• QT-prolonging medications such as clarithromycin, levofloxacin, or haloperidol, when taken concurrently with cytochrome P450 inhibitors, such as fluoxetine, cimetidine, or particular foods including grapefruit, can result in higher-than-normal levels of medications that prolong the QT interval in the bloodstream and therefore increase a person's risk of developing torsades de pointes. (wikipedia.org)
  • Long QT syndrome is a risk factor for developing torsades de pointes, and can either be inherited as congenital mutations of ion channels carrying the cardiac impulse/action potential, or acquired as a result of drugs that block these cardiac ion currents. (wikidoc.org)
  • Being on certain medications also pose a risk for developing torsades de pointes. (wikidoc.org)
  • Beautiful worn as a twisted torsade and bracelet set, these two pieces can be connected, via their crystal-encrusted magnetic clasps, to make one long, stunning necklace. (unoallavolta.com)
  • This Modern Vintage gold-plated torsade link necklace with mini cultured pearls. (joannalauraconstantine.com)
  • Gorgeous pink and fuchsia multi-strand torsade necklace featuring seed beads, frosted glass, art glass sugar beads. (vintagejewelrycollect.com)
  • Which electrolyte imbalance is associated with torsades de pointes? (shakuhachi.net)
  • Drugs that in some reports have been associated with torsades de pointes and/or QT prolongation but at this time lack substantial evidence for causing torsades de pointes. (wikidoc.org)
  • Drug-Induced QT Interval Prolongation and Torsades de Pointes: Role of the pharmacists in risk assessment, prevention and management. (ubc.ca)
  • Mechanisms of fever-induced QT prolongation and torsades de pointes in patients with KCNH2 mutation. (bvsalud.org)
  • This study aimed to determine the mechanism by which KCNH2 mutations cause fever -induced QT prolongation and torsades de pointes (TdP). (bvsalud.org)
  • This was symbolically termed torsade de pointes, or "twisting of the point" about the isoelectric axis, because it reminded the authors of the torsade de pointes movement in ballet. (medscape.com)
  • First jeweller to open on the legendary Place Vendôme in 1812, Chaumet pays tribute to the origins of the Maison with the Torsade de Chaumet collection. (pisaorologeria.com)
  • 유려한 선으로 다이아몬드를 감싼 우아한 디자인의 Torsade de Chaumet 링입니다. (chaumet.com)
  • 쇼메는 Torsade de Chaumet 컬렉션과 함께 1812년 전설적인 방돔 광장에 문을 연 최초의 주얼러인 메종의 기원을 기념합니다. (chaumet.com)
  • Torsades de pointes, torsade de pointes or torsades des pointes (TdP) (/tɔːˌsɑːd də ˈpwæ̃t/, French: [tɔʁsad də pwɛ̃t̪], translated as "twisting of peaks") is a specific type of abnormal heart rhythm that can lead to sudden cardiac death. (wikipedia.org)
  • Patients who are being evaluated for torsades de pointes should be asked about a history of syncope, and family history of long QT syndrome , sudden cardiac death , or sudden infant death syndrome . (wikidoc.org)
  • This leads to a further delay in repolarization and causes early afterdepolarization (EAD), the triggering event for torsade. (medscape.com)
  • Prolonged QT interval reflects prolonged cardiac repolarization, which is a pathogenic factor in the genesis of torsade de pointes. (shakuhachi.net)
  • Drug interactions such as erythromycin or Avelox, taken concomitantly with inhibitors like nitroimidazole , diarrhea , dietary supplements, and various medications like methadone , lithium , tricyclic antidepressants or phenothiazines may also contribute to causing torsades de pointes. (wikidoc.org)
  • Other drugs that can induce torsades de pointes VT include tricyclic antidepressants, phenothiazines, and certain antivirals and antifungals (see CredibleMeds for an up-to-date list). (shakuhachi.net)
  • Torsade de pointes is an uncommon and distinctive form of polymorphic ventricular tachycardia (VT) characterized by a gradual change in the amplitude and twisting of the QRS complexes around the isoelectric line (see the image below). (medscape.com)
  • The term "torsade de pointes" was first described by Dessertenne in 1966, based on the characteristic "twisting" pattern of ventricular tachycardia seen on EKG . (wikidoc.org)
  • Torsades de pointes is defined as the presence of polymorphic ventricular tachycardia with a prolonged QT segment on EKG . (wikidoc.org)
  • The physical exam during or directly after an episode of torsade de pointes, may reveal pallor and diaphoresis , loss of consciousness , and bradycardia followed by tachycardia . (wikidoc.org)
  • Polymorphic ventricular tachycardia is distinguished from torsades de pointes by the absence of prolongation of the QT segment. (wikidoc.org)
  • Torsades de pointes is a ventricular tachycardia, meaning that it is a fast heartbeat with the electrical activity from the ventricles. (shakuhachi.net)
  • When the heart beats faster than usual, as in a case of torsades de pointes, it is called tachycardia. (shakuhachi.net)
  • Torsades de pointes ventricular tachycardia is a specific form of polymorphic ventricular tachycardia in patients with a long QT interval. (msdmanuals.com)
  • The long QT interval responsible for torsades de pointes ventricular tachycardia (TdeP VT) can be acquired, congenital or a combination. (msdmanuals.com)
  • The dispersion of refractoriness permits propagation of the early after-depolarizations and initiation of torsade de pointes ventricular tachycardia. (msdmanuals.com)
  • citation needed] Torsades occurs as both an inherited (linked to at least 17 genes) and as an acquired form caused most often by drugs and/or electrolyte disorders that cause excessive lengthening of the QT interval. (wikipedia.org)
  • Torsade de pointes, often referred to as torsade, is associated with a prolonged QT interval, which may be congenital or acquired. (medscape.com)
  • Torsades de pointes with prolonged QT interval (12-lead ECG of torsades de pointes (TdP) in a 56-year-old white female with low blood potassium (2.4 mmol/L) and low blood magnesium (1.6 mg/dL). (medscape.com)
  • In particular, the use of group IA antidysrhythmic drugs, which tend to prolong the QT interval, can have disastrous consequences in torsade. (medscape.com)
  • The association between torsade and a prolonged QT interval has long been known, but the mechanisms involved at the cellular and ionic levels have been made clearer in approximately the last decade. (medscape.com)
  • We present 4 patients with atrial fibrillation treated with sotalol who developed torsade de pointes due to marked prolongation of the QT interval. (annals.edu.sg)
  • With discontinuation of the erythromycin and aggressive repletion of the magnesium and potassium, no further torsade de pointes occurred and the patient's QT interval returned to normal. (medscape.com)
  • As Seen In Platinum Style Magazine this five-strand pink and white shade pearl torsade features a combination of freshwater biwa and coin pearls and is finished with a large sterling silver clasp. (pattytobin.com)
  • Inspired by the movement of the frieze wrapping the Vendôme column, these virtuoso creations offer a modern and fresh revisiting of the twist - "torsade" in French - in an ode to movement and life. (pisaorologeria.com)
  • 방돔 기둥을 감싼 프리즈의 움직임에서 영감을 받은 컬렉션은 프랑스어로 "토르사드 torsade"라 불리는 꼬임(twist) 디테일을 세련되면서도 생동감 넘치는 디자인으로 재해석해 삶과 움직임을 향한 찬사를 바칩니다. (chaumet.com)
  • This is light colored angel skin and pink coral shell bits fashioned into 3 strands that are twisted together called a Torsade. (tace.com)
  • Certain drugs and combinations of drugs resulting in drug interactions are common contributors to torsades de pointes risk. (wikipedia.org)
  • Tool that categorizes drugs by their potential to cause QT prolongation and/or Torsades de Pointes. (ubc.ca)
  • Table Torsade" is a sculptural bronze table by Diego Giacometti. (rogallery.com)
  • However, the incidence of ham should be commended for pro- stration approved gatifloxacin and torsades de pointes associated with viding added perspective on the mat- moxifloxacin and 8 years since the each of these agents is ripe for further ter of quinolone selection. (cdc.gov)
  • In torsade, the morphology of the QRS complexes varies from beat to beat. (medscape.com)
  • During Torsade de pointes the ventricles depolarize in a circular fashion resulting in QRS complexes with a continuously turning heart axis around the baseline (hence the name Torsade de Pointes ). (wikidoc.org)
  • Torsades de pointes is French for "twisting of points" and refers to when the heart's two lower chambers or ventricles, beat faster than the upper chambers, which are known as the atria. (shakuhachi.net)
  • Courtesy of Wikimedia Commons [Author Jason E Roediger, CCT, CRAT, https://commons.wikimedia.org/wiki/File:Torsades_de_Pointes_TdP.png]. (medscape.com)
  • In the case of torsades de pointes (TdP), the heart's two lower chambers, called the ventricles, beat faster than and out of sync with the upper chambers, called the atria. (shakuhachi.net)
  • In one example, the gastrokinetic drug cisapride (Propulsid) was withdrawn from the US market in 2000 after it was linked to deaths caused by long QT syndrome-induced torsades de pointes. (wikipedia.org)
  • Torsades de pointes should be differentiated from other conditions or disorders that may present in a similar way, such as other arrhythmias , drug toxicity, syncope and other cardiac conditions. (wikidoc.org)
  • One patient had been treated with sotalol for more than 10 months before developing torsade de pointes precipitated by hypokalaemia, while another had tolerated sotalol for a 3-month period before the drug was discontinued, and only developed torsade de pointes when the drug was restarted 2 years later. (annals.edu.sg)
  • Present methodologies for assessing drug-induced torsades de pointes (TdP) are woefully inadequate in terms of their specificity to select pharmaceutical agents, which are human arrhythmia toxicants. (hesiglobal.org)
  • Frothingham and published in 2001 "wholesale change" to the newer comparisons, particularly with respect would provide meaningful guidance quinolones is an appropriate response to torsades de pointes, a rare, life- to clinicians. (cdc.gov)
  • Magnesium sulphate suppresses torsade by decreasing the influx of calcium ions, which in turn results in decreased amplitude of EADs. (shakuhachi.net)
  • The Care Trajectories-Enriched Data ( TorSaDE ) cohort (Int J Epidemiol. (lu.se)