolism-related diseases. (uclahealth.org)
Organic acidurias (acidemias) - a group of inherent diseases, which is characterized by the disorder of intermediate metabolism with the accumulation of carboxyl acids. (clingenetic.com.ua)

This is a whole new area in research on exercise metabolism, and we seem to have found another mechanism by which exercise can have beneficial effects," says Laurie Goodyear, Ph.D., Head of Joslin's Section on Integrative Physiology and Metabolism and senior author on a report on the work published in Cell Metabolism . (sciencedaily.com)
A recent Cell Metabolism study explores the therapeutic potential of circadian-modulating interventions to treat Alzheimer's disease (AD). (news-medical.net)

5. Carlezon, W.A. Jr. & Wise, R.A. Rewarding actions drug to its receptor, but rather by the rats, treatments associated with aversive of phencyclidine and related drugs in nucleus ac- failure of an expected drug injection to states such as severe drug withdrawal cumbens shell and frontal cortex. (lu.se)
In vitro interactions between organophosporous pesticides and consequences of pre-treatment with nicotine and alcohol on in vitro pesticide metabolism in rats. (cdc.gov)

Refsum disease and the hepatic porphyrias are rare inherited neurodegenerative conditions with exacerbations and remissions due to abnormal metabolism of large tetrapyrrole molecules. (medscape.com)
Abnormal metabolism and the evasion of apoptosis are considered hallmarks of cancers. (hindawi.com)
Some types of vertigo and dizziness are associated with abnormal glucose metabolism, osteoporosis, sleep apnea, and menopause and hormone fluctuations. (lifeextension.com)

By performing (13)C6-glucose metabolic flux analysis, we show for the first time that the tumors undergo metabolic re-programming toward anaerobic metabolism, thereby uncoupling glycolysis from oxidative phosphorylation. (edu.au)
In contrast to normal cells, most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactate fermentation, even in the presence of oxygen, a less efficient metabolism compared to a low rate of glycolysis followed by mitochondrial oxidation of pyruvate [ 2 ]. (hindawi.com)

Refsum disease is classified into 2 subgroups, based on differences in enzymes affected, metabolites accumulated, genetics, clinical presentation, and treatment: classic/adult Refsum disease and infantile Refsum disease. (medscape.com)

The effect of different hypocaloric carbohydrate (CHO) intakes was evaluated in 8 groups of obese patients in order to assess the role of the CHO and the other dietary sources in modulating the peripheral thyroid hormone metabolism. (nih.gov)
From these results it appears that the CHO content of the diet is more important than non-CHO sources in modulating peripheral thyroid hormone metabolism and that the influence of total calories is perhaps as pronounced as that of CHO when a "permissive" amount of CHO is ingested. (nih.gov)
when your metabolism is controlled by your Thyroid, which is controlled by iodine, then the arrow thing is out the window. (earthclinic.com)
But it lacks iodine, which your thyroid needs to manage your metabolism. (webmd.com)

In addition to its role in glucose metabolism, this pathway also regulates the redirection of free amino acids to protein synthesis via the mTOR-signaling pathway. (hindawi.com)

Increasing knowledge of the interplay between polyamine metabolism and other cancer-driving pathways, including the PTEN-PI3K-mTOR complex 1 (mTORC1), WNT signalling and RAS pathways, suggests potential combination therapies that will have considerable clinical promise. (nih.gov)
Bedaquiline should be used with clinical expert consultation as part of combination therapy (minimum four-drug treatment regimen) and administered by direct observation to adults aged ≥18 years with a diagnosis of pulmonary MDR TB (Food and Drug Administration. (cdc.gov)
A clinical study to evaluate of the combination of AHCC plus PLD in the treatment of ovarian cancer is being pursued. (researchgate.net)
The goal of treatment is to maintain clinical euthyroidism, with the mother's FT4 level in the high-normal range. (medscape.com)

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. (genomeweb.com)

This article describes the pathophysiology of, and treatment strategy for, cerebral ischemia. (nih.gov)

Specifically, an increase in the activity of the serotonin pathway of TRP metabolism in the group SIBO-D was observed. (biomedcentral.com)

Let's get back to to the importance of iodine and your metabolism. (earthclinic.com)
The boxed warning also states that propylthiouracil should be reserved for use in those who cannot tolerate other treatments such as methimazole, radioactive iodine, or surgery. (medscape.com)

Heme is an iron-containing tetrapyrrole essential for diverse biological functions, including gas transport and sensing, oxidative metabolism, and xenobiotic detoxification. (medscape.com)
Moreover, bevacizumab led to a depletion in glutathione levels indicating that the treatment caused oxidative stress in the tumors. (edu.au)

This session explores the links between nutritional-metabolic parameters and cardiovascular pathology in dialysis patients, describing fundamental mechanisms and the implications for treatment. (asn-online.org)
We here describe how human GBM adapts to bevacizumab treatment at the metabolic level. (edu.au)
Confirming the metabolic flux results, immunohistochemical analysis showed an up-regulation of lactate dehydrogenase in the bevacizumab-treated tumor core as well as in single tumor cells infiltrating the brain, which may explain the increased invasion observed after bevacizumab treatment. (edu.au)
In vitro metabolism study of carbofuran and its metabolic interaction with testosterone. (cdc.gov)

3) Transgender adults planning to take oral or injectable estradiol treatment. (iths.org)
In 2017, the AASM released an updated guideline for the pharmacologic treatment of chronic insomnia in adults. (medscape.com)

Hormones have an important role in the body's metabolism, in salt and water balance, in the regulation of blood pressure and temperature, in the formation of bone, muscle, and blood, and in human reproduction. (ki.se)

However, simple lifestyle changes and the addition of several natural substances to a balanced diet is often enough to regulate the metabolism, increase energy and constitute weight loss. (earthclinic.com)

In vitro studies have shown that CYP3A4 and CYP2E1 enzymes are involved in the metabolism of eszopiclone. (healthyplace.com)

These findings open up new avenues of research into exploiting aberrant polyamine metabolism for anticancer therapy. (nih.gov)
The purpose of this study is to find out how estradiol therapy affects a single tracer dose of approved medicines in the blood (midazolam, digoxin, and acetaminophen) and to confirm estradiol treatment does not affect natural bacterial in the gut. (iths.org)
The AASM guideline recommends psychological and behavioral interventions (including, but not limited to, cognitive-behavioral therapy [CBT]) as effective in the treatment of chronic comorbid insomnia as well as primary insomnia. (medscape.com)
Through a repetitive development process, and patient support for treatment adherence ( 7 ), such we suggest essential patient- and treatment-related as patient-centered directly observed therapy (DOT), characteristics that should be collected by prospective also varies by program. (cdc.gov)
Treatment measures include pharmacologic, surgical, and physical therapy. (medscape.com)
The primary treatment for the most common type of vertigo, caused by debris in the inner ear, is repositioning therapy, which can relieve vertigo in a single session when performed by a trained clinician. (lifeextension.com)

Plasma cholesterol metabolism was investigated in normotriglyceridemic patients with end-stage renal disease treated by hemo- or continuous ambulatory peritoneal dialysis (CAPD), and compared with that in a control group with normal renal function. (jci.org)
Results from a study funded by Australian Rotary Health (ARH) was aimed to identify novel treatment strategies for prostate cancer patients, which remains a leading cause of death for men in Australia. (australianrotaryhealth.org.au)
Use of the drug also can be considered for individual patients in other categories (e.g., persons with extrapulmonary TB, children, pregnant women, or persons with HIV or other comorbid conditions) when treatment options are limited. (cdc.gov)
The aim of this study was to assess the mental state and gastrointestinal complaints of patients with small intestinal bacterial overgrowth (SIBO) in relation to tryptophan metabolism and rifaximin treatment. (biomedcentral.com)
Changes in TRP metabolism were also observed in these patients. (biomedcentral.com)
International policy for treatment of multidrug- and ri- fampin-resistant tuberculosis (MDR/RR TB) relies large- from none to monthly sputum smear microscopy ly on individual patient data (IPD) from observational and cultures with periodic drug-susceptibility testing studies of patients treated under routine conditions. (cdc.gov)
These observations were further validated in a panel of eight human GBM patients in which paired biopsy samples were obtained before and after bevacizumab treatment. (edu.au)
These finding are particularly beneficial in the treatment of recurrent cancer when maintaining a good quality of life during chemotherapy is a priority and allows patients to have a natural, nutritional approach to preventing and managing chemotherapy adverse effects. (researchgate.net)
With no treatment, over 60% of patients with the most common type of vertigo (caused by debris in the inner ear) recover within four weeks. (lifeextension.com)
PTU should not be used in pediatric patients unless the patient is allergic to or intolerant of methimazole, and no other treatment options are available. (medscape.com)

Treating the symptoms of a slow metabolism requires a balanced approach that incorporates lifestyle changes as well as natural supplements. (earthclinic.com)
Slow metabolism is generally characterized by several symptoms as well. (earthclinic.com)
As with any chronic disease, patient education is vital to familiarize the patient with the symptoms, course, and treatment of the disease. (medscape.com)
His/Her metabolism stand unhealthy diets worse, suffering more easily from more symptoms than a person with a healthy/treated sense of balance. (sense-of-balance-dysfunction.com)

Treatments may include special diets, supplements, and medicines. (medlineplus.gov)

Curcumin (Cur), a possible anti-obesity compound, and piperine (Pip), a plausible enhancer of Cur's bioavailability and efficacy, may be candidate agents for controlling body fat, metabolism and low grade inflammation. (springer.com)
Better understanding of signals to burn energy may eventually lead to treatments for obesity. (sciencedaily.com)

Understanding the underlying mechanisms of disease, at a molecular level, is an essential precondition for the development of new methods of diagnosis and treatment. (ki.se)

The inhibition of pulp browning by EBR treatment was possibly attributed to preserving the cell membrane integrity, reducing total phenolic content , and decreasing PAL, PPO, and POD activities. (bvsalud.org)

Abdulaziz en consultation de suivi durant la période janvier 1997-décembre 2001. (who.int)

The Centers for Disease Control and Prevention (CDC) uses ABV to determine different drinking levels and note gender differences in alcohol metabolism. (aspenridgerecoverycenters.com)
He is committed to continue exploring novel mechanisms of acquired epilepsy and new approaches for epilepsy treatment and prevention. (hopkinsmedicine.org)
TB360 trade name] is indicated in children weighing less than 25 kg, for the prevention and treatment of tuberculosis caused by the bacterium Mycobacterium tuberculosis . (who.int)
Countries are encouraged to create the conditions required for prevention, early detection diagnosis, treatment, guarantee of equitable access to care, and availability of drugs at health facilities. (who.int)

Advances in our understanding of the metabolism and molecular functions of polyamines and their alterations in cancer have led to resurgence in the interest of targeting polyamine metabolism as an anticancer strategy. (nih.gov)

Understanding human anatomy and how alcohol can impact chemicals in the brain is an important component in developing safe and proper treatments for alcohol use disorder (AUD). (aspenridgerecoverycenters.com)
When it is necessary to suspect metabolism disorder? (clingenetic.com.ua)

Tetrapyrrole molecules are large-ringed structures developed from 4 pyrrole groups and used in energy metabolism in both plants and animals. (medscape.com)
Metabolism - the chemical turnover of the body - encompasses the body's chemical reaction pathways that e.g. transform nutrients to energy, structural components and waste products, the regulation of hormone secretion and the breakdown of ingested drugs into active metabolites. (ki.se)
Metabolism is the process your body uses to make energy from the food you eat. (medlineplus.gov)
Researchers from the University of Tsukuba have found that exposure to specific types of light before sleep can have variable effects on energy metabolism during sleep. (azooptics.com)
But the effect of night exposure to LED and OLED has not been compared relating to variations in energy metabolism during sleep. (azooptics.com)
Energy metabolism is an important physiological process that is altered by light exposure. (azooptics.com)
Moreover, such findings improve the knowledge of the role of light in energy metabolism during sleep. (azooptics.com)
Metabolism is a term used to indicate the process by which the body converts food and drink into energy. (earthclinic.com)
A slow metabolism can have a detrimental effect on energy, weight and overall health. (earthclinic.com)
Metabolism is how your body changes food into energy. (webmd.com)

Effect of 24-epibrassinolide treatment on the metabolism of eggplant fruits in relation to development of pulp browning under chilling stress. (bvsalud.org)
This study aims to investigate the effect of 24-epibrassinolide (EBR) on the metabolism in relation to development of chilling injury -induced pulp browning of eggplant fruit . (bvsalud.org)

There are also gender differences in alcohol metabolism, and these factors are not always discussed but are nonetheless important. (aspenridgerecoverycenters.com)
Gender differences in alcohol metabolism mean that women and men absorb alcohol much differently. (aspenridgerecoverycenters.com)
How are intoxication levels impacted by gender differences in alcohol metabolism, exactly? (aspenridgerecoverycenters.com)

Other studies suggest that certain dietary components found in spices may exert a beneficial effect on metabolism. (springer.com)
Some beneficial results of antibiotic treatment also confirm this assumption. (biomedcentral.com)
In addition to these changes, several supplements are beneficial for boosting the metabolism including apple cider vinegar, green tea and cayenne. (earthclinic.com)

Likewise, several supplements improve the metabolism. (earthclinic.com)

In the treatment of acute ischemic stroke, immediate recanalization of the occluded artery, using systemic or local thrombolysis, is optimal for restoring the blood flow and rescuing the ischemic brain from complete infarction. (nih.gov)
Because the DSB together with adrenaline repeatedly stimulates metabolism, cortisol tries to calm down its effect on the body, especially on the heart by decreasing salt and leucocytes in the blood. (sense-of-balance-dysfunction.com)

No specific treatments are indicated in Refsum disease, other than dietary restrictions of beef and milk products. (medscape.com)

This study is investigating the safety and efficacy of platelet transfusion as a treatment for infants with thrombocytopenia. (nih.gov)
Six-month follow-up has shown sustained efficacy for this treatment modality. (medscape.com)

Research training will be supported by a core curriculum in metabolism and disease pathobiology, grant writing, ethics, and strategies for successful transition to independence. (uclahealth.org)
Research has shown that rosemary oil can work as a topical hair loss treatment. (davidwolfe.com)
Dr. Shao pursues a research career focusing on understanding cellular mechanisms of acquired epilepsy as well as novel treatments for epilepsy. (hopkinsmedicine.org)

It's one of the top essential oils for enhancing hair growth, with the ability to increase cellular metabolism to stimulate hair growth. (davidwolfe.com)

Metabolism in the human body is a complex whole where everything effects on everything. (sense-of-balance-dysfunction.com)
Salt and fluid metabolisms are an inseparable pair, which is vital to the human body. (sense-of-balance-dysfunction.com)
It's also a key nutrient for a swift metabolism, among the other positive things it does for your body. (webmd.com)

They'll keep your metabolism in check and head off those cravings that can take you off-track. (webmd.com)

Past work has led to the simple hy- side--the less-studied side--of the training by implanting extra copies of pothesis that treatments that decrease mind-brain interaction. (lu.se)

Piracetam, a derivative of the neurotransmitter gamma-aminobutyric acid (GABA), has been investigated as a treatment option for Ménière disease. (lifeextension.com)

Anatomy20

Organisms13

Diseases13

Chemicals and Drugs112

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Psychiatry and Psychology1

Phenomena and Processes73

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science4

Health Care1

Drug metabolism4

Endocrinology3

Inborn errors of2

Diabetes7

Disorders4

Diseases2

Cell Metabolism2

Rats2

Abnormal3

Glycolysis2

Genetics1

Thyroid4

Glucose metabolism1

Clinical4

Genes1

Pathophysiology1

Pathway1

Iodine2

Oxidative2

Metabolic4

Adults2

Hormones1

Substances1

Vitro1

Therapy6

Patients10

Symptoms4

Diets1

Obesity2

Diagnosis and Treatment1

Content1

20011

Prevention4

Molecular1

Disorder2

Energy10

Relation2

Alcohol3

Beneficial3

Supplements1

Blood2

Dietary1

Efficacy2

Research3

Cellular1

Body3

Cravings1

Interaction1

GABA1